Mageb2 (MAGE family member B2) - Rat Genome Database

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Gene: Mageb2 (MAGE family member B2) Rattus norvegicus
Analyze
Symbol: Mageb2
Name: MAGE family member B2
RGD ID: 1560904
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MAGEB2 (MAGE family member B2); INTERACTS WITH bisphenol A; 5-aza-2'-deoxycytidine (ortholog); 5-fluorouracil (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102553413; LOC302744; Mageb1; melanoma antigen family B, 1; melanoma antigen family B, 2; melanoma-associated antigen B2; melanoma-associated antigen B2-like; melanoma-associated antigen B4; RGD1560904; similar to melanoma antigen family B, 2; uncharacterized LOC102553413
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,778,318 - 54,784,040 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)EnsemblmRatBN7.2
Rnor_6.0X54,807,024 - 54,811,144 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X55,008,041 - 55,009,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X73,077,761 - 73,079,281 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX51,363,308 - 51,368,908 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10706124  


Genomics

Comparative Map Data
Mageb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,778,318 - 54,784,040 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)EnsemblmRatBN7.2
Rnor_6.0X54,807,024 - 54,811,144 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X55,008,041 - 55,009,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X73,077,761 - 73,079,281 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX51,363,308 - 51,368,908 (-)NCBICelera
Cytogenetic MapXq21NCBI
MAGEB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,215,563 - 30,220,089 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX30,215,563 - 30,220,089 (+)Ensemblhg38GRCh38
GRCh37X30,233,680 - 30,238,206 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,143,601 - 30,148,127 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X29,993,336 - 29,997,861NCBI
CeleraX34,355,297 - 34,359,830 (+)NCBICelera
Cytogenetic MapXp21.2NCBI
HuRefX27,970,706 - 27,975,164 (+)NCBIHuRef
CHM1_1X30,264,618 - 30,269,149 (+)NCBICHM1_1
T2T-CHM13v2.0X29,807,905 - 29,812,440 (+)NCBIT2T-CHM13v2.0
Mageb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X85,293,862 - 85,299,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX85,293,860 - 85,348,699 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X86,250,256 - 86,256,219 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX86,250,254 - 86,305,093 (-)Ensemblmm10GRCm38
MGSCv37X83,495,595 - 83,501,558 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X82,502,979 - 82,508,938 (-)NCBIMGSCv36mm8
CeleraX77,496,548 - 77,498,783 (-)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.71NCBI
MAGEB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X31,999,839 - 32,005,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X32,003,219 - 32,008,904 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X22,804,983 - 22,810,236 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X30,366,930 - 30,371,454 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX30,369,947 - 30,370,906 (+)EnsemblpanPan2panpan1.1
LOC102159844
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X25,895,424 - 26,030,203 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X28,112,653 - 28,296,432 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAGEB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X28,619,651 - 28,624,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX28,622,915 - 28,623,862 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605630,605,109 - 30,609,010 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Mageb2
7 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

circulatory system
mesenchyme
mesoderm
reproductive system
1 1 1 2

Sequence


Ensembl Acc Id: ENSRNOT00000050661   ⟹   ENSRNOP00000090919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX50,827,563 - 50,833,151 (-)Ensembl
RefSeq Acc Id: XM_039100331   ⟹   XP_038956259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,784,040 (-)NCBI
mRatBN7.2X50,827,538 - 50,833,272 (-)NCBI
RefSeq Acc Id: XM_063280373   ⟹   XP_063136443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,784,040 (-)NCBI
RefSeq Acc Id: XM_063280374   ⟹   XP_063136444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X54,778,318 - 54,783,404 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001420282 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956259 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136443 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136444 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96045 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_038956259   ⟸   XM_039100331
- UniProtKB: A0A8I6AAL9 (UniProtKB/TrEMBL),   A6IPW8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090919   ⟸   ENSRNOT00000050661
RefSeq Acc Id: XP_063136443   ⟸   XM_063280373
- UniProtKB: A0A8I6AAL9 (UniProtKB/TrEMBL),   A6IPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136444   ⟸   XM_063280374
Protein Domains
MAGE

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560904 AgrOrtholog
Ensembl Genes ENSRNOG00000028179 Ensembl
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene Mageb2 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B1 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb2 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028179 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A0A8I6AAL9 ENTREZGENE
  A6IPW8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mageb2  MAGE family member B2  LOC102553413  uncharacterized LOC102553413  Data merged from RGD:7610508 737654 PROVISIONAL
2015-12-16 Mageb2  MAGE family member B2  Mageb2  melanoma antigen family B, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102553413  uncharacterized LOC102553413      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-02-18 Mageb2  melanoma antigen family B, 2  Mageb1  melanoma antigen family B, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Mageb1  melanoma antigen family B, 1  RGD1560904  similar to melanoma antigen family B, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560904  similar to melanoma antigen family B, 2   RGD1560904_predicted  similar to melanoma antigen family B, 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560904_predicted  similar to melanoma antigen family B, 2 (predicted)  LOC302744  similar to melanoma antigen family B, 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302744  similar to melanoma antigen family B, 2      Symbol and Name status set to provisional 70820 PROVISIONAL