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Gene: Vnn3 (vanin 3) Rattus norvegicus

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Symbol:

Vnn3

Name:

vanin 3

RGD ID:

1560609

Description:

Predicted to enable pantetheine hydrolase activity. Predicted to be involved in pantothenate metabolic process. Predicted to be located in extracellular space. Orthologous to human VNN3P (vanin 3, pseudogene); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC498992; RGD1560609; similar to Vanin-3; vascular non-inflammatory molecule 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VNN3P (vanin 3, pseudogene)	HGNC	EggNOG, Ensembl, Inparanoid, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Vnn3 (vanin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VNN3P (vascular non-inflammatory molecule 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VNN3 (vanin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vnn3 (vanin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VNN3 (vanin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	VNN3P (vanin 3, pseudogene)	Alliance	DIOPT (HGNC)
Homo sapiens (human):	VNN3P (vanin 3, pseudogene)	Alliance	DIOPT (HGNC\|OrthoFinder\|PhylomeDB)
Mus musculus (house mouse):	Vnn3 (vanin 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Btnd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Btnd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32750	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32750	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32751	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32751	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	vanin-like	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	vanin-like	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	vnn2	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	23,390,596 - 23,402,858 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	23,390,596 - 23,402,858 (-)	Ensembl				GRCr8
mRatBN7.2	1	21,571,364 - 21,583,626 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	21,571,364 - 21,583,626 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	21,350,643 - 21,362,878 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	27,350,688 - 27,362,923 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	21,547,949 - 21,560,211 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	22,649,114 - 22,661,376 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	22,649,081 - 22,661,377 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	24,123,604 - 24,135,887 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	22,121,744 - 22,134,006 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	20,314,428 - 20,326,690 (-)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

psoriasis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

atrazine (EXP)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (EXP,ISO)

ciprofibrate (ISO)

clofibrate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

flutamide (EXP)

glyphosate (EXP)

hydrogen peroxide (ISO)

imidacloprid (EXP)

L-ascorbic acid (ISO)

manganese atom (EXP)

manganese(0) (EXP)

manganese(II) chloride (EXP)

methotrexate (ISO)

methoxychlor (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodiethylamine (ISO)

octadecanoic acid (ISO)

okadaic acid (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

rosuvastatin calcium (ISO)

silicon dioxide (ISO)

testosterone (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

thiabendazole (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

pantothenate metabolic process (IBA,IEA,ISO)

Cellular Component

extracellular space (IEA,ISO)

Molecular Function

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IEA)

pantetheine hydrolase activity (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11491533

Genomics

Comparative Map Data

Vnn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	23,390,596 - 23,402,858 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	23,390,596 - 23,402,858 (-)	Ensembl				GRCr8
mRatBN7.2	1	21,571,364 - 21,583,626 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	21,571,364 - 21,583,626 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	21,350,643 - 21,362,878 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	27,350,688 - 27,362,923 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	21,547,949 - 21,560,211 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	22,649,114 - 22,661,376 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	22,649,081 - 22,661,377 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	24,123,604 - 24,135,887 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	22,121,744 - 22,134,006 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	20,314,428 - 20,326,690 (-)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

VNN3P
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	132,722,787 - 132,734,765 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	132,722,784 - 132,736,935 (-)	Ensembl			hg38	GRCh38
GRCh38.p14 Ensembl	6	132,722,926 - 132,734,692 (-)	Ensembl			hg38	GRCh38
GRCh37	6	133,043,926 - 133,055,904 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	133,085,619 - 133,097,596 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	133,091,572 - 133,097,588	NCBI
Celera	6	133,790,754 - 133,802,735 (-)	NCBI		Celera
Cytogenetic Map	6	q23.2	NCBI
HuRef	6	130,618,895 - 130,630,877 (-)	NCBI		HuRef
CHM1_1	6	133,307,608 - 133,319,589 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	133,917,754 - 133,929,732 (-)	NCBI		T2T-CHM13v2.0

Vnn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	23,727,360 - 23,745,741 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	23,727,360 - 23,745,741 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	23,851,462 - 23,869,843 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	23,851,462 - 23,869,843 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	23,571,268 - 23,589,649 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	23,540,888 - 23,559,257 (+)	NCBI		MGSCv36	mm8
Celera	10	24,782,733 - 24,795,410 (+)	NCBI		Celera
Cytogenetic Map	10	A4	NCBI
cM Map	10	11.24	NCBI

VNN3P
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	152,706,178 - 152,718,156 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	150,613,326 - 150,625,180 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	130,499,664 - 130,511,900 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	134,607,541 - 134,619,514 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

VNN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	1	26,713,673 - 26,722,269 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	25,829,940 - 25,838,649 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0

Vnn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	120,955,485 - 120,962,032 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936560	734,701 - 741,248 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VNN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	1	30,981,596 - 30,993,259 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	34,501,330 - 34,512,997 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in Vnn3
115 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	36
Count of miRNA genes:	34
Interacting mature miRNAs:	36
Transcripts:	ENSRNOT00000021896
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	5293229	34184556	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
70179	Xhs2	X-ray hypersensitivity QTL 2	3.2		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	1	1	43965634	Rat
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	26564886	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	10379492	55379492	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	5293229	34184556	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	17315378	51816258	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	1	26564886	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	12820494	57820494	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	1	34184556	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	20656420	65656420	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	1	28483164	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	20508326	65508326	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	11684464	56684464	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	5293229	34184556	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	1	29	69	79	78	52	62	52	6	227	120	11	43	48	72	26	1	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC130057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021896 ⟹ ENSRNOP00000021897

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	23,390,596 - 23,402,858 (-)	Ensembl
mRatBN7.2 Ensembl	1	21,571,364 - 21,583,626 (-)	Ensembl
Rnor_6.0 Ensembl	1	22,649,081 - 22,661,377 (-)	Ensembl

RefSeq Acc Id:

NM_001109136 ⟹ NP_001102606

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	23,390,596 - 23,402,858 (-)	NCBI
mRatBN7.2	1	21,571,364 - 21,583,626 (-)	NCBI
Rnor_6.0	1	22,649,114 - 22,661,376 (-)	NCBI
Rnor_5.0	1	24,123,604 - 24,135,887 (-)	NCBI
RGSC_v3.4	1	22,121,744 - 22,134,006 (-)	RGD
Celera	1	20,314,428 - 20,326,690 (-)	RGD

Sequence:

show sequence

ATATATTCACAGGGCAATGAATGCAGCTGGCCGTCGTCGGGGCTTGAGTCTGAATATTTCCCCG
CTGATAGACAGTAGAAGAACCTTCTGATCTTCAGGGCTCACTATATTTTAACTATGGTTTCCTT
ATATTTTCCTCAATGTGTAGTGAGTTTTGTCCTCTTTGCCCAGGCTGTGGGTGCAATGGACACT
TTTATTGCTGCTGTATACGAGCATGCTGTTATATTGCCAAACAAAACAGAAAGTCCTGTTTCCA
ACGAAGAGGCTTTGCTCCTGATAAACAAGAACATAGACATTTTGGAGAATGCAATCAAGTTGGC
GGCCAGACAGGGCGCCCATATCATTGTGACCCCAGAAGATGGGATCTATGGCTGGATCTTCACC
AGGGAGACTATTTACCCCTACCTAGAGGATATACCAGACCCCGAAGTGAACTGGATTCCCTGTA
GAGACCCTAAGAGGTTTGGCTTCACACCAGTCCAGGAGAGACTCAGCTGCCTCGCCAAGGAGAA
CTCTATCTATATTGTGGCAAATATTGGGGACAAGAAGCCATGTAATACTACTGATCCTCAGTGT
CCCCGGGATGGCCGTTACCAATATAATACCAACGTGGTCTTCGATTCTGAGGGTAGGCTAACAG
CCCGCTACCATAAGTACAATCTTTTTGAACCAGAGATTCAGTTTGACTTCCCCAAGGATTCAGA
GCTGGTGACCTTTGACACTCCCTTTGGGAAGTTTGGTGTCTTCACTTGCTTTGACATTTTTTCT
TATGACCCAGCCGTGATGGTTGTGAAGGACTCCCGGGTTGACAGTGTTCTCCTGCCCACGGCGT
GGTACAACACGCTGCCCCTGCTTTCAGCAGTTCCATTCCATTCAGCGTGGGCCAGAGCCATGGG
GGTCAACGTGCTTGCTGCAAACACCCACAACACCAGAATGCACATGACAGGGAGTGGAATCTAC
AGCCCCGACGCCGTCAGAGTGTACTACTACGACATGGAGACAGAGAACGGCCAGCTGCTGCTGT
CTGAGTTGAGGTCGCGGCCCCGCCAGCATGGCTTCCCTGCAGAAGTTGACTGGAGCGCTTATGC
CAGGACCGTGAAGCCGTTCTCATCGGAGCAGGCAGACTTCCAGGGGACAATTTATTTTGATGAA
TTCAGCTTCACCAAGCTTATGGGAAGTGCTGGCAATTACACAGTTTGCCAAAAAGACCTGTGCT
GTCACCTGACTTACAAGATGTCTGAGAGCCGAATGGATGAGGCATATGTCCTGGGTGCCTTTGA
CGGACTCCATACAGTGGAAGGCCAGTATTACTTACAGATATGCACATTGCTGAAGTGTCAAACC
ACCAACTTGAGAACTTGTGGGGAACCCGTGGGGTCAGCGTTTACAAAGTTTGAAGAATTCTCTC
TCAGTGGCACCTTTGGGACGAAATATGTTTTCCCACAGATCGTCCTAAGCGGGAGTCAACTTGC
CCTGGAAAGATATTATGAAGTCTCAAGAGATGGTCGCCTGAGGAGCCGAGGTGGAGCCCCTTTG
CCTGTCTTAGTGATGGCACTGTATGGAAGGGTGTTTGAGAGGGACCCTCCGCGCTTAGGACAGG
GACCTGGGAAGGTGCAATGATCCCCTTCATCGGGGGCTGTCAGGATTAGCCTGGCAAAACGCTG
GGCTGTCAATGAGAGAGAACAGGGATCTGCATAAGAAGATACAACGTAAGCTGCTGAAATGACA
AATCACATGAAACAAGCAATAAAAT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102606	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL87745	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021897
	ENSRNOP00000021897.5

RefSeq Acc Id:	NP_001102606 ⟸ NM_001109136
- Peptide Label:	precursor
- UniProtKB:	D4A183 (UniProtKB/TrEMBL), A6JUN4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVSLYFPQCVVSFVLFAQAVGAMDTFIAAVYEHAVILPNKTESPVSNEEALLLINKNIDILENA IKLAARQGAHIIVTPEDGIYGWIFTRETIYPYLEDIPDPEVNWIPCRDPKRFGFTPVQERLSCL AKENSIYIVANIGDKKPCNTTDPQCPRDGRYQYNTNVVFDSEGRLTARYHKYNLFEPEIQFDFP KDSELVTFDTPFGKFGVFTCFDIFSYDPAVMVVKDSRVDSVLLPTAWYNTLPLLSAVPFHSAWA RAMGVNVLAANTHNTRMHMTGSGIYSPDAVRVYYYDMETENGQLLLSELRSRPRQHGFPAEVDW SAYARTVKPFSSEQADFQGTIYFDEFSFTKLMGSAGNYTVCQKDLCCHLTYKMSESRMDEAYVL GAFDGLHTVEGQYYLQICTLLKCQTTNLRTCGEPVGSAFTKFEEFSLSGTFGTKYVFPQIVLSG SQLALERYYEVSRDGRLRSRGGAPLPVLVMALYGRVFERDPPRLGQGPGKVQ hide sequence

Ensembl Acc Id:

ENSRNOP00000021897 ⟸ ENSRNOT00000021896

Protein Domains

CN hydrolase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A183-F1-model_v2	AlphaFold	D4A183	1-500	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689532

Promoter ID:

EPDNEW_R56

Type:

initiation region

Name:

Vnn3_1

Description:

vanin 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	22,661,331 - 22,661,391	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560609	AgrOrtholog
BioCyc Gene	G2FUF-62077	BioCyc
Ensembl Genes	ENSRNOG00000039865	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021896	ENTREZGENE
	ENSRNOT00000021896.8	UniProtKB/TrEMBL
Gene3D-CATH	3.60.110.10	UniProtKB/TrEMBL
InterPro	Biotinidase/VNN	UniProtKB/TrEMBL
	Biotinidase_euk	UniProtKB/TrEMBL
	C-N_Hydrolase_sf	UniProtKB/TrEMBL
	Ntlse/CNhydtse	UniProtKB/TrEMBL
	Vanin_C	UniProtKB/TrEMBL
KEGG Report	rno:498992	UniProtKB/TrEMBL
NCBI Gene	498992	ENTREZGENE
PANTHER	PTHR10609	UniProtKB/TrEMBL
	VASCULAR NON-INFLAMMATORY MOLECULE 3	UniProtKB/TrEMBL
Pfam	CN_hydrolase	UniProtKB/TrEMBL
	Vanin_C	UniProtKB/TrEMBL
PhenoGen	Vnn3	PhenoGen
PIRSF	Biotinidase	UniProtKB/TrEMBL
PROSITE	CN_HYDROLASE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000039865	RatGTEx
Superfamily-SCOP	Ntlse/CNhydtse	UniProtKB/TrEMBL
UniProt	A6JUN4	ENTREZGENE, UniProtKB/TrEMBL
	D4A183	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-28	Vnn3	vanin 3	RGD1560609_predicted	similar to Vanin-3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1560609_predicted	similar to Vanin-3 (predicted)	LOC498992	similar to Vanin-3	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498992	similar to Vanin-3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD