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Gene: Nlrp4a (NLR family, pyrin domain containing 4A) Rattus norvegicus

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Symbol:

Nlrp4a

Name:

NLR family, pyrin domain containing 4A

RGD ID:

1561918

Description:

Predicted to enable ATP binding activity. Predicted to be involved in regulation of inflammatory response. Predicted to be part of canonical inflammasome complex. Predicted to be active in cytoplasm. Orthologous to human NLRP4 (NLR family pyrin domain containing 4); INTERACTS WITH bisphenol A; glyphosate; trichloroethene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC292545; NACHT, LRR and PYD domains-containing protein 4A; RGD1561918; similar to NACHT, leucine rich repeat and PYD containing 4A

RGD Orthologs

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Nlrp4a (NLR family, pyrin domain containing 4A)	RGD	RGD
Other homologs ²
Homo sapiens (human):	NLRP4 (NLR family pyrin domain containing 4)	HGNC	Ensembl, OrthoDB, Panther, PhylomeDB
Alliance orthologs ³
Homo sapiens (human):	NLRP4 (NLR family pyrin domain containing 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NLRP4 (NLR family pyrin domain containing 4)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nlrp4a (NLR family, pyrin domain containing 4A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-76m11.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-26m3.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-178j11.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-124l13.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zgc:174180	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-236c18.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-255g12.8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-227e10.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-24k9.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:ch211-226o13.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	LOC108183498 (NLR family CARD domain-containing protein 3-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-236c18.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-165e24.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-15j1.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-100h4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:cabz01069012.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-71l4.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-238e22.8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-13n15.11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	LOC108183673 (NLR family CARD domain-containing protein 3-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-181d7.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-181d7.3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	LOC558818 (protein NLRC3-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-114l13.13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-114l13.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-77c4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-236c18.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-71l4.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-4f2.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-23k10.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-133h13.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zgc:174944	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	nlrc8 (NLR family CARD domain containing 8)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:rp71-7l19.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-27n6.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-250k18.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-232d10.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zgc:173709	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-205a14.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zgc:194906	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-151g22.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-271g18.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-197e7.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-233e3.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid)
Danio rerio (zebrafish):	nlrc7 (NLR family CARD domain containing 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-214b16.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	LOC101884563 (protein NLRC3-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-236p5.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:zfos-364h11.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-22k7.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	nlrp16 (NACHT, LRR and PYD domains-containing protein 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-237a4.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zgc:110171	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-4c4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-194e1.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-191a16.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-7i4.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-29j8.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-165o8.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-15j1.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-50f9.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-181d7.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-181d7.1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:dkey-222h21.8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-35e5.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkeyp-123a12.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-236p5.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-227p7.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-121n8.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-121n8.7	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:ch211-15j1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-114l13.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-11n14.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-82i20.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-264f17.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-196h24.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-59l11.10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-207e19.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-203c5.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-203c5.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	zmp:0000001020	Alliance	DIOPT (Ensembl Compara\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-201o1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-196h16.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-196h16.5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:ch211-171l17.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-222h21.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-191a16.5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-213a13.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-238e22.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-194e1.7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8197	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector)
Danio rerio (zebrafish):	nlrc6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-15j1.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	LOC110437934 (protein NLRC3-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|SonicParanoid)
Danio rerio (zebrafish):	nlrc9	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	nlrc9	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder)
Danio rerio (zebrafish):	nlrp3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-181d7.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:dkey-230i18.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Danio rerio (zebrafish):	si:dkey-121n8.5	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA)
Xenopus tropicalis (tropical clawed frog):	LOC108644478	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493406	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nlrp12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100491706	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100486737	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nlrp12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	75,086,422 - 75,173,426 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	75,086,422 - 75,173,426 (-)	Ensembl				GRCr8
mRatBN7.2	1	66,171,037 - 66,258,045 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	66,170,592 - 66,245,316 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	71,618,214 - 71,692,940 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	80,041,170 - 80,115,898 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	73,374,402 - 73,449,128 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	74,566,136 - 74,653,138 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	78,530,717 - 78,602,886 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	76,246,755 - 76,318,928 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	73,382,102 - 73,469,113 (-)	NCBI		F344_StmMcwi
Rnor_6.0	1	69,326,303 - 69,443,753 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	69,326,303 - 69,431,055 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	70,729,660 - 70,832,250 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	64,505,286 - 64,626,032 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	63,887,253 - 63,950,802 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

glyphosate (EXP)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

immune system process (IEA)

inflammatory response (IEA)

innate immune response (IEA)

regulation of inflammatory response (IBA)

Cellular Component

canonical inflammasome complex (IEA)

cytoplasm (IBA)

Molecular Function

ATP binding (IEA)

nucleotide binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Nlrp4a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	75,086,422 - 75,173,426 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	75,086,422 - 75,173,426 (-)	Ensembl				GRCr8
mRatBN7.2	1	66,171,037 - 66,258,045 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	66,170,592 - 66,245,316 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	71,618,214 - 71,692,940 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	80,041,170 - 80,115,898 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	73,374,402 - 73,449,128 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	1	74,566,136 - 74,653,138 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	1	78,530,717 - 78,602,886 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	1	76,246,755 - 76,318,928 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	1	73,382,102 - 73,469,113 (-)	NCBI		F344_StmMcwi
Rnor_6.0	1	69,326,303 - 69,443,753 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	69,326,303 - 69,431,055 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	70,729,660 - 70,832,250 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	64,505,286 - 64,626,032 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	63,887,253 - 63,950,802 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

Nlrp4a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	26,134,538 - 26,175,100 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	26,134,538 - 26,175,567 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	26,435,113 - 26,476,142 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	26,435,113 - 26,476,142 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	27,220,132 - 27,260,477 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	26,143,873 - 26,184,218 (+)	NCBI		MGSCv36	mm8
Celera	7	21,026,027 - 21,066,640 (+)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	14.78	NCBI

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	79
Count of miRNA genes:	68
Interacting mature miRNAs:	74
Transcripts:	ENSRNOT00000043739
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	34565726	79565726	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	3	12	40	46	44	16	23	16	6	89	54	21	10	38	28

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000043739 ⟹ ENSRNOP00000051298

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	75,086,422 - 75,173,426 (-)	Ensembl
mRatBN7.2 Ensembl	1	66,170,592 - 66,245,316 (-)	Ensembl
Rnor_6.0 Ensembl	1	69,326,303 - 69,431,055 (-)	Ensembl

RefSeq Acc Id:

NM_001106220 ⟹ NP_001099690

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	75,086,422 - 75,173,426 (-)	NCBI
mRatBN7.2	1	66,171,037 - 66,258,045 (-)	NCBI
Dahl_SR_JrHsd	1	74,566,136 - 74,653,138 (-)	NCBI
Lyon_Normotensive	1	78,530,717 - 78,602,886 (-)	NCBI
Lyon_Hypertensive	1	76,246,755 - 76,318,928 (-)	NCBI
F344_StmMcwi	1	73,382,102 - 73,469,113 (-)	NCBI
Rnor_6.0	1	69,326,303 - 69,431,055 (-)	NCBI
Rnor_5.0	1	70,729,660 - 70,832,250 (-)	NCBI
RGSC_v3.4	1	64,505,286 - 64,626,032 (-)	RGD
Celera	1	63,887,253 - 63,950,802 (-)	RGD

Sequence:

show sequence

ATCCTTGTACTCTATCTTCCTGAAGACACAATGGCATCTTTCTTTTCTGATTTTGGCCTTATGT
GGTACTTGGAAGAGTTAAACAAGAAAGAATTCATGAAGTTTAAGGAGTTCCTCAAACAGGAGAT
TTTGCAACTAGGGCTGAAGCAGGTTTCCTGGACAGAAGTGAAGAAAGCATCCCGGGAAGACCTT
GCCAGCTTACTGTTGAAACATTATGAAGAAAAGCAAGCCTGGGATATGACCTTCAATTTTTTCC
AGAAGATCAATAGGAAGGATCTCATAAAGAGGGCAAAAAGAGAGATTGACGGATACCCAAAATT
ATACCGAGCTCATCTGAAGACAAAGCTGACCCATGACAGTTCCAGAATATTTAATATTAATATT
CAGGATTTTTTGAAGGAGAAATTTACCAAGGATGACCATGATCGTTTTGAGACCCTTCTTCAAT
CAAAGGGAACTGAATCGAAGCCACAGGTGGTGGTCCTGAGTGGTGTTGCTGGAATTGGCAAGAC
ACTGATGTTGAAGAGGTTAATGCTGGCCTGGATAGAAGGCCTCGTGTTTCCATACAAATTCTCC
TACATCTTCTACTTCTGCTGTCAAGAAGTGAAGCAGTTGAAGACAGCTAGCCTGGCTGAACTGA
TCTCCAGAGAATGGCCTGACCCCTCAGCTCCCATAGAGGAGATTCTATCTGAACCTGAAAAACT
CTTATTTATCATTGACAGCTTAGAAGGGATCGAATGTGATTTGTTCAAATGTGATTCAGAGCTG
TGTGATAACTGCATGGAGAAGCAGCCAGTGAATATACTGTTAAGCAGTTTGCTCAGAAAGAAGA
TGCTCTTAGAAGCCTCTCTCCTCATTTCCACTACCCCAGAAACTTTTGAAAAGATGGAGGACAG
GATTGAGTACACACATGTGAAAATAATAACAGGACTTAATGAGAGCGATATTAAGATGTGTTTC
CACAGATTATTCCAAGATAGGAACAGAGCCCAGGAAGCCTTCAGTCTGGTGAGAGAAAATGAGC
AGATGTTGACTATATGTCAAGTCCCTGTGCTCTGCTGGATGGTGGCTACTTGTCTAAAAACAGA
AATAGAGAAGGGAAGAAATCTAGTCTCCACCTGCCGACGGACCACCTCTCTGTACACTACTTAT
ATCTTCAATTTGTTCATTCCCCAAAGTGCCCATTCTCCAAGTAAGAAAAGCCAAGACCAGCTGC
AGGGCTTGTGTTCTCTAGCTGCAGAGGGCATATGGACTGACACATTTGTTTTTACTGAGGAGGC
TCTCAGGAGAAATGGGATCCTGGATTCTGACATCCCCACACTATTGGACATTGGCATGCTTGGA
AAGATGGGAAAATTTGAAAATTGTTACATTTTCCTCCACCCATCTCTCCAGGAGGCCTGTGCTG
CCATCTTTTATCTGCTAAAGAGCCATGGAGACCACCCTATCGAGGACGTAAAAAGTGTAGAGGC
ACTCTTGTTTACATTTCTAAAGAAAGCCAAAGTACAGTGGATTTTGGGGGGCCGTTTCATCTTT
GGCCTTTTACATGAATCAGAACAAAAAAAGCTAGAGGCATTTTTTGGCCACCAGTTGTCCCAGG
AAATAAAACATCAGCTGTATCAGTGCCTGGAAACCATAAGTGTCAATGAAGAGCTTCAAGAACA
GATAGATGGCATGAAGTTGTTTTACTGTCTGTTTGAGATGGAGGATGAAGACTTTTTAATGGAA
GCAATGAACTATATGGAACAGATTAACTTTGTGGCTAAGGATTATTCTGATGTTATTGTTGCTG
CCTACTGCTTAAAACACTGTTATACACTGAAGAAACTATCCTTTTCTACCCAAAATATTCTTAA
TGAAGAACACGAACACAGCTGTATGGAAAATCTTCTAACCTGTTGGCGTCATATTTGCTCTGTG
CTCATAAACAGTAAGGACATCCAGGAACTCCAAATAAAAGACACTAATCTCAATGAACCAGCAT
TCTCAGTCTTGTATAATAGTTTGAAGTACTGCAATGACACCCTTAAAGTACTTGTGGAAAATAA
TGTGTTCTTCTTATGTGAAAAGTACCTGTTCTTTGAGTTGATTCAGAATTGCAATTTACAGCAC
TTGAACCTCAACCTCACATTCCTCTCCCACAGTGATGTGAAACTGTTGTGTGATGTCTTGAACC
AGGCAGAATGCAACATAGAAAAACTGGAGGTAGCAGCCTGTAACCTTTCACCTGATGACTGCAA
GATGTTTGCCTCTATCCTGATGAGCAGCAAGACTTTAAAGCAACTTAATTTGTCATCCAATATC
TTAGGAAAAGGGATATCCTCACTGTGCAAATCTTTGTGCCACCCAGACTGCATTCTGGAGCACT
TAGTTTTGGCCAAGTGTTCCCTCAGTGACCAATGTTGGGACTACCTTTCTGATGGTATTAGGCA
GAACAAAACTCTGAACCATCTTGATATCAGCTCCAATGATCTGAAGGATGAAGGACTGAAGGTT
CTCTGTAGGGCTCTGGCTCTCCCAAACAGTGTCCTCAAGTCACTATGTTTGAGACATTGTCTCA
TCACCACTAGTGGCTGCCAGGACCTGGCTGAAGTCTTAAGGAACAACCAGAACCTGACCAGTCT
ACAAATTTCATACAATAAGATAGAAGATGCTGGTGTGAAGCTGCTGTGTGATGCTATAAAACAA
CCCAACTGCCACTTAGAGGATCTTGGGTTGGAAGCCTGTGAGCTAACTGGTGCCTGTTGTGAGG
ACCTTGCTTCTACATTTACCCAGTGTAGGACTCTGTGGGGGATCAACCTGCTAAATAACACCTT
GGACTACACTGGCTTGGTTGTCCTGTGTGAGGCTTTGAGACAGCAAAAGTGTACCCCGCATGTA
CTTGGATTGCGAATTACTGATTTTGATAATGAAACCCAGGCATTTCTGGTTGCTGAGCAAGAGA
AAAATCCTGACTTGAGCATCCTAAGTGGCGTGTGAGCAGAAGCAGAAAACAAGGATGGAAATTC
TGATGCAAGAACCAGGGGTATACTCTGAACTCAAACTACCTCCATAAAAAGAAAGTAGGATCAT
TATTTTGGCCCATTGAATACAATGTTATAGATCAATAATGTTCTAATAAAATATGATTTCTTTG
TATCCCTTTTGGATATGTTTTGCAAGACAGATGTGGTTTTTTTATTTGTACTACATATTCAAAC
ATACTATAATTACATTTTATTTTCCATACTGGTATCTTGAGCACCCAATAAAGTGTTAAGTATC
TTTAAGTAGTGACTTGGAAATCTCTTAAAATGATATTTGCCTGTTAGTAGATTACTGGAGCCAT
AGAGTAAGTCTAAGCAGTAATGGTACCCTAAAAGGTTGTTGGGGAAGTTTTAATTGGCTCTGCA
TGAGAAACCTTTAGCAGAGTGTCTAGACTGGACACTCAGAATATGGAAACTGTTGCTGTTTTGC
GCTTTTTTCATTAAATAATAATTTATGCATTTTCCAACTTTACTGACTTCTAGTTTCAAATATT
AATGTTCTACATAGTTACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACAC
GTGTGTATATATGAACACATGAGCATCAGTACCTGCAAAGAACACAAGAGGGTGTCAGATGCCT
TGAAGCTAGAGCTTCAGGCAGTTATAAGCTGTCCATCATGGGTACTGGAAACTGGACTTACATC
CTGAAAGAACAGTATGTGAGCTTAACTGCTGAGCCATTTCTAACCTCTTGTTTATGTTGACTTT
GAAAGATAGTGGCCAAACTGAGATTCTGAGAAAGGCTGACTTGACTTGATTCTTAGACCTATTA
TCAATCTAATTAGGGTCTTCTGGTTTTGGATGAAGGTATTGAAAAGGCATATTTTTATATTTTT
ATTATTTCCTTGAATATTTAATACTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099690	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL84956	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051298
	ENSRNOP00000051298.3

RefSeq Acc Id:

NP_001099690 ⟸ NM_001106220

- UniProtKB:

D3ZUH1 (UniProtKB/TrEMBL), A6KS49 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEE
KQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTK
DDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEV
KQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPV
NILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRA
QEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSA
HSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYI
FLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKK
LEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINF
VAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQEL
QIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSH
SDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCK
SLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNS
VLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGL
EACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDN
ETQAFLVAEQEKNPDLSILSGV

hide sequence

Ensembl Acc Id:

ENSRNOP00000051298 ⟸ ENSRNOT00000043739

Protein Domains

NACHT Pyrin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZUH1-F1-model_v2	AlphaFold	D3ZUH1	1-982	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561918	AgrOrtholog
BioCyc Gene	G2FUF-60986	BioCyc
Ensembl Genes	ENSRNOG00000042030	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000043739	ENTREZGENE
	ENSRNOT00000043739.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.533.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
InterPro	DEATH-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
	NACHT_NTPase	UniProtKB/TrEMBL
	NLRC_HD2	UniProtKB/TrEMBL
	NLRP_innate_immun_reg	UniProtKB/TrEMBL
	NOD2_WH	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Pyrin	UniProtKB/TrEMBL
KEGG Report	rno:292545	UniProtKB/TrEMBL
NCBI Gene	292545	ENTREZGENE
PANTHER	NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12	UniProtKB/TrEMBL
	NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 4A	UniProtKB/TrEMBL
Pfam	LRR_6	UniProtKB/TrEMBL
	NACHT	UniProtKB/TrEMBL
	NLRC4_HD2	UniProtKB/TrEMBL
	NOD2_WH	UniProtKB/TrEMBL
	PAAD_DAPIN	UniProtKB/TrEMBL
PhenoGen	Nlrp4a	PhenoGen
PROSITE	DAPIN	UniProtKB/TrEMBL
	NACHT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000042030	RatGTEx
SMART	LRR_RI	UniProtKB/TrEMBL
	PYRIN	UniProtKB/TrEMBL
Superfamily-SCOP	DEATH_like	UniProtKB/TrEMBL
	RNI-like	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A6KS49	ENTREZGENE, UniProtKB/TrEMBL
	D3ZUH1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-29	Nlrp4a	NLR family, pyrin domain containing 4A	RGD1561918_predicted	similar to NACHT, leucine rich repeat and PYD containing 4A (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561918_predicted	similar to NACHT, leucine rich repeat and PYD containing 4A (predicted)	LOC292545	similar to NACHT, leucine rich repeat and PYD containing 4A	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC292545	similar to NACHT, leucine rich repeat and PYD containing 4A			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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