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Gene: Pnma8b (PNMA family member 8B) Rattus norvegicus

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Symbol:

Pnma8b

Name:

PNMA family member 8B

RGD ID:

1560435

Description:

Orthologous to human PNMA8B (PNMA family member 8B); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC308393; paraneoplastic antigen-like protein 8B; paraneoplastic Ma antigen family member 8B; paraneoplastic Ma antigen family-like 2; PNMA-like 2; PNMA-like protein 2; Pnmal2; RGD1560435; similar to KIAA1183 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PNMA8B (PNMA family member 8B)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Pnma8b (PNMA family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PNMA8B (PNMA family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC102151617 (paraneoplastic Ma antigen family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PNMA8B (PNMA family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PNMA8B (PNMA family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pnma8b (PNMA family member 8B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TMEM106A (transmembrane protein 106A)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Pnma8b (PNMA family member 8B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PNMA8B (PNMA family member 8B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PNMA8B (PNMA family member 8B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,749,840 - 86,754,605 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,748,610 - 86,767,756 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,622,287 - 77,626,525 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,622,283 - 77,627,148 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	83,002,565 - 83,005,139 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,566,634 - 91,569,208 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,757,679 - 84,760,253 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,876,205 - 78,878,779 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,876,205 - 78,878,779 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,123,763 - 80,126,337 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,277,342 - 77,279,916 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	72,107,454 - 72,110,028 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4-hydroxyphenyl retinamide (ISO)

acrylamide (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cocaine (EXP)

dibutyl phthalate (EXP)

ethanol (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glycidol (EXP)

iron dichloride (ISO)

lead(0) (ISO)

methylphenidate (ISO)

paracetamol (EXP)

paraquat (EXP)

perfluorooctanoic acid (EXP)

pioglitazone (ISO)

pirinixic acid (ISO)

silicon dioxide (ISO)

Soman (EXP)

sunitinib (ISO)

testosterone (EXP)

titanium dioxide (ISO)

vinclozolin (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22871113

Genomics

Comparative Map Data

Pnma8b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,749,840 - 86,754,605 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,748,610 - 86,767,756 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,622,287 - 77,626,525 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,622,283 - 77,627,148 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	83,002,565 - 83,005,139 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,566,634 - 91,569,208 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,757,679 - 84,760,253 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	78,876,205 - 78,878,779 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	78,876,205 - 78,878,779 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,123,763 - 80,126,337 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,277,342 - 77,279,916 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	72,107,454 - 72,110,028 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

PNMA8B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	46,491,191 - 46,495,867 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	46,486,906 - 46,495,879 (-)	Ensembl			hg38	GRCh38
GRCh37	19	46,994,448 - 46,999,124 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	51,686,288 - 51,691,009 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	43,797,978 - 43,802,699 (-)	NCBI		Celera
Cytogenetic Map	19	q13.32	NCBI
HuRef	19	43,419,706 - 43,424,427 (-)	NCBI		HuRef
CHM1_1	19	46,996,320 - 47,001,041 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	49,316,813 - 49,321,489 (-)	NCBI		T2T-CHM13v2.0

Pnma8b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	16,678,607 - 16,682,753 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	16,678,607 - 16,682,753 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	16,944,682 - 16,948,828 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	16,944,682 - 16,948,828 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	17,530,031 - 17,532,427 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	16,103,204 - 16,105,600 (+)	NCBI		MGSCv36	mm8
Celera	7	14,151,090 - 14,153,486 (+)	NCBI		Celera
Cytogenetic Map	7	A2	NCBI
cM Map	7	9.15	NCBI

PNMA8B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	52,638,960 - 52,643,614 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	54,509,770 - 54,513,808 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	43,481,590 - 43,485,630 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	52,010,305 - 52,014,887 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	52,011,493 - 52,014,431 (-)	Ensembl			panPan2	panpan1.1

LOC102151617
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	109,332,057 - 109,333,493 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	108,809,914 - 108,812,184 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	109,856,745 - 109,858,650 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UU_Cfam_GSD_1.0	1	110,036,600 - 110,038,905 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

PNMA8B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	52,481,545 - 52,494,700 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PNMA8B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	39,869,687 - 39,873,799 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	39,871,412 - 39,873,316 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	19,552,807 - 19,556,909 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pnma8b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	172,142,912 - 172,145,890 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pnma8b
28 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	43
Count of miRNA genes:	35
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000022610
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	83	82	51	51	51	6	307	151	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_199369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022610 ⟹ ENSRNOP00000022610

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,750,379 - 86,767,756 (+)	Ensembl
mRatBN7.2 Ensembl	1	77,622,283 - 77,627,148 (+)	Ensembl
Rnor_6.0 Ensembl	1	78,876,205 - 78,878,779 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000123642 ⟹ ENSRNOP00000112537

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,748,610 - 86,767,756 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000158141 ⟹ ENSRNOP00000110844

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,748,610 - 86,767,756 (+)	Ensembl

RefSeq Acc Id:

NM_001107481 ⟹ NP_001100951

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,750,447 - 86,753,021 (+)	NCBI
mRatBN7.2	1	77,622,356 - 77,624,930 (+)	NCBI
Rnor_6.0	1	78,876,205 - 78,878,779 (+)	NCBI
Rnor_5.0	1	80,123,763 - 80,126,337 (+)	NCBI
RGSC_v3.4	1	77,277,342 - 77,279,916 (+)	RGD
Celera	1	72,107,454 - 72,110,028 (+)	RGD

Sequence:

show sequence

CCGCGGGAGCACAGGCGAGCCGCTGCTCCCACCCACCCCACGCCCACCAGGTGCATTGATTGCC
GTCCTCCTGTACCCCACCAGCCGCGTCCAGTCGTCTGGGTTGTCAGGGACAAAGGGAGGAACAA
CCCGGGCCAGCCCGGAGAACGTACACGTAAGCCCCCTGCAGACCCTCGGATTGCCCCAGGGGAA
GATCGTTGCGTCGTCCCGCTAGATAGCAGGTAGCTAAAACCCAGAGCCCCAAACCCGAGTCTGG
ACTCTCACCCTGCGGGTGGCCTTTCCAGAGTGGGTTTGACCTAGCCTTTCTCGGGCTCCCTCCC
GCCCAAGATTAGCCTCTGCCAGGCAGCGCCATGACTATGAACCTTCTGCAAGATTGGTGTAAGG
AGCTGGAAGTGGAGGTGCACAGGGCCCTCCTGATCACGGGCATCCCCGAGCGCCTGCAGCAGGC
GGACATCGAAGCTACCCTGAGGCCGAACTTGCAGCCCCTGGGCAACTACAGGCTTCGAACTGTG
AGAGCCGTGACCAAGGAGAAGGCTCAGGCCGCCCTTGTTGAATTTGGGGCCGACTTCGATCACT
CTGCCATACCTATCCACATTAGGGGAGAGAATGGGATCTGGAAAATCCTGAGTAAGGACCGCGG
GCAAGATGCGCGGGTCCTTAGGCAGATGAGGCGCCTGTTGCTGGATGAAAGGCCCATGGATGAC
TTCAGAGAAATTGCCATCCCTCTGGTATTGGAGGCCCAGGCCCAGGCCAAGGGATTAGGGAAGG
AGGCCAAGAAAGCTGGCTCCTCTGAAGGGGCAGCTAGGAGCGGCCGTCGGGGCCGTCGGGGAGG
TAAGCGGCGATCCAGAAGCCACAAGTTGACGGCTCAGAAGGGCCAGAAGAGGAGCCGGGGAGGA
CGCCGAGCCAGGAGTGAGTCGGAAGACTCTTCTGATGACAGCCTGGGTATCGTCATAGAGGAGA
TCTACGCAGAGGACCTGAGCGTAGATGAAGACCAGAGAGCCCTGTATGCCACACTCCAAGCAGC
CGCCAAAGAGCTCACCAAGAAGTGGGCCTTTCGGGGTGACCAGGACGAAGGAGATGGCCCCCGA
GAGTTTTTGGCACTTGTCACGGTCACCGACAAAGCTAAAAAGGAAGAGATAGAGAAAGACCTTC
CTGGGACAGAATCTATTTGCTTAAACATCAAAGACGAAAAGAGCGGGGTCCCTGATTTAGTCGC
GCTACTGGCTGTGAGAGATACCCCCGCAGTGGAGGTAGAAACAGAAGTGGAGGATGATGATGAA
GAAGATGACGATGATGACGATGATGAAGACGAAGATGAAGACGAAGATGATGACGAAGATGACG
ATGACGATGGTTCCGACAGCGAGTCTCTGGAAAATGGAGAGCAAGGGAAGGAAGTAATGGACAG
CCCCGAGTTTGTGGCTATCGTGGCTTATACAGACCCCGCCGACCCGTCTGCCAGAGAAGAAATG
CTGAAAATCGCTTCTGTGATTGAGACCCTCGGTTGGGGCGATAAAAAAGACAAAAAAGATGTCC
TTCCTCAAGTCCTGTCCGTCATGGCCAAGGACACCTCTGGGCCCAGGGTGAAGGTAGAAGAGGC
AGGTCGCCAGGTGGACGCCATGGTTCTGAGGAAGGCAGAGGAAGATGGGAATCTTCTGGAATGT
ATTTCCACCTTGGCTGAAGCAGAGAACTGCCCTAAAGGAAAGAAATCTGGGCTAGGTCTCCTCA
GAGGCTGGACCGCTGAGGGCCACCAGGGTGGCCTCTTGGAGCTGGTGGCACTCCTGGCTGCTCA
AGATATGGTGGAAGCTGTGAGAGAGGAAGAAGCCAGCAGGTGGGGCGGTGGTGGAAGTGGTGGC
CGGAAGTGTGATCACAGCCAAGGTGGTTTATCCGAGGTCCTGGCTTTCCTGGCCTCCCAGGAGA
ATCTCGAATCCAACGAGGAATCGGAGGAAGATTCAGACACAGAGTCAGAGGGAGATTCCGAGGA
CACTGACAGCGAAGAGTCAGAACCTGGTGACAGCGTGTCCAAGAAGCCGCGCGCCAAGAGAGCG
CGCACCGGCTCCAAAGGCTTGGCACCGGCCGGCGCCACCGCGGTCTCCACCGGGTCCCGGGCAC
GCAAAACCCGCAGGGGTGGCCGCGGTCGTGGCCGCGGTGTCACCCCAGAGAAGAAAGCGGGGAG
CGGGGCTTCAACCGAGGACCATGCGGGGAACAACAAAAAGAAGAAGAAGAAGGGATCCGCAGGC
GCCGGGGCCCGTGTCAGGGCTGGTGAGGCCAAGGGACAGCCAGCTGCTGTTCCCAAGTCTACCC
GCGGAAAGAAAGCACGCAGGGGCCCAAGGCGGGCGCCCAAATGCCGTTAGTGCCGCAGATGTCA
CTACGAGCCCCGTCTCTTGTGTGTGGACTTCCCCCTTCCCGTTTCCTCCTATTCTCTCTTCTCC
CTGCAGCTTCCCTCTCGCTTAACCGCGTGCATTTGCTTTGTGCTCCGCTGTGTCCCTGGCTGGC
TATGGCCGGTGCCCAGCTTTCCCTCTCAGTTCCATGAACAGATGGCATGAGCGATCATTATGGC
TGCAGCCTAGATACA

hide sequence

RefSeq Acc Id:

XM_039111197 ⟹ XP_038967125

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,749,840 - 86,754,605 (+)	NCBI
mRatBN7.2	1	77,622,287 - 77,626,525 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100951	(Get FASTA)	NCBI Sequence Viewer
	XP_038967125	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08291	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022610.4
	ENSRNOP00000110844.1
	ENSRNOP00000112537
	ENSRNOP00000112537.1

RefSeq Acc Id:

NP_001100951 ⟸ NM_001107481

- UniProtKB:

D3ZQN3 (UniProtKB/TrEMBL), A6J8E3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTMNLLQDWCKELEVEVHRALLITGIPERLQQADIEATLRPNLQPLGNYRLRTVRAVTKEKAQA
ALVEFGADFDHSAIPIHIRGENGIWKILSKDRGQDARVLRQMRRLLLDERPMDDFREIAIPLVL
EAQAQAKGLGKEAKKAGSSEGAARSGRRGRRGGKRRSRSHKLTAQKGQKRSRGGRRARSESEDS
SDDSLGIVIEEIYAEDLSVDEDQRALYATLQAAAKELTKKWAFRGDQDEGDGPREFLALVTVTD
KAKKEEIEKDLPGTESICLNIKDEKSGVPDLVALLAVRDTPAVEVETEVEDDDEEDDDDDDDED
EDEDEDDDEDDDDDGSDSESLENGEQGKEVMDSPEFVAIVAYTDPADPSAREEMLKIASVIETL
GWGDKKDKKDVLPQVLSVMAKDTSGPRVKVEEAGRQVDAMVLRKAEEDGNLLECISTLAEAENC
PKGKKSGLGLLRGWTAEGHQGGLLELVALLAAQDMVEAVREEEASRWGGGGSGGRKCDHSQGGL
SEVLAFLASQENLESNEESEEDSDTESEGDSEDTDSEESEPGDSVSKKPRAKRARTGSKGLAPA
GATAVSTGSRARKTRRGGRGRGRGVTPEKKAGSGASTEDHAGNNKKKKKKGSAGAGARVRAGEA
KGQPAAVPKSTRGKKARRGPRRAPKCR

hide sequence

Ensembl Acc Id:

ENSRNOP00000022610 ⟸ ENSRNOT00000022610

RefSeq Acc Id:	XP_038967125 ⟸ XM_039111197
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000112537 ⟸ ENSRNOT00000123642

Ensembl Acc Id:

ENSRNOP00000110844 ⟸ ENSRNOT00000158141

Protein Domains

Paraneoplastic antigen Ma-like N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZQN3-F1-model_v2	AlphaFold	D3ZQN3	1-667	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689746

Promoter ID:

EPDNEW_R270

Type:

initiation region

Name:

Pnma8b_1

Description:

PNMA family member 8B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	78,876,146 - 78,876,206	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560435	AgrOrtholog
BioCyc Gene	G2FUF-60586	BioCyc
Ensembl Genes	ENSRNOG00000016863	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022610.6	UniProtKB/TrEMBL
	ENSRNOT00000123642	ENTREZGENE
	ENSRNOT00000123642.1	UniProtKB/TrEMBL
	ENSRNOT00000158141.1	UniProtKB/TrEMBL
InterPro	PNMA	UniProtKB/TrEMBL
	PNMA_N	UniProtKB/TrEMBL
KEGG Report	rno:308393	UniProtKB/TrEMBL
NCBI Gene	308393	ENTREZGENE
PANTHER	PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8B	UniProtKB/TrEMBL
	PTHR23095	UniProtKB/TrEMBL
Pfam	PNMA_N	UniProtKB/TrEMBL
PhenoGen	Pnma8b	PhenoGen
RatGTEx	ENSRNOG00000016863	RatGTEx
UniProt	A6J8E3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZQN3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-09-28	Pnma8b	PNMA family member 8B	Pnma8b	paraneoplastic Ma antigen family member 8B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2017-04-05	Pnma8b	paraneoplastic Ma antigen family member 8B	Pnmal2	paraneoplastic Ma antigen family-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-10	Pnmal2	paraneoplastic Ma antigen family-like 2	Pnmal2	PNMA-like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-18	Pnmal2	PNMA-like 2	RGD1560435_predicted	similar to KIAA1183 protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1560435_predicted	similar to KIAA1183 protein (predicted)	LOC308393	similar to KIAA1183 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC308393	similar to KIAA1183 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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