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Gene: Dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta) Rattus norvegicus

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Symbol:

Dnajc5b

Name:

DnaJ heat shock protein family (Hsp40) member C5 beta

RGD ID:

1562486

Description:

Predicted to be located in transport vesicle membrane. Orthologous to human DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CSP-beta; cysteine string protein beta; DnaJ (Hsp40) homolog, subfamily C, member 5 beta; dnaJ homolog subfamily C member 5B; LOC499579; RGD1562486; similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein); similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (Beta-CSP)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	103,889,863 - 103,982,413 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	103,889,919 - 103,982,423 (+)	Ensembl				GRCr8
mRatBN7.2	2	101,973,726 - 102,066,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	101,973,793 - 102,066,275 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	108,497,530 - 108,590,544 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	106,618,657 - 106,711,671 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	101,587,028 - 101,679,144 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	2	103,296,157 - 103,389,131 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	2	103,359,121 - 103,452,100 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	2	103,216,355 - 103,309,333 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	2	103,021,545 - 103,114,519 (+)	NCBI		F344_StmMcwi
Rnor_6.0	2	104,290,726 - 104,382,846 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	104,290,726 - 104,382,878 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	124,014,181 - 124,105,971 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	104,595,007 - 104,687,531 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	97,368,369 - 97,459,954 (+)	NCBI		Celera
Cytogenetic Map	2	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-chloropropane-1,2-diol (EXP)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

ethyl methanesulfonate (ISO)

fenofibrate (EXP)

fonofos (ISO)

furan (EXP)

ibuprofen (EXP)

methyl methanesulfonate (ISO)

paracetamol (ISO)

parathion (ISO)

pirinixic acid (ISO)

propanal (ISO)

succimer (ISO)

tamoxifen (ISO)

terbufos (ISO)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

transport vesicle membrane (IEA)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Endoplasmic Reticulum-associated degradation pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Dnajc5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	103,889,863 - 103,982,413 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	103,889,919 - 103,982,423 (+)	Ensembl				GRCr8
mRatBN7.2	2	101,973,726 - 102,066,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	101,973,793 - 102,066,275 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	108,497,530 - 108,590,544 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	106,618,657 - 106,711,671 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	101,587,028 - 101,679,144 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	2	103,296,157 - 103,389,131 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	2	103,359,121 - 103,452,100 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	2	103,216,355 - 103,309,333 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	2	103,021,545 - 103,114,519 (+)	NCBI		F344_StmMcwi
Rnor_6.0	2	104,290,726 - 104,382,846 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	104,290,726 - 104,382,878 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	124,014,181 - 124,105,971 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	104,595,007 - 104,687,531 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	97,368,369 - 97,459,954 (+)	NCBI		Celera
Cytogenetic Map	2	q24	NCBI

DNAJC5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	66,014,978 - 66,101,245 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	66,021,553 - 66,101,252 (+)	Ensembl			hg38	GRCh38
GRCh37	8	66,927,213 - 67,013,480 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	67,096,345 - 67,175,309 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	67,096,348 - 67,174,920	NCBI
Celera	8	62,925,510 - 63,004,473 (+)	NCBI		Celera
Cytogenetic Map	8	q13.1	NCBI
HuRef	8	62,423,812 - 62,502,777 (+)	NCBI		HuRef
CHM1_1	8	66,988,411 - 67,067,412 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	66,440,668 - 66,526,936 (+)	NCBI		T2T-CHM13v2.0

Dnajc5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	19,562,755 - 19,665,026 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	19,562,759 - 19,665,026 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	19,508,591 - 19,610,862 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	19,508,595 - 19,610,862 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	19,408,595 - 19,510,862 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	19,700,803 - 19,803,013 (+)	NCBI		MGSCv36	mm8
Celera	3	19,501,409 - 19,603,629 (+)	NCBI		Celera
Cytogenetic Map	3	A2	NCBI
cM Map	3	5.55	NCBI

Dnajc5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	13,071,867 - 13,158,000 (-)	Ensembl
ChiLan1.0	NW_004955444	13,069,490 - 13,162,053 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAJC5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	81,755,501 - 81,833,270 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	57,395,076 - 57,471,801 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	62,554,228 - 62,639,272 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	64,223,180 - 64,306,672 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	64,229,648 - 64,306,672 (+)	Ensembl			panPan2	panpan1.1

DNAJC5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	15,673,793 - 15,762,929 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	15,673,873 - 15,762,082 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	15,994,902 - 16,077,443 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	15,758,743 - 15,841,254 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	15,758,842 - 15,840,688 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	15,782,268 - 15,870,874 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	15,890,624 - 15,973,215 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	16,146,898 - 16,228,994 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dnajc5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	66,866,017 - 66,944,085 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	7,841,637 - 7,928,203 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	7,841,645 - 7,897,029 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJC5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	68,557,670 - 68,641,134 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	68,557,670 - 68,641,134 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	74,724,844 - 74,808,716 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJC5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	61,917,938 - 61,979,096 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	61,925,939 - 61,978,604 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	79,532,427 - 79,614,280 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajc5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	25,288,097 - 25,336,107 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624744	25,288,267 - 25,349,693 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dnajc5b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	134,441,289 - 134,521,990 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dnajc5b
998 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	183
Count of miRNA genes:	144
Interacting mature miRNAs:	160
Transcripts:	ENSRNOT00000017387
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	61556902	106556902	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1598865	Bp296	Blood pressure QTL 296	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	82947902	127947902	Rat
1578772	Stresp14	Stress response QTL 14	5	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	2	84056790	132859658	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	40306867	124537199	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
61465	Bp13	Blood pressure QTL 13	3.3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	78269809	104744824	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
2317886	Alcrsp23	Alcohol response QTL 23	2.4	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	95142371	140142371	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	41801363	104744824	Rat
2317058	Aia13	Adjuvant induced arthritis QTL 13	2.9		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	2	78269809	123269809	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1300155	Bp174	Blood pressure QTL 174	4.09		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	44537979	112567334	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	61051541	105724065	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1359035	Bp276	Blood pressure QTL 276			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	100807373	145807373	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
2299162	Iddm32	Insulin dependent diabetes mellitus QTL 32	2.36		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	93602631	145807373	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	61051883	104684275	Rat
61392	Bp6	Blood pressure QTL 6	7		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	82214549	127214549	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	61051541	105724065	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	60861391	105861391	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
2306903	Bp336	Blood pressure QTL 336		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	38426449	111295694	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	61051541	143746880	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

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alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	6	67	78	53	52	31	18	31	6	196	103	62	50	47	21

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017387 ⟹ ENSRNOP00000017387

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	103,889,919 - 103,982,423 (+)	Ensembl
mRatBN7.2 Ensembl	2	101,973,793 - 102,066,275 (+)	Ensembl
Rnor_6.0 Ensembl	2	104,290,726 - 104,382,878 (+)	Ensembl

RefSeq Acc Id:

NM_001109180 ⟹ NP_001102650

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	103,889,930 - 103,982,413 (+)	NCBI
mRatBN7.2	2	101,973,793 - 102,066,275 (+)	NCBI
Dahl_SR_JrHsd	2	103,296,157 - 103,389,131 (+)	NCBI
Lyon_Normotensive	2	103,359,121 - 103,452,100 (+)	NCBI
Lyon_Hypertensive	2	103,216,355 - 103,309,333 (+)	NCBI
F344_StmMcwi	2	103,021,545 - 103,114,519 (+)	NCBI
Rnor_6.0	2	104,290,760 - 104,382,846 (+)	NCBI
Rnor_5.0	2	124,014,181 - 124,105,971 (+)	NCBI
RGSC_v3.4	2	104,595,007 - 104,687,531 (+)	RGD
Celera	2	97,368,369 - 97,459,954 (+)	RGD

Sequence:

show sequence

AGTTATTGACAGAGCAGAGGAAGAACACTACTGGAAGGACCCAGAAGGATCAGCCAGCCATGCC
TTCAGTTCAGGTACAAGATTGAGAAATGGCATGTAACATACCTAATCAAAGACAGCGGGCTATG
TCAACATCAGGAGAAAGTCTGTATGAAATCCTTGGTCTGCATAAGGGAGCATCATGTGAAGAAA
TTAAGAAAACCTACAGAAAATTAGCCCTGCGACACCATCCGGACAAGAATCCAGATGATCCATC
TGCTGCTGAGAAGTTTAAAGAAATCAACAATGCCCACACAATCCTCACTGACAACTCAAAGAGA
AACATATACGACAAGTATGGATCATTGGGACTCTACGTGGCCGAGCAATTTGGAGATGAAAACG
TTAACACATACTTCATGCTGTCAAGCTGGTGGGCAAAGACCCTGTTCATCATCATTGGCCTCTT
GACCGGCTGCTATTTTTGCTGCTGCCTATGCTGCTGCTGCAATTGTTGTTGTGGACATTGTCGG
CCCAAGACATCGACACCAGAAGAGGAGTTCTATGTGTCACCAGAGGACCTCGAGGAGCAGATCA
GAACTGATATGGAGAAAGATATGGACTTTCCAGTTGTTCTCCAGCCTACAAATACAAATGAGAA
AACACAGCTAATCAGAGAAGGATCTCGAAGTTACTGCACAGACTCTTGATGATGGGCTCATGGA
GGGTCCACAGCTCCTCTTTTTGGTTCAGCCGTGTCTCTGGGTTGTCATGAGGGAGGTGCAAACA
TGAAATGCTGTGAACATATTCACATTTGTATTTTATTTTTAGGTTAAGGGGAAGATGATTGCTA
CATAATTTTCTCAGACTTTCTCTTTGAGTAGAATCCTAATGAAAAGCATTCAGTTTATGAATAA
AGGCCTGAAGAGTTG

hide sequence

RefSeq Acc Id:

XM_017591027 ⟹ XP_017446516

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	103,889,863 - 103,982,288 (+)	NCBI
mRatBN7.2	2	101,973,726 - 102,066,275 (+)	NCBI
Rnor_6.0	2	104,290,726 - 104,382,719 (+)	NCBI

Sequence:

show sequence

CTTAGCATCTGAGAAAGAAAAGTAACAGAAGTTCAGTTATTGACAGAGCAGAGGAAGAACACTA
CTGGAAGGACCCAGAAGGATCAGCCAGCCATGCCTTCAGTTCAGATTGAGAAATGGCATGTAAC
ATACCTAATCAAAGACAGCGGGCTATGTCAACATCAGGAGAAAGTCTGTATGAAATCCTTGGTC
TGCATAAGGGAGCATCATGTGAAGAAATTAAGAAAACCTACAGAAAATTAGCCCTGCGACACCA
TCCGGACAAGAATCCAGATGATCCATCTGCTGCTGAGAAGTTTAAAGAAATCAACAATGCCCAC
ACAATCCTCACTGACAACTCAAAGAGAAACATATACGACAAGTATGGATCATTGGGACTCTACG
TGGCCGAGCAATTTGGAGATGAAAACGTTAACACATACTTCATGCTGTCAAGCTGGTGGGCAAA
GACCCTGTTCATCATCATTGGCCTCTTGACCGGCTGCTATTTTTGCTGCTGCCTATGCTGCTGC
TGCAATTGTTGTTGTGGACATTGTCGGCCCAAGACATCGACACCAGAAGAGGAGTTCTATGTGT
CACCAGAGGACCTCGAGGAGCAGATCAGAACTGATATGGAGAAAGATATGGACTTTCCAGTTGT
TCTCCAGCCTACAAATACAAATGAGAAAACACAGCTAATCAGAGAAGGATCTCGAAGTTACTGC
ACAGACTCTTGATGATGGGCTCATGGAGGGTCCACAGCTCCTCTTTTTGGTTCAGCCGTGTCTC
TGGGTTGTCATGAGGGAGGTGCAAACATGAAATGCTGTGAACA

hide sequence

RefSeq Acc Id:

XM_017591029 ⟹ XP_017446518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	103,889,907 - 103,982,412 (+)	NCBI
mRatBN7.2	2	101,973,800 - 102,066,275 (+)	NCBI
Rnor_6.0	2	104,290,726 - 104,382,719 (+)	NCBI

Sequence:

show sequence

CTTAGCATCTGAGAAAGAAAAGTAACAGAAGTTCAGTTATTGACAGAGCAGAGGAAGAACACTA
CTGGAAGGACCCAGAAGGATCAGCCAGCCATGCCTTCAGTTCAGGGATAACCAATTGACTGATA
AAGTAACAAATGAAAAGTAACCCGACTCCACTGACCTGTGCAACCCAGCAGGAAGGATGGAAAA
GAGGGGCCTTTAGCCTTGCCACAGTAGGACGGGTATGGAGTAGAGCTCTGTTCCTCGCTGCCTC
CGTCTTCTGTCTCTCTGCACATCAGTTTCCAGGTTTGGTGAAAACAGCAGAATTGGAGTCATAG
GAACAGATTGAGAAATGGCATGTAACATACCTAATCAAAGACAGCGGGCTATGTCAACATCAGG
AGAAAGTCTGTATGAAATCCTTGGTCTGCATAAGGGAGCATCATGTGAAGAAATTAAGAAAACC
TACAGAAAATTAGCCCTGCGACACCATCCGGACAAGAATCCAGATGATCCATCTGCTGCTGAGA
AGTTTAAAGAAATCAACAATGCCCACACAATCCTCACTGACAACTCAAAGAGAAACATATACGA
CAAGTATGGATCATTGGGACTCTACGTGGCCGAGCAATTTGGAGATGAAAACGTTAACACATAC
TTCATGCTGTCAAGCTGGTGGGCAAAGACCCTGTTCATCATCATTGGCCTCTTGACCGGCTGCT
ATTTTTGCTGCTGCCTATGCTGCTGCTGCAATTGTTGTTGTGGACATTGTCGGCCCAAGACATC
GACACCAGAAGAGGAGTTCTATGTGTCACCAGAGGACCTCGAGGAGCAGATCAGAACTGATATG
GAGAAAGATATGGACTTTCCAGTTGTTCTCCAGCCTACAAATACAAATGAGAAAACACAGCTAA
TCAGAGAAGGATCTCGAAGTTACTGCACAGACTCTTGATGATGGGCTCATGGAGGGTCCACAGC
TCCTCTTTTTGGTTCAGCCGTGTCTCTGGGTTGTCATGAGGGAGGTGCAAACATGAAATGCTGT
GAACA

hide sequence

RefSeq Acc Id:

XM_063282353 ⟹ XP_063138423

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	103,889,895 - 103,982,412 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102650	(Get FASTA)	NCBI Sequence Viewer
	XP_017446516	(Get FASTA)	NCBI Sequence Viewer
	XP_017446518	(Get FASTA)	NCBI Sequence Viewer
	XP_063138423	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D3ZD82	(Get FASTA)	NCBI Sequence Viewer
	EDM01065	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017387
	ENSRNOP00000017387.3

RefSeq Acc Id:

NP_001102650 ⟸ NM_001109180

- UniProtKB:

D3ZD82 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MACNIPNQRQRAMSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEI
NNAHTILTDNSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCC
LCCCCNCCCGHCRPKTSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGS
RSYCTDS

hide sequence

RefSeq Acc Id:	XP_017446518 ⟸ XM_017591029
- Peptide Label:	isoform X1
- UniProtKB:	D3ZD82 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MACNIPNQRQRAMSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEI NNAHTILTDNSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCC LCCCCNCCCGHCRPKTSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGS RSYCTDS hide sequence

RefSeq Acc Id:	XP_017446516 ⟸ XM_017591027
- Peptide Label:	isoform X1
- UniProtKB:	D3ZD82 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MACNIPNQRQRAMSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEI NNAHTILTDNSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCC LCCCCNCCCGHCRPKTSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGS RSYCTDS hide sequence

Ensembl Acc Id:

ENSRNOP00000017387 ⟸ ENSRNOT00000017387

RefSeq Acc Id:	XP_063138423 ⟸ XM_063282353
- Peptide Label:	isoform X1
- UniProtKB:	D3ZD82 (UniProtKB/Swiss-Prot)

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZD82-F1-model_v2	AlphaFold	D3ZD82	1-199	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691255

Promoter ID:

EPDNEW_R1779

Type:

multiple initiation site

Name:

Dnajc5b_1

Description:

DnaJ heat shock protein family member C5 beta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	104,290,760 - 104,290,820	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562486	AgrOrtholog
BioCyc Gene	G2FUF-53624	BioCyc
Ensembl Genes	ENSRNOG00000012851	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000017387	ENTREZGENE
	ENSRNOT00000017387.6	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.287.110	UniProtKB/Swiss-Prot
InterPro	DnaJ_C_subfamily_member5	UniProtKB/Swiss-Prot
	DnaJ_domain	UniProtKB/Swiss-Prot
	J_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:499579	UniProtKB/Swiss-Prot
NCBI Gene	499579	ENTREZGENE
PANTHER	DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG	UniProtKB/Swiss-Prot
	DNAJ HOMOLOG SUBFAMILY C MEMBER 5B	UniProtKB/Swiss-Prot
Pfam	DnaJ	UniProtKB/Swiss-Prot
PhenoGen	Dnajc5b	PhenoGen
PRINTS	JDOMAIN	UniProtKB/Swiss-Prot
PROSITE	DNAJ_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000012851	RatGTEx
SMART	DnaJ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46565	UniProtKB/Swiss-Prot
UniProt	D3ZD82	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-25	Dnajc5b	DnaJ heat shock protein family (Hsp40) member C5 beta	Dnajc5b	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-29	Dnajc5b	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	RGD1562486_predicted	similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-10	RGD1562486_predicted	similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (predicted)		similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (Beta-CSP) (predicted)	Name updated	1299863	APPROVED
2006-03-07	RGD1562486_predicted	similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (Beta-CSP) (predicted)	LOC499579	similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (Beta-CSP)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499579	similar to DnaJ homolog subfamily C member 5B (Beta cysteine string protein) (Beta-CSP)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)