Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Map3k9 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Map3k9 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of MAP3K9 mRNA | CTD | PMID:22206623 | Map3k9 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of MAP3K9 mRNA | CTD | PMID:29097150 | Map3k9 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MAP3K9 mRNA | CTD | PMID:30851411 | Map3k9 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Map3k9 (Mus musculus) | 6480464 | bisphenol S affects the methylation of MAP3K9 gene | CTD | PMID:31683443 | Map3k9 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MAP3K9 mRNA | CTD | PMID:24780913 | Map3k9 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of MAP3K9 mRNA | CTD | PMID:31881176 | Map3k9 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of MAP3K9 mRNA | CTD | PMID:28959563 | Map3k9 | Rat | aristolochic acid A | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of MAP3K9 mRNA | CTD | PMID:33212167 | Map3k9 | Rat | benzo[a]pyrene | increases methylation | ISO | MAP3K9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MAP3K9 3' UTR | CTD | PMID:27901495 | Map3k9 | Rat | benzo[a]pyrene | decreases methylation | ISO | MAP3K9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MAP3K9 promoter | CTD | PMID:27901495 | Map3k9 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MAP3K9 mRNA | CTD | PMID:25181051|PMID:32145629 | Map3k9 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MAP3K9 mRNA | CTD | PMID:29097150|PMID:30816183|PMID:34947998 | Map3k9 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MAP3K9 gene | CTD | PMID:28505145 | Map3k9 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of MAP3K9 mRNA | CTD | PMID:32479839 | Map3k9 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Map3k9 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of MAP3K9 3' UTR | CTD | PMID:28392331 | Map3k9 | Rat | cadmium dichloride | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of MAP3K9 mRNA | CTD | PMID:38174414|PMID:38568856 | Map3k9 | Rat | caffeine | increases phosphorylation | ISO | MAP3K9 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of MAP3K9 protein | CTD | PMID:35688186 | Map3k9 | Rat | crocidolite asbestos | affects expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Asbestos, Crocidolite affects the expression of MAP3K9 mRNA | CTD | PMID:17331233 | Map3k9 | Rat | cyclosporin A | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MAP3K9 mRNA | CTD | PMID:25562108 | Map3k9 | Rat | Dibutyl phosphate | affects expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MAP3K9 mRNA | CTD | PMID:37042841 | Map3k9 | Rat | dicrotophos | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of MAP3K9 mRNA | CTD | PMID:28302478 | Map3k9 | Rat | dimethylarsinic acid | multiple interactions | ISO | Map3k9 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Map3k9 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression more ... | CTD | PMID:33729688 | Map3k9 | Rat | dorsomorphin | multiple interactions | ISO | MAP3K9 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Map3k9 | Rat | doxorubicin | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MAP3K9 mRNA | CTD | PMID:29803840 | Map3k9 | Rat | epoxiconazole | increases expression | ISO | Map3k9 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of MAP3K9 mRNA | CTD | PMID:35436446 | Map3k9 | Rat | Erionite | decreases expression | ISO | Map3k9 (Mus musculus) | 6480464 | erionite results in decreased expression of MAP3K9 mRNA | CTD | PMID:29279043 | Map3k9 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of MAP3K9 mRNA | CTD | PMID:30307764 | Map3k9 | Rat | folic acid | decreases expression | ISO | Map3k9 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of MAP3K9 mRNA | CTD | PMID:25629700 | Map3k9 | Rat | formaldehyde | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of MAP3K9 mRNA | CTD | PMID:20655997 | Map3k9 | Rat | genistein | increases expression | ISO | Map3k9 (Mus musculus) | 6480464 | Genistein results in increased expression of MAP3K9 mRNA | CTD | PMID:32186404 | Map3k9 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MAP3K9 mRNA | CTD | PMID:33387578 | Map3k9 | Rat | methotrexate | affects expression | ISO | Map3k9 (Mus musculus) | 6480464 | Methotrexate affects the expression of MAP3K9 mRNA | CTD | PMID:18502557 | Map3k9 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of MAP3K9 gene | CTD | PMID:35440735 | Map3k9 | Rat | methylarsonic acid | multiple interactions | ISO | Map3k9 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Map3k9 | Rat | methylparaben | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | methylparaben results in increased expression of MAP3K9 mRNA | CTD | PMID:38568856 | Map3k9 | Rat | okadaic acid | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of MAP3K9 mRNA | CTD | PMID:38832940 | Map3k9 | Rat | ozone | multiple interactions | ISO | Map3k9 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Map3k9 | Rat | paracetamol | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MAP3K9 mRNA | CTD | PMID:29067470 | Map3k9 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MAP3K9 mRNA | CTD | PMID:33387578 | Map3k9 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of MAP3K9 mRNA | CTD | PMID:32680482 | Map3k9 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in increased expression of MAP3K9 mRNA | CTD | PMID:25812627 | Map3k9 | Rat | perfluorooctanoic acid | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of MAP3K9 mRNA | CTD | PMID:25812627 | Map3k9 | Rat | quercetin | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Quercetin results in increased expression of MAP3K9 mRNA | CTD | PMID:21632981 | Map3k9 | Rat | rac-lactic acid | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of MAP3K9 mRNA | CTD | PMID:30851411 | Map3k9 | Rat | SB 431542 | multiple interactions | ISO | MAP3K9 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Map3k9 | Rat | sodium arsenate | multiple interactions | ISO | Map3k9 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Map3k9 | Rat | sodium arsenite | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MAP3K9 mRNA | CTD | PMID:38568856 | Map3k9 | Rat | sodium arsenite | multiple interactions | ISO | Map3k9 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Map3k9 | Rat | sodium arsenite | decreases expression | ISO | Map3k9 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MAP3K9 mRNA | CTD | PMID:37682722 | Map3k9 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of MAP3K9 mRNA | CTD | PMID:19281266 | Map3k9 | Rat | sunitinib | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of MAP3K9 mRNA | CTD | PMID:31533062 | Map3k9 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MAP3K9 mRNA | CTD | PMID:23411599 | Map3k9 | Rat | thiram | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Thiram results in increased expression of MAP3K9 mRNA | CTD | PMID:38568856 | Map3k9 | Rat | titanium dioxide | decreases methylation | ISO | Map3k9 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MAP3K9 gene | CTD | PMID:35295148 | Map3k9 | Rat | titanium dioxide | affects expression | ISO | Map3k9 (Mus musculus) | 6480464 | titanium dioxide affects the expression of MAP3K9 mRNA | CTD | PMID:35295148 | Map3k9 | Rat | trichostatin A | decreases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of MAP3K9 mRNA | CTD | PMID:24935251|PMID:26272509 | Map3k9 | Rat | trichostatin A | multiple interactions | ISO | MAP3K9 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Map3k9 | Rat | triphenyl phosphate | affects expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MAP3K9 mRNA | CTD | PMID:37042841 | Map3k9 | Rat | urethane | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Urethane results in increased expression of MAP3K9 mRNA | CTD | PMID:28818685 | Map3k9 | Rat | valproic acid | increases expression | ISO | Map3k9 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of MAP3K9 mRNA | CTD | PMID:21427059 | Map3k9 | Rat | valproic acid | increases expression | ISO | MAP3K9 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MAP3K9 mRNA | CTD | PMID:23179753 | | 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