Krtap7-1 (keratin associated protein 7-1) - Rat Genome Database

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Gene: Krtap7-1 (keratin associated protein 7-1) Rattus norvegicus
Analyze
Symbol: Krtap7-1
Name: keratin associated protein 7-1
RGD ID: 1560879
Description: Orthologous to human KRTAP7-1 (keratin associated protein 7-1); INTERACTS WITH alpha-Zearalanol; bisphenol A; perfluorooctanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363741; RGD1560879; similar to ribosomal protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,226,594 - 42,227,230 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1142,226,594 - 42,227,230 (-)EnsemblGRCr8
mRatBN7.21128,740,387 - 28,741,023 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,740,390 - 28,741,003 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1137,419,843 - 37,420,460 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01130,119,869 - 30,120,486 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01129,289,494 - 29,290,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,640,935 - 29,641,551 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,640,938 - 29,641,551 (-)Ensemblrn6Rnor6.0
Rnor_5.01133,262,628 - 33,263,244 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41129,298,464 - 29,299,080 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1128,432,399 - 28,433,015 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548  


Genomics

Comparative Map Data
Krtap7-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,226,594 - 42,227,230 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1142,226,594 - 42,227,230 (-)EnsemblGRCr8
mRatBN7.21128,740,387 - 28,741,023 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,740,390 - 28,741,003 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1137,419,843 - 37,420,460 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01130,119,869 - 30,120,486 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01129,289,494 - 29,290,111 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,640,935 - 29,641,551 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,640,938 - 29,641,551 (-)Ensemblrn6Rnor6.0
Rnor_5.01133,262,628 - 33,263,244 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41129,298,464 - 29,299,080 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1128,432,399 - 28,433,015 (-)NCBICelera
Cytogenetic Map11q11NCBI
KRTAP7-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,829,039 - 30,829,759 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,829,039 - 30,829,759 (-)Ensemblhg38GRCh38
GRCh372132,201,357 - 32,202,078 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362131,123,228 - 31,123,922 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342131,123,230 - 31,123,798NCBI
Celera2117,384,322 - 17,385,016 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,610,249 - 17,610,942 (-)NCBIHuRef
CHM1_12131,763,225 - 31,763,918 (-)NCBICHM1_1
T2T-CHM13v2.02129,196,682 - 29,197,402 (-)NCBIT2T-CHM13v2.0
Krtap7-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391689,304,591 - 89,305,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1689,304,591 - 89,305,211 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381689,507,703 - 89,508,323 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1689,507,703 - 89,508,323 (-)Ensemblmm10GRCm38
MGSCv371689,507,948 - 89,508,568 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361689,507,947 - 89,508,568 (-)NCBIMGSCv36mm8
Celera1689,706,771 - 89,707,391 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.42NCBI
LOC102011839
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540730,545,079 - 30,553,536 (-)Ensembl
ChiLan1.0NW_00495540730,545,079 - 30,553,536 (-)NCBIChiLan1.0ChiLan1.0
LOC100995842
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22226,943,051 - 26,943,771 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12121,802,054 - 21,802,774 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02117,192,655 - 17,193,363 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12130,576,838 - 30,577,525 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2130,577,234 - 30,577,497 (-)EnsemblpanPan2panpan1.1
KRTAP7-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13125,830,081 - 25,830,799 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3125,830,479 - 25,830,742 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3125,820,540 - 25,821,326 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03125,945,214 - 25,946,000 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3125,945,612 - 25,945,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13125,892,674 - 25,893,460 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03125,904,274 - 25,905,060 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03126,372,341 - 26,373,127 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101966605
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497126,408,706 - 26,409,375 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650011,058,503 - 11,058,751 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650011,058,503 - 11,058,751 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100626483
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13194,457,641 - 194,457,898 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113194,457,340 - 194,457,936 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213204,856,332 - 204,856,621 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRTAP7-1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1261,291,163 - 61,292,358 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660713,842,901 - 3,843,720 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101711618
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474519,310,508 - 19,310,744 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474519,310,493 - 19,310,744 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
LOC116894405
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12157,416,275 - 157,416,893 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:87
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000064103
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1 5 1 23 3 2 1 1 4 19 3 18 10 24 1 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000064103   ⟹   ENSRNOP00000061501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1142,226,594 - 42,227,230 (-)Ensembl
mRatBN7.2 Ensembl1128,740,390 - 28,741,003 (-)Ensembl
Rnor_6.0 Ensembl1129,640,938 - 29,641,551 (-)Ensembl
RefSeq Acc Id: NM_001145002   ⟹   NP_001138474
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81142,226,594 - 42,227,230 (-)NCBI
mRatBN7.21128,740,387 - 28,741,023 (-)NCBI
Rnor_6.01129,640,935 - 29,641,551 (-)NCBI
Rnor_5.01133,262,628 - 33,263,244 (-)NCBI
RGSC_v3.41129,298,464 - 29,299,080 (-)RGD
Celera1128,432,399 - 28,433,015 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001138474 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061501
  ENSRNOP00000061501.1
RefSeq Acc Id: NP_001138474   ⟸   NM_001145002
- UniProtKB: D4A3G7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061501   ⟸   ENSRNOT00000064103

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3G7-F1-model_v2 AlphaFold D4A3G7 1-87 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698042
Promoter ID:EPDNEW_R8566
Type:single initiation site
Name:Krtap7-1_1
Description:keratin associated protein 7-1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01129,641,571 - 29,641,631EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560879 AgrOrtholog
BioCyc Gene G2FUF-21980 BioCyc
Ensembl Genes ENSRNOG00000043017 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064103 ENTREZGENE
  ENSRNOT00000064103.4 UniProtKB/TrEMBL
InterPro Keratin-associated_7 UniProtKB/TrEMBL
KEGG Report rno:363741 UniProtKB/TrEMBL
NCBI Gene 363741 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 7-1 UniProtKB/TrEMBL
  PTHR38504 UniProtKB/TrEMBL
Pfam KRTAP7 UniProtKB/TrEMBL
PhenoGen Krtap7-1 PhenoGen
RatGTEx ENSRNOG00000043017 RatGTEx
UniProt D4A3G7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-06-22 Krtap7-1  keratin associated protein 7-1   RGD1560879  similar to ribosomal protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1560879  similar to ribosomal protein   RGD1560879_predicted  similar to ribosomal protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560879_predicted  similar to ribosomal protein (predicted)  LOC363741  similar to ribosomal protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363741  similar to ribosomal protein      Symbol and Name status set to provisional 70820 PROVISIONAL