C12h12orf76 (similar to human chromosome 12 open reading frame 76) - Rat Genome Database

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Gene: C12h12orf76 (similar to human chromosome 12 open reading frame 76) Rattus norvegicus
Analyze
Symbol: C12h12orf76
Name: similar to human chromosome 12 open reading frame 76
RGD ID: 1560398
Description: Predicted to be located in membrane. Orthologous to human C12orf76 (chromosome 12 open reading frame 76); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paracetamol; tetrachloromethane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498192; RGD1560398; RGD1560398; uncharacterized protein C12orf76 homolog; uncharacterized protein LOC498192; uncharacterized protein RGD1560398
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,452,148 - 47,456,832 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1247,452,016 - 47,456,829 (+)EnsemblGRCr8
mRatBN7.21241,791,339 - 41,796,200 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,791,359 - 41,796,200 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1242,959,554 - 42,964,206 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,573,132 - 43,577,784 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,633,622 - 42,638,274 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,551,749 - 47,556,597 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,551,935 - 47,555,589 (+)Ensemblrn6Rnor6.0
Rnor_5.01249,345,290 - 49,350,123 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,079,302 - 43,083,714 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,406,871 - 43,411,718 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
C12h12orf76
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81247,452,148 - 47,456,832 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1247,452,016 - 47,456,829 (+)EnsemblGRCr8
mRatBN7.21241,791,339 - 41,796,200 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,791,359 - 41,796,200 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1242,959,554 - 42,964,206 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01243,573,132 - 43,577,784 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,633,622 - 42,638,274 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,551,749 - 47,556,597 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,551,935 - 47,555,589 (+)Ensemblrn6Rnor6.0
Rnor_5.01249,345,290 - 49,350,123 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41243,079,302 - 43,083,714 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1243,406,871 - 43,411,718 (+)NCBICelera
Cytogenetic Map12q16NCBI
C12orf76
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812110,041,177 - 110,073,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12110,027,028 - 110,073,636 (-)Ensemblhg38GRCh38
GRCh3712110,478,982 - 110,511,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,963,366 - 108,989,883 (-)NCBIBuild 36Build 36hg18NCBI36
Celera12110,103,217 - 110,129,734 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,494,988 - 107,521,516 (-)NCBIHuRef
CHM1_112110,446,778 - 110,473,305 (-)NCBICHM1_1
T2T-CHM13v2.012110,016,870 - 110,049,334 (-)NCBIT2T-CHM13v2.0
1500011B03Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,946,257 - 114,952,037 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,946,257 - 114,961,529 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385114,808,196 - 114,813,976 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,808,196 - 114,823,468 (-)Ensemblmm10GRCm38
MGSCv375115,258,205 - 115,263,985 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365115,258,205 - 115,263,985 (-)NCBIMGSCv36mm8
Celera5111,906,373 - 111,912,155 (-)NCBICelera
Cytogenetic Map5FNCBI
LOC100981975
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210118,116,967 - 118,140,248 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112118,112,541 - 118,136,653 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012107,603,458 - 107,649,324 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112111,011,517 - 111,030,557 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,998,926 - 111,035,322 (-)EnsemblpanPan2panpan1.1
LOC102152728
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,127,123 - 17,132,938 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,669,277 - 18,674,903 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02617,471,758 - 17,477,387 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.12618,878,836 - 18,884,457 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02617,461,552 - 17,467,176 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02617,479,000 - 17,484,628 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100517973
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11440,943,932 - 40,950,610 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,461,576 - 43,468,246 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C11H12orf76
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,280,363 - 105,306,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037139,814,515 - 139,838,712 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:83
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000056932
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)124413955852308831Rat

Markers in Region
RH143018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21241,792,598 - 41,792,849 (+)MAPPERmRatBN7.2
Rnor_6.01247,552,992 - 47,553,242NCBIRnor6.0
Rnor_5.01249,346,518 - 49,346,768UniSTSRnor5.0
RGSC_v3.41243,080,530 - 43,080,780UniSTSRGSC3.4
Celera1243,408,113 - 43,408,363UniSTS
RH 3.4 Map12779.73UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 67 164 91 90 59 90 59 6 352 190 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000056932   ⟹   ENSRNOP00000053770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1247,551,935 - 47,555,589 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114141   ⟹   ENSRNOP00000088363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1247,452,016 - 47,456,829 (+)Ensembl
mRatBN7.2 Ensembl1241,791,359 - 41,796,200 (+)Ensembl
RefSeq Acc Id: NM_001417147   ⟹   NP_001404076
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81247,452,148 - 47,456,832 (+)NCBI
mRatBN7.21241,791,513 - 41,796,200 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001404076 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13922 (Get FASTA)   NCBI Sequence Viewer  
  EDM13923 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088363
  ENSRNOP00000088363.2
Ensembl Acc Id: ENSRNOP00000053770   ⟸   ENSRNOT00000056932
Ensembl Acc Id: ENSRNOP00000088363   ⟸   ENSRNOT00000114141
RefSeq Acc Id: NP_001404076   ⟸   NM_001417147
- Peptide Label: precursor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZH37-F1-model_v2 AlphaFold D3ZH37 1-72 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698711
Promoter ID:EPDNEW_R9231
Type:initiation region
Name:RGD1560398_1
Description:RGD1560398
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01247,551,931 - 47,551,991EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560398 AgrOrtholog
BioCyc Gene G2FUF-18961 BioCyc
Ensembl Genes ENSRNOG00000037566 Ensembl
  ENSRNOG00000069648 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000114141 ENTREZGENE
  ENSRNOT00000114141.2 UniProtKB/TrEMBL
InterPro Viral_Envelope_Glycoprotein UniProtKB/TrEMBL
NCBI Gene 498192 ENTREZGENE
PANTHER RIKEN CDNA 1500011B03 GENE UniProtKB/TrEMBL
  RIKEN CDNA 1500011B03 GENE-RELATED UniProtKB/TrEMBL
PhenoGen C12h12orf76 PhenoGen
RatGTEx ENSRNOG00000037566 RatGTEx
  ENSRNOG00000069648 RatGTEx
UniProt A0A8I6A9N4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C12h12orf76  similar to human chromosome 12 open reading frame 76  RGD1560398  RGD1560398  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560398  RGD1560398   RGD1560398_predicted  RGD1560398 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560398_predicted  RGD1560398 (predicted)  LOC498192  LOC498192  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498192  LOC498192      Symbol and Name status set to provisional 70820 PROVISIONAL