Sh3bgrl4 (SH3 domain binding glutamate-rich protein like 4) - Rat Genome Database

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Pathways
Gene: Sh3bgrl4 (SH3 domain binding glutamate-rich protein like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Sh3bgrl4
Name: SH3 domain binding glutamate-rich protein like 4
RGD ID: 1562039
Description: Predicted to be involved in cytoskeleton organization. Predicted to be active in cytosol; INTERACTS WITH bisphenol A.
Type: protein-coding (Ensembl: lncRNA)
RefSeq Status: MODEL
Previously known as: LOC367869; RGD1562039; SH3 domain-binding glutamic acid-rich-like protein 3; similar to MGC82337 protein
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X78,372,727 - 78,387,632 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX78,372,255 - 78,387,636 (-)EnsemblGRCr8
mRatBN7.2X74,292,875 - 74,307,793 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX74,292,911 - 74,307,759 (-)EnsemblmRatBN7.2
Rnor_6.0X80,338,820 - 80,354,928 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX80,341,255 - 80,354,604 (-)Ensemblrn6Rnor6.0
Rnor_5.0X80,517,914 - 80,533,584 (-)NCBIRnor_5.0Rnor_5.0rn5
CeleraX75,563,331 - 75,579,918 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Sh3bgrl4
50 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:66
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000049790
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1 8 2 8 84 43 45 17 50 17 4 110 74 1 72 10 43 28 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000049790   ⟹   ENSRNOP00000042931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX78,372,721 - 78,387,636 (-)Ensembl
mRatBN7.2 EnsemblX74,292,911 - 74,307,759 (-)Ensembl
Rnor_6.0 EnsemblX80,341,255 - 80,354,604 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX78,372,721 - 78,387,636 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000126665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX78,372,255 - 78,387,636 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX78,372,255 - 78,387,636 (-)Ensembl
RefSeq Acc Id: XM_039100402   ⟹   XP_038956330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X78,372,727 - 78,387,632 (-)NCBI
mRatBN7.2X74,292,875 - 74,307,793 (-)NCBI
RefSeq Acc Id: XR_005498354
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X78,372,727 - 78,387,632 (-)NCBI
mRatBN7.2X74,292,875 - 74,307,789 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038956330 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000042931   ⟸   ENSRNOT00000049790
RefSeq Acc Id: XP_038956330   ⟸   XM_039100402
- UniProtKB: D3ZSE1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSE1-F1-model_v2 AlphaFold D3ZSE1 1-97 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562039 AgrOrtholog
BioCyc Gene G2FUF-1874 BioCyc
Ensembl Genes ENSRNOG00000030519 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000126665 ENTREZGENE
  ENSRNOT00000139246 ENTREZGENE
NCBI Gene 367869 ENTREZGENE
PhenoGen Sh3bgrl4 PhenoGen
RatGTEx ENSRNOG00000030519 RatGTEx
UniProt D3ZSE1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Sh3bgrl4  SH3 domain binding glutamate-rich protein like 4  RGD1562039  similar to MGC82337 protein  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1562039  similar to MGC82337 protein   RGD1562039_predicted  similar to MGC82337 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562039_predicted  similar to MGC82337 protein (predicted)  LOC367869  similar to MGC82337 protein  Symbol and Name status set to approved 1299863 APPROVED