Ddx54 (DEAD-box helicase 54) - Rat Genome Database

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Gene: Ddx54 (DEAD-box helicase 54) Rattus norvegicus
Analyze
Symbol: Ddx54
Name: DEAD-box helicase 54
RGD ID: 1562539
Description: Predicted to enable several functions, including RNA helicase activity; nuclear estrogen receptor binding activity; and transcription corepressor activity. Predicted to be involved in rRNA processing. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human DDX54 (DEAD-box helicase 54); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent RNA helicase DDX54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; LOC360815; RGD1562539; similar to ATP-dependent RNA-helicase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,595,298 - 41,610,560 (-)NCBIGRCr8
mRatBN7.21235,934,713 - 35,949,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,934,716 - 35,972,523 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1237,115,128 - 37,129,581 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,726,345 - 37,740,799 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,778,808 - 36,793,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01241,469,642 - 41,484,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,470,557 - 41,485,122 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,327,743 - 43,343,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,103,084 - 37,117,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1237,596,914 - 37,611,356 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi apparatus  (IEA,ISO)
nucleolus  (IBA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12466272   PMID:19946888   PMID:22658674   PMID:22681889   PMID:37377223  


Genomics

Comparative Map Data
Ddx54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,595,298 - 41,610,560 (-)NCBIGRCr8
mRatBN7.21235,934,713 - 35,949,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,934,716 - 35,972,523 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1237,115,128 - 37,129,581 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,726,345 - 37,740,799 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,778,808 - 36,793,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01241,469,642 - 41,484,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,470,557 - 41,485,122 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01243,327,743 - 43,343,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41237,103,084 - 37,117,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1237,596,914 - 37,611,356 (-)NCBICelera
Cytogenetic Map12q16NCBI
DDX54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812113,157,173 - 113,185,478 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12113,157,173 - 113,185,479 (-)EnsemblGRCh38hg38GRCh38
GRCh3712113,594,978 - 113,623,283 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612112,079,361 - 112,107,667 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412112,057,698 - 112,086,004NCBI
Celera12113,221,967 - 113,250,107 (-)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12110,607,691 - 110,635,997 (-)NCBIHuRef
CHM1_112113,563,241 - 113,591,547 (-)NCBICHM1_1
T2T-CHM13v2.012113,133,817 - 113,162,122 (-)NCBIT2T-CHM13v2.0
Ddx54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395120,751,182 - 120,766,657 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5120,750,804 - 120,766,657 (+)EnsemblGRCm39 Ensembl
GRCm385120,613,082 - 120,628,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5120,612,739 - 120,628,592 (+)EnsemblGRCm38mm10GRCm38
MGSCv375121,063,139 - 121,078,601 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365120,873,747 - 120,889,209 (+)NCBIMGSCv36mm8
Celera5117,698,330 - 117,713,837 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map560.63NCBI
Ddx54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,494,188 - 9,509,872 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,493,840 - 9,509,916 (-)NCBIChiLan1.0ChiLan1.0
DDX54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210121,247,419 - 121,274,468 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112121,243,816 - 121,270,866 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012110,763,319 - 110,790,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112114,144,659 - 114,173,129 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12114,144,664 - 114,173,127 (-)Ensemblpanpan1.1panPan2
DDX54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12610,562,773 - 10,568,631 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2610,550,019 - 10,568,763 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2610,669,034 - 10,690,854 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02610,791,136 - 10,812,857 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,792,176 - 10,813,194 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12610,764,808 - 10,786,758 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,827,627 - 10,849,426 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,876,383 - 10,898,344 (-)NCBIUU_Cfam_GSD_1.0
Ddx54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118148,563,980 - 148,575,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366683,061,796 - 3,075,426 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366683,062,868 - 3,074,769 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1438,645,891 - 38,668,265 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11438,650,660 - 38,668,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,110,096 - 41,123,364 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDX54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111108,407,623 - 108,437,188 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11108,404,719 - 108,437,168 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037136,661,013 - 136,687,963 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,264,888 - 19,278,934 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474719,264,836 - 19,279,251 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddx54
65 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:149
Interacting mature miRNAs:169
Transcripts:ENSRNOT00000001859
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122860752637691617Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
AI137218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,935,904 - 35,936,144 (+)MAPPERmRatBN7.2
Rnor_6.01241,470,834 - 41,471,073NCBIRnor6.0
Rnor_5.01243,328,935 - 43,329,174UniSTSRnor5.0
RGSC_v3.41237,103,477 - 37,103,716UniSTSRGSC3.4
Celera1237,597,307 - 37,597,546UniSTS
RH 3.4 Map12630.6UniSTS
Cytogenetic Map12q16UniSTS
RH138566  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21235,937,450 - 35,938,536 (+)MAPPERmRatBN7.2
Rnor_6.01241,472,380 - 41,473,465NCBIRnor6.0
Rnor_5.01243,330,481 - 43,331,566UniSTSRnor5.0
RGSC_v3.41237,105,023 - 37,106,108UniSTSRGSC3.4
Celera1237,598,853 - 37,599,938UniSTS
RH 3.4 Map12633.6UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 49 33 19 33 2 68 33 41 11
Low 14 8 8 8 8 9 6 2 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001859   ⟹   ENSRNOP00000001859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,934,716 - 35,950,029 (-)Ensembl
Rnor_6.0 Ensembl1241,470,557 - 41,485,122 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000001860   ⟹   ENSRNOP00000001860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,955,525 - 35,972,447 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096266   ⟹   ENSRNOP00000089354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,955,535 - 35,972,523 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111779   ⟹   ENSRNOP00000080555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,934,716 - 35,967,001 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112938   ⟹   ENSRNOP00000079683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1235,955,534 - 35,967,001 (-)Ensembl
RefSeq Acc Id: NM_001191548   ⟹   NP_001178477
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,596,097 - 41,610,538 (-)NCBI
mRatBN7.21235,935,512 - 35,949,953 (-)NCBI
Rnor_6.01241,470,441 - 41,484,882 (-)NCBI
Rnor_5.01243,327,743 - 43,343,059 (-)NCBI
Celera1237,596,914 - 37,611,356 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249397   ⟹   XP_006249459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,595,298 - 41,610,560 (-)NCBI
mRatBN7.21235,934,713 - 35,949,955 (-)NCBI
Rnor_6.01241,469,642 - 41,484,887 (-)NCBI
Rnor_5.01243,327,743 - 43,343,059 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249398   ⟹   XP_006249460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81241,595,298 - 41,610,539 (-)NCBI
mRatBN7.21235,934,713 - 35,949,956 (-)NCBI
Rnor_6.01241,469,642 - 41,484,887 (-)NCBI
Rnor_5.01243,327,743 - 43,343,059 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178477 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249459 (Get FASTA)   NCBI Sequence Viewer  
  XP_006249460 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13773 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001859
  ENSRNOP00000001859.8
  ENSRNOP00000080555.1
Reference Protein Sequences
RefSeq Acc Id: NP_001178477   ⟸   NM_001191548
- UniProtKB: D3ZHY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249460   ⟸   XM_006249398
- Peptide Label: isoform X2
- UniProtKB: D3ZHY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249459   ⟸   XM_006249397
- Peptide Label: isoform X1
- UniProtKB: D3ZHY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001859   ⟸   ENSRNOT00000001859
RefSeq Acc Id: ENSRNOP00000089354   ⟸   ENSRNOT00000096266
RefSeq Acc Id: ENSRNOP00000001860   ⟸   ENSRNOT00000001860
RefSeq Acc Id: ENSRNOP00000080555   ⟸   ENSRNOT00000111779
RefSeq Acc Id: ENSRNOP00000079683   ⟸   ENSRNOT00000112938
Protein Domains
DEAD-box RNA helicase Q   Helicase ATP-binding   Helicase C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHY6-F1-model_v2 AlphaFold D3ZHY6 1-914 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562539 AgrOrtholog
BioCyc Gene G2FUF-19184 BioCyc
Ensembl Genes ENSRNOG00000001377 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001859.8 UniProtKB/TrEMBL
  ENSRNOT00000111779.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DBP10CT UniProtKB/TrEMBL
  DDX54/DBP10 UniProtKB/TrEMBL
  DEAD-like_N UniProtKB/TrEMBL
  DNA/RNA_helicase_C UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAD/DEAH_N UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA-helicase_DEAD-box_CS UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
NCBI Gene 360815 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE RHLE-RELATED UniProtKB/TrEMBL
  RNA HELICASE UniProtKB/TrEMBL
Pfam DBP10CT UniProtKB/TrEMBL
  DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PhenoGen Ddx54 PhenoGen
PROSITE DEAD_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001377 RatGTEx
SMART DBP10CT UniProtKB/TrEMBL
  DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZQB0_RAT UniProtKB/TrEMBL
  D3ZHY6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Ddx54  DEAD-box helicase 54  Ddx54  DEAD (Asp-Glu-Ala-Asp) box polypeptide 54  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Ddx54  DEAD (Asp-Glu-Ala-Asp) box polypeptide 54  RGD1562539_predicted  similar to ATP-dependent RNA-helicase (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562539_predicted  similar to ATP-dependent RNA-helicase (predicted)  LOC360815  similar to ATP-dependent RNA-helicase  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360815  similar to ATP-dependent RNA-helicase      Symbol and Name status set to provisional 70820 PROVISIONAL