Vom2r30 (vomeronasal 2 receptor, 30) - Rat Genome Database

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Gene: Vom2r30 (vomeronasal 2 receptor, 30) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r30 (Ensembl: AABR07002473.1)
Name: vomeronasal 2 receptor, 30
RGD ID: 1561133
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH ammonium chloride.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC289295; RGD1561133; similar to putative pheromone receptor (Go-VN2); vomeronasal 2 receptor 30
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8180,056,615 - 80,079,112 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2170,984,426 - 71,006,924 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl170,984,379 - 71,007,229 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx176,372,796 - 76,395,301 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0184,937,111 - 84,959,617 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,055,741 - 78,078,206 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0174,770,009 - 74,791,415 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0173,764,568 - 73,786,425 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4170,452,168 - 70,474,845 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera166,126,702 - 66,149,120 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r30
132 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

mesenchyme
renal system
1 1

Sequence


Ensembl Acc Id: ENSRNOT00000012225   ⟹   ENSRNOP00000012225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl170,984,379 - 71,007,229 (+)Ensembl
RefSeq Acc Id: NM_001099467   ⟹   NP_001092937
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8180,056,615 - 80,079,112 (+)NCBI
mRatBN7.2170,984,426 - 71,006,924 (+)NCBI
Rnor_6.0174,770,009 - 74,791,415 (+)NCBI
Rnor_5.0173,764,568 - 73,786,425 (-)NCBI
RGSC_v3.4170,452,168 - 70,474,845 (+)RGD
Celera166,126,702 - 66,149,120 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102819   ⟹   XP_038958747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8180,056,615 - 80,079,112 (+)NCBI
mRatBN7.2170,984,426 - 71,006,924 (+)NCBI
RefSeq Acc Id: XM_039102821   ⟹   XP_038958749
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8180,056,615 - 80,079,112 (+)NCBI
mRatBN7.2170,984,426 - 71,006,924 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001092937 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958747 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958749 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012225.8
  ENSRNOP00000069490
  ENSRNOP00000069490.3
RefSeq Acc Id: NP_001092937   ⟸   NM_001099467
- Peptide Label: precursor
- UniProtKB: F1LVC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038958749   ⟸   XM_039102821
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958747   ⟸   XM_039102819
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000012225   ⟸   ENSRNOT00000012225

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LVC2-F1-model_v2 AlphaFold F1LVC2 1-849 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561133 AgrOrtholog
BioCyc Gene G2FUF-60799 BioCyc
Ensembl Genes ENSRNOG00000046339 Ensembl
  ENSRNOG00000083361 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000085157 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012225.8 UniProtKB/TrEMBL
  ENSRNOT00000090708 ENTREZGENE
  ENSRNOT00000090708.3 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
KEGG Report rno:289295 UniProtKB/TrEMBL
NCBI Gene 289295 ENTREZGENE
PANTHER EC2-V2R PHEROMONE RECEPTOR PROTEIN-RELATED UniProtKB/TrEMBL
  PTHR24061 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r30 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046339 RatGTEx
  ENSRNOG00000083361 RatGTEx
  ENSRNOG00000085157 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A0G2JVH8_RAT UniProtKB/TrEMBL
  F1LVC2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r30  vomeronasal 2 receptor, 30  RGD1561133  similar to putative pheromone receptor (Go-VN2)   Symbol and Name updated 1299863 APPROVED
2008-04-30 RGD1561133  similar to putative pheromone receptor (Go-VN2)   RGD1561133_predicted  similar to putative pheromone receptor (Go-VN2) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561133_predicted  similar to putative pheromone receptor (Go-VN2) (predicted)  LOC289295  similar to putative pheromone receptor (Go-VN2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289295  similar to putative pheromone receptor (Go-VN2)      Symbol and Name status set to provisional 70820 PROVISIONAL