P2ry10b (P2Y receptor family member 10B) - Rat Genome Database

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Gene: P2ry10b (P2Y receptor family member 10B) Rattus norvegicus
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Symbol: P2ry10b
Name: P2Y receptor family member 10B
RGD ID: 1560455
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human P2RY10BP (P2Y receptor family member 10B, pseudogene); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC302377; LOC302377; purinergic receptor P2Y, G-protein coupled 10B; Putative P2Y purinoceptor 10-like; RGD1560455; similar to RIKEN cDNA A630033H20 gene; uncharacterized protein LOC302377
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X76,328,434 - 76,353,571 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX76,328,407 - 76,353,564 (+)EnsemblGRCr8
mRatBN7.2X72,255,526 - 72,281,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX72,238,713 - 72,281,012 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX73,752,571 - 73,777,068 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X77,272,415 - 77,296,891 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X74,832,779 - 74,857,303 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X78,258,495 - 78,284,180 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX78,259,409 - 78,284,180 (+)Ensemblrn6Rnor6.0
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X95,406,770 - 95,431,252 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX73,550,447 - 73,574,964 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
P2ry10b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X76,328,434 - 76,353,571 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX76,328,407 - 76,353,564 (+)EnsemblGRCr8
mRatBN7.2X72,255,526 - 72,281,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX72,238,713 - 72,281,012 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX73,752,571 - 73,777,068 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X77,272,415 - 77,296,891 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X74,832,779 - 74,857,303 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X78,258,495 - 78,284,180 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX78,259,409 - 78,284,180 (+)Ensemblrn6Rnor6.0
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X95,406,770 - 95,431,252 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX73,550,447 - 73,574,964 (+)NCBICelera
Cytogenetic MapXq22NCBI
P2RY10BP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X79,084,928 - 79,085,987 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX79,084,936 - 79,085,848 (+)Ensemblhg38GRCh38
GRCh37X78,340,425 - 78,341,484 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X78,227,224 - 78,227,548 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX78,580,875 - 78,581,199 (+)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX71,919,624 - 71,920,683 (+)NCBIHuRef
CHM1_1X78,233,671 - 78,234,730 (+)NCBICHM1_1
T2T-CHM13v2.0X77,521,739 - 77,522,798 (+)NCBIT2T-CHM13v2.0
P2ry10b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X106,192,533 - 106,217,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX106,192,533 - 106,217,267 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X107,148,927 - 107,173,661 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX107,148,927 - 107,173,661 (+)Ensemblmm10GRCm38
MGSCv37X104,344,266 - 104,369,000 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X103,352,334 - 103,375,437 (+)NCBIMGSCv36mm8
CeleraX93,993,069 - 94,017,777 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.45NCBI

Variants

.
Variants in P2ry10b
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:502
Count of miRNA genes:251
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000049779
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat

Markers in Region
AI662791  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X72,280,359 - 72,280,463 (+)MAPPERmRatBN7.2
Rnor_6.0X78,283,793 - 78,283,896NCBIRnor6.0
Rnor_5.0X78,481,616 - 78,481,719UniSTSRnor5.0
RGSC_v3.4X95,430,865 - 95,430,968UniSTSRGSC3.4
CeleraX73,574,577 - 73,574,680UniSTS
Cytogenetic MapXq31UniSTS
AU049663  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X72,281,087 - 72,281,235 (+)MAPPERmRatBN7.2
Rnor_6.0X78,284,521 - 78,284,668NCBIRnor6.0
Rnor_5.0X78,482,344 - 78,482,491UniSTSRnor5.0
RGSC_v3.4X95,431,593 - 95,431,740UniSTSRGSC3.4
CeleraX73,575,305 - 73,575,452UniSTS
Cytogenetic MapXq31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 11 67 163 91 90 59 92 59 6 349 191 11 138 76 85 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000049779   ⟹   ENSRNOP00000041147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX76,328,410 - 76,353,564 (+)Ensembl
mRatBN7.2 EnsemblX72,255,542 - 72,280,738 (+)Ensembl
Rnor_6.0 EnsemblX78,259,409 - 78,284,180 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094095   ⟹   ENSRNOP00000095015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX76,328,855 - 76,353,406 (+)Ensembl
mRatBN7.2 EnsemblX72,255,510 - 72,281,012 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098031   ⟹   ENSRNOP00000080765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX76,328,407 - 76,353,406 (+)Ensembl
mRatBN7.2 EnsemblX72,255,636 - 72,281,012 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098290   ⟹   ENSRNOP00000093628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX72,267,372 - 72,281,012 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100884   ⟹   ENSRNOP00000092063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX76,329,103 - 76,351,983 (+)Ensembl
mRatBN7.2 EnsemblX72,255,612 - 72,280,660 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108143   ⟹   ENSRNOP00000083248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX72,273,846 - 72,281,012 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108579   ⟹   ENSRNOP00000088144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX76,328,523 - 76,353,553 (+)Ensembl
mRatBN7.2 EnsemblX72,238,713 - 72,281,012 (+)Ensembl
RefSeq Acc Id: NM_001106939   ⟹   NP_001100409
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X76,329,089 - 76,353,571 (+)NCBI
mRatBN7.2X72,256,265 - 72,280,747 (+)NCBI
Rnor_6.0X78,259,409 - 78,284,180 (+)NCBI
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBI
RGSC_v3.4X95,406,770 - 95,431,252 (+)RGD
CeleraX73,550,447 - 73,574,964 (+)RGD
Sequence:
RefSeq Acc Id: XM_006257166   ⟹   XP_006257228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X76,328,434 - 76,353,570 (+)NCBI
mRatBN7.2X72,255,526 - 72,281,013 (+)NCBI
Rnor_6.0X78,258,495 - 78,284,174 (+)NCBI
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006257168   ⟹   XP_006257230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X76,329,020 - 76,353,570 (+)NCBI
mRatBN7.2X72,256,196 - 72,281,013 (+)NCBI
Rnor_6.0X78,259,312 - 78,284,174 (+)NCBI
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006257169   ⟹   XP_006257231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X76,328,830 - 76,353,570 (+)NCBI
mRatBN7.2X72,256,013 - 72,281,013 (+)NCBI
Rnor_6.0X78,259,029 - 78,284,174 (+)NCBI
Rnor_5.0X78,456,512 - 78,482,003 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099588   ⟹   XP_038955516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X76,340,098 - 76,353,570 (+)NCBI
mRatBN7.2X72,266,378 - 72,281,013 (+)NCBI
RefSeq Acc Id: NP_001100409   ⟸   NM_001106939
- UniProtKB: D3ZQF7 (UniProtKB/TrEMBL),   A6IV62 (UniProtKB/TrEMBL),   A0A8I6AGG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257228   ⟸   XM_006257166
- Peptide Label: isoform X1
- UniProtKB: D3ZQF7 (UniProtKB/TrEMBL),   A6IV62 (UniProtKB/TrEMBL),   A0A8I6AGG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257231   ⟸   XM_006257169
- Peptide Label: isoform X1
- UniProtKB: D3ZQF7 (UniProtKB/TrEMBL),   A6IV62 (UniProtKB/TrEMBL),   A0A8I6AGG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257230   ⟸   XM_006257168
- Peptide Label: isoform X1
- UniProtKB: D3ZQF7 (UniProtKB/TrEMBL),   A6IV62 (UniProtKB/TrEMBL),   A0A8I6AGG3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000041147   ⟸   ENSRNOT00000049779
RefSeq Acc Id: XP_038955516   ⟸   XM_039099588
- Peptide Label: isoform X1
- UniProtKB: D3ZQF7 (UniProtKB/TrEMBL),   A6IV62 (UniProtKB/TrEMBL),   A0A8I6AGG3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080765   ⟸   ENSRNOT00000098031
Ensembl Acc Id: ENSRNOP00000095015   ⟸   ENSRNOT00000094095
Ensembl Acc Id: ENSRNOP00000088144   ⟸   ENSRNOT00000108579
Ensembl Acc Id: ENSRNOP00000092063   ⟸   ENSRNOT00000100884
Ensembl Acc Id: ENSRNOP00000093628   ⟸   ENSRNOT00000098290
Ensembl Acc Id: ENSRNOP00000083248   ⟸   ENSRNOT00000108143
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQF7-F1-model_v2 AlphaFold D3ZQF7 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560455 AgrOrtholog
BioCyc Gene G2FUF-1896 BioCyc
Ensembl Genes ENSRNOG00000037838 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049779.5 UniProtKB/TrEMBL
  ENSRNOT00000094095.2 UniProtKB/TrEMBL
  ENSRNOT00000098031 ENTREZGENE
  ENSRNOT00000098031.2 UniProtKB/TrEMBL
  ENSRNOT00000100884 ENTREZGENE
  ENSRNOT00000100884.2 UniProtKB/TrEMBL
  ENSRNOT00000108579 ENTREZGENE
  ENSRNOT00000108579.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
KEGG Report rno:302377 UniProtKB/TrEMBL
NCBI Gene 302377 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PURINERGIC RECEPTOR P2Y, G-PROTEIN-COUPLED 10B UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen P2ry10b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  P2YPURNOCPTR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000037838 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6AGG3 ENTREZGENE, UniProtKB/TrEMBL
  A6IV62 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQF7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-05 P2ry10b  P2Y receptor family member 10B  P2ry10b  purinergic receptor P2Y, G-protein coupled 10B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-28 P2ry10b  purinergic receptor P2Y, G-protein coupled 10B  RGD1560455  similar to RIKEN cDNA A630033H20 gene  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1560455  similar to RIKEN cDNA A630033H20 gene   RGD1560455_predicted  similar to RIKEN cDNA A630033H20 gene (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560455_predicted  similar to RIKEN cDNA A630033H20 gene (predicted)  LOC302377  similar to RIKEN cDNA A630033H20 gene  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302377  similar to RIKEN cDNA A630033H20 gene      Symbol and Name status set to provisional 70820 PROVISIONAL