Wdr95 (WD40 repeat domain 95) - Rat Genome Database

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Gene: Wdr95 (WD40 repeat domain 95) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Wdr95
Name: WD40 repeat domain 95
RGD ID: 1561029
Description:
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box and WD repeat domain containing 7-like; LOC304252; RGD1561029; similar to RIKEN cDNA 4930434E21; WD repeat-containing protein 49-like; WD repeat-containing protein on Y chromosome-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,452,187 - 10,502,622 (-)NCBIGRCr8
mRatBN7.2125,415,815 - 5,466,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl125,415,524 - 5,556,766 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0126,265,417 - 6,317,097 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl126,265,748 - 6,316,948 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0128,366,075 - 8,417,958 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera127,187,491 - 7,316,645 (-)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Wdr95
376 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:90
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000001203, ENSRNOT00000061252
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
724526Uae3Urinary albumin excretion QTL 34.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)12390696910373166Rat

Markers in Region
D12Got6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2125,433,024 - 5,433,143 (-)MAPPERmRatBN7.2
Rnor_6.0126,299,727 - 6,300,789NCBIRnor6.0
Rnor_5.0128,401,084 - 8,401,203NCBIRnor5.0
RGSC_v3.4125,834,925 - 5,835,110UniSTSRGSC3.4
RGSC_v3.4125,834,924 - 5,835,110RGDRGSC3.4
RGSC_v3.1125,834,925 - 5,835,110RGD
Celera127,203,876 - 7,204,061UniSTS
RH 3.4 Map1250.5RGD
RH 3.4 Map1250.5UniSTS
RH 2.0 Map1264.4RGD


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system renal system reproductive system respiratory system
High
Medium 4
Low 1 24 11
Below cutoff 1 3 4 2 2 2 33 3 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001203   ⟹   ENSRNOP00000001203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,415,524 - 5,556,766 (-)Ensembl
Rnor_6.0 Ensembl126,283,288 - 6,303,753 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000061252   ⟹   ENSRNOP00000057964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl125,415,524 - 5,467,080 (-)Ensembl
Rnor_6.0 Ensembl126,265,748 - 6,316,948 (+)Ensembl
RefSeq Acc Id: XM_039089920   ⟹   XP_038945848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81210,452,187 - 10,502,622 (-)NCBI
mRatBN7.2125,415,815 - 5,466,253 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038945848 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001203.8
  ENSRNOP00000057964
  ENSRNOP00000057964.5
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000057964   ⟸   ENSRNOT00000061252
RefSeq Acc Id: ENSRNOP00000001203   ⟸   ENSRNOT00000001203
RefSeq Acc Id: XP_038945848   ⟸   XM_039089920
- UniProtKB: F1M3H0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M3H0-F1-model_v2 AlphaFold F1M3H0 1-629 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561029 AgrOrtholog
BioCyc Gene G2FUF-20202 BioCyc
Ensembl Genes ENSRNOG00000000904 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001203.8 UniProtKB/TrEMBL
  ENSRNOT00000061252.6 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Wdr95 ENTREZGENE
PANTHER WD40 REPEAT DOMAIN 95 UniProtKB/TrEMBL
  WD40 REPEAT DOMAIN 95 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Wdr95 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000904 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt D3ZTT3_RAT UniProtKB/TrEMBL
  F1M3H0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-11 Wdr95  WD40 repeat domain 95  RGD1561029  similar to RIKEN cDNA 4930434E21  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-02 RGD1561029  similar to RIKEN cDNA 4930434E21  LOC100361588  F-box and WD repeat domain containing 7-like  Data merged from RGD:2319881 1643240 APPROVED
2010-05-05 LOC100361588  F-box and WD repeat domain containing 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1561029  similar to RIKEN cDNA 4930434E21   RGD1561029_predicted  similar to RIKEN cDNA 4930434E21 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561029_predicted  similar to RIKEN cDNA 4930434E21 (predicted)  LOC304252  similar to RIKEN cDNA 4930434E21  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC304252  similar to RIKEN cDNA 4930434E21      Symbol and Name status set to provisional 70820 PROVISIONAL