Eif2d (eukaryotic translation initiation factor 2D) - Rat Genome Database

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Gene: Eif2d (eukaryotic translation initiation factor 2D) Rattus norvegicus
Analyze
Symbol: Eif2d
Name: eukaryotic translation initiation factor 2D
RGD ID: 1561765
Description: Predicted to enable translation initiation factor activity. Predicted to be involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Predicted to be located in cytoplasm. Orthologous to human EIF2D (eukaryotic translation initiation factor 2D); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LGTN; ligatin; LOC498225; similar to ligatin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Note: The name of this locus was changed from ligatin to eukaryotic translation initiation factor 2D based on the gene characterization of the human ortholog reported in PMID:20566627. [18 Aug 2011]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,168,161 - 45,189,362 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1345,139,967 - 45,191,974 (+)EnsemblGRCr8
mRatBN7.21342,615,901 - 42,637,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,615,911 - 42,639,719 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1345,222,598 - 45,241,563 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,510,729 - 46,529,694 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,774,845 - 43,793,785 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,935,138 - 47,958,459 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,935,163 - 47,954,090 (+)Ensemblrn6Rnor6.0
Rnor_5.01353,011,077 - 53,033,762 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,099,725 - 44,118,652 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1342,961,793 - 42,980,721 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO,ISS)
cytosol  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:20566627   PMID:20713520  


Genomics

Comparative Map Data
Eif2d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,168,161 - 45,189,362 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1345,139,967 - 45,191,974 (+)EnsemblGRCr8
mRatBN7.21342,615,901 - 42,637,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,615,911 - 42,639,719 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1345,222,598 - 45,241,563 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01346,510,729 - 46,529,694 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01343,774,845 - 43,793,785 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01347,935,138 - 47,958,459 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,935,163 - 47,954,090 (+)Ensemblrn6Rnor6.0
Rnor_5.01353,011,077 - 53,033,762 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41344,099,725 - 44,118,652 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1342,961,793 - 42,980,721 (+)NCBICelera
Cytogenetic Map13q13NCBI
EIF2D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,569,146 - 206,612,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1206,571,292 - 206,612,514 (-)Ensemblhg38GRCh38
GRCh371206,764,974 - 206,785,818 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361204,831,597 - 204,852,527 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341203,153,371 - 203,174,299NCBI
Celera1180,016,423 - 180,037,351 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1177,463,289 - 177,484,217 (-)NCBIHuRef
CHM1_11208,037,181 - 208,058,090 (-)NCBICHM1_1
T2T-CHM13v2.01205,827,369 - 205,876,640 (-)NCBIT2T-CHM13v2.0
Eif2d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,080,903 - 131,115,396 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,080,918 - 131,115,395 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381131,153,172 - 131,187,659 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,153,181 - 131,187,658 (+)Ensemblmm10GRCm38
MGSCv371133,049,784 - 133,070,048 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361132,980,782 - 132,999,780 (+)NCBIMGSCv36mm8
Celera1133,775,887 - 133,795,744 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.9NCBI
Eif2d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,163,632 - 42,181,337 (-)Ensembl
ChiLan1.0NW_00495540642,163,508 - 42,181,482 (-)NCBIChiLan1.0ChiLan1.0
EIF2D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,762,926 - 42,784,684 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1142,728,446 - 42,750,211 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,193,709 - 182,214,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11186,473,496 - 186,494,371 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,473,496 - 186,494,896 (-)EnsemblpanPan2panpan1.1
EIF2D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1382,851,972 - 2,871,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl382,851,978 - 2,871,518 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha382,944,091 - 2,963,655 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0382,849,269 - 2,868,948 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl382,846,143 - 2,868,902 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1382,842,501 - 2,862,019 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0383,235,478 - 3,255,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0383,436,042 - 3,455,816 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eif2d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,725,272 - 68,745,708 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365575,965,504 - 5,986,064 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365575,965,496 - 5,985,993 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl967,240,588 - 67,261,223 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1967,240,586 - 67,261,250 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2973,593,837 - 73,614,045 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,752,852 - 22,773,566 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,752,926 - 22,773,568 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605523,451,194 - 23,471,916 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif2d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248074,818,585 - 4,836,280 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248074,818,652 - 4,834,898 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Eif2d
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1104,631,780 - 4,656,157 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Eif2d
142 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:24
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000006768
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131186625456866254Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132485392569853925Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131244842147969993Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131746828262468282Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131238432057384320Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134373632747969993Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132433543255601132Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131244842148744906Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132624480871244808Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133379409678794096Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133483494779834947Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133379409660914504Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132624480871244808Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131771133662711336Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131186625456866254Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006768   ⟹   ENSRNOP00000006768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,177 - 45,189,324 (+)Ensembl
mRatBN7.2 Ensembl1342,615,911 - 42,634,854 (+)Ensembl
Rnor_6.0 Ensembl1347,935,163 - 47,954,090 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111867   ⟹   ENSRNOP00000079849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,188 - 45,191,909 (+)Ensembl
mRatBN7.2 Ensembl1342,615,911 - 42,639,589 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114517   ⟹   ENSRNOP00000094285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,177 - 45,185,559 (+)Ensembl
mRatBN7.2 Ensembl1342,615,911 - 42,633,304 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117695   ⟹   ENSRNOP00000086963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,177 - 45,191,974 (+)Ensembl
mRatBN7.2 Ensembl1342,615,911 - 42,639,719 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151553   ⟹   ENSRNOP00000104595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,139,967 - 45,187,104 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157629   ⟹   ENSRNOP00000111433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,188 - 45,191,909 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162909   ⟹   ENSRNOP00000100988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1345,168,177 - 45,185,739 (+)Ensembl
RefSeq Acc Id: NM_001017489   ⟹   NP_001017489
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,168,177 - 45,187,104 (+)NCBI
mRatBN7.21342,615,920 - 42,634,849 (+)NCBI
Rnor_6.01347,935,163 - 47,954,090 (+)NCBI
Rnor_5.01353,011,077 - 53,033,762 (+)NCBI
RGSC_v3.41344,099,725 - 44,118,652 (+)RGD
Celera1342,961,793 - 42,980,721 (+)RGD
Sequence:
RefSeq Acc Id: XM_006249790   ⟹   XP_006249852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,168,161 - 45,189,362 (+)NCBI
mRatBN7.21342,615,901 - 42,637,107 (+)NCBI
Rnor_6.01347,935,138 - 47,958,459 (+)NCBI
Rnor_5.01353,011,077 - 53,033,762 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090962   ⟹   XP_038946890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,172,384 - 45,187,109 (+)NCBI
mRatBN7.21342,620,127 - 42,634,854 (+)NCBI
RefSeq Acc Id: XM_063272531   ⟹   XP_063128601
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,168,161 - 45,189,247 (+)NCBI
RefSeq Acc Id: XR_010056927
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81345,168,163 - 45,179,901 (+)NCBI
RefSeq Acc Id: NP_001017489   ⟸   NM_001017489
- UniProtKB: Q5PPG7 (UniProtKB/Swiss-Prot),   A6IC14 (UniProtKB/TrEMBL),   A0A8I6AJ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249852   ⟸   XM_006249790
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZPF1 (UniProtKB/TrEMBL),   A0A8I6AJ85 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006768   ⟸   ENSRNOT00000006768
RefSeq Acc Id: XP_038946890   ⟸   XM_039090962
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000079849   ⟸   ENSRNOT00000111867
Ensembl Acc Id: ENSRNOP00000086963   ⟸   ENSRNOT00000117695
Ensembl Acc Id: ENSRNOP00000094285   ⟸   ENSRNOT00000114517
RefSeq Acc Id: XP_063128601   ⟸   XM_063272531
- Peptide Label: isoform X1
- UniProtKB: Q5PPG7 (UniProtKB/Swiss-Prot),   A0A8I6AJ85 (UniProtKB/TrEMBL),   A6IC14 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100988   ⟸   ENSRNOT00000162909
Ensembl Acc Id: ENSRNOP00000111433   ⟸   ENSRNOT00000157629
Ensembl Acc Id: ENSRNOP00000104595   ⟸   ENSRNOT00000151553
Protein Domains
DM2   PUA   SUI1   SWIB/MDM2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPG7-F1-model_v2 AlphaFold Q5PPG7 1-570 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698793
Promoter ID:EPDNEW_R9318
Type:initiation region
Name:Eif2d_1
Description:eukaryotic translation initiation factor 2D
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01347,935,159 - 47,935,219EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561765 AgrOrtholog
BioCyc Gene G2FUF-18355 BioCyc
Ensembl Genes ENSRNOG00000004910 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006768 ENTREZGENE
  ENSRNOT00000006768.5 UniProtKB/Swiss-Prot
  ENSRNOT00000111867 ENTREZGENE
  ENSRNOT00000117695 ENTREZGENE
  ENSRNOT00000151553 ENTREZGENE
Gene3D-CATH 3.10.400.20 UniProtKB/Swiss-Prot
  SUI1-like domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7314085 IMAGE-MGC_LOAD
InterPro EIF2D UniProtKB/Swiss-Prot
  eIF2D_N UniProtKB/Swiss-Prot
  eIF2D_SUI1 UniProtKB/Swiss-Prot
  Pre-PUA UniProtKB/Swiss-Prot
  PUA UniProtKB/Swiss-Prot
  PUA-like_sf UniProtKB/Swiss-Prot
  PUA_eIF2d-like UniProtKB/Swiss-Prot
  SUI1 UniProtKB/Swiss-Prot
  SUI1_dom_sf UniProtKB/Swiss-Prot
  SWIB_MDM2_dom_sf UniProtKB/Swiss-Prot
  SWIB_MDM2_domain UniProtKB/Swiss-Prot
KEGG Report rno:498225 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105736 IMAGE-MGC_LOAD
NCBI Gene 498225 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2D UniProtKB/Swiss-Prot
  PTHR12217 UniProtKB/Swiss-Prot
Pfam Pre-PUA UniProtKB/Swiss-Prot
  SUI1 UniProtKB/Swiss-Prot
  WH_eIF2D UniProtKB/Swiss-Prot
PhenoGen Eif2d PhenoGen
PROSITE PUA UniProtKB/Swiss-Prot
  SUI1 UniProtKB/Swiss-Prot
  SWIB_MDM2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004910 RatGTEx
SMART PUA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47592 UniProtKB/Swiss-Prot
  SSF55159 UniProtKB/Swiss-Prot
  SSF88697 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFL6_RAT UniProtKB/TrEMBL
  A0A8I6AJ85 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L822_RAT UniProtKB/TrEMBL
  A0ABK0LG57_RAT UniProtKB/TrEMBL
  A0ABK0M371_RAT UniProtKB/TrEMBL
  A6IC14 ENTREZGENE, UniProtKB/TrEMBL
  EIF2D_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Lgtn  ligatin   Lgtn_predicted  ligatin (predicted)  'predicted' is removed 2292626 APPROVED
2007-02-02 Lgtn_predicted  ligatin (predicted)  LOC498225  similar to ligatin  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498225  similar to ligatin      Symbol and Name status set to provisional 70820 PROVISIONAL