Mgst3l1 (microsomal glutathione S-transferase 3 like 1) - Rat Genome Database

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Gene: Mgst3l1 (microsomal glutathione S-transferase 3 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mgst3l1 (Ensembl: Utp3)
Name: microsomal glutathione S-transferase 3 like 1 (Ensembl:UTP3, small subunit processome component)
RGD ID: 1561381
Description: Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human MGST3 (microsomal glutathione S-transferase 3); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutathione S-transferase 3, mitochondrial-like; LOC498340; microsomal glutathione S-transferase 3-like; RGD1561381; similar to microsomal glutathione S-transferase 3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,809,202 - 19,811,522 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1419,793,864 - 19,812,376 (+)EnsemblGRCr8
mRatBN7.21419,525,509 - 19,526,128 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,525,558 - 19,526,016 (+)EnsemblmRatBN7.2
Rnor_6.01421,163,791 - 21,164,435 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01421,073,611 - 21,074,255 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41421,105,801 - 21,106,259 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1418,864,156 - 18,864,800 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Mgst3l1
36 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:42
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000004798
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141787564536079022Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 12 44 26 82 48 11 43 27 16 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004787   ⟹   ENSRNOP00000004787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1419,799,699 - 19,812,376 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000004798   ⟹   ENSRNOP00000096456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1419,793,864 - 19,810,179 (+)Ensembl
mRatBN7.2 Ensembl1419,525,558 - 19,526,016 (+)Ensembl
Rnor_6.0 Ensembl1421,163,840 - 21,164,295 (+)Ensembl
RefSeq Acc Id: XM_063273814   ⟹   XP_063129884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,809,202 - 19,811,522 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063129884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004787
  ENSRNOP00000096456.1
Ensembl Acc Id: ENSRNOP00000096456   ⟸   ENSRNOT00000004798
RefSeq Acc Id: XP_063129884   ⟸   XM_063273814
- UniProtKB: A0A8I6AQS8 (UniProtKB/TrEMBL),   A0A8I6AAX9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000004787   ⟸   ENSRNOT00000004787

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561381 AgrOrtholog
BioCyc Gene G2FUF-16161 BioCyc
Ensembl Genes ENSRNOG00000003599 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000003606 Ensembl
Ensembl Transcript ENSRNOT00000004787 ENTREZGENE
  ENSRNOT00000004798.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/TrEMBL
InterPro MAPEG UniProtKB/TrEMBL
  MAPEG-like_dom_sf UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/TrEMBL
NCBI Gene 498340 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/TrEMBL
PhenoGen Mgst3l1 PhenoGen
RatGTEx ENSRNOG00000003599 RatGTEx
  ENSRNOG00000003606 RatGTEx
Superfamily-SCOP SSF161084 UniProtKB/TrEMBL
UniProt A0A8I6AAX9 ENTREZGENE
  A0A8I6AQS8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Mgst3l1  microsomal glutathione S-transferase 3 like 1  RGD1561381  similar to microsomal glutathione S-transferase 3  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1561381  similar to microsomal glutathione S-transferase 3   RGD1561381_predicted  similar to microsomal glutathione S-transferase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561381_predicted  similar to microsomal glutathione S-transferase 3 (predicted)  LOC498340  similar to microsomal glutathione S-transferase 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498340  similar to microsomal glutathione S-transferase 3      Symbol and Name status set to provisional 70820 PROVISIONAL