Rad51b (RAD51 paralog B) - Rat Genome Database

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Pathways
Gene: Rad51b (RAD51 paralog B) Rattus norvegicus
Analyze
Symbol: Rad51b
Name: RAD51 paralog B
RGD ID: 1560681
Description: Predicted to enable ATP-dependent activity, acting on DNA; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and positive regulation of G2/M transition of mitotic cell cycle. Predicted to act upstream of or within blastocyst growth; positive regulation of cell population proliferation; and somite development. Predicted to be located in nucleus. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Predicted to be active in replication fork. Orthologous to human RAD51B (RAD51 paralog B); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 1-naphthyl isothiocyanate; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA repair protein RAD51 homolog 2; LOC500679; RAD51 homolog B; RAD51 homolog B (S. cerevisiae); RAD51-like 1; RAD51-like 1 (S. cerevisiae); Rad51l1; RGD1560681; similar to RAD51-like 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,829,390 - 104,373,923 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6103,829,554 - 104,374,509 (+)EnsemblGRCr8
mRatBN7.2698,096,525 - 98,640,988 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx698,525,988 - 99,062,959 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,825,134 - 99,362,047 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,211,622 - 98,750,469 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,473,978 - 103,018,185 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)Ensemblrn6Rnor6.0
Rnor_5.06115,160,014 - 115,699,112 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46102,069,799 - 102,134,176 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera696,481,576 - 97,009,269 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
fenofibrate  (ISO)
formaldehyde  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
glucose  (ISO)
glycidol  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
myristicin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
Ptaquiloside  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of homologous recombination in eukaryotes. Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10567591   PMID:11751635   PMID:12441335   PMID:20207730   PMID:23108668   PMID:23149936  


Genomics

Comparative Map Data
Rad51b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,829,390 - 104,373,923 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6103,829,554 - 104,374,509 (+)EnsemblGRCr8
mRatBN7.2698,096,525 - 98,640,988 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx698,525,988 - 99,062,959 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,825,134 - 99,362,047 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0698,211,622 - 98,750,469 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,473,978 - 103,018,185 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)Ensemblrn6Rnor6.0
Rnor_5.06115,160,014 - 115,699,112 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46102,069,799 - 102,134,176 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera696,481,576 - 97,009,269 (+)NCBICelera
Cytogenetic Map6q24NCBI
RAD51B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,819,779 - 68,683,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,819,779 - 68,730,218 (+)Ensemblhg38GRCh38
GRCh371468,286,496 - 69,149,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,356,262 - 68,132,367 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341467,356,261 - 68,014,562NCBI
Celera1448,345,516 - 49,121,494 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,455,813 - 49,231,230 (+)NCBIHuRef
CHM1_11468,225,211 - 69,001,135 (+)NCBICHM1_1
T2T-CHM13v2.01462,026,883 - 62,889,971 (+)NCBIT2T-CHM13v2.0
Rad51b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,344,032 - 79,895,034 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,344,056 - 79,861,464 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381279,297,282 - 79,848,260 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,297,282 - 79,814,690 (+)Ensemblmm10GRCm38
MGSCv371280,398,269 - 80,915,677 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361280,216,122 - 80,733,530 (+)NCBIMGSCv36mm8
Celera1280,761,261 - 81,278,996 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Rad51b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,137,192 - 2,381,450 (-)Ensembl
ChiLan1.0NW_0049554661,686,472 - 2,388,146 (-)NCBIChiLan1.0ChiLan1.0
RAD51B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,926,972 - 69,844,939 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11468,145,747 - 69,061,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,399,345 - 49,314,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11467,277,400 - 68,189,780 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1467,281,148 - 68,110,693 (+)EnsemblpanPan2panpan1.1
RAD51B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,779,435 - 42,357,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,778,714 - 42,357,298 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha841,469,217 - 42,151,951 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0842,009,371 - 42,691,934 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl842,009,155 - 42,586,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,624,025 - 42,306,963 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,699,024 - 42,381,539 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0842,056,861 - 42,740,806 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rad51b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864062,431,048 - 62,999,072 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649511,195,767 - 11,467,458 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649511,185,560 - 11,762,254 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD51B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl791,592,424 - 92,345,294 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1791,592,413 - 92,301,383 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2797,899,832 - 98,613,557 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD51B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12445,056,485 - 45,704,394 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605333,285,609 - 34,057,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad51b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473432,560,579 - 33,173,357 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rad51b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1793,397,318 - 93,908,084 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rad51b
3492 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)699437079125323237Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)699708426112483760Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat

Markers in Region
D6Wox4  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr86104,066,718 - 104,066,876 (+)Marker Load Pipeline
mRatBN7.2698,333,755 - 98,333,915 (+)MAPPERmRatBN7.2
Rnor_6.06102,717,943 - 102,718,100NCBIRnor6.0
Rnor_5.06115,398,337 - 115,398,494UniSTSRnor5.0
RGSC_v3.46102,452,429 - 102,452,587RGDRGSC3.4
RGSC_v3.46102,452,430 - 102,452,587UniSTSRGSC3.4
Celera696,711,893 - 96,712,050UniSTS
RGSC_v3.16102,455,886 - 102,456,043RGD
RH 3.4 Map6692.5RGD
RH 3.4 Map6692.5UniSTS
RH 2.0 Map6901.7RGD
Cytogenetic Map6q24UniSTS
D6Got121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,551,637 - 98,551,864 (+)MAPPERmRatBN7.2
Rnor_6.06102,931,707 - 102,931,933NCBIRnor6.0
Rnor_5.06115,611,771 - 115,611,997UniSTSRnor5.0
RGSC_v3.46102,675,640 - 102,675,867RGDRGSC3.4
RGSC_v3.46102,675,641 - 102,675,867UniSTSRGSC3.4
Celera696,920,677 - 96,920,903UniSTS
RGSC_v3.16102,679,097 - 102,679,323RGD
RH 3.4 Map6697.2UniSTS
RH 3.4 Map6697.2RGD
Cytogenetic Map6q24UniSTS
AI553500  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,695 - 98,640,830 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,893 - 103,018,027NCBIRnor6.0
Rnor_5.06115,698,820 - 115,698,954UniSTSRnor5.0
Celera697,008,977 - 97,009,111UniSTS
Cytogenetic Map6q24UniSTS
AI326150  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,280,851 - 98,280,977 (+)MAPPERmRatBN7.2
Rnor_6.06102,664,014 - 102,664,139NCBIRnor6.0
Rnor_5.06115,345,540 - 115,345,665UniSTSRnor5.0
RGSC_v3.46102,399,647 - 102,399,772UniSTSRGSC3.4
Celera696,659,301 - 96,659,426UniSTS
Cytogenetic Map6q24UniSTS
RH139568  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,666 - 98,640,846 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,864 - 103,018,043NCBIRnor6.0
Rnor_5.06115,698,791 - 115,698,970UniSTSRnor5.0
Celera697,008,948 - 97,009,127UniSTS
Cytogenetic Map6q24UniSTS
AW532941  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,166,307 - 98,166,491 (+)MAPPERmRatBN7.2
Rnor_6.06102,547,417 - 102,547,600NCBIRnor6.0
Rnor_5.06115,228,274 - 115,228,457UniSTSRnor5.0
RGSC_v3.46102,139,254 - 102,139,437UniSTSRGSC3.4
Celera696,549,894 - 96,550,077UniSTS
RH 3.4 Map6691.7UniSTS
Cytogenetic Map6q24UniSTS
RH139454  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,640,635 - 98,640,755 (+)MAPPERmRatBN7.2
Rnor_6.06103,017,833 - 103,017,952NCBIRnor6.0
Rnor_5.06115,698,760 - 115,698,879UniSTSRnor5.0
Celera697,008,917 - 97,009,036UniSTS
RH 3.4 Map6692.0UniSTS
Cytogenetic Map6q24UniSTS
AU049680  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,522,003 - 98,522,231 (+)MAPPERmRatBN7.2
Rnor_6.06102,903,893 - 102,904,118NCBIRnor6.0
Rnor_5.06115,583,963 - 115,584,188UniSTSRnor5.0
RGSC_v3.46102,643,644 - 102,643,869UniSTSRGSC3.4
Celera696,893,688 - 96,893,913UniSTS
Cytogenetic Map6q24UniSTS
Fzd6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2698,100,874 - 98,100,975 (+)MAPPERmRatBN7.2
Rnor_6.06102,478,321 - 102,478,421NCBIRnor6.0
Rnor_5.06115,164,269 - 115,164,369UniSTSRnor5.0
RGSC_v3.46102,071,084 - 102,071,184UniSTSRGSC3.4
Celera696,485,919 - 96,486,019UniSTS
Cytogenetic Map6q24UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
17 12 76 191 90 89 58 102 58 6 397 220 22 169 94 123 31 19 19

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039113283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005506073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000087132   ⟹   ENSRNOP00000068685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,829,554 - 104,056,830 (+)Ensembl
mRatBN7.2 Ensembl698,099,575 - 98,323,866 (+)Ensembl
Rnor_6.0 Ensembl6102,477,036 - 102,512,505 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105193   ⟹   ENSRNOP00000084086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,829,554 - 104,374,498 (+)Ensembl
mRatBN7.2 Ensembl698,099,575 - 98,640,979 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116880   ⟹   ENSRNOP00000091401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,829,554 - 104,374,509 (+)Ensembl
mRatBN7.2 Ensembl698,098,868 - 98,640,979 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145394   ⟹   ENSRNOP00000107514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,829,554 - 104,367,925 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000147746   ⟹   ENSRNOP00000103998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,829,554 - 104,368,936 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157859   ⟹   ENSRNOP00000107982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6103,835,328 - 104,374,498 (+)Ensembl
RefSeq Acc Id: NM_001399175   ⟹   NP_001386104
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,554 - 104,373,923 (+)NCBI
mRatBN7.2698,096,571 - 98,640,988 (+)NCBI
RefSeq Acc Id: XM_017594475   ⟹   XP_017449964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,493 - 104,373,905 (+)NCBI
mRatBN7.2698,096,525 - 98,640,988 (+)NCBI
Rnor_6.06102,473,993 - 103,018,185 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594476   ⟹   XP_017449965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,391 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
Rnor_6.06102,473,993 - 103,014,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039113277   ⟹   XP_038969205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,495 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113278   ⟹   XP_038969206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,536 - 104,369,164 (+)NCBI
mRatBN7.2698,096,535 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113279   ⟹   XP_038969207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,497 - 104,373,905 (+)NCBI
mRatBN7.2698,096,526 - 98,640,988 (+)NCBI
RefSeq Acc Id: XM_039113281   ⟹   XP_038969209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,494 - 104,369,164 (+)NCBI
mRatBN7.2698,096,525 - 98,637,105 (+)NCBI
RefSeq Acc Id: XM_039113282   ⟹   XP_038969210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,492 - 104,297,936 (+)NCBI
mRatBN7.2698,096,525 - 98,564,940 (+)NCBI
RefSeq Acc Id: XM_039113283   ⟹   XP_038969211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,492 - 103,906,996 (+)NCBI
mRatBN7.2698,096,525 - 98,167,202 (+)NCBI
RefSeq Acc Id: XM_063262317   ⟹   XP_063118387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,530 - 103,906,996 (+)NCBI
RefSeq Acc Id: XR_005506073
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,495 - 104,373,905 (+)NCBI
mRatBN7.2698,096,525 - 98,640,988 (+)NCBI
RefSeq Acc Id: XR_010052147
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86103,829,390 - 104,373,905 (+)NCBI
RefSeq Acc Id: XP_017449964   ⟸   XM_017594475
- Peptide Label: isoform X4
- UniProtKB: A6HCH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449965   ⟸   XM_017594476
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068685   ⟸   ENSRNOT00000087132
RefSeq Acc Id: XP_038969205   ⟸   XM_039113277
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969209   ⟸   XM_039113281
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AFI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969210   ⟸   XM_039113282
- Peptide Label: isoform X6
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969211   ⟸   XM_039113283
- Peptide Label: isoform X7
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969207   ⟸   XM_039113279
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZYE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969206   ⟸   XM_039113278
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000084086   ⟸   ENSRNOT00000105193
Ensembl Acc Id: ENSRNOP00000091401   ⟸   ENSRNOT00000116880
RefSeq Acc Id: NP_001386104   ⟸   NM_001399175
- UniProtKB: A0A8I5ZYE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118387   ⟸   XM_063262317
- Peptide Label: isoform X7
- UniProtKB: A0A0G2JTF1 (UniProtKB/TrEMBL),   A6HCH4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107982   ⟸   ENSRNOT00000157859
Ensembl Acc Id: ENSRNOP00000103998   ⟸   ENSRNOT00000147746
Ensembl Acc Id: ENSRNOP00000107514   ⟸   ENSRNOT00000145394
Protein Domains
RecA family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JTF1-F1-model_v2 AlphaFold A0A0G2JTF1 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560681 AgrOrtholog
BioCyc Gene G2FUF-36967 BioCyc
Ensembl Genes ENSRNOG00000059245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000087132 ENTREZGENE
  ENSRNOT00000087132.3 UniProtKB/TrEMBL
  ENSRNOT00000105193 ENTREZGENE
  ENSRNOT00000105193.2 UniProtKB/TrEMBL
  ENSRNOT00000116880 ENTREZGENE
  ENSRNOT00000116880.2 UniProtKB/TrEMBL
  ENSRNOT00000145394.1 UniProtKB/TrEMBL
  ENSRNOT00000147746 ENTREZGENE
  ENSRNOT00000147746.1 UniProtKB/TrEMBL
  ENSRNOT00000157859.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb/repair_RecA-like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RAD51B UniProtKB/TrEMBL
  RecA_ATP-bd UniProtKB/TrEMBL
NCBI Gene 500679 ENTREZGENE
PANTHER DNA REPAIR PROTEIN RAD51 HOMOLOG 2 UniProtKB/TrEMBL
  PTHR46456 UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PhenoGen Rad51b PhenoGen
PIRSF Rad51 UniProtKB/TrEMBL
PROSITE RECA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059245 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JTF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFI5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LR61_RAT UniProtKB/TrEMBL
  A0ABK0LTU5_RAT UniProtKB/TrEMBL
  A0ABK0LUU4_RAT UniProtKB/TrEMBL
  A6HCH3 ENTREZGENE, UniProtKB/TrEMBL
  A6HCH4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-23 Rad51b  RAD51 paralog B  Rad51b  RAD51 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Rad51b  RAD51 homolog B (S. cerevisiae)  Rad51l1  RAD51-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Rad51l1  RAD51-like 1 (S. cerevisiae)  RGD1560681_predicted  similar to RAD51-like 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560681_predicted  similar to RAD51-like 1 (predicted)  LOC500679  similar to RAD51-like 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500679  similar to RAD51-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL