Symbol:
Nhs
Name:
NHS actin remodeling regulator
RGD ID:
1561818
Description:
Predicted to be involved in cell differentiation and lens development in camera-type eye. Predicted to be located in Golgi apparatus; cell junction; and nuclear body. Human ortholog(s) of this gene implicated in Nance-Horan syndrome and cataract 40. Orthologous to human NHS (NHS actin remodeling regulator); INTERACTS WITH bisphenol A; gentamycin; paracetamol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
actin remodeling regulator NHS; LOC317494; Nance-Horan syndrome (congenital cataracts and dental anomalies); Nance-Horan syndrome (human); Nance-Horan syndrome protein; RGD1561818; similar to Nance-Horan syndrome protein
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 36,185,067 - 36,524,711 (+) NCBI GRCr8 mRatBN7.2 X 32,553,300 - 32,892,961 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 32,552,026 - 32,889,992 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 33,582,578 - 33,916,873 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 37,022,712 - 37,359,427 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 33,207,548 - 33,541,837 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 34,312,102 - 34,675,912 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 34,623,405 - 34,673,742 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 34,656,286 - 35,018,650 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 53,321,827 - 53,720,326 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera X 32,845,030 - 33,180,545 (+) NCBI Celera Cytogenetic Map X q14 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Nhs Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 36,185,067 - 36,524,711 (+) NCBI GRCr8 mRatBN7.2 X 32,553,300 - 32,892,961 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 32,552,026 - 32,889,992 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 33,582,578 - 33,916,873 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 37,022,712 - 37,359,427 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 33,207,548 - 33,541,837 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 34,312,102 - 34,675,912 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 34,623,405 - 34,673,742 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 34,656,286 - 35,018,650 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 53,321,827 - 53,720,326 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera X 32,845,030 - 33,180,545 (+) NCBI Celera Cytogenetic Map X q14 NCBI
NHS Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 17,375,200 - 17,735,994 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 17,375,200 - 17,735,994 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 17,393,323 - 17,754,114 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 17,303,464 - 17,664,035 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 X 17,153,199 - 17,513,768 NCBI Celera X 21,515,624 - 21,873,432 (+) NCBI Celera Cytogenetic Map X p22.2-p22.13 NCBI HuRef X 15,153,213 - 15,512,673 (+) NCBI HuRef CHM1_1 X 17,424,184 - 17,784,494 (+) NCBI CHM1_1 T2T-CHM13v2.0 X 16,957,799 - 17,318,610 (+) NCBI T2T-CHM13v2.0
Nhs Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 160,616,286 - 160,942,437 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 160,616,292 - 160,942,726 (-) Ensembl GRCm39 Ensembl GRCm38 X 161,833,290 - 162,159,441 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 161,833,296 - 162,159,730 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 158,274,200 - 158,597,722 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 157,180,373 - 157,503,895 (-) NCBI MGSCv36 mm8 Celera X 145,069,096 - 145,393,381 (-) NCBI Celera Cytogenetic Map X F4 NCBI cM Map X 74.17 NCBI
Nhs Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955519 599,682 - 918,762 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955519 596,216 - 919,352 (-) NCBI ChiLan1.0 ChiLan1.0
NHS Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 19,163,540 - 19,534,073 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 19,166,931 - 19,538,278 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 9,988,584 - 10,359,110 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 17,357,898 - 17,728,178 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 17,358,416 - 17,728,178 (+) Ensembl panpan1.1 panPan2
NHS Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 13,487,919 - 13,834,869 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 13,488,515 - 13,831,386 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 13,339,834 - 13,686,761 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 13,451,227 - 13,798,368 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 13,451,793 - 13,795,287 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 13,518,311 - 13,864,906 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 13,504,402 - 13,851,231 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 13,573,553 - 13,920,854 (+) NCBI UU_Cfam_GSD_1.0
Nhs Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 6,887,249 - 6,971,110 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936470 6,919,623 - 6,971,125 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936470 6,632,724 - 6,967,878 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
NHS Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 14,097,006 - 14,206,568 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 13,854,950 - 14,209,085 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 14,951,338 - 15,302,337 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
NHS Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 15,803,386 - 16,183,809 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 16,168,609 - 16,183,787 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666056 17,683,202 - 18,052,952 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Nhs
.
Predicted Target Of
Count of predictions: 103 Count of miRNA genes: 79 Interacting mature miRNAs: 93 Transcripts: ENSRNOT00000041924 Prediction methods: Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan Result types: miRGate_prediction
1598873 Memor2 Memory QTL 2 2.5 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) X 20990947 41052531 Rat 1298071 Edpm12 Estrogen-dependent pituitary mass QTL 12 3.2 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) X 2927898 47927898 Rat 2290375 Gluco34 Glucose level QTL 34 2.75 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) X 20990947 41203591 Rat 731181 Uae27 Urinary albumin excretion QTL 27 2.7 0.0059 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) X 1 43491017 Rat 61430 Cia18 Collagen induced arthritis QTL 18 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 14843113 120568734 Rat 10755455 Coatc13 Coat color QTL 13 0 coat/hair pigmentation trait (VT:0010463) pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812) 7 4406000 49406000 Rat 631666 Iddm5 Insulin dependent diabetes mellitus QTL 5 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 4494549 49494549 Rat 71116 Niddm16 Non-insulin dependent diabetes mellitus QTL 16 7.81 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) X 15297802 60297802 Rat
DXRat25
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 X 36,296,903 - 36,297,020 (+) Marker Load Pipeline mRatBN7.2 X 32,665,143 - 32,665,260 (+) MAPPER mRatBN7.2 Rnor_6.0 X 34,424,518 - 34,424,634 NCBI Rnor6.0 Rnor_5.0 X 34,768,466 - 34,768,582 UniSTS Rnor5.0 Celera X 32,956,567 - 32,956,683 UniSTS RH 3.4 Map X 474.4 RGD RH 3.4 Map X 474.4 UniSTS RH 2.0 Map 21 361.4 RGD FHH x ACI Map X 14.5099 RGD Cytogenetic Map X q21 UniSTS
DXGot26
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 32,632,625 - 32,632,857 (+) MAPPER mRatBN7.2 Rnor_6.0 X 34,392,155 - 34,392,386 NCBI Rnor6.0 Rnor_5.0 X 34,735,954 - 34,736,185 UniSTS Rnor5.0 RGSC_v3.4 X 53,457,104 - 53,457,336 RGD RGSC3.4 RGSC_v3.4 X 53,457,105 - 53,457,336 UniSTS RGSC3.4 RGSC_v3.1 X 53,510,574 - 53,510,805 RGD Celera X 32,924,132 - 32,924,363 UniSTS RH 3.4 Map X 464.9 UniSTS RH 3.4 Map X 464.9 RGD RH 2.0 Map 21 358.3 RGD Cytogenetic Map X q21 UniSTS
AW527792
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 32,718,432 - 32,718,567 (+) MAPPER mRatBN7.2 Rnor_6.0 X 34,477,929 - 34,478,063 NCBI Rnor6.0 Rnor_5.0 X 34,821,916 - 34,822,050 UniSTS Rnor5.0 RGSC_v3.4 X 53,542,979 - 53,543,113 UniSTS RGSC3.4 Celera X 33,009,500 - 33,009,634 UniSTS RH 3.4 Map X 474.4 UniSTS Cytogenetic Map X q21 UniSTS
RH133422
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 32,552,422 - 32,552,609 (+) MAPPER mRatBN7.2 Rnor_6.0 X 34,312,689 - 34,312,875 NCBI Rnor6.0 Rnor_5.0 X 34,656,540 - 34,656,726 UniSTS Rnor5.0 RGSC_v3.4 X 53,320,950 - 53,321,136 UniSTS RGSC3.4 Celera X 32,844,153 - 32,844,339 UniSTS RH 3.4 Map X 467.1 UniSTS Cytogenetic Map X q21 UniSTS
fi17a01.x1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 2 176,807,742 - 176,807,800 (-) MAPPER mRatBN7.2 mRatBN7.2 X 32,555,266 - 32,555,943 (+) MAPPER mRatBN7.2 Rnor_6.0 X 34,315,533 - 34,316,209 NCBI Rnor6.0 Rnor_6.0 2 190,570,717 - 190,570,774 NCBI Rnor6.0 Rnor_5.0 2 214,303,158 - 214,303,215 UniSTS Rnor5.0 Rnor_5.0 X 34,659,384 - 34,660,060 UniSTS Rnor5.0 RGSC_v3.4 X 53,323,794 - 53,324,470 UniSTS RGSC3.4 RGSC_v3.4 2 183,795,076 - 183,795,133 UniSTS RGSC3.4 Celera 2 173,769,534 - 173,769,591 UniSTS Celera X 32,846,997 - 32,847,673 UniSTS Cytogenetic Map X q21 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
10
49
113
79
78
47
25
47
6
205
96
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000041924 ⟹ ENSRNOP00000039704
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 32,552,026 - 32,889,992 (+) Ensembl Rnor_6.0 Ensembl X 34,623,405 - 34,672,940 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000091746 ⟹ ENSRNOP00000070291
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 32,552,026 - 32,889,992 (+) Ensembl Rnor_6.0 Ensembl X 34,630,048 - 34,673,742 (+) Ensembl
RefSeq Acc Id:
NM_001191733 ⟹ NP_001178662
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 36,185,067 - 36,521,739 (+) NCBI mRatBN7.2 X 32,553,300 - 32,889,992 (+) NCBI Rnor_6.0 X 34,313,566 - 34,672,940 (+) NCBI Rnor_5.0 X 34,656,286 - 35,018,650 (+) NCBI Celera X 32,845,030 - 33,180,545 (+) NCBI
Sequence:
CTCACACACACACACACATACACACACGCCCATTTATATAGGCGGCGGCAGTGGCCAGGGCGGCGGCAACGGGCTCAGAAGCGATGGAGCTGAGCCGACTGACCCCGGTTGGGAGCAAGTGAAGAGGA
hide sequence
RefSeq Acc Id:
NM_001414726 ⟹ NP_001401655
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 36,185,067 - 36,524,708 (+) NCBI mRatBN7.2 X 32,553,300 - 32,892,961 (+) NCBI
RefSeq Acc Id:
XM_008773173 ⟹ XP_008771395
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 36,392,388 - 36,524,711 (+) NCBI mRatBN7.2 X 32,783,851 - 32,892,961 (+) NCBI Rnor_6.0 X 34,569,870 - 34,675,912 (+) NCBI
Sequence:
GTGTAGTCCAAATTGTCCTCAAACTCACAGAAATCCCTGCCTCAGCTTTCATGGTGCCCAGACT
hide sequence
RefSeq Acc Id:
XM_017602085 ⟹ XP_017457574
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 36,431,116 - 36,524,711 (+) NCBI mRatBN7.2 X 32,799,376 - 32,892,961 (+) NCBI Rnor_6.0 X 34,589,036 - 34,675,912 (+) NCBI
Sequence:
AACTAAGATAAAAGAAAAAAGGAAGGGGGAATGCGGTCATAACGCACCAAGGCGCTGGAAAGCCCCCTCCCTCCCCGAGAGGCCTCTCCTTTGCGGGGAGAGGAGAAGAGGCAGAGATCCCCAGCCCA
hide sequence
RefSeq Acc Id:
NP_001178662 ⟸ NM_001191733
- Peptide Label:
isoform 2
- UniProtKB:
F1LU76 (UniProtKB/TrEMBL)
- Sequence:
MPFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRREEAEATEPDEPPRVPPAPLPLPPPPPPSMPAPAEQDQQPPSEAREAGEESVAGVPEAASATGEASEAAAEAVLLMLDLCAVSNA
hide sequence
RefSeq Acc Id:
XP_008771395 ⟸ XM_008773173
- Peptide Label:
isoform X2
- Sequence:
MALACCMPKNEAVSNLDIESKLSVYYRAPWHQQRNIFLPVTRPPCVEELHRHARQSLQALRREHRSRSDRREQRAAAPVPIAAPPLPAYPPAHSQRRREAKDRHLLTFNSTRSPSPTECCHMAPWSRK
hide sequence
RefSeq Acc Id:
XP_017457574 ⟸ XM_017602085
- Peptide Label:
isoform X1
- Sequence:
MPTSPDGRIPGEPARGPAARPGRTGGRISAPGERSTGGLPRAEPEPERTPGEASLGAAPHRNPTGCSTTRSPGHTAVSNLDIESKLSVYYRAPWHQQRNIFLPVTRPPCVEELHRHARQSLQALRREH
hide sequence
Ensembl Acc Id:
ENSRNOP00000039704 ⟸ ENSRNOT00000041924
Ensembl Acc Id:
ENSRNOP00000070291 ⟸ ENSRNOT00000091746
RefSeq Acc Id:
NP_001401655 ⟸ NM_001414726
- Peptide Label:
isoform 1
- UniProtKB:
A0A0G2JXJ0 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2015-11-30
Nhs
NHS actin remodeling regulator
Nhs
Nance-Horan syndrome (congenital cataracts and dental anomalies)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2013-01-22
Nhs
Nance-Horan syndrome (congenital cataracts and dental anomalies)
Nhs
Nance-Horan syndrome (human)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-02-29
Nhs
Nance-Horan syndrome (human)
RGD1561818_predicted
similar to Nance-Horan syndrome protein (predicted)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2006-03-07
RGD1561818_predicted
similar to Nance-Horan syndrome protein (predicted)
LOC317494
similar to Nance-Horan syndrome protein
Symbol and Name status set to approved
1299863 APPROVED
2006-02-09
LOC317494
similar to Nance-Horan syndrome protein
Symbol and Name status set to provisional
70820 PROVISIONAL
