Rps3l1 (ribosomal protein S3 like 1) - Rat Genome Database

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Pathways
Gene: Rps3l1 (ribosomal protein S3 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps3l1 (Ensembl: AABR07052430.1)
Name: ribosomal protein S3 like 1
RGD ID: 1560831
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of apoptotic signaling pathway. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in nucleus. Orthologous to human RPS3 (ribosomal protein S3); INTERACTS WITH ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S3-like; LOC499803; RGD1560831; similar to 40S ribosomal protein S3; small ribosomal subunit protein uS3-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8371,967,699 - 71,968,537 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl371,967,707 - 71,968,529 (-)EnsemblGRCr8
mRatBN7.2351,559,683 - 51,560,522 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl351,559,683 - 51,560,524 (-)EnsemblmRatBN7.2
Rnor_6.0352,997,847 - 52,998,669 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0359,616,260 - 59,617,088 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4348,862,928 - 48,863,734 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera351,135,933 - 51,136,749 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps3l1
14 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)35986366373704481Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 12 37 56 114 74 7 40 33 32 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000009988   ⟹   ENSRNOP00000009988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl371,967,707 - 71,968,529 (-)Ensembl
mRatBN7.2 Ensembl351,559,683 - 51,560,524 (-)Ensembl
Rnor_6.0 Ensembl352,997,922 - 52,998,650 (-)Ensembl
RefSeq Acc Id: XM_039106339   ⟹   XP_038962267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8371,967,699 - 71,968,537 (-)NCBI
mRatBN7.2351,559,683 - 51,560,522 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038962267 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009988
  ENSRNOP00000009988.1
  ENSRNOP00000023935.4
RefSeq Acc Id: XP_038962267   ⟸   XM_039106339
- UniProtKB: D3ZVH2 (UniProtKB/TrEMBL),   A0A8L2QCG7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000009988   ⟸   ENSRNOT00000009988
Protein Domains
KH type-2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVH2-F1-model_v2 AlphaFold D3ZVH2 1-243 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560831 AgrOrtholog
BioCyc Gene G2FUF-49536 BioCyc
Ensembl Genes ENSRNOG00000007605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000017418 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009988 ENTREZGENE
  ENSRNOT00000009988.5 UniProtKB/TrEMBL
  ENSRNOT00000023935.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.32 UniProtKB/TrEMBL
  3.30.300.20 UniProtKB/TrEMBL
InterPro KH_dom-like_a/b UniProtKB/TrEMBL
  KH_dom_type_2 UniProtKB/TrEMBL
  KH_sf_prok-type UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/TrEMBL
  Ribosomal_S3_C_sf UniProtKB/TrEMBL
  Ribosomal_S3_CS UniProtKB/TrEMBL
  Ribosomal_S3_euk/arc UniProtKB/TrEMBL
  Ribosomal_uS3 UniProtKB/TrEMBL
NCBI Gene 499803 ENTREZGENE
PANTHER 30S/40S RIBOSOMAL PROTEIN S3 UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S3 UniProtKB/TrEMBL
Pfam KH_2 UniProtKB/TrEMBL
  Ribosomal_S3_C UniProtKB/TrEMBL
PhenoGen Rps3l1 PhenoGen
PROSITE KH_TYPE_2 UniProtKB/TrEMBL
  RIBOSOMAL_S3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007605 RatGTEx
  ENSRNOG00000017418 RatGTEx
Superfamily-SCOP SSF54814 UniProtKB/TrEMBL
  SSF54821 UniProtKB/TrEMBL
UniProt A0A8L2QCG7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVH2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps3l1  ribosomal protein S3 like 1  RGD1560831  similar to 40S ribosomal protein S3  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560831  similar to 40S ribosomal protein S3   RGD1560831_predicted  similar to 40S ribosomal protein S3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560831_predicted  similar to 40S ribosomal protein S3 (predicted)  LOC499803  similar to 40S ribosomal protein S3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499803  similar to 40S ribosomal protein S3      Symbol and Name status set to provisional 70820 PROVISIONAL