Osbpl8 (oxysterol binding protein-like 8) - Rat Genome Database

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Gene: Osbpl8 (oxysterol binding protein-like 8) Rattus norvegicus
Analyze
Symbol: Osbpl8
Name: oxysterol binding protein-like 8
RGD ID: 1561474
Description: Predicted to enable cholesterol binding activity; phosphatidylserine transfer activity; and phospholipid binding activity. Predicted to be involved in several processes, including fat cell differentiation; positive regulation of D-glucose import; and triglyceride homeostasis. Predicted to act upstream of or within negative regulation of cell migration; positive regulation of signal transduction; and protein localization to nuclear pore. Predicted to be located in cortical endoplasmic reticulum and nuclear membrane. Predicted to be active in cytosol and membrane. Orthologous to human OSBPL8 (oxysterol binding protein like 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC314824; LOC314824; oxysterol-binding protein-related protein 8; RGD1561474; similar to oxysterol-binding protein-like protein 8 isoform a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,483,259 - 48,636,151 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl748,483,022 - 48,636,151 (+)EnsemblGRCr8
mRatBN7.2746,596,944 - 46,749,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx748,496,671 - 48,649,451 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,699,816 - 50,852,600 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,477,574 - 50,630,354 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,878,906 - 54,030,110 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)Ensemblrn6Rnor6.0
Rnor_5.0753,888,262 - 54,039,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4750,308,713 - 50,313,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera743,400,573 - 43,550,915 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
cefaloridine  (EXP)
cisplatin  (ISO)
clozapine  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
eugenol  (EXP)
FR900359  (ISO)
geldanamycin  (ISO)
glafenine  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ketoconazole  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rimonabant  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetracycline  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17428193   PMID:19946888   PMID:21441927   PMID:22683860   PMID:23028956   PMID:23812417   PMID:26206935  


Genomics

Comparative Map Data
Osbpl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,483,259 - 48,636,151 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl748,483,022 - 48,636,151 (+)EnsemblGRCr8
mRatBN7.2746,596,944 - 46,749,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx748,496,671 - 48,649,451 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,699,816 - 50,852,600 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,477,574 - 50,630,354 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,878,906 - 54,030,110 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)Ensemblrn6Rnor6.0
Rnor_5.0753,888,262 - 54,039,874 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4750,308,713 - 50,313,369 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera743,400,573 - 43,550,915 (+)NCBICelera
Cytogenetic Map7q22NCBI
OSBPL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381276,351,797 - 76,559,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1276,351,797 - 76,559,809 (-)Ensemblhg38GRCh38
GRCh371276,745,577 - 76,953,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,269,708 - 75,477,720 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341275,248,047 - 75,456,057NCBI
Celera1276,411,526 - 76,618,915 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1273,797,739 - 74,006,667 (-)NCBIHuRef
CHM1_11276,711,170 - 76,919,193 (-)NCBICHM1_1
T2T-CHM13v2.01276,329,717 - 76,537,711 (-)NCBIT2T-CHM13v2.0
Osbpl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910111,000,663 - 111,133,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10111,000,613 - 111,133,110 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810111,164,742 - 111,297,249 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10111,164,752 - 111,297,249 (+)Ensemblmm10GRCm38
MGSCv3710110,601,858 - 110,734,303 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610110,568,912 - 110,701,357 (+)NCBIMGSCv36mm8
Celera10113,097,050 - 113,230,968 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1058.24NCBI
Osbpl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540515,577,003 - 15,728,983 (-)Ensembl
ChiLan1.0NW_00495540515,577,003 - 15,728,983 (-)NCBIChiLan1.0ChiLan1.0
OSBPL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21084,386,348 - 84,594,367 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11284,382,738 - 84,590,772 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01273,870,094 - 74,078,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11276,720,276 - 76,927,919 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1276,720,276 - 76,820,830 (-)EnsemblpanPan2panpan1.1
OSBPL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,339,385 - 19,441,583 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,142,987 - 19,637,708 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1519,824,481 - 19,967,789 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01519,678,921 - 19,822,002 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1519,678,364 - 19,822,062 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,279,309 - 19,422,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,337,403 - 19,480,483 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,465,384 - 19,608,478 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Osbpl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,920,929 - 41,081,896 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365684,646,426 - 4,806,308 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365684,646,409 - 4,806,283 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSBPL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl539,568,150 - 39,744,642 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1539,568,136 - 39,744,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2543,258,249 - 43,435,452 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OSBPL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11171,927,862 - 72,142,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1171,927,688 - 72,141,587 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037173,404,092 - 173,620,551 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osbpl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475021,569,352 - 21,757,660 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Osbpl8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11189,309,249 - 189,468,266 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Osbpl8
1251 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:126
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000058589
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74299622658678836Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
D7Rat147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,599,531 - 46,599,681 (+)MAPPERmRatBN7.2
Rnor_6.0753,881,455 - 53,881,604NCBIRnor6.0
Rnor_5.0753,890,984 - 53,891,133UniSTSRnor5.0
RGSC_v3.4750,163,959 - 50,164,849RGDRGSC3.4
RGSC_v3.4750,164,660 - 50,164,809UniSTSRGSC3.4
RGSC_v3.4750,164,126 - 50,164,809UniSTSRGSC3.4
RGSC_v3.1750,185,102 - 50,185,251RGD
RH 3.4 Map7394.4RGD
RH 3.4 Map7394.4UniSTS
RH 2.0 Map7361.8RGD
SHRSP x BN Map729.74RGD
Cytogenetic Map7q21UniSTS
D7Uwm11  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8748,482,151 - 48,482,307 (+)Marker Load Pipeline
mRatBN7.2746,595,874 - 46,596,030 (+)MAPPERmRatBN7.2
Rnor_6.0753,877,799 - 53,877,954NCBIRnor6.0
Rnor_5.0753,887,328 - 53,887,483UniSTSRnor5.0
RGSC_v3.4750,160,469 - 50,160,625RGDRGSC3.4
RGSC_v3.4750,160,470 - 50,160,625UniSTSRGSC3.4
Celera743,399,467 - 43,399,621UniSTS
RGSC_v3.1750,180,911 - 50,181,067RGD
Cytogenetic Map7q21UniSTS
RH130422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,749,378 - 46,749,592 (+)MAPPERmRatBN7.2
Rnor_6.0754,029,601 - 54,029,814NCBIRnor6.0
Rnor_5.0754,167,511 - 54,167,724UniSTSRnor5.0
Rnor_5.0754,039,365 - 54,039,578UniSTSRnor5.0
RGSC_v3.4750,316,140 - 50,316,353UniSTSRGSC3.4
Celera743,550,406 - 43,550,619UniSTS
RH 3.4 Map7391.0UniSTS
Cytogenetic Map7q21UniSTS
BF405318  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map7387.8UniSTS
Cytogenetic Map7q21UniSTS
AU047198  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0753,908,202 - 53,908,380NCBIRnor6.0
Rnor_5.0753,917,966 - 53,918,144UniSTSRnor5.0
RGSC_v3.4750,191,528 - 50,191,706UniSTSRGSC3.4
Celera743,429,059 - 43,429,237UniSTS
Cytogenetic Map7q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000058589   ⟹   ENSRNOP00000055387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl754,021,832 - 54,026,789 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091910   ⟹   ENSRNOP00000070347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,483,237 - 48,636,151 (+)Ensembl
mRatBN7.2 Ensembl746,596,983 - 46,749,888 (+)Ensembl
Rnor_6.0 Ensembl753,878,610 - 54,027,892 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097311   ⟹   ENSRNOP00000085965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,483,022 - 48,636,149 (+)Ensembl
mRatBN7.2 Ensembl746,648,508 - 46,749,888 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100604   ⟹   ENSRNOP00000085930
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,575,227 - 48,636,151 (+)Ensembl
mRatBN7.2 Ensembl746,689,051 - 46,749,888 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101432   ⟹   ENSRNOP00000090337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,570,533 - 48,636,151 (+)Ensembl
mRatBN7.2 Ensembl746,684,097 - 46,749,888 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112719   ⟹   ENSRNOP00000079217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,558,274 - 48,636,151 (+)Ensembl
mRatBN7.2 Ensembl746,672,009 - 46,749,888 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146805   ⟹   ENSRNOP00000108245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,626,323 - 48,632,335 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172692   ⟹   ENSRNOP00000101027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,627,913 - 48,632,829 (+)Ensembl
RefSeq Acc Id: NM_001309455   ⟹   NP_001296384
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,483,259 - 48,636,151 (+)NCBI
mRatBN7.2746,596,983 - 46,749,888 (+)NCBI
Rnor_6.0753,878,906 - 54,030,110 (+)NCBI
Celera743,400,573 - 43,550,915 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594846   ⟹   XP_017450335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,564,409 - 48,636,151 (+)NCBI
mRatBN7.2746,684,570 - 46,749,888 (+)NCBI
Rnor_6.0753,969,162 - 54,030,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263481   ⟹   XP_063119551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,533,629 - 48,636,151 (+)NCBI
RefSeq Acc Id: NP_001296384   ⟸   NM_001309455
- UniProtKB: A0A0G2JXN8 (UniProtKB/TrEMBL),   A6IGF8 (UniProtKB/TrEMBL),   A0A8I6A2N1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450335   ⟸   XM_017594846
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GDH8 (UniProtKB/TrEMBL),   A0A8I6ADC9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000055387   ⟸   ENSRNOT00000058589
Ensembl Acc Id: ENSRNOP00000070347   ⟸   ENSRNOT00000091910
Ensembl Acc Id: ENSRNOP00000090337   ⟸   ENSRNOT00000101432
Ensembl Acc Id: ENSRNOP00000085930   ⟸   ENSRNOT00000100604
Ensembl Acc Id: ENSRNOP00000079217   ⟸   ENSRNOT00000112719
Ensembl Acc Id: ENSRNOP00000085965   ⟸   ENSRNOT00000097311
RefSeq Acc Id: XP_063119551   ⟸   XM_063263481
- Peptide Label: isoform X2
- UniProtKB: A6IGG0 (UniProtKB/TrEMBL),   A0A8I6A2N1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108245   ⟸   ENSRNOT00000146805
Ensembl Acc Id: ENSRNOP00000101027   ⟸   ENSRNOT00000172692
Protein Domains
PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JXN8-F1-model_v2 AlphaFold A0A0G2JXN8 1-888 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695196
Promoter ID:EPDNEW_R5713
Type:initiation region
Name:Osbpl8_1
Description:oxysterol binding protein-like 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0753,878,688 - 53,878,748EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561474 AgrOrtholog
BioCyc Gene G2FUF-34130 BioCyc
Ensembl Genes ENSRNOG00000026962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091910.3 UniProtKB/TrEMBL
  ENSRNOT00000097311 ENTREZGENE
  ENSRNOT00000097311.2 UniProtKB/TrEMBL
  ENSRNOT00000100604 ENTREZGENE
  ENSRNOT00000100604.2 UniProtKB/TrEMBL
  ENSRNOT00000101432.2 UniProtKB/TrEMBL
  ENSRNOT00000112719 ENTREZGENE
  ENSRNOT00000112719.2 UniProtKB/TrEMBL
  ENSRNOT00000146805.1 UniProtKB/TrEMBL
  ENSRNOT00000172692.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2720 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.40.160.120 UniProtKB/TrEMBL
  3.30.70.3490 UniProtKB/TrEMBL
InterPro OSBP_sf UniProtKB/TrEMBL
  Oxysterol-bd UniProtKB/TrEMBL
  Oxysterol-bd_CS UniProtKB/TrEMBL
  PH/PTB_dom UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
KEGG Report rno:314824 UniProtKB/TrEMBL
NCBI Gene 314824 ENTREZGENE
PANTHER OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 8 UniProtKB/TrEMBL
  PTHR10972 UniProtKB/TrEMBL
Pfam Oxysterol_BP UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Osbpl8 PhenoGen
PROSITE OSBP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026962 RatGTEx
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF144000 UniProtKB/TrEMBL
UniProt A0A0G2JXN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMZ6_RAT UniProtKB/TrEMBL
  A0A8I6A2N1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GDH8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L7Q8_RAT UniProtKB/TrEMBL
  A6IGF8 ENTREZGENE, UniProtKB/TrEMBL
  A6IGG0 ENTREZGENE, UniProtKB/TrEMBL
  B5DF26_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Osbpl8  oxysterol binding protein-like 8  RGD1561474  similar to oxysterol-binding protein-like protein 8 isoform a  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561474  similar to oxysterol-binding protein-like protein 8 isoform a   RGD1561474_predicted  similar to oxysterol-binding protein-like protein 8 isoform a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561474_predicted  similar to oxysterol-binding protein-like protein 8 isoform a (predicted)  LOC314824  similar to oxysterol-binding protein-like protein 8 isoform a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC314824  similar to oxysterol-binding protein-like protein 8 isoform a      Symbol and Name status set to provisional 70820 PROVISIONAL