Edar (ectodysplasin-A receptor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Edar (ectodysplasin-A receptor) Rattus norvegicus
Analyze
Symbol: Edar
Name: ectodysplasin-A receptor
RGD ID: 1561714
Description: Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cytokine-mediated signaling pathway; positive regulation of JNK cascade; and positive regulation of canonical NF-kappaB signal transduction. Predicted to act upstream of or within several processes, including hair follicle development; positive regulation of non-canonical NF-kappaB signal transduction; and salivary gland cavitation. Predicted to be located in apical part of cell. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC365581; RGD1561714; similar to Ectodysplasin-A receptor; similar to Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless); tumor necrosis factor receptor superfamily member EDAR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82027,130,934 - 27,209,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2027,130,934 - 27,209,630 (-)EnsemblGRCr8
mRatBN7.22026,587,836 - 26,666,543 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,587,839 - 26,666,494 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2027,595,453 - 27,623,881 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,981,678 - 27,010,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,726,632 - 27,755,014 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,179,132 - 28,263,092 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,179,140 - 28,263,037 (-)Ensemblrn6Rnor6.0
Rnor_5.02029,996,972 - 30,079,875 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42037,135,534 - 37,164,197 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2028,038,358 - 28,066,702 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
apical part of cell  (IEA,ISO)
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia. Del-Pozo J, etal., Dis Model Mech. 2019 Apr 25;12(4). pii: 12/4/dmm037804. doi: 10.1242/dmm.037804.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia. Monreal AW, etal., Nat Genet. 1999 Aug;22(4):366-9.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:544312   PMID:11039935   PMID:12629675   PMID:18508042  


Genomics

Comparative Map Data
Edar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82027,130,934 - 27,209,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2027,130,934 - 27,209,630 (-)EnsemblGRCr8
mRatBN7.22026,587,836 - 26,666,543 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,587,839 - 26,666,494 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2027,595,453 - 27,623,881 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,981,678 - 27,010,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,726,632 - 27,755,014 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,179,132 - 28,263,092 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,179,140 - 28,263,037 (-)Ensemblrn6Rnor6.0
Rnor_5.02029,996,972 - 30,079,875 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42037,135,534 - 37,164,197 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2028,038,358 - 28,066,702 (-)NCBICelera
Cytogenetic Map20q11NCBI
EDAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382108,894,471 - 108,989,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2108,894,471 - 108,989,372 (-)Ensemblhg38GRCh38
GRCh372109,510,927 - 109,605,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,877,361 - 108,972,260 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342108,969,448 - 109,064,346NCBI
Celera2103,820,860 - 103,915,790 (-)NCBICelera
Cytogenetic Map2q13NCBI
HuRef2103,109,351 - 103,204,259 (-)NCBIHuRef
CHM1_12109,515,194 - 109,610,098 (-)NCBICHM1_1
T2T-CHM13v2.02109,355,029 - 109,449,802 (-)NCBIT2T-CHM13v2.0
Edar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391058,436,602 - 58,511,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1058,436,611 - 58,511,476 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381058,600,780 - 58,675,696 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1058,600,789 - 58,675,654 (-)Ensemblmm10GRCm38
MGSCv371058,063,536 - 58,138,444 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361058,582,058 - 58,656,978 (-)NCBIMGSCv36mm8
MGSCv361057,996,146 - 58,071,053 (-)NCBIMGSCv36mm8
Cytogenetic Map10B4NCBI
cM Map1029.37NCBI
Edar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547012,309,048 - 12,362,570 (-)Ensembl
ChiLan1.0NW_00495547012,310,680 - 12,362,555 (-)NCBIChiLan1.0ChiLan1.0
EDAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,025,847 - 21,060,049 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A21,008,536 - 21,062,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A95,132,396 - 95,172,218 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,146,499 - 110,241,556 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A110,146,499 - 110,234,398 (-)EnsemblpanPan2panpan1.1
EDAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11034,873,311 - 34,943,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1034,848,526 - 34,940,784 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1034,772,071 - 34,866,543 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01035,700,824 - 35,795,378 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1035,700,812 - 35,795,448 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11035,430,446 - 35,524,880 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01035,712,643 - 35,807,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01035,901,219 - 35,995,761 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Edar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629291,938,934 - 91,970,049 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829429,561 - 458,943 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936829429,667 - 458,943 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,396,330 - 47,465,784 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1347,396,303 - 47,466,234 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,558,908 - 49,626,194 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EDAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11412,430,405 - 12,527,160 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1412,433,418 - 12,468,841 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660807,173,441 - 7,274,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Edar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474911,983,550 - 11,998,918 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474911,981,782 - 11,998,933 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Edar
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11824,753,078 - 24,781,425 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Edar
480 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:801
Count of miRNA genes:313
Interacting mature miRNAs:400
Transcripts:ENSRNOT00000030348
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202668936256021148Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202668936256021148Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)202074558556021148Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202679235356021148Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202668936256021148Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202668936256021148Rat

Markers in Region
D20Rat36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22026,621,485 - 26,621,635 (+)MAPPERmRatBN7.2
Rnor_6.02028,218,193 - 28,218,342NCBIRnor6.0
Rnor_5.02030,035,898 - 30,036,047UniSTSRnor5.0
RGSC_v3.42037,132,181 - 37,132,331RGDRGSC3.4
RGSC_v3.42037,132,182 - 37,132,331UniSTSRGSC3.4
Celera2028,069,905 - 28,070,055UniSTS
RGSC_v3.12037,145,981 - 37,146,131RGD
SHRSP x BN Map2021.46UniSTS
SHRSP x BN Map2021.46RGD
FHH x ACI Map2012.4099RGD
Cytogenetic Map20q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 26 137 70 75 44 69 44 6 259 121 10 120 72 82 31 6 6

Sequence


Ensembl Acc Id: ENSRNOT00000030348   ⟹   ENSRNOP00000029258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2027,130,934 - 27,209,630 (-)Ensembl
mRatBN7.2 Ensembl2026,587,839 - 26,666,494 (-)Ensembl
Rnor_6.0 Ensembl2028,179,140 - 28,263,037 (-)Ensembl
RefSeq Acc Id: NM_001191899   ⟹   NP_001178828
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82027,130,934 - 27,209,630 (-)NCBI
mRatBN7.22026,587,836 - 26,666,543 (-)NCBI
Rnor_6.02028,181,194 - 28,214,990 (-)NCBI
Rnor_5.02029,996,972 - 30,079,875 (-)NCBI
Celera2028,038,358 - 28,066,702 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098901   ⟹   XP_038954829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82027,130,934 - 27,209,630 (-)NCBI
mRatBN7.22026,587,836 - 26,666,543 (-)NCBI
RefSeq Acc Id: XM_039098902   ⟹   XP_038954830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82027,130,934 - 27,209,672 (-)NCBI
mRatBN7.22026,587,836 - 26,666,543 (-)NCBI
RefSeq Acc Id: XM_039098903   ⟹   XP_038954831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82027,130,934 - 27,209,645 (-)NCBI
mRatBN7.22026,587,836 - 26,666,543 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178828 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954829 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954830 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954831 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000029258
  ENSRNOP00000029258.5
RefSeq Acc Id: NP_001178828   ⟸   NM_001191899
- Peptide Label: precursor
- UniProtKB: D3ZGP2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000029258   ⟸   ENSRNOT00000030348
RefSeq Acc Id: XP_038954831   ⟸   XM_039098903
- Peptide Label: isoform X3
- UniProtKB: D3ZGP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954830   ⟸   XM_039098902
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038954829   ⟸   XM_039098901
- Peptide Label: isoform X1
Protein Domains
Tumor necrosis factor receptor superfamily member

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZGP2-F1-model_v2 AlphaFold D3ZGP2 1-448 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701583
Promoter ID:EPDNEW_R12107
Type:initiation region
Name:Edar_1
Description:ectodysplasin-A receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02028,263,067 - 28,263,127EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561714 AgrOrtholog
BioCyc Gene G2FUF-3783 BioCyc
Ensembl Genes ENSRNOG00000028598 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030348 ENTREZGENE
  ENSRNOT00000030348.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
InterPro DEATH-like UniProtKB/TrEMBL
  Death_EDAR UniProtKB/TrEMBL
  EDAR_N UniProtKB/TrEMBL
  TNR19/27/EDAR UniProtKB/TrEMBL
NCBI Gene 365581 ENTREZGENE
PANTHER TNFR-CYS DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR UniProtKB/TrEMBL
Pfam Death_EDAR UniProtKB/TrEMBL
PhenoGen Edar PhenoGen
RatGTEx ENSRNOG00000028598 RatGTEx
Superfamily-SCOP DEATH_like UniProtKB/TrEMBL
UniProt D3ZGP2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Edar  ectodysplasin-A receptor  LOC678867  similar to Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless)  Data merged from RGD:1595551 1643240 APPROVED
2008-02-29 Edar  ectodysplasin-A receptor  RGD1561714_predicted  similar to Ectodysplasin-A receptor (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC678867  similar to Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1561714_predicted  similar to Ectodysplasin-A receptor (predicted)  LOC365581  similar to Ectodysplasin-A receptor  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC365581  similar to Ectodysplasin-A receptor      Symbol and Name status set to provisional 70820 PROVISIONAL