Cysrt1 (cysteine rich tail 1) - Rat Genome Database

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Gene: Cysrt1 (cysteine rich tail 1) Rattus norvegicus
Analyze
Symbol: Cysrt1
Name: cysteine rich tail 1
RGD ID: 1560880
Description: Predicted to enable identical protein binding activity. Predicted to be involved in biological process involved in interaction with symbiont and establishment of skin barrier. Predicted to be located in cornified envelope. Orthologous to human CYSRT1 (cysteine rich tail 1); INTERACTS WITH bisphenol A; cadmium dichloride; poly(I:C).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cysteine-rich tail protein 1; hypothetical protein LOC499747; LOC499747; RGD1560880; similar to RIKEN cDNA 2310002J15; uncharacterized protein LOC499747; UPF0574 protein C9orf169 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,452,359 - 28,456,006 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,451,219 - 28,456,118 (-)EnsemblGRCr8
mRatBN7.238,054,195 - 8,057,846 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,053,482 - 8,059,721 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,158,910 - 11,160,000 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,745,139 - 19,746,229 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,934,982 - 17,936,072 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,458,295 - 2,462,037 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,458,295 - 2,459,385 (-)Ensemblrn6Rnor6.0
Rnor_5.032,439,578 - 2,440,668 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,403,404 - 3,404,494 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera32,880,834 - 2,881,924 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19056867  


Genomics

Comparative Map Data
Cysrt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,452,359 - 28,456,006 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,451,219 - 28,456,118 (-)EnsemblGRCr8
mRatBN7.238,054,195 - 8,057,846 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,053,482 - 8,059,721 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,158,910 - 11,160,000 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,745,139 - 19,746,229 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,934,982 - 17,936,072 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,458,295 - 2,462,037 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,458,295 - 2,459,385 (-)Ensemblrn6Rnor6.0
Rnor_5.032,439,578 - 2,440,668 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,403,404 - 3,404,494 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera32,880,834 - 2,881,924 (-)NCBICelera
Cytogenetic Map3p13NCBI
CYSRT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,225,174 - 137,226,315 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,225,174 - 137,226,315 (+)Ensemblhg38GRCh38
GRCh379140,119,626 - 140,120,767 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera9110,634,766 - 110,635,885 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,578,904 - 109,580,023 (+)NCBIHuRef
CHM1_19140,268,378 - 140,269,497 (+)NCBICHM1_1
T2T-CHM13v2.09149,462,843 - 149,463,984 (+)NCBIT2T-CHM13v2.0
Cysrt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,128,831 - 25,129,876 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,128,830 - 25,132,464 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38225,238,819 - 25,239,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,238,818 - 25,242,452 (-)Ensemblmm10GRCm38
MGSCv37225,094,339 - 25,095,417 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36225,060,836 - 25,061,906 (-)NCBIMGSCv36mm8
Celera224,966,609 - 24,967,687 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.09NCBI
Cysrt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,223,124 - 5,224,650 (+)Ensembl
ChiLan1.0NW_0049555135,223,124 - 5,224,650 (+)NCBIChiLan1.0ChiLan1.0
CYSRT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,173,382 - 2,176,145 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,173,333 - 2,178,342 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,284,155 - 108,285,850 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,252,943 - 137,254,611 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,252,943 - 137,254,611 (+)EnsemblpanPan2panpan1.1
CYSRT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,447,774 - 48,449,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha947,634,089 - 47,636,084 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0949,308,942 - 49,310,935 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,309,180 - 49,309,605 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,085,344 - 48,087,339 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,384,160 - 48,386,155 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,431,313 - 48,433,308 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cysrt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,606,517 - 202,609,934 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669765,149 - 766,381 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936669765,129 - 768,558 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYSRT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,147,909 - 314,149,153 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYSRT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112963,069 - 964,706 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12963,308 - 963,742 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660584,341,182 - 4,342,875 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cysrt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760730,492 - 731,379 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624760730,245 - 731,559 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cysrt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1511,942,868 - 11,943,538 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cysrt1
17 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:150
Count of miRNA genes:118
Interacting mature miRNAs:129
Transcripts:ENSRNOT00000014080
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
RH128599  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.238,054,267 - 8,054,454 (+)MAPPERmRatBN7.2
Rnor_6.032,458,364 - 2,458,550NCBIRnor6.0
Rnor_5.032,439,647 - 2,439,833UniSTSRnor5.0
RGSC_v3.433,403,473 - 3,403,659UniSTSRGSC3.4
Celera32,880,903 - 2,881,089UniSTS
Cytogenetic Map3p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 53 150 70 69 38 84 38 6 304 161 4 131 81 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014080   ⟹   ENSRNOP00000014080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,451,219 - 28,456,118 (-)Ensembl
mRatBN7.2 Ensembl38,053,482 - 8,059,721 (-)Ensembl
Rnor_6.0 Ensembl32,458,295 - 2,459,385 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107278   ⟹   ENSRNOP00000090431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,452,022 - 28,455,869 (-)Ensembl
mRatBN7.2 Ensembl38,053,625 - 8,057,949 (-)Ensembl
RefSeq Acc Id: NM_001109194   ⟹   NP_001102664
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,452,359 - 28,453,449 (-)NCBI
mRatBN7.238,054,199 - 8,055,289 (-)NCBI
Rnor_6.032,458,295 - 2,459,385 (-)NCBI
Rnor_5.032,439,578 - 2,440,668 (-)NCBI
RGSC_v3.433,403,404 - 3,404,494 (-)RGD
Celera32,880,834 - 2,881,924 (-)RGD
Sequence:
RefSeq Acc Id: XM_017591974   ⟹   XP_017447463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,452,359 - 28,456,006 (-)NCBI
mRatBN7.238,055,199 - 8,057,846 (-)NCBI
Rnor_6.032,458,953 - 2,462,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105653   ⟹   XP_038961581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,452,359 - 28,455,225 (-)NCBI
mRatBN7.238,054,195 - 8,057,474 (-)NCBI
RefSeq Acc Id: XM_063284339   ⟹   XP_063140409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,452,359 - 28,455,225 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001102664 (Get FASTA)   NCBI Sequence Viewer  
  XP_017447463 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961581 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140409 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93626 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014080.6
  ENSRNOP00000090431
  ENSRNOP00000090431.1
RefSeq Acc Id: NP_001102664   ⟸   NM_001109194
- UniProtKB: D4ADR7 (UniProtKB/TrEMBL),   A0A8I6GI68 (UniProtKB/TrEMBL),   A6JT21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447463   ⟸   XM_017591974
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000014080   ⟸   ENSRNOT00000014080
RefSeq Acc Id: XP_038961581   ⟸   XM_039105653
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GI68 (UniProtKB/TrEMBL),   A6JT21 (UniProtKB/TrEMBL),   D4ADR7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090431   ⟸   ENSRNOT00000107278
RefSeq Acc Id: XP_063140409   ⟸   XM_063284339
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GI68 (UniProtKB/TrEMBL),   A6JT21 (UniProtKB/TrEMBL),   D4ADR7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADR7-F1-model_v2 AlphaFold D4ADR7 1-140 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691863
Promoter ID:EPDNEW_R2387
Type:single initiation site
Name:Cysrt1_1
Description:cysteine rich tail 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.032,459,350 - 2,459,410EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560880 AgrOrtholog
BioCyc Gene G2FUF-50471 BioCyc
Ensembl Genes ENSRNOG00000010600 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014080.6 UniProtKB/TrEMBL
  ENSRNOT00000107278 ENTREZGENE
  ENSRNOT00000107278.2 UniProtKB/TrEMBL
InterPro UPF0574 UniProtKB/TrEMBL
KEGG Report rno:499747 UniProtKB/TrEMBL
NCBI Gene 499747 ENTREZGENE
PANTHER CYSTEINE-RICH TAIL PROTEIN 1 UniProtKB/TrEMBL
  PTHR37879 UniProtKB/TrEMBL
Pfam DUF2477 UniProtKB/TrEMBL
PhenoGen Cysrt1 PhenoGen
RatGTEx ENSRNOG00000010600 RatGTEx
UniProt A0A8I6GI68 ENTREZGENE
  A6JT21 ENTREZGENE, UniProtKB/TrEMBL
  D4ADR7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8I6GI68 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Cysrt1  cysteine rich tail 1  Cysrt1  cysteine-rich tail protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-06-06 Cysrt1  cysteine-rich tail protein 1  RGD1560880  similar to RIKEN cDNA 2310002J15  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560880  similar to RIKEN cDNA 2310002J15   RGD1560880_predicted  similar to RIKEN cDNA 2310002J15 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560880_predicted  similar to RIKEN cDNA 2310002J15 (predicted)  LOC499747  similar to RIKEN cDNA 2310002J15  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499747  similar to RIKEN cDNA 2310002J15      Symbol and Name status set to provisional 70820 PROVISIONAL