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Gene: Foxn2 (forkhead box N2) Rattus norvegicus

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Symbol:

Foxn2

Name:

forkhead box N2

RGD ID:

1562291

Description:

Predicted to enable DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within skeletal muscle cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human FOXN2 (forkhead box N2); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

forkhead box protein N2; LOC301676; RGD1562291; similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FOXN2 (forkhead box N2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Foxn2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Foxn2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FOXN2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FOXN2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Foxn2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FOXN2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FOXN2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Foxn2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Foxn2 (forkhead box N2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FOXN2 (forkhead box N2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Foxn2 (forkhead box N2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	foxn2a (forkhead box N2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	foxn2a (forkhead box N2a)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	foxn2b (forkhead box N2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CHES-1-like	Alliance	DIOPT (OrthoFinder\|OrthoInspector)
Xenopus tropicalis (tropical clawed frog):	foxn2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	11,772,180 - 11,818,751 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	11,772,180 - 11,818,751 (-)	Ensembl				GRCr8
mRatBN7.2	6	6,018,653 - 6,065,226 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	6,018,879 - 6,064,278 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	6,302,257 - 6,356,285 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	6,611,631 - 6,665,664 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	6,138,796 - 6,192,827 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	12,158,127 - 12,205,450 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	12,179,227 - 12,205,446 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	22,124,363 - 22,170,775 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	12,267,384 - 12,278,896 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	5,788,949 - 5,835,379 (-)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

gentamycin (EXP)

indometacin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

rac-lactic acid (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

regulation of DNA-templated transcription (IBA,IEA)

skeletal muscle cell differentiation (ISO)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA)

Molecular Function

cis-regulatory region sequence-specific DNA binding (IBA)

DNA binding (IEA)

DNA-binding transcription factor activity (IBA,IEA)

protein binding (ISO)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22147266

Genomics

Comparative Map Data

Foxn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	11,772,180 - 11,818,751 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	11,772,180 - 11,818,751 (-)	Ensembl				GRCr8
mRatBN7.2	6	6,018,653 - 6,065,226 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	6,018,879 - 6,064,278 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	6,302,257 - 6,356,285 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	6,611,631 - 6,665,664 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	6,138,796 - 6,192,827 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	12,158,127 - 12,205,450 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	12,179,227 - 12,205,446 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	22,124,363 - 22,170,775 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	12,267,384 - 12,278,896 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	5,788,949 - 5,835,379 (-)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

FOXN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	48,313,659 - 48,379,295 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	48,314,331 - 48,379,295 (+)	Ensembl			hg38	GRCh38
GRCh37	2	48,541,438 - 48,606,434 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	48,395,299 - 48,459,938 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	48,453,520 - 48,518,085	NCBI
Celera	2	48,381,574 - 48,446,198 (+)	NCBI		Celera
Cytogenetic Map	2	p16.3	NCBI
HuRef	2	48,277,701 - 48,342,337 (+)	NCBI		HuRef
CHM1_1	2	48,471,985 - 48,536,626 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	48,320,267 - 48,385,262 (+)	NCBI		T2T-CHM13v2.0

Foxn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	88,746,430 - 88,797,961 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	88,748,139 - 88,797,961 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	88,440,704 - 88,490,533 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	88,440,711 - 88,490,533 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	88,840,052 - 88,889,873 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	88,349,084 - 88,386,397 (+)	NCBI		MGSCv36	mm8
Celera	17	92,856,967 - 92,909,156 (+)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI
cM Map	17	57.97	NCBI

Foxn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	14,882,291 - 14,950,878 (+)	Ensembl
ChiLan1.0	NW_004955441	14,882,312 - 14,950,878 (+)	NCBI	ChiLan1.0	ChiLan1.0

FOXN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	77,998,142 - 78,063,087 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	78,002,110 - 78,067,466 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	48,441,683 - 48,506,631 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	49,363,949 - 49,428,502 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	49,364,147 - 49,428,502 (+)	Ensembl			panPan2	panpan1.1

FOXN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	50,225,559 - 50,291,817 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	50,259,940 - 50,288,901 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	50,079,564 - 50,145,522 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	51,104,933 - 51,171,390 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	51,105,241 - 51,171,388 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	50,804,787 - 50,871,099 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	51,092,229 - 51,158,350 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	51,280,162 - 51,346,387 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Foxn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	32,804,966 - 32,855,243 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936508	4,233,574 - 4,283,971 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936508	4,233,575 - 4,283,845 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FOXN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	92,268,787 - 92,336,857 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	92,268,780 - 92,337,117 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	98,079,373 - 98,147,147 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FOXN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	58,783,009 - 58,848,672 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	58,782,897 - 58,835,451 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	53,002,492 - 53,068,166 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Foxn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	29,538,123 - 29,609,618 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	29,538,099 - 29,609,214 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Foxn2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	4,404,204 - 4,448,257 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Foxn2
431 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	38
Count of miRNA genes:	36
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000061693
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	1	25740059	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	20510098	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat

Markers in Region

D6Rat213

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	6	11,872,966 - 11,873,063 (+)	Marker Load Pipeline
mRatBN7.2	6	6,119,373 - 6,119,470 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	12,104,119 - 12,104,215	NCBI	Rnor6.0
Rnor_5.0	6	22,072,861 - 22,072,957	UniSTS	Rnor5.0
RGSC_v3.4	6	12,019,226 - 12,019,322	UniSTS	RGSC3.4
RGSC_v3.4	6	12,019,225 - 12,019,322	RGD	RGSC3.4
Celera	6	5,887,672 - 5,887,768	UniSTS
RGSC_v3.1	6	12,019,225 - 12,019,322	RGD
SHRSP x BN Map	6	0.0	UniSTS
SHRSP x BN Map	6	0.0	RGD
Cytogenetic Map	6	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_237502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000061693 ⟹ ENSRNOP00000058404

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	11,772,180 - 11,818,751 (-)	Ensembl
mRatBN7.2 Ensembl	6	6,018,879 - 6,064,278 (-)	Ensembl
Rnor_6.0 Ensembl	6	12,179,227 - 12,205,446 (+)	Ensembl

RefSeq Acc Id:

NM_001399771 ⟹ NP_001386700

RefSeq Status:

INFERRED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,818,751 (-)	NCBI
mRatBN7.2	6	6,018,653 - 6,065,226 (-)	NCBI

RefSeq Acc Id:

XM_006239738 ⟹ XP_006239800

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,818,520 (-)	NCBI
mRatBN7.2	6	6,018,885 - 6,064,991 (-)	NCBI
Rnor_6.0	6	12,158,466 - 12,202,220 (+)	NCBI
Rnor_5.0	6	22,124,363 - 22,170,775 (+)	NCBI

Sequence:

show sequence

TCAGGCGAGCCCACGCTCCTGGGGGTGTGGAACCGAGGCGGGCACGGCCCCGTGAGGAGTTAGG
AGTTTCTCCTGAGAAATATAGGAGTAAATGGGTCCAGTAATTGGAATGACTCCGGATAAGAGAG
CTGAGACCCCGGGAGCTGAGAAGGTTGCAGGACTGAGTCAGATTTACAAAATGGGGAGTTTGCC
TGAAGCTGGGGAAGCTTCCAGGCCAAAGGCCACTCTAGTGGGCAGTGACTCCACAGATGACGAA
CTAACAAACTTGAACTGGCTTCATGAGAGTAGTGACCTTCTAACCAACCTCAGGCTCGGCGGTG
AAGGCCTTCCAATGGTTAGCCCATTGTATGACATAGAGGGAGATGATATGCCATCCTTTGGACC
ATTGTGCTGCCAGAACCCAGAAAAGAAGTCAGCAACTTCCAAGCCCCCCTACTCCTTTAGTCTT
CTCATTTACATGGCCATCGAACACTCGCCAAATAAGTGCTTGCCTGTCAAAGAGATTTACAGCT
GGATCCTGGATCGCTTCCCGTACTTTGCCACTGCACCTACAGGCTGGAAGAATTCTGTTCGGCA
TAATCTATCCCTGAATAAATGTTTTCAGAAAGTGGAAAGAAGTCACGGCAAGGTTAATGGAAAA
GGCTCCTTATGGTGCGTTGATCCAGAATATAAGCCCAATCTTGTGCAGGCCTTGAAGAAGCAAC
CGTTTTCCTCTCCACAAAGTGCTTCTTTATCGCCTCACTACTTAAGCTCTGTTCTCAAGCAAAG
TCAAGTGCAAACTCTTAAAGAATCTGATATTGATGCTGCCACTGCAATGATACTTTTAAATACT
TCAATAGAACAAGAGATGTTAGAGTGTGAGAAGCCTCTGCCTCTTAAAACATCACTGCAGAAAA
AGAGGAGTTACGGCAGCGCGTTCAGTGCCCCCAGTGCTGTGCAACTGCAGGAGAGCCATTCTCC
AGCCTCCAGCATCGACCCAAAAGCAGACCATAACTACAGTGCCAGCGGCGTGGCAGCCCAGCGT
TGTGCATCGAGGGCTAGCATGTCTTCCCTGTCTTCTGTGGATGAGGTGTATGAATTCATCCCCA
AGAGTAGCCATGGCGGGAGTGACGGCAGCGAAGGCTTCCACAGTGACGAGGAGACAGATGCTGA
GGATGAGGATCCTCTTGCAGACAGTGGCTATGCACCGCAAGCTCTTGAAGACAGCACTCGGAAA
GGACAGCCAGGCCAAAAGATTCCAAAACAGTCATGTCAAGAGATCGATGAGGAGCTCAAAGAAG
CAGCCGGGTCGCTGCTCCACCTTGCTGGAATCCGCACCTGCCTTGGCTCCCTTATAAGTACTGC
AAAGGCACAAAGTCAAAAACACCGGAAAAAGTAGAAATGCTTATAGTGTGGAGTTGTTTTAAAG
TGTGGCAATACTCTTCTACTTAACTTTTTACCAGGGATACAGAGCCATATCAGATGGACCGCTT
TAGCTAAGGGTGGGGGAGGCGTGCCACTTGTTTCTTTCTAAATATTTTTTGGTTGCTTTTCTTT
TTTGTTTAAACAGTTGCTCTTAGGATCATGCATAATTGTAAATCTGACATAAAGGACCCCACAA
CATAATT

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RefSeq Acc Id:

XM_039113051 ⟹ XP_038968979

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,817,324 (-)	NCBI
mRatBN7.2	6	6,018,885 - 6,063,795 (-)	NCBI

RefSeq Acc Id:

XM_039113052 ⟹ XP_038968980

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,802,349 (-)	NCBI
mRatBN7.2	6	6,018,885 - 6,048,467 (-)	NCBI

RefSeq Acc Id:

XM_039113053 ⟹ XP_038968981

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,817,547 (-)	NCBI
mRatBN7.2	6	6,018,885 - 6,064,026 (-)	NCBI

RefSeq Acc Id:

XM_237502 ⟹ XP_237502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	11,772,180 - 11,817,802 (-)	NCBI
mRatBN7.2	6	6,018,885 - 6,064,678 (-)	NCBI
Rnor_6.0	6	12,159,269 - 12,202,220 (+)	NCBI
Rnor_5.0	6	22,124,363 - 22,170,775 (+)	NCBI
RGSC_v3.4	6	12,267,384 - 12,278,896 (+)	RGD

Sequence:

show sequence

GAGGAGGAGTCATAAGTGCAGAGAAATGACAGACTTTTTTTTTTCCTACTTGCAACTCCGCCGC
GAGCGGTTAATTATTTCCAGAAATATAGGAGTAAATGGGTCCAGTAATTGGAATGACTCCGGAT
AAGAGAGCTGAGACCCCGGGAGCTGAGAAGGTTGCAGGACTGAGTCAGATTTACAAAATGGGGA
GTTTGCCTGAAGCTGGGGAAGCTTCCAGGCCAAAGGCCACTCTAGTGGGCAGTGACTCCACAGA
TGACGAACTAACAAACTTGAACTGGCTTCATGAGAGTAGTGACCTTCTAACCAACCTCAGGCTC
GGCGGTGAAGGCCTTCCAATGGTTAGCCCATTGTATGACATAGAGGGAGATGATATGCCATCCT
TTGGACCATTGTGCTGCCAGAACCCAGAAAAGAAGTCAGCAACTTCCAAGCCCCCCTACTCCTT
TAGTCTTCTCATTTACATGGCCATCGAACACTCGCCAAATAAGTGCTTGCCTGTCAAAGAGATT
TACAGCTGGATCCTGGATCGCTTCCCGTACTTTGCCACTGCACCTACAGGCTGGAAGAATTCTG
TTCGGCATAATCTATCCCTGAATAAATGTTTTCAGAAAGTGGAAAGAAGTCACGGCAAGGTTAA
TGGAAAAGGCTCCTTATGGTGCGTTGATCCAGAATATAAGCCCAATCTTGTGCAGGCCTTGAAG
AAGCAACCGTTTTCCTCTCCACAAAGTGCTTCTTTATCGCCTCACTACTTAAGCTCTGTTCTCA
AGCAAAGTCAAGTGCAAACTCTTAAAGAATCTGATATTGATGCTGCCACTGCAATGATACTTTT
AAATACTTCAATAGAACAAGAGATGTTAGAGTGTGAGAAGCCTCTGCCTCTTAAAACATCACTG
CAGAAAAAGAGGAGTTACGGCAGCGCGTTCAGTGCCCCCAGTGCTGTGCAACTGCAGGAGAGCC
ATTCTCCAGCCTCCAGCATCGACCCAAAAGCAGACCATAACTACAGTGCCAGCGGCGTGGCAGC
CCAGCGTTGTGCATCGAGGGCTAGCATGTCTTCCCTGTCTTCTGTGGATGAGGTGTATGAATTC
ATCCCCAAGAGTAGCCATGGCGGGAGTGACGGCAGCGAAGGCTTCCACAGTGACGAGGAGACAG
ATGCTGAGGATGAGGATCCTCTTGCAGACAGTGGCTATGCACCGCAAGCTCTTGAAGACAGCAC
TCGGAAAGGACAGCCAGGCCAAAAGATTCCAAAACAGTCATGTCAAGAGATCGATGAGGAGCTC
AAAGAAGCAGCCGGGTCGCTGCTCCACCTTGCTGGAATCCGCACCTGCCTTGGCTCCCTTATAA
GTACTGCAAAGGCACAAAGTCAAAAACACCGGAAAAAGTAGAAATGCTTATAGTGTGGAGTTGT
TTTAAAGTGTGGCAATACTCTTCTACTTAACTTTTTACCAGGGATACAGAGCCATATCAGATGG
ACCGCTTTAGCTAAGGGTGGGGGAGGCGTGCCACTTGTTTCTTTCTAAATATTTTTTGGTTGCT
TTTCTTTTTTGTTTAAACAGTTGCTCTTAGGATCATGCATAATTGTAAATCTGACATAAAGGAC
CCCACAACATAATT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001386700	(Get FASTA)	NCBI Sequence Viewer
	XP_006239800	(Get FASTA)	NCBI Sequence Viewer
	XP_038968979	(Get FASTA)	NCBI Sequence Viewer
	XP_038968980	(Get FASTA)	NCBI Sequence Viewer
	XP_038968981	(Get FASTA)	NCBI Sequence Viewer
	XP_237502	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000058404
	ENSRNOP00000058404.3

RefSeq Acc Id:	XP_237502 ⟸ XM_237502
- Peptide Label:	isoform X1
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPVIGMTPDKRAETPGAEKVAGLSQIYKMGSLPEAGEASRPKATLVGSDSTDDELTNLNWLHE SSDLLTNLRLGGEGLPMVSPLYDIEGDDMPSFGPLCCQNPEKKSATSKPPYSFSLLIYMAIEHS PNKCLPVKEIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPE YKPNLVQALKKQPFSSPQSASLSPHYLSSVLKQSQVQTLKESDIDAATAMILLNTSIEQEMLEC EKPLPLKTSLQKKRSYGSAFSAPSAVQLQESHSPASSIDPKADHNYSASGVAAQRCASRASMSS LSSVDEVYEFIPKSSHGGSDGSEGFHSDEETDAEDEDPLADSGYAPQALEDSTRKGQPGQKIPK QSCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKAQSQKHRKK hide sequence

RefSeq Acc Id:	XP_006239800 ⟸ XM_006239738
- Peptide Label:	isoform X1
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPVIGMTPDKRAETPGAEKVAGLSQIYKMGSLPEAGEASRPKATLVGSDSTDDELTNLNWLHE SSDLLTNLRLGGEGLPMVSPLYDIEGDDMPSFGPLCCQNPEKKSATSKPPYSFSLLIYMAIEHS PNKCLPVKEIYSWILDRFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDPE YKPNLVQALKKQPFSSPQSASLSPHYLSSVLKQSQVQTLKESDIDAATAMILLNTSIEQEMLEC EKPLPLKTSLQKKRSYGSAFSAPSAVQLQESHSPASSIDPKADHNYSASGVAAQRCASRASMSS LSSVDEVYEFIPKSSHGGSDGSEGFHSDEETDAEDEDPLADSGYAPQALEDSTRKGQPGQKIPK QSCQEIDEELKEAAGSLLHLAGIRTCLGSLISTAKAQSQKHRKK hide sequence

Ensembl Acc Id:

ENSRNOP00000058404 ⟸ ENSRNOT00000061693

RefSeq Acc Id:	XP_038968981 ⟸ XM_039113053
- Peptide Label:	isoform X1
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968979 ⟸ XM_039113051
- Peptide Label:	isoform X1
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968980 ⟸ XM_039113052
- Peptide Label:	isoform X1
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386700 ⟸ NM_001399771
- UniProtKB:	F1LZM0 (UniProtKB/TrEMBL)

Protein Domains

Fork-head

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LZM0-F1-model_v2	AlphaFold	F1LZM0	1-428	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562291	AgrOrtholog
BioCyc Gene	G2FUF-38764	BioCyc
Ensembl Genes	ENSRNOG00000040110	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000061693	ENTREZGENE
	ENSRNOT00000061693.6	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
InterPro	FH_FOXN2	UniProtKB/TrEMBL
	FOXN2-4-like	UniProtKB/TrEMBL
	TF_fork_head	UniProtKB/TrEMBL
	TF_fork_head_CS	UniProtKB/TrEMBL
	TF_fork_head_CS_2	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	301676	ENTREZGENE
PANTHER	FORKHEAD BOX PROTEIN N2	UniProtKB/TrEMBL
	FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED	UniProtKB/TrEMBL
Pfam	Fork_head	UniProtKB/TrEMBL
PhenoGen	Foxn2	PhenoGen
PRINTS	FORKHEAD	UniProtKB/TrEMBL
PROSITE	FORK_HEAD_1	UniProtKB/TrEMBL
	FORK_HEAD_2	UniProtKB/TrEMBL
	FORK_HEAD_3	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000040110	RatGTEx
SMART	SM00339	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
UniProt	F1LZM0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-11	Foxn2	forkhead box N2	RGD1562291	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1562291	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)	RGD1562291_predicted	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2) (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1562291_predicted	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2) (predicted)	LOC301676	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC301676	similar to Human T-cell leukemia virus enhancer factor (Forkhead box protein N2)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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