Rfk-ps3 (riboflavin kinase, pseudogene 3) - Rat Genome Database

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Gene: Rfk-ps3 (riboflavin kinase, pseudogene 3) Rattus norvegicus
Analyze
Symbol: Rfk-ps3 (Ensembl: AABR07053065.1)
Name: riboflavin kinase, pseudogene 3 (Ensembl:riboflavin kinase, pseudo 3)
RGD ID: 1560961
Description: Predicted to enable ATP binding activity; metal ion binding activity; and riboflavin kinase activity. Predicted to be involved in FMN biosynthetic process and riboflavin biosynthetic process; INTERACTS WITH nefazodone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC311241; RGD1560961; riboflavin kinase-like; similar to RIKEN cDNA 0610038L10 gene
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83106,965,232 - 106,967,412 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3106,954,321 - 106,967,418 (-)EnsemblGRCr8
mRatBN7.2386,510,729 - 86,512,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl386,511,659 - 86,512,126 (-)EnsemblmRatBN7.2
Rnor_6.0389,743,733 - 89,745,868 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0396,410,125 - 96,412,295 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4385,344,977 - 85,346,284 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera385,630,517 - 85,632,652 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
nefazodone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rfk-ps3
6 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
RH129140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,806,001 - 214,806,151 (-)MAPPERmRatBN7.2
mRatBN7.2386,511,414 - 86,511,564 (+)MAPPERmRatBN7.2
Rnor_6.01236,495,462 - 236,495,611NCBIRnor6.0
Rnor_6.0389,744,994 - 89,745,143NCBIRnor6.0
Rnor_5.0396,411,386 - 96,411,535UniSTSRnor5.0
Rnor_5.01243,799,992 - 243,800,141UniSTSRnor5.0
RGSC_v3.41220,930,669 - 220,930,818UniSTSRGSC3.4
RGSC_v3.4385,345,573 - 85,345,722UniSTSRGSC3.4
Celera385,631,778 - 85,631,927UniSTS
Celera1212,121,716 - 212,121,865UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map3q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 17 43 51 112 70 2 49 35 27 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005784   ⟹   ENSRNOP00000078651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3106,954,321 - 106,967,418 (-)Ensembl
mRatBN7.2 Ensembl386,511,659 - 86,512,126 (-)Ensembl
RefSeq Acc Id: XM_063285285   ⟹   XP_063141355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83106,965,232 - 106,967,412 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063141355 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078651
  ENSRNOP00000078651.1
RefSeq Acc Id: XP_063141355   ⟸   XM_063285285
- UniProtKB: A0A8I5ZLE0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078651   ⟸   ENSRNOT00000005784
Protein Domains
Riboflavin kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-48619 BioCyc
Ensembl Genes ENSRNOG00000004381 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005784 ENTREZGENE
  ENSRNOT00000005784.9 UniProtKB/TrEMBL
Gene3D-CATH Riboflavin kinase-like UniProtKB/TrEMBL
InterPro Riboflavin_kinase UniProtKB/TrEMBL
  Riboflavin_kinase_bac/euk UniProtKB/TrEMBL
  Riboflavin_kinase_dom_sf UniProtKB/TrEMBL
NCBI Gene 311241 ENTREZGENE
PANTHER RIBOFLAVIN KINASE UniProtKB/TrEMBL
  RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE UniProtKB/TrEMBL
Pfam Flavokinase UniProtKB/TrEMBL
PhenoGen Rfk-ps3 PhenoGen
RatGTEx ENSRNOG00000004381 RatGTEx
SMART Flavokinase UniProtKB/TrEMBL
Superfamily-SCOP Riboflavin kinase-like UniProtKB/TrEMBL
UniProt A0A8I5ZLE0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Rfk-ps3  riboflavin kinase, pseudogene 3  RGD1560961  similar to RIKEN cDNA 0610038L10 gene  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560961  similar to RIKEN cDNA 0610038L10 gene   RGD1560961_predicted  similar to RIKEN cDNA 0610038L10 gene (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560961_predicted  similar to RIKEN cDNA 0610038L10 gene (predicted)  LOC311241  similar to RIKEN cDNA 0610038L10 gene  Symbol and Name status set to approved 1299863 APPROVED