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Gene: Tnfrsf13c (TNF receptor superfamily member 13C) Rattus norvegicus

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Symbol:

Tnfrsf13c

Name:

TNF receptor superfamily member 13C

RGD ID:

1560810

Description:

Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of lymphocyte activation. Predicted to act upstream of or within B cell homeostasis; positive regulation of germinal center formation; and positive regulation of type II interferon production. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency 4. Orthologous to human TNFRSF13C (TNF receptor superfamily member 13C); PARTICIPATES IN cytokine mediated signaling pathway; primary immunodeficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC500910; RGD1560810; similar to tumor necrosis factor receptor superfamily, member 13c; tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13c

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	115,616,139 - 115,618,647 (-)	NCBI		GRCr8
mRatBN7.2	7	113,736,046 - 113,738,523 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	113,736,055 - 113,738,517 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	123,453,799 - 123,456,289 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	123,453,788 - 123,456,268 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	123,438,591 - 123,439,975 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,596,571 - 120,597,836 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	110,051,209 - 110,053,699 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	COVID-19		ISO	TNFRSF13C (Homo sapiens)	9068941	mRNA:decreased expression:bronchoalveolar lavage (human)	RGD	PMID:32407669 and REF_RGD_ID:30296672
Tnfrsf13c	Rat	Mycoplasma pneumoniae pneumonia	severity	ISO	TNFRSF13C (Homo sapiens)	9068941		RGD	PMID:28302172 and REF_RGD_ID:32716376

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	adenylosuccinase lyase deficiency		ISO	TNFRSF13C (Homo sapiens)	8554872	ClinVar Annotator: match by term: Adenylosuccinate lyase deficiency	ClinVar	PMID:28492532
Tnfrsf13c	Rat	common variable immunodeficiency		ISO	TNFRSF13C (Homo sapiens)	8554872	ClinVar Annotator: match by term: Common Variable Immune Deficiency and Recessive	ClinVar	PMID:28492532
Tnfrsf13c	Rat	common variable immunodeficiency 2		ISO	TNFRSF13C (Homo sapiens)	8554872	ClinVar Annotator: match by term: Immunodeficiency more ...	ClinVar	PMID:25741868 and PMID:28492532
Tnfrsf13c	Rat	common variable immunodeficiency 4		ISO	TNFRSF13C (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:17576681 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	Brain Injuries		ISO	TNFRSF13C (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:23159883
Tnfrsf13c	Rat	common variable immunodeficiency		ISO	TNFRSF13C (Homo sapiens)	11554173	CTD Direct Evidence: marker/mechanism	CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	common variable immunodeficiency 4		ISO	TNFRSF13C (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	1,2-dimethylhydrazine	multiple interactions	EXP		6480464	[APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of TNFRSF13C mRNA	CTD	PMID:27840820
Tnfrsf13c	Rat	1,2-dimethylhydrazine	increases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of TNFRSF13C mRNA	CTD	PMID:22206623
Tnfrsf13c	Rat	17beta-estradiol	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Estradiol results in decreased expression of TNFRSF13C mRNA	CTD	PMID:19484750 and PMID:39298647
Tnfrsf13c	Rat	17beta-estradiol	multiple interactions	EXP		6480464	[bisphenol A co-treated with Estradiol] results in increased expression of TNFRSF13C mRNA	CTD	PMID:26496021
Tnfrsf13c	Rat	3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	tetrabromobisphenol A results in decreased expression of TNFRSF13C mRNA	CTD	PMID:25172293
Tnfrsf13c	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	bisphenol S results in decreased expression of TNFRSF13C mRNA	CTD	PMID:39298647
Tnfrsf13c	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Tnfrsf13c (Mus musculus)	6480464	bisphenol S affects the methylation of TNFRSF13C gene	CTD	PMID:31683443
Tnfrsf13c	Rat	alpha-Zearalanol	increases expression	EXP		6480464	Zeranol results in increased expression of TNFRSF13C mRNA	CTD	PMID:35163327
Tnfrsf13c	Rat	aristolochic acid A	increases expression	ISO	TNFRSF13C (Homo sapiens)	6480464	aristolochic acid I results in increased expression of TNFRSF13C mRNA	CTD	PMID:33212167
Tnfrsf13c	Rat	arsane	affects expression	ISO	TNFRSF13C (Homo sapiens)	6480464	Arsenic affects the expression of TNFRSF13C protein	CTD	PMID:24675094
Tnfrsf13c	Rat	arsenic atom	affects expression	ISO	TNFRSF13C (Homo sapiens)	6480464	Arsenic affects the expression of TNFRSF13C protein	CTD	PMID:24675094
Tnfrsf13c	Rat	benzalkonium chloride	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of TNFRSF13C mRNA	CTD	PMID:30171875
Tnfrsf13c	Rat	benzo[a]pyrene	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Benzo(a)pyrene results in decreased expression of TNFRSF13C mRNA	CTD	PMID:21569818
Tnfrsf13c	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Diethylhexyl Phthalate results in decreased expression of TNFRSF13C mRNA	CTD	PMID:34319233
Tnfrsf13c	Rat	bisphenol A	multiple interactions	EXP		6480464	[bisphenol A co-treated with Estradiol] results in increased expression of TNFRSF13C mRNA	CTD	PMID:26496021
Tnfrsf13c	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of TNFRSF13C mRNA	CTD	PMID:25181051
Tnfrsf13c	Rat	buta-1,3-diene	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	1 and 3-butadiene results in decreased expression of TNFRSF13C mRNA	CTD	PMID:29038090
Tnfrsf13c	Rat	carbon nanotube	affects expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Nanotubes and Carbon affects the expression of TNFRSF13C mRNA	CTD	PMID:25554681
Tnfrsf13c	Rat	carbon nanotube	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Nanotubes and Carbon analog results in decreased expression of TNFRSF13C mRNA	CTD	PMID:25554681
Tnfrsf13c	Rat	chloroprene	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Chloroprene results in decreased expression of TNFRSF13C mRNA	CTD	PMID:23125180
Tnfrsf13c	Rat	chlorpyrifos	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of TNFRSF13C mRNA	CTD	PMID:32715474
Tnfrsf13c	Rat	crocidolite asbestos	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	Asbestos and Crocidolite results in decreased expression of TNFRSF13C mRNA	CTD	PMID:29279043
Tnfrsf13c	Rat	dimethylarsinic acid	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TNFRSF13C mRNA	CTD	PMID:34876320
Tnfrsf13c	Rat	dioxygen	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TNFRSF13C mRNA	CTD	PMID:30529165
Tnfrsf13c	Rat	indole-3-methanol	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF13C mRNA	CTD	PMID:22129741
Tnfrsf13c	Rat	methylarsonic acid	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TNFRSF13C mRNA	CTD	PMID:34876320
Tnfrsf13c	Rat	N-acetyl-L-cysteine	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF13C mRNA	CTD	PMID:22129741
Tnfrsf13c	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF13C mRNA	CTD	PMID:22129741
Tnfrsf13c	Rat	nitrates	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[Particulate Matter results in increased abundance of Nitrates] which results in increased expression of TNFRSF13C mRNA	CTD	PMID:35964746
Tnfrsf13c	Rat	ozone	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TNFRSF13C mRNA	CTD	PMID:34911549
Tnfrsf13c	Rat	silicon dioxide	increases expression	EXP		6480464	Silicon Dioxide results in increased expression of TNFRSF13C mRNA	CTD	PMID:32721576
Tnfrsf13c	Rat	sodium arsenate	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TNFRSF13C mRNA	CTD	PMID:34876320
Tnfrsf13c	Rat	sodium arsenite	increases expression	ISO	TNFRSF13C (Homo sapiens)	6480464	sodium arsenite results in increased expression of TNFRSF13C mRNA	CTD	PMID:34032870
Tnfrsf13c	Rat	sodium arsenite	multiple interactions	ISO	Tnfrsf13c (Mus musculus)	6480464	[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TNFRSF13C mRNA	CTD	PMID:34876320
Tnfrsf13c	Rat	tetraphene	increases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	benz(a)anthracene results in increased expression of TNFRSF13C mRNA	CTD	PMID:26377693
Tnfrsf13c	Rat	titanium dioxide	increases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	titanium dioxide results in increased expression of TNFRSF13C mRNA	CTD	PMID:23557971
Tnfrsf13c	Rat	titanium dioxide	decreases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	titanium dioxide results in decreased expression of TNFRSF13C mRNA	CTD	PMID:27760801
Tnfrsf13c	Rat	titanium dioxide	decreases methylation	ISO	Tnfrsf13c (Mus musculus)	6480464	titanium dioxide results in decreased methylation of TNFRSF13C gene	CTD	PMID:35295148
Tnfrsf13c	Rat	triptonide	increases expression	ISO	Tnfrsf13c (Mus musculus)	6480464	triptonide results in increased expression of TNFRSF13C mRNA	CTD	PMID:33045310

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	B cell costimulation	involved_in	IBA	MGI:1919299 and PANTHER:PTN001073134	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tnfrsf13c	Rat	B cell costimulation	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	PMID:15240667	RGD	PMID:15240667
Tnfrsf13c	Rat	B cell homeostasis	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:14557413	RGD	PMID:14557413
Tnfrsf13c	Rat	B cell proliferation	acts_upstream_of	ISO	Tnfrsf13c (Mus musculus)	1624291	PMID:15240667	RGD	PMID:15240667
Tnfrsf13c	Rat	germinal center formation	acts_upstream_of	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:14557413	RGD	PMID:14557413
Tnfrsf13c	Rat	positive regulation of B cell proliferation	involved_in	IBA	MGI:1919299 and PANTHER:PTN001073134	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tnfrsf13c	Rat	positive regulation of B cell proliferation	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	PMID:15240667	RGD	PMID:15240667
Tnfrsf13c	Rat	positive regulation of germinal center formation	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:14557413	RGD	PMID:14557413
Tnfrsf13c	Rat	positive regulation of T cell proliferation	involved_in	IBA	MGI:1919299 and PANTHER:PTN001073134	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tnfrsf13c	Rat	positive regulation of T cell proliferation	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:15240667 and PMID:15368291	RGD	PMID:15240667 and PMID:15368291
Tnfrsf13c	Rat	positive regulation of type II interferon production	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:15368291	RGD	PMID:15368291
Tnfrsf13c	Rat	regulation of immune response	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:14557413 and PMID:15368291	RGD	PMID:14557413 and PMID:15368291
Tnfrsf13c	Rat	T cell costimulation	involved_in	IBA	MGI:1919299 and PANTHER:PTN001073134	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tnfrsf13c	Rat	T cell costimulation	acts_upstream_of_or_within	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:15240667 and PMID:15368291	RGD	PMID:15240667 and PMID:15368291
Tnfrsf13c	Rat	T cell proliferation	acts_upstream_of	ISO	Tnfrsf13c (Mus musculus)	1624291	MGI:2389403 PMID:15240667 and PMID:15368291	RGD	PMID:15240667 and PMID:15368291
Tnfrsf13c	Rat	tumor necrosis factor-mediated signaling pathway	involved_in	IEA	InterPro:IPR022338 and InterPro:IPR043521	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	external side of plasma membrane	is_active_in	IBA	MGI:1919299 and PANTHER:PTN001073134	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Tnfrsf13c	Rat	external side of plasma membrane	located_in	ISO	Tnfrsf13c (Mus musculus)	1624291	PMID:15240667 and PMID:15368291	RGD	PMID:15240667 and PMID:15368291
Tnfrsf13c	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	signaling receptor activity	enables	IEA	InterPro:IPR022338 and InterPro:IPR043521	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tnfrsf13c	Rat	cytokine mediated signaling pathway		IEA		6907045		KEGG	rno:04060
Tnfrsf13c	Rat	primary immunodeficiency pathway		IEA		6907045		KEGG	rno:05340

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:14557413	PMID:15240667	PMID:15368291	PMID:22124120	PMID:22391142

Tnfrsf13c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	115,616,139 - 115,618,647 (-)	NCBI		GRCr8
mRatBN7.2	7	113,736,046 - 113,738,523 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	113,736,055 - 113,738,517 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	7	123,453,799 - 123,456,289 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	123,453,788 - 123,456,268 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	123,438,591 - 123,439,975 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,596,571 - 120,597,836 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	110,051,209 - 110,053,699 (-)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

TNFRSF13C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	41,922,032 - 41,926,806 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	41,922,032 - 41,926,806 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	42,318,036 - 42,322,810 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	40,650,982 - 40,652,728 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	40,645,535 - 40,647,282	NCBI
Celera	22	26,127,271 - 26,129,056 (-)	NCBI		Celera
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	25,286,634 - 25,288,419 (-)	NCBI		HuRef
CHM1_1	22	42,281,235 - 42,283,020 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	42,400,895 - 42,405,666 (-)	NCBI		T2T-CHM13v2.0

Tnfrsf13c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	82,105,943 - 82,108,581 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	82,105,944 - 82,108,570 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	82,221,742 - 82,224,380 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	82,221,743 - 82,224,369 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	82,052,174 - 82,054,766 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	82,048,999 - 82,051,591 (-)	NCBI		MGSCv36	mm8
Celera	15	84,345,398 - 84,346,929 (-)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	38.56	NCBI

Tnfrsf13c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955413	27,341,977 - 27,344,009 (-)	NCBI	ChiLan1.0	ChiLan1.0

TNFRSF13C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	51,751,774 - 51,758,115 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	54,449,100 - 54,457,327 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	22,816,504 - 22,819,584 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

TNFRSF13C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	23,430,960 - 23,434,972 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	23,433,052 - 23,438,946 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	23,365,041 - 23,369,055 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	24,175,948 - 24,179,962 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	24,178,192 - 24,179,471 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	23,892,942 - 23,896,956 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	24,214,176 - 24,218,207 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	24,388,325 - 24,392,339 (+)	NCBI		UU_Cfam_GSD_1.0

Tnfrsf13c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	7,088,464 - 7,089,921 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936492	98,878 - 101,920 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNFRSF13C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	6,699,878 - 6,703,656 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	6,699,812 - 6,703,403 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TNFRSF13C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	24,457,381 - 24,459,438 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	100,952,971 - 100,954,833 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tnfrsf13c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	6,797,983 - 6,799,097 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	6,797,453 - 6,799,437 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tnfrsf13c
16 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	177
Count of miRNA genes:	95
Interacting mature miRNAs:	102
Transcripts:	ENSRNOT00000010086, ENSRNOT00000056037
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	111182207	135012528	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	102297359	133492884	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	94811326	116294265	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	91412594	129807172	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	103146217	116738842	Rat
1357339	Stl14	Serum triglyceride level QTL 14	3.45	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	112729683	133492707	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
631663	Bw6	Body weight QTL 6	3.4		body mass (VT:0001259)	body weight (CMO:0000012)	7	111075573	134976056	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	94811085	116738842	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	112308254	133492884	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	33	58	79	78	47	25	47	6	182	81	38	37	54	31


RefSeq Transcripts	NM_001431971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001077542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_576316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC113253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000056037 ⟹ ENSRNOP00000052889

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	113,736,055 - 113,738,517 (-)	Ensembl
Rnor_6.0 Ensembl	7	123,453,788 - 123,456,268 (-)	Ensembl

RefSeq Acc Id:

XM_576316 ⟹ XP_576316

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	115,616,139 - 115,618,647 (-)	NCBI
mRatBN7.2	7	113,736,046 - 113,738,523 (-)	NCBI
Rnor_6.0	7	123,453,799 - 123,456,289 (-)	NCBI
Rnor_5.0	7	123,438,591 - 123,439,975 (-)	NCBI
RGSC_v3.4	7	120,596,571 - 120,597,836 (-)	RGD

Sequence:

show sequence

TTTCATTCTAGACCAGAGAGACCCAGAGCCCAGACTGTCCCAGCTGCATGCGGCGGCGACATGGGCGTCAGGAGGCTCCGGGTCAGAAGCCGGAGGAGCCGGGACAGCCCGGTGTCCACCCAGTGCAA
TCAGACTGAGTGCTTCGACCCTCTGGTGCGAAACTGCGTGTCCTGTGAGCTCTTCTACACGCCGGAAACTAGACATGCAAGCAGCCTGGAGCCCGGGACAGCTCTGCAGCCTCAGGAGGGCTCCGGGC
TGAGACCCGATGTGGCGCTGCTCTTCGGTGCCCCCGCGCTCCTGGGACTGGTGCTGGCACTGACCCTGGTGGGTCTGGTGAGTCTGGTGGGCTGGAGGTGGCGGCAACAGCGCAGGACAGCCTCCTTG
GACACTTCCGAAGGAGTCCAGCAAGAGTCCCTGGAAAATGTCTTTGTACCCCCCTCGGAAACCCTTCATGCCTCAGCTCCTAACTGGCCTCCATTCAAAGAAGATGCAGACAACATCCTGTCGTGCCA
CAGCATCCCAGTGCCAGCCACAGAACTGGGCTCCACTGAGCTGGTGACCACCAAGACAGCTGGCCCTGAGCAGTAGCAGCAGCGGAGAAGCCCAGGGAGCCCTACTGGGCTCATGGACTTTCACCCAA
CAGCTTGGAAAAGAAAAGAATTCAACCCTTCAGTGATGGAGACCTTTACCTGGGGCTGAACCCAGCAGAACCAGACACTACAGGCCACAGGCTCCCACCCGCAGGAGATTGTTTCCGTGTTAGCTTTG
GGCTTGAGAACATTCCATTTTTGAGGTCGTTTTTTTAAGTTTGTGTGCCTTCCGATGGTTGGGTAGGCTTAAGTGCTGAATATTAATCTCTTTAATGAGTCAGAGACTGGAAACGAAAATCTCTTTCT
AAAAATTTTGGATGACGGACTGGAGACGTGGCTCAGCAGTTAAGTATATGTGCCGTCCTAGAAGAGAACTCCAGTTGTTCAGTTCCCCAGCACTCATATCTGGCCGCTGAAAACCACCCGTAACTCAG
CCCCAGGAATATCCTTGTCTGTAAAGGAACCAGCTCTCACAGCTCCAGTTTGTACACACACACACACACACACACACACACACACACACACACACACACACACACACACTTTTACAAGTTATCAAATA
TAAGATGGGCATGAATGGTGGCACAGGCCTTTAATCCCAACACTGGGAGGCAGAGGCAGGCAGATCTCTGAGTTGGAGGCCATCCTGGTCTACATAGCGAGTTCCAGGCTAACCAGCGCTATATGGTG
AGACCAGGTCTCCAAATGATACCAAAACTGAAATCTTTTTAAATTCTGATTTTTTTCCCTTTATTATTATTATTTTTAAATTCATCTCACGGTGTTTAGAAGTGGTATACTTGGATGGTGACTAAGAT
GAGGTCAAGCCATCAGGACCAAGCCCCCAAGATACAAAGAGAGACAAGAGACAATGAACACGCCCCCTCCCGCCGCGTGATGGGCTGTGCCAACTCTGGACTTCACCAGACAGAGGGCAATCATCAGA
TGCCGGCCCTCGAACCTGAAGAGCTGTAAGCTAAAATCAATCTCATTCCTTCATAAAGTTACTCAGCCTTGGGCGTTTCGTTACAGTAATATAAAACTGACTAACACAGGCGCTATGAGTAAGAGGTT
TTTTCCTTTCAGCTGGGGGCGGGGAAGGTACTGTTAAACCAAAATTAATCTAAATAAAGAAAGGCTGTGGGGAAGATGCATAATCTGTA

hide sequence


Protein RefSeqs	NP_001418900	(Get FASTA)	NCBI Sequence Viewer
	XP_576316	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000052889
	ENSRNOP00000052889.3

RefSeq Acc Id:	XP_576316 ⟸ XM_576316
- Sequence:	show sequence MGVRRLRVRSRRSRDSPVSTQCNQTECFDPLVRNCVSCELFYTPETRHASSLEPGTALQPQEGSGLRPDVALLFGAPALLGLVLALTLVGLVSLVGWRWRQQRRTASLDTSEGVQQESLENVFVPPSE TLHASAPNWPPFKEDADNILSCHSIPVPATELGSTELVTTKTAGPEQ hide sequence

Ensembl Acc Id:

ENSRNOP00000052889 ⟸ ENSRNOT00000056037

Protein Domains

Tumour necrosis factor receptor 13C TALL-1 binding

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A281-F1-model_v2	AlphaFold	D4A281	1-175	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13695533

Promoter ID:

EPDNEW_R6054

Type:

multiple initiation site

Name:

Tnfrsf13c_1

Description:

TNF receptor superfamily member 13C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	123,456,258 - 123,456,318	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-32637	BioCyc
Ensembl Genes	ENSRNOG00000007664	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000056037	ENTREZGENE
	ENSRNOT00000056037.4	UniProtKB/TrEMBL
InterPro	TNFR_13C	UniProtKB/TrEMBL
	TNFR_13C/17	UniProtKB/TrEMBL
	TNFR_13C_TALL-1-bd	UniProtKB/TrEMBL
KEGG Report	rno:500910	UniProtKB/TrEMBL
NCBI Gene	500910	ENTREZGENE
PANTHER	PTHR20437	UniProtKB/TrEMBL
	PTHR20437:SF2	UniProtKB/TrEMBL
Pfam	BaffR-Tall_bind	UniProtKB/TrEMBL
PhenoGen	Tnfrsf13c	PhenoGen
PRINTS	TNFACTORR13C	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007664	RatGTEx
Superfamily-SCOP	TNF receptor-like	UniProtKB/TrEMBL
UniProt	D4A281	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-05	Tnfrsf13c	TNF receptor superfamily member 13C	Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-28	Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	RGD1560810_predicted	similar to tumor necrosis factor receptor superfamily, member 13c (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1560810_predicted	similar to tumor necrosis factor receptor superfamily, member 13c (predicted)	LOC500910	similar to tumor necrosis factor receptor superfamily, member 13c	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC500910	similar to tumor necrosis factor receptor superfamily, member 13c			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Annotations - KEGG (archival)