Gene: Klhl34 (kelch-like family member 34) Rattus norvegicus
Analyze
Symbol:
Klhl34
Name:
kelch-like family member 34
RGD ID:
1560439
Description:
Orthologous to human KLHL34 (kelch like family member 34); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paracetamol; 4,4'-sulfonyldiphenol (ortholog).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
kelch-like 34; kelch-like 34 (Drosophila); kelch-like protein 34; LOC302703; RGD1560439; similar to hypothetical protein FLJ34960
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 40,966,366 - 40,969,121 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl X 40,965,659 - 40,968,796 (-) Ensembl GRCr8 mRatBN7.2 X 37,151,298 - 37,154,053 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 37,151,592 - 37,153,529 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx X 38,338,155 - 38,340,910 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 41,805,347 - 41,808,102 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 39,490,064 - 39,492,819 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 39,952,576 - 39,956,856 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 39,954,904 - 39,956,841 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 X 40,262,136 - 40,266,740 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 X 58,443,590 - 58,445,527 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera X 37,782,912 - 37,787,192 (-) NCBI Celera Cytogenetic Map X q21 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Klhl34 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO KLHL34 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of KLHL34 mRNA CTD PMID:22298810 Klhl34 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KLHL34 mRNA CTD PMID:33387578 Klhl34 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of KLHL34 mRNA CTD PMID:22298810 Klhl34 Rat 4,4'-sulfonyldiphenol increases expression ISO Klhl34 (Mus musculus) 6480464 bisphenol S results in increased expression of KLHL34 mRNA CTD PMID:30951980 Klhl34 Rat aflatoxin B1 decreases methylation ISO KLHL34 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of KLHL34 5' UTR CTD PMID:30157460 Klhl34 Rat benzo[a]pyrene decreases methylation ISO KLHL34 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of KLHL34 exon CTD PMID:27901495 Klhl34 Rat benzo[a]pyrene affects methylation ISO KLHL34 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of KLHL34 5' UTR; Benzo(a)pyrene affects the methylation of KLHL34 promoter CTD PMID:27901495|PMID:30157460 Klhl34 Rat bisphenol A decreases methylation ISO Klhl34 (Mus musculus) 6480464 bisphenol A results in decreased methylation of KLHL34 promoter CTD PMID:27312807 Klhl34 Rat ethanol increases expression ISO Klhl34 (Mus musculus) 6480464 Ethanol results in increased expression of KLHL34 mRNA CTD PMID:30319688 Klhl34 Rat niclosamide decreases expression ISO KLHL34 (Homo sapiens) 6480464 Niclosamide results in decreased expression of KLHL34 mRNA CTD PMID:36318118 Klhl34 Rat paracetamol increases expression ISO KLHL34 (Homo sapiens) 6480464 Acetaminophen results in increased expression of KLHL34 mRNA CTD PMID:26690555 Klhl34 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of KLHL34 mRNA CTD PMID:33387578 Klhl34 Rat sodium arsenite decreases methylation ISO KLHL34 (Homo sapiens) 6480464 sodium arsenite results in decreased methylation of KLHL34 gene CTD PMID:24570342 Klhl34 Rat valproic acid increases methylation ISO KLHL34 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of KLHL34 gene CTD PMID:29154799
References
Additional References at PubMed
Genomics
Comparative Map Data
Klhl34 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 40,966,366 - 40,969,121 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl X 40,965,659 - 40,968,796 (-) Ensembl GRCr8 mRatBN7.2 X 37,151,298 - 37,154,053 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 37,151,592 - 37,153,529 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx X 38,338,155 - 38,340,910 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 41,805,347 - 41,808,102 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 39,490,064 - 39,492,819 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 39,952,576 - 39,956,856 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 39,954,904 - 39,956,841 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 X 40,262,136 - 40,266,740 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 X 58,443,590 - 58,445,527 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera X 37,782,912 - 37,787,192 (-) NCBI Celera Cytogenetic Map X q21 NCBI
KLHL34 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 21,654,690 - 21,658,330 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 21,654,690 - 21,658,330 (-) Ensembl hg38 GRCh38 GRCh37 X 21,672,808 - 21,676,448 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 21,583,530 - 21,586,369 (-) NCBI Build 36 Build 36 hg18 NCBI36 Celera X 25,794,508 - 25,797,347 (-) NCBI Celera Cytogenetic Map X p22.12 NCBI HuRef X 19,415,982 - 19,418,607 (-) NCBI HuRef CHM1_1 X 21,704,026 - 21,706,865 (-) NCBI CHM1_1 T2T-CHM13v2.0 X 21,238,012 - 21,241,652 (-) NCBI T2T-CHM13v2.0
Klhl34 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 156,600,919 - 156,603,658 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 156,601,431 - 156,603,365 (+) Ensembl GRCm39 Ensembl GRCm39 GRCm38 X 157,818,435 - 157,821,060 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 157,818,435 - 157,820,369 (+) Ensembl mm10 GRCm38 MGSCv37 X 154,256,367 - 154,258,301 (+) NCBI MGSCv37 MGSCv37 mm9 NCBIm37 MGSCv36 X 153,162,191 - 153,165,165 (+) NCBI MGSCv36 mm8 Celera X 141,068,737 - 141,070,671 (+) NCBI Celera Cytogenetic Map X F4 NCBI cM Map X 72.76 NCBI
Klhl34 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955509 1,988,613 - 1,990,553 (-) Ensembl ChiLan1.0 NW_004955509 1,985,511 - 1,990,569 (-) NCBI ChiLan1.0 ChiLan1.0
KLHL34 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 23,462,556 - 23,469,630 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 23,465,946 - 23,469,584 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 14,285,938 - 14,291,694 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 21,640,814 - 21,644,494 (-) NCBI PanPan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 21,641,967 - 21,643,901 (-) Ensembl panPan2 panpan1.1
KLHL34 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 17,464,569 - 17,467,749 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 17,465,756 - 17,467,711 (-) Ensembl canFam3 CanFam3.1 ROS_Cfam_1.0 X 17,422,652 - 17,427,179 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 17,425,206 - 17,427,161 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 17,456,923 - 17,461,452 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 17,478,642 - 17,483,162 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 17,538,546 - 17,543,067 (-) NCBI UU_Cfam_GSD_1.0 UU_Cfam_GSD_1.0
Klhl34 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
KLHL34 (Sus scrofa - pig)
KLHL34 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 20,119,366 - 20,125,858 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 20,120,936 - 20,122,867 (-) Ensembl ChlSab1.1 Ensembl chlSab2 Vervet-AGM Vero_WHO_p1.0 NW_023666056 21,983,390 - 21,987,933 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Klhl34 (Heterocephalus glaber - naked mole-rat)
Klhl34 (Rattus rattus - black rat)
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 31 Count of miRNA genes: 29 Interacting mature miRNAs: 31 Transcripts: ENSRNOT00000050708 Prediction methods: Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction