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Gene: Tceal3 (transcription elongation factor A like 3) Rattus norvegicus

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Symbol:

Tceal3 (Ensembl: Tceal6)

Name:

transcription elongation factor A like 3 (Ensembl:transcription elongation factor A like 6)

RGD ID:

1562504

Description:

Orthologous to several human genes including TCEAL3 (transcription elongation factor A like 3) and TCEAL5 (transcription elongation factor A like 5); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; gentamycin.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC501628; RGD1562504; similar to transcription elongation factor A (SII)-like 3; transcription elongation factor A (SII)-like 3; transcription elongation factor A protein-like 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	104,802,966 - 104,804,926 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	104,802,806 - 104,805,331 (+)	Ensembl				GRCr8
mRatBN7.2	X	100,010,677 - 100,012,637 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	100,010,690 - 100,012,654 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	X	98,337,873 - 98,338,472 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	102,140,850 - 102,142,810 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	105,639,533 - 105,641,493 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	103,208,702 - 103,210,663 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	107,322,077 - 107,324,054 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	102,370,158 - 102,370,757 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	X	107,323,215 - 107,323,814 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	107,206,850 - 107,208,820 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	124,311,866 - 124,314,022 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	100,847,323 - 100,849,299 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

7,12-dimethyltetraphene (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

isobutanol (ISO)

maneb (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP)

paraquat (ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

temozolomide (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

valproic acid (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:25002582

Genomics

Comparative Map Data

Tceal3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	104,802,966 - 104,804,926 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	104,802,806 - 104,805,331 (+)	Ensembl				GRCr8
mRatBN7.2	X	100,010,677 - 100,012,637 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	100,010,690 - 100,012,654 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	X	98,337,873 - 98,338,472 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	102,140,850 - 102,142,810 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	105,639,533 - 105,641,493 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	103,208,702 - 103,210,663 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	107,322,077 - 107,324,054 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	102,370,158 - 102,370,757 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	X	107,323,215 - 107,323,814 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	107,206,850 - 107,208,820 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	124,311,866 - 124,314,022 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	100,847,323 - 100,849,299 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

TCEAL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	103,607,963 - 103,609,927 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	103,607,451 - 103,629,690 (+)	Ensembl			hg38	GRCh38
GRCh37	X	102,862,891 - 102,864,855 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	102,749,490 - 102,751,511 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	102,668,978 - 102,670,999	NCBI
Celera	X	103,301,848 - 103,303,869 (+)	NCBI		Celera
Cytogenetic Map	X	q22.2	NCBI
HuRef	X	92,518,565 - 92,523,170 (+)	NCBI		HuRef
CHM1_1	X	102,755,836 - 102,757,857 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	102,054,947 - 102,056,911 (+)	NCBI		T2T-CHM13v2.0

Tceal3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	135,491,586 - 135,569,127 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	135,491,591 - 135,569,127 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	136,590,837 - 136,668,378 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	136,590,842 - 136,668,378 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	133,200,914 - 133,202,916 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	132,012,817 - 132,014,741 (+)	NCBI		MGSCv36	mm8
Celera	X	119,949,866 - 119,951,803 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	59.1	NCBI

LOC100991183
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	103,219,383 - 103,221,429 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	103,223,032 - 103,224,988 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	92,836,622 - 92,838,858 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	103,217,899 - 103,219,838 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

TCEAL3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	77,021,480 - 77,023,881 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	63,250,465 - 63,252,849 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	78,640,224 - 78,642,608 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	78,640,187 - 78,642,355 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	76,117,583 - 76,119,967 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	77,804,404 - 77,806,790 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	77,571,450 - 77,573,834 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tceal3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	76,945,033 - 76,947,270 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	10,710,756 - 10,712,621 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	10,710,694 - 10,712,884 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TCEAL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	84,485,887 - 84,490,011 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	98,276,435 - 98,278,805 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Tceal3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624954	354,100 - 356,126 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tceal3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	88,426,145 - 88,427,044 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tceal3
16 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	49
Count of miRNA genes:	46
Interacting mature miRNAs:	46
Transcripts:	ENSRNOT00000071874
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	80434318	125434318	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	92979612	117740458	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
5	1	18	38	9	71	37	11	31	29	32	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001053421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	FQ213674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000071874 ⟹ ENSRNOP00000064154

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	98,337,873 - 98,338,472 (-)	Ensembl
Rnor_6.0 Ensembl	X	107,323,215 - 107,323,814 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000074255 ⟹ ENSRNOP00000066958

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	100,010,690 - 100,012,654 (+)	Ensembl
Rnor_6.0 Ensembl	2	102,370,158 - 102,370,757 (-)	Ensembl

RefSeq Acc Id:

NM_001401190 ⟹ NP_001388119

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	104,802,966 - 104,804,926 (+)	NCBI
mRatBN7.2	X	100,010,677 - 100,012,637 (+)	NCBI

RefSeq Acc Id:

XM_063280254 ⟹ XP_063136324

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	104,803,260 - 104,804,926 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388119	(Get FASTA)	NCBI Sequence Viewer
	XP_063136324	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000066958

Ensembl Acc Id:

ENSRNOP00000064154 ⟸ ENSRNOT00000071874

Ensembl Acc Id:

ENSRNOP00000066958 ⟸ ENSRNOT00000074255

RefSeq Acc Id:	NP_001388119 ⟸ NM_001401190
- UniProtKB:	M0RBL8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063136324 ⟸ XM_063280254
- Peptide Label:	isoform X1
- UniProtKB:	M0RBL8 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RBL8-F1-model_v2	AlphaFold	M0RBL8	1-199	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562504	AgrOrtholog
BioCyc Gene	G2FUF-1616	BioCyc
Ensembl Genes	ENSRNOG00000046390	Ensembl, ENTREZGENE
	ENSRNOG00000049020	Ensembl
Ensembl Transcript	ENSRNOT00000074255	ENTREZGENE
NCBI Gene	501628	ENTREZGENE
PhenoGen	Tceal3	PhenoGen
RatGTEx	ENSRNOG00000046390	RatGTEx
	ENSRNOG00000049020	RatGTEx
UniProt	M0RBL8	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-19	Tceal3	transcription elongation factor A like 3	Tceal3	transcription elongation factor A (SII)-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-29	Tceal3	transcription elongation factor A (SII)-like 3	RGD1562504	similar to transcription elongation factor A (SII)-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1562504	similar to transcription elongation factor A (SII)-like 3	RGD1562504_predicted	similar to transcription elongation factor A (SII)-like 3 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1562504_predicted	similar to transcription elongation factor A (SII)-like 3 (predicted)	LOC501628	similar to transcription elongation factor A (SII)-like 3	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501628	similar to transcription elongation factor A (SII)-like 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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