Tmem156 (transmembrane protein 156) - Rat Genome Database

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Gene: Tmem156 (transmembrane protein 156) Rattus norvegicus
Analyze
Symbol: Tmem156
Name: transmembrane protein 156
RGD ID: 1562424
Description: Predicted to be located in membrane. Orthologous to human TMEM156 (transmembrane protein 156); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC498365; LOC498365
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,568,131 - 43,606,109 (+)NCBIGRCr8
mRatBN7.21443,221,464 - 43,252,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,223,381 - 43,252,449 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,577,453 - 43,613,094 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,877,412 - 44,913,053 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01443,357,577 - 43,393,221 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,888,902 - 44,918,377 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,889,287 - 44,918,373 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,700,605 - 44,731,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,925,110 - 45,954,140 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1442,367,690 - 42,396,765 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Tmem156
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,568,131 - 43,606,109 (+)NCBIGRCr8
mRatBN7.21443,221,464 - 43,252,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,223,381 - 43,252,449 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,577,453 - 43,613,094 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,877,412 - 44,913,053 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01443,357,577 - 43,393,221 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,888,902 - 44,918,377 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,889,287 - 44,918,373 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,700,605 - 44,731,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,925,110 - 45,954,140 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1442,367,690 - 42,396,765 (+)NCBICelera
Cytogenetic Map14p11NCBI
TMEM156
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38438,966,744 - 39,032,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl438,966,744 - 39,032,922 (-)EnsemblGRCh38hg38GRCh38
GRCh37438,968,365 - 39,034,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36438,644,817 - 38,710,436 (-)NCBINCBI36Build 36hg18NCBI36
Celera439,406,541 - 39,471,858 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef438,293,340 - 38,358,636 (-)NCBIHuRef
CHM1_1438,968,005 - 39,033,566 (-)NCBICHM1_1
T2T-CHM13v2.0438,936,798 - 39,002,606 (-)NCBIT2T-CHM13v2.0
Tmem156
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,215,558 - 65,249,524 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,211,689 - 65,249,475 (-)EnsemblGRCm39 Ensembl
GRCm38565,058,215 - 65,092,181 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,054,346 - 65,092,132 (-)EnsemblGRCm38mm10GRCm38
MGSCv37565,456,174 - 65,482,794 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,333,482 - 65,370,764 (-)NCBIMGSCv36mm8
Celera562,341,657 - 62,368,281 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.58NCBI
Tmem156
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554438,255,676 - 8,298,943 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554438,255,689 - 8,312,634 (+)NCBIChiLan1.0ChiLan1.0
TMEM156
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2339,154,449 - 39,226,569 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,347,063 - 39,419,158 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0433,294,287 - 33,360,117 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1439,149,096 - 39,214,112 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,149,096 - 39,214,112 (-)Ensemblpanpan1.1panPan2
TMEM156
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1373,363,397 - 73,409,729 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl373,362,879 - 73,409,737 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,910,960 - 75,957,077 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0374,137,976 - 74,190,559 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl374,138,032 - 74,190,585 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1373,404,223 - 73,456,744 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,557,034 - 73,603,337 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0373,936,994 - 73,983,141 (+)NCBIUU_Cfam_GSD_1.0
Tmem156
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,553,333 - 39,589,370 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364826,712,289 - 6,744,866 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364826,708,908 - 6,744,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM156
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,289,407 - 30,342,600 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,289,424 - 30,342,633 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2831,769,686 - 31,822,918 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM156
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12711,265,642 - 11,328,919 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2711,265,694 - 11,307,917 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604757,679,389 - 57,763,267 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem156
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248407,443,618 - 7,492,151 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248407,441,785 - 7,492,262 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmem156
187 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:47
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000032273
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat

Markers in Region
AU047388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,233,532 - 43,233,677 (+)MAPPERmRatBN7.2
Rnor_6.01444,899,461 - 44,899,605NCBIRnor6.0
Rnor_5.01444,712,566 - 44,712,710UniSTSRnor5.0
RGSC_v3.41445,935,224 - 45,935,368UniSTSRGSC3.4
Celera1442,377,849 - 42,377,993UniSTS
Cytogenetic Map14p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 19 1
Low 1 6 46 39 39 16 12 30 10
Below cutoff 35 3 2 2 8 9 58 23 11 8

Sequence


RefSeq Acc Id: ENSRNOT00000032273   ⟹   ENSRNOP00000032292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,223,419 - 43,252,449 (+)Ensembl
Rnor_6.0 Ensembl1444,889,402 - 44,918,373 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091312   ⟹   ENSRNOP00000068932
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,223,419 - 43,252,293 (+)Ensembl
Rnor_6.0 Ensembl1444,889,287 - 44,918,343 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104482   ⟹   ENSRNOP00000088538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,223,419 - 43,251,427 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115778   ⟹   ENSRNOP00000077717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,223,419 - 43,242,910 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116225   ⟹   ENSRNOP00000096446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,223,381 - 43,249,981 (+)Ensembl
RefSeq Acc Id: NM_001025138   ⟹   NP_001020309
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,577,050 - 43,606,109 (+)NCBI
mRatBN7.21443,223,394 - 43,252,453 (+)NCBI
Rnor_6.01444,889,402 - 44,918,377 (+)NCBI
Rnor_5.01444,700,605 - 44,731,482 (+)NCBI
RGSC_v3.41445,925,110 - 45,954,140 (+)RGD
Celera1442,367,690 - 42,396,765 (+)RGD
Sequence:
RefSeq Acc Id: NM_001419205   ⟹   NP_001406134
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,577,050 - 43,606,109 (+)NCBI
mRatBN7.21443,223,394 - 43,252,453 (+)NCBI
RefSeq Acc Id: NM_001419206   ⟹   NP_001406135
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,577,050 - 43,606,109 (+)NCBI
mRatBN7.21443,223,394 - 43,252,453 (+)NCBI
RefSeq Acc Id: XM_039092289   ⟹   XP_038948217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,568,196 - 43,605,935 (+)NCBI
mRatBN7.21443,221,464 - 43,251,788 (+)NCBI
RefSeq Acc Id: XM_063273463   ⟹   XP_063129533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,568,131 - 43,605,935 (+)NCBI
RefSeq Acc Id: XM_063273465   ⟹   XP_063129535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,568,196 - 43,596,425 (+)NCBI
RefSeq Acc Id: NP_001020309   ⟸   NM_001025138
- Peptide Label: isoform 3
- UniProtKB: Q5BK38 (UniProtKB/Swiss-Prot),   A0A8I5Y6N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068932   ⟸   ENSRNOT00000091312
RefSeq Acc Id: ENSRNOP00000032292   ⟸   ENSRNOT00000032273
RefSeq Acc Id: XP_038948217   ⟸   XM_039092289
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GH70 (UniProtKB/TrEMBL),   A6JDF5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096446   ⟸   ENSRNOT00000116225
RefSeq Acc Id: ENSRNOP00000077717   ⟸   ENSRNOT00000115778
RefSeq Acc Id: ENSRNOP00000088538   ⟸   ENSRNOT00000104482
RefSeq Acc Id: NP_001406135   ⟸   NM_001419206
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001406134   ⟸   NM_001419205
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JU22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129533   ⟸   XM_063273463
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063129535   ⟸   XM_063273465
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK38-F1-model_v2 AlphaFold Q5BK38 1-286 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699322
Promoter ID:EPDNEW_R9844
Type:single initiation site
Name:Tmem156_1
Description:transmembrane protein 156
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01444,889,378 - 44,889,438EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562424 AgrOrtholog
BioCyc Gene G2FUF-15731 BioCyc
Ensembl Genes ENSRNOG00000026518 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032273 ENTREZGENE
  ENSRNOT00000032273.5 UniProtKB/Swiss-Prot
  ENSRNOT00000091312 ENTREZGENE
  ENSRNOT00000091312.2 UniProtKB/TrEMBL
  ENSRNOT00000104482.1 UniProtKB/TrEMBL
  ENSRNOT00000115778.1 UniProtKB/TrEMBL
  ENSRNOT00000116225.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7384360 IMAGE-MGC_LOAD
InterPro TMEM156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498365 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108944 IMAGE-MGC_LOAD
NCBI Gene 498365 ENTREZGENE
PANTHER PTHR14788 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TMEM156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmem156 PhenoGen
RatGTEx ENSRNOG00000026518 RatGTEx
UniProt A0A0G2JU22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y6N5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQJ6_RAT UniProtKB/TrEMBL
  A0A8I6GH70 ENTREZGENE, UniProtKB/TrEMBL
  A6JDF5 ENTREZGENE, UniProtKB/TrEMBL
  Q5BK38 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Tmem156  transmembrane protein 156  LOC498365  hypothetical protein LOC498365  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498365  hypothetical protein LOC498365      Symbol and Name status set to provisional 70820 PROVISIONAL