Fam167a (family with sequence similarity 167, member A) - Rat Genome Database

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Gene: Fam167a (family with sequence similarity 167, member A) Rattus norvegicus
Analyze
Symbol: Fam167a
Name: family with sequence similarity 167, member A
RGD ID: 1561302
Description: Orthologous to human FAM167A (family with sequence similarity 167 member A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC498533; LOC498533; RGD1561302; similar to Hypothetical protein A030013D21; uncharacterized protein LOC498533
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,861,271 - 41,891,427 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,861,227 - 41,891,418 (+)EnsemblGRCr8
mRatBN7.21537,685,221 - 37,715,472 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,700,919 - 37,715,469 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1539,553,577 - 39,568,079 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,704,376 - 40,718,880 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,161,540 - 39,176,088 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,613,761 - 46,643,771 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,613,810 - 46,643,772 (+)Ensemblrn6Rnor6.0
Rnor_5.01550,391,387 - 50,405,856 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41542,719,193 - 42,734,086 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1537,384,033 - 37,398,670 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Fam167a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,861,271 - 41,891,427 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,861,227 - 41,891,418 (+)EnsemblGRCr8
mRatBN7.21537,685,221 - 37,715,472 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,700,919 - 37,715,469 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1539,553,577 - 39,568,079 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,704,376 - 40,718,880 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,161,540 - 39,176,088 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,613,761 - 46,643,771 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,613,810 - 46,643,772 (+)Ensemblrn6Rnor6.0
Rnor_5.01550,391,387 - 50,405,856 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41542,719,193 - 42,734,086 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1537,384,033 - 37,398,670 (+)NCBICelera
Cytogenetic Map15p12NCBI
FAM167A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38811,421,476 - 11,475,908 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl811,421,463 - 11,475,908 (-)Ensemblhg38GRCh38
GRCh37811,278,985 - 11,324,262 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36811,316,382 - 11,361,663 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34811,316,381 - 11,361,663NCBI
Celera810,407,815 - 10,453,655 (-)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef810,209,873 - 10,255,620 (-)NCBIHuRef
CHM1_1811,342,675 - 11,389,545 (-)NCBICHM1_1
T2T-CHM13v2.088,264,329 - 8,319,261 (+)NCBIT2T-CHM13v2.0
Fam167a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,673,843 - 63,702,951 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1463,673,843 - 63,702,947 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381463,436,394 - 63,465,502 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,436,394 - 63,465,498 (+)Ensemblmm10GRCm38
MGSCv371464,055,231 - 64,084,339 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361462,390,565 - 62,419,608 (+)NCBIMGSCv36mm8
Celera1461,201,823 - 61,231,274 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.28NCBI
Fam167a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,774,966 - 52,800,378 (-)Ensembl
ChiLan1.0NW_00495540352,775,004 - 52,805,452 (-)NCBIChiLan1.0ChiLan1.0
FAM167A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2727,888,518 - 27,934,406 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan183,914,802 - 3,960,791 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v087,735,764 - 7,781,696 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FAM167A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12526,437,250 - 26,485,177 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2526,447,271 - 26,485,185 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2527,093,066 - 27,137,791 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02526,590,756 - 26,635,472 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2526,600,794 - 26,638,477 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12526,543,425 - 26,590,329 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02526,440,541 - 26,485,460 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02526,592,254 - 26,637,409 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fam167a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049435,417,729 - 5,448,297 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366753,137,556 - 3,168,213 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366753,137,886 - 3,168,330 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM167A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1414,627,230 - 14,667,455 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11414,627,242 - 14,667,494 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FAM167A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.187,644,276 - 7,689,571 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl87,666,432 - 7,689,746 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605234,738,505 - 34,784,756 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam167a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475825,087,870 - 25,103,589 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475825,087,788 - 25,114,556 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fam167a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11260,929,312 - 60,956,195 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fam167a
42 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:318
Count of miRNA genes:193
Interacting mature miRNAs:240
Transcripts:ENSRNOT00000015055
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 162 91 90 59 74 59 6 334 173 11 139 78 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015055   ⟹   ENSRNOP00000015055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,861,227 - 41,891,418 (+)Ensembl
mRatBN7.2 Ensembl1537,700,919 - 37,715,469 (+)Ensembl
Rnor_6.0 Ensembl1546,613,810 - 46,643,772 (+)Ensembl
RefSeq Acc Id: NM_001109102   ⟹   NP_001102572
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,876,868 - 41,891,416 (+)NCBI
mRatBN7.21537,700,919 - 37,715,469 (+)NCBI
Rnor_6.01546,629,230 - 46,643,770 (+)NCBI
Rnor_5.01550,391,387 - 50,405,856 (+)NCBI
RGSC_v3.41542,719,193 - 42,734,086 (+)RGD
Celera1537,384,033 - 37,398,670 (+)RGD
Sequence:
RefSeq Acc Id: XM_008770771   ⟹   XP_008768993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,861,271 - 41,891,427 (+)NCBI
mRatBN7.21537,685,221 - 37,715,472 (+)NCBI
Rnor_6.01546,613,761 - 46,643,771 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063274552   ⟹   XP_063130622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,875,716 - 41,891,427 (+)NCBI
RefSeq Acc Id: XM_063274553   ⟹   XP_063130623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,861,345 - 41,883,532 (+)NCBI
RefSeq Acc Id: NP_001102572   ⟸   NM_001109102
- UniProtKB: D3ZQX1 (UniProtKB/TrEMBL),   A6K6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768993   ⟸   XM_008770771
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000015055   ⟸   ENSRNOT00000015055
RefSeq Acc Id: XP_063130623   ⟸   XM_063274553
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130622   ⟸   XM_063274552
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQX1-F1-model_v2 AlphaFold D3ZQX1 1-215 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699778
Promoter ID:EPDNEW_R10300
Type:single initiation site
Name:Fam167a_1
Description:family with sequence similarity 167, member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01546,613,784 - 46,613,844EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561302 AgrOrtholog
BioCyc Gene G2FUF-13422 BioCyc
Ensembl Genes ENSRNOG00000011316 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015055 ENTREZGENE
  ENSRNOT00000015055.6 UniProtKB/TrEMBL
InterPro FAM167 UniProtKB/TrEMBL
  FAM167_domain UniProtKB/TrEMBL
KEGG Report rno:498533 UniProtKB/TrEMBL
NCBI Gene 498533 ENTREZGENE
PANTHER PROTEIN FAM167A UniProtKB/TrEMBL
  PROTEIN FAM167A UniProtKB/TrEMBL
Pfam DUF3259 UniProtKB/TrEMBL
PhenoGen Fam167a PhenoGen
RatGTEx ENSRNOG00000011316 RatGTEx
UniProt A6K6G2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQX1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Fam167a  family with sequence similarity 167, member A  RGD1561302  similar to Hypothetical protein A030013D21   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561302  similar to Hypothetical protein A030013D21   RGD1561302_predicted  similar to Hypothetical protein A030013D21 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561302_predicted  similar to Hypothetical protein A030013D21 (predicted)  LOC498533  similar to Hypothetical protein A030013D21  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498533  similar to Hypothetical protein A030013D21      Symbol and Name status set to provisional 70820 PROVISIONAL