Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Surf4 | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Surf4 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of SURF4 mRNA | CTD | PMID:22206623 | Surf4 | Rat | 17beta-estradiol | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of SURF4 mRNA | CTD | PMID:16705744 | Surf4 | Rat | 17beta-estradiol | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Estradiol results in increased expression of SURF4 mRNA | CTD | PMID:39298647 | Surf4 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of SURF4 mRNA | CTD | PMID:29581250 | Surf4 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SURF4 protein | CTD | PMID:31675489 | Surf4 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of SURF4 mRNA | CTD | PMID:31388691 | Surf4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Surf4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SURF4 mRNA | CTD | PMID:21570461 | Surf4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SURF4 mRNA | CTD | PMID:34747641 | Surf4 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | 2,4,6-tribromophenol results in decreased expression of SURF4 mRNA | CTD | PMID:31675489 | Surf4 | Rat | 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of SURF4 mRNA | CTD | PMID:21346803 | Surf4 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of SURF4 mRNA | CTD | PMID:21346803 | Surf4 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of SURF4 protein | CTD | PMID:31675489 | Surf4 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Surf4 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of SURF4 mRNA | CTD | PMID:18648102 | Surf4 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SURF4 mRNA | CTD | PMID:39298647 | Surf4 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SURF4 mRNA | CTD | PMID:28973697 | Surf4 | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SURF4 mRNA | CTD | PMID:30047161 | Surf4 | Rat | aflatoxin B1 | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of SURF4 mRNA | CTD | PMID:19770486 | Surf4 | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SURF4 mRNA | CTD | PMID:16483693 | Surf4 | Rat | arsane | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | arsenic atom | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | benzene | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Benzene results in increased expression of SURF4 mRNA | CTD | PMID:19162166 | Surf4 | Rat | benzo[a]pyrene | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SURF4 mRNA | CTD | PMID:22228805 | Surf4 | Rat | beta-lapachone | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of SURF4 mRNA | CTD | PMID:38218311 | Surf4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SURF4 mRNA | CTD | PMID:25181051 | Surf4 | Rat | bisphenol A | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SURF4 protein | CTD | PMID:33376534|PMID:37567409 | Surf4 | Rat | bisphenol A | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SURF4 mRNA | CTD | PMID:33221593 | Surf4 | Rat | Bisphenol B | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SURF4 protein | CTD | PMID:34186270 | Surf4 | Rat | bisphenol F | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Surf4 | Rat | cadmium atom | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SURF4 more ... | CTD | PMID:35301059 | Surf4 | Rat | cadmium dichloride | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SURF4 more ... | CTD | PMID:35301059 | Surf4 | Rat | carbon nanotube | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of SURF4 mRNA | CTD | PMID:25554681|PMID:25620056 | Surf4 | Rat | CGP 52608 | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SURF4 gene] | CTD | PMID:28238834 | Surf4 | Rat | chloropicrin | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of SURF4 mRNA | CTD | PMID:26352163 | Surf4 | Rat | clobetasol | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Clobetasol results in increased expression of SURF4 mRNA | CTD | PMID:27462272 | Surf4 | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | clofibrate | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of SURF4 mRNA | CTD | PMID:17585979 | Surf4 | Rat | cyclosporin A | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SURF4 mRNA | CTD | PMID:20106945 | Surf4 | Rat | cyclosporin A | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of SURF4 mRNA | CTD | PMID:25270620 | Surf4 | Rat | cytarabine | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of SURF4 mRNA | CTD | PMID:21198554 | Surf4 | Rat | decabromodiphenyl ether | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of SURF4 protein | CTD | PMID:31675489 | Surf4 | Rat | dexamethasone | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Surf4 | Rat | Dibutyl phosphate | affects expression | ISO | SURF4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of SURF4 mRNA | CTD | PMID:37042841 | Surf4 | Rat | dibutyl phthalate | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SURF4 mRNA | CTD | PMID:17361019|PMID:21266533 | Surf4 | Rat | doxorubicin | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SURF4 mRNA | CTD | PMID:29803840 | Surf4 | Rat | fenthion | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SURF4 mRNA | CTD | PMID:34813904 | Surf4 | Rat | folic acid | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of SURF4 mRNA | CTD | PMID:21867686 | Surf4 | Rat | genistein | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Genistein results in decreased expression of SURF4 mRNA | CTD | PMID:16705744 | Surf4 | Rat | indometacin | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Surf4 | Rat | isoflurane | decreases methylation | ISO | Surf4 (Mus musculus) | 6480464 | Isoflurane results in decreased methylation of SURF4 mRNA | CTD | PMID:35249202 | Surf4 | Rat | ivermectin | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SURF4 protein | CTD | PMID:32959892 | Surf4 | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | manganese atom | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | manganese(0) | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | manganese(II) chloride | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SURF4 mRNA | CTD | PMID:30047161 | Surf4 | Rat | nitrates | multiple interactions | ISO | Surf4 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of SURF4 more ... | CTD | PMID:35964746 | Surf4 | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | paracetamol | affects expression | ISO | Surf4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SURF4 mRNA | CTD | PMID:17562736 | Surf4 | Rat | phenobarbital | affects expression | ISO | Surf4 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SURF4 mRNA | CTD | PMID:23091169 | Surf4 | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | resveratrol | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | resveratrol results in increased expression of SURF4 protein | CTD | PMID:25505154 | Surf4 | Rat | sodium arsenate | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | sodium arsenate results in increased expression of SURF4 protein | CTD | PMID:38348393 | Surf4 | Rat | sodium arsenite | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SURF4 mRNA | CTD | PMID:38568856 | Surf4 | Rat | sodium arsenite | decreases expression | ISO | SURF4 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SURF4 protein | CTD | PMID:38228842 | Surf4 | Rat | sodium arsenite | multiple interactions | ISO | SURF4 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Surf4 | Rat | sodium fluoride | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of SURF4 protein | CTD | PMID:28918527 | Surf4 | Rat | sodium fluoride | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of SURF4 protein | CTD | PMID:27548804 | Surf4 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of SURF4 mRNA | CTD | PMID:19281266 | Surf4 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SURF4 mRNA | CTD | PMID:30047161 | Surf4 | Rat | testosterone | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Testosterone deficiency results in decreased expression of SURF4 mRNA | CTD | PMID:33848595 | Surf4 | Rat | tetrachloromethane | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SURF4 mRNA | CTD | PMID:31919559 | Surf4 | Rat | thapsigargin | decreases expression | ISO | Surf4 (Mus musculus) | 6480464 | Thapsigargin results in decreased expression of SURF4 protein | CTD | PMID:24648495 | Surf4 | Rat | thapsigargin | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of SURF4 mRNA | CTD | PMID:22378314 | Surf4 | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of SURF4 mRNA | CTD | PMID:19483382 | Surf4 | Rat | titanium dioxide | increases expression | ISO | Surf4 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SURF4 mRNA | CTD | PMID:27760801 | Surf4 | Rat | titanium dioxide | decreases methylation | ISO | Surf4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SURF4 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Surf4 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SURF4 mRNA | CTD | PMID:33387578 | Surf4 | Rat | tunicamycin | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of SURF4 mRNA | CTD | PMID:22378314|PMID:29453283 | Surf4 | Rat | valproic acid | increases expression | ISO | SURF4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SURF4 mRNA | CTD | PMID:23179753 | Surf4 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SURF4 mRNA | CTD | PMID:19015723 | Surf4 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SURF4 mRNA | CTD | PMID:23034163|PMID:23555832 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















