Rpl27al3 (ribosomal protein L27A like 3) - Rat Genome Database

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Gene: Rpl27al3 (ribosomal protein L27A like 3) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl27al3
Name: ribosomal protein L27A like 3
RGD ID: 1562402
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL27A (ribosomal protein L27a); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L27a-like; large ribosomal subunit protein uL15-like; LOC499133; RGD1562402; similar to 60S ribosomal protein L27a
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8198,699,829 - 98,700,353 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl641,230,191 - 41,251,349 (-)EnsemblGRCr8
GRCr8 Ensembl198,692,366 - 98,700,693 (+)EnsemblGRCr8
mRatBN7.2189,563,034 - 89,563,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl189,563,034 - 89,563,740 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl114,662,754 - 14,663,684 (-)EnsemblmRatBN7.2
Rnor_6.0193,242,022 - 93,242,530 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl193,242,050 - 93,242,493 (+)Ensemblrn6Rnor6.0
Rnor_5.0194,354,431 - 94,354,944 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4189,339,479 - 89,339,925 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera183,904,462 - 83,904,970 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rpl27al3
3 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:111
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000013741, ENSRNOT00000045301
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
AA900726  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q33UniSTS
Cytogenetic Map11q23UniSTS
MARC_1767-1768:991931306:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2189,563,263 - 89,563,500 (+)MAPPERmRatBN7.2
mRatBN7.21163,541,042 - 163,542,183 (+)MAPPERmRatBN7.2
Rnor_6.01174,134,088 - 174,135,228NCBIRnor6.0
Rnor_6.0193,242,254 - 93,242,490NCBIRnor6.0
Rnor_5.0194,354,654 - 94,354,890UniSTSRnor5.0
Rnor_5.01181,122,758 - 181,123,898UniSTSRnor5.0
RGSC_v3.41167,116,679 - 167,117,819UniSTSRGSC3.4
RGSC_v3.4189,339,683 - 89,339,919UniSTSRGSC3.4
Celera183,904,694 - 83,904,930UniSTS
Celera1161,442,693 - 161,443,833UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map1q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 156 89 88 57 92 57 6 353 192 11 135 81 91 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000013741   ⟹   ENSRNOP00000074375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl641,230,191 - 41,251,349 (-)Ensembl
mRatBN7.2 Ensembl114,662,754 - 14,663,684 (-)Ensembl
Rnor_6.0 Ensembl193,242,050 - 93,242,493 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150027   ⟹   ENSRNOP00000109360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl641,230,257 - 41,251,349 (-)Ensembl
RefSeq Acc Id: XM_039100866   ⟹   XP_038956794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8198,699,829 - 98,700,353 (+)NCBI
mRatBN7.2189,563,034 - 89,563,540 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038956794 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048422.5
  ENSRNOP00000109360.1
Ensembl Acc Id: ENSRNOP00000074375   ⟸   ENSRNOT00000013741
RefSeq Acc Id: XP_038956794   ⟸   XM_039100866
- UniProtKB: D3ZF07 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109360   ⟸   ENSRNOT00000150027

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7W6-F1-model_v2 AlphaFold A0A0G2K7W6 1-148 view protein structure
AF-D3ZF07-F1-model_v2 AlphaFold D3ZF07 1-153 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689980
Promoter ID:EPDNEW_R501
Type:multiple initiation site
Name:RGD1562402_1
Description:similar to 60S ribosomal protein L27a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0193,242,028 - 93,242,088EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562402 AgrOrtholog
BioCyc Gene G2FUF-59956 BioCyc
Ensembl Genes ENSRNOG00000031859 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000040273 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045301.6 UniProtKB/TrEMBL
  ENSRNOT00000150027.1 UniProtKB/TrEMBL
Gene3D-CATH 3.100.10.10 UniProtKB/TrEMBL
InterPro L18e/L15P_sf UniProtKB/TrEMBL
  Ribosomal_L15 UniProtKB/TrEMBL
  Ribosomal_L15_CS UniProtKB/TrEMBL
  Ribosomal_L18e/L15 UniProtKB/TrEMBL
NCBI Gene 499133 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L27A UniProtKB/TrEMBL
  60S RIBOSOMAL PROTEIN L27A UniProtKB/TrEMBL
Pfam Ribosomal_L18e UniProtKB/TrEMBL
PhenoGen Rpl27al3 PhenoGen
PROSITE RIBOSOMAL_L15 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031859 RatGTEx
  ENSRNOG00000040273 RatGTEx
Superfamily-SCOP Ribosomal_L18e/L15 UniProtKB/TrEMBL
UniProt A0ABK0LF68_RAT UniProtKB/TrEMBL
  D3ZF07 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rpl27al3  ribosomal protein L27A like 3  RGD1562402  similar to 60S ribosomal protein L27a  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1562402  similar to 60S ribosomal protein L27a   RGD1562402_predicted  similar to 60S ribosomal protein L27a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562402_predicted  similar to 60S ribosomal protein L27a (predicted)  LOC499133  similar to 60S ribosomal protein L27a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499133  similar to 60S ribosomal protein L27a      Symbol and Name status set to provisional 70820 PROVISIONAL