Mageb16 (MAGE family member B16) - Rat Genome Database

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Gene: Mageb16 (MAGE family member B16) Rattus norvegicus
Analyze
Symbol: Mageb16
Name: MAGE family member B16
RGD ID: 1562365
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEB16 (MAGE family member B16); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC317274; LOC317274; MAGE-B16 antigen; melanoma antigen family B, 16; melanoma-associated antigen B16; Snca
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X47,580,752 - 47,665,173 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX47,580,439 - 47,665,225 (-)EnsemblGRCr8
mRatBN7.2X43,693,205 - 43,725,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX43,693,211 - 43,725,657 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX45,025,398 - 45,055,594 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X48,492,757 - 48,522,955 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X46,157,450 - 46,187,648 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X46,977,655 - 47,026,377 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX46,977,655 - 47,078,128 (-)Ensemblrn6Rnor6.0
Rnor_5.0X47,191,588 - 47,237,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X65,483,955 - 65,512,589 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX44,336,416 - 44,366,444 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Mageb16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X47,580,752 - 47,665,173 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX47,580,439 - 47,665,225 (-)EnsemblGRCr8
mRatBN7.2X43,693,205 - 43,725,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX43,693,211 - 43,725,657 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX45,025,398 - 45,055,594 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X48,492,757 - 48,522,955 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X46,157,450 - 46,187,648 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X46,977,655 - 47,026,377 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX46,977,655 - 47,078,128 (-)Ensemblrn6Rnor6.0
Rnor_5.0X47,191,588 - 47,237,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X65,483,955 - 65,512,589 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX44,336,416 - 44,366,444 (-)NCBICelera
Cytogenetic MapXq21NCBI
MAGEB16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X35,798,342 - 35,803,772 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX35,798,342 - 35,803,772 (+)Ensemblhg38GRCh38
GRCh37X35,816,459 - 35,821,889 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X35,726,380 - 35,731,773 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX39,944,075 - 39,949,468 (+)NCBICelera
Cytogenetic MapXp21.1NCBI
HuRefX33,557,536 - 33,562,929 (+)NCBIHuRef
CHM1_1X35,847,558 - 35,852,951 (+)NCBICHM1_1
T2T-CHM13v2.0X35,394,326 - 35,399,316 (+)NCBIT2T-CHM13v2.0
Mageb16-ps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X143,335,754 - 143,339,235 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX143,338,207 - 143,339,333 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X144,552,758 - 144,556,239 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX144,555,211 - 144,556,337 (-)Ensemblmm10GRCm38
MGSCv37X139,801,546 - 139,802,705 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X140,989,299 - 140,991,135 (-)NCBIMGSCv36mm8
CeleraX128,510,174 - 128,511,333 (-)NCBICelera
Cytogenetic MapXF2NCBI
cM MapX65.69NCBI
Mageb16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554998,159,691 - 8,173,930 (+)NCBIChiLan1.0ChiLan1.0
MAGEB16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X37,643,015 - 37,650,720 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X37,646,531 - 37,654,095 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X28,444,872 - 28,450,693 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X36,078,785 - 36,084,368 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX36,081,171 - 36,083,807 (+)EnsemblpanPan2panpan1.1
LOC100856762
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X30,061,692 - 30,064,909 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX35,054,771 - 35,057,992 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X30,105,002 - 30,108,222 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1X30,161,233 - 30,164,453 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X30,150,856 - 30,154,076 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X30,261,197 - 30,264,417 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100522230
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X31,573,305 - 31,574,593 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X34,994,834 - 34,997,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Mageb16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476219,674,668 - 19,720,676 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Mageb16
463 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:466
Count of miRNA genes:224
Interacting mature miRNAs:260
Transcripts:ENSRNOT00000042568
Prediction methods:Microtar, Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 3 1 3 1 2 9 16 11 3 1 43 2

Sequence


Ensembl Acc Id: ENSRNOT00000042568   ⟹   ENSRNOP00000064565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,634 - 47,665,225 (-)Ensembl
mRatBN7.2 EnsemblX43,693,219 - 43,725,657 (-)Ensembl
Rnor_6.0 EnsemblX46,977,657 - 47,024,102 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092871   ⟹   ENSRNOP00000076053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,757 - 47,610,593 (-)Ensembl
mRatBN7.2 EnsemblX43,693,219 - 43,721,333 (-)Ensembl
Rnor_6.0 EnsemblX46,977,655 - 47,078,128 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116863   ⟹   ENSRNOP00000097562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,716 - 47,596,472 (-)Ensembl
mRatBN7.2 EnsemblX43,693,211 - 43,713,808 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126582   ⟹   ENSRNOP00000103124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,439 - 47,613,132 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161603   ⟹   ENSRNOP00000103351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,439 - 47,613,244 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161652   ⟹   ENSRNOP00000106642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,439 - 47,601,507 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000168719   ⟹   ENSRNOP00000110263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX47,580,439 - 47,613,244 (-)Ensembl
RefSeq Acc Id: NM_001025013   ⟹   NP_001020184
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X47,580,752 - 47,610,936 (-)NCBI
mRatBN7.2X43,693,205 - 43,723,389 (-)NCBI
Rnor_6.0X46,977,655 - 47,024,102 (-)NCBI
Rnor_5.0X47,191,588 - 47,237,657 (-)NCBI
RGSC_v3.4X65,483,955 - 65,512,589 (-)RGD
CeleraX44,336,416 - 44,366,444 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256977   ⟹   XP_006257039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X47,580,758 - 47,613,183 (-)NCBI
mRatBN7.2X43,693,211 - 43,725,625 (-)NCBI
Rnor_6.0X46,977,661 - 47,026,370 (-)NCBI
Rnor_5.0X47,191,588 - 47,237,657 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063280033   ⟹   XP_063136103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X47,580,758 - 47,665,171 (-)NCBI
RefSeq Acc Id: XM_063280034   ⟹   XP_063136104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X47,580,758 - 47,665,173 (-)NCBI
RefSeq Acc Id: XM_063280035   ⟹   XP_063136105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X47,580,758 - 47,665,173 (-)NCBI
RefSeq Acc Id: NP_001020184   ⟸   NM_001025013
- UniProtKB: Q6AY37 (UniProtKB/Swiss-Prot),   M0R5A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257039   ⟸   XM_006256977
- Peptide Label: isoform X1
- UniProtKB: Q6AY37 (UniProtKB/Swiss-Prot),   M0R5A2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000076053   ⟸   ENSRNOT00000092871
Ensembl Acc Id: ENSRNOP00000064565   ⟸   ENSRNOT00000042568
Ensembl Acc Id: ENSRNOP00000097562   ⟸   ENSRNOT00000116863
RefSeq Acc Id: XP_063136104   ⟸   XM_063280034
- Peptide Label: isoform X1
- UniProtKB: Q6AY37 (UniProtKB/Swiss-Prot),   M0R5A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136105   ⟸   XM_063280035
- Peptide Label: isoform X1
- UniProtKB: Q6AY37 (UniProtKB/Swiss-Prot),   M0R5A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136103   ⟸   XM_063280033
- Peptide Label: isoform X1
- UniProtKB: Q6AY37 (UniProtKB/Swiss-Prot),   M0R5A2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110263   ⟸   ENSRNOT00000168719
Ensembl Acc Id: ENSRNOP00000103124   ⟸   ENSRNOT00000126582
Ensembl Acc Id: ENSRNOP00000106642   ⟸   ENSRNOT00000161652
Ensembl Acc Id: ENSRNOP00000103351   ⟸   ENSRNOT00000161603
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY37-F1-model_v2 AlphaFold Q6AY37 1-360 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562365 AgrOrtholog
BioCyc Gene G2FUF-2382 BioCyc
Ensembl Genes ENSRNOG00000029408 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042568 ENTREZGENE
  ENSRNOT00000042568.5 UniProtKB/Swiss-Prot
  ENSRNOT00000092871.2 UniProtKB/Swiss-Prot
  ENSRNOT00000116863 ENTREZGENE
  ENSRNOT00000116863.1 UniProtKB/Swiss-Prot
  ENSRNOT00000161603 ENTREZGENE
  ENSRNOT00000168719 ENTREZGENE
Gene3D-CATH 1.10.10.1200 UniProtKB/Swiss-Prot
  1.10.10.1210 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7131795 IMAGE-MGC_LOAD
InterPro MAGE UniProtKB/Swiss-Prot
  MAGE_WH1 UniProtKB/Swiss-Prot
  MAGE_WH2 UniProtKB/Swiss-Prot
  MHD_dom UniProtKB/Swiss-Prot
KEGG Report rno:317274 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94270 IMAGE-MGC_LOAD
NCBI Gene 317274 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B16 UniProtKB/Swiss-Prot
  PTHR11736 UniProtKB/Swiss-Prot
Pfam MAGE UniProtKB/Swiss-Prot
PhenoGen Mageb16 PhenoGen
PROSITE MAGE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029408 RatGTEx
SMART MAGE UniProtKB/Swiss-Prot
UniProt M0R5A2 ENTREZGENE, UniProtKB/TrEMBL
  MAGBG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Mageb16  MAGE family member B16  Mageb16  melanoma antigen family B, 16  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Mageb16  melanoma antigen family B, 16  LOC317274  hypothetical protein LOC317274  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC317274  hypothetical protein LOC317274      Symbol and Name status set to provisional 70820 PROVISIONAL