Vom2r36 (vomeronasal 2 receptor, 36) - Rat Genome Database

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Gene: Vom2r36 (vomeronasal 2 receptor, 36) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r36 (Ensembl: Vom2r35)
Name: vomeronasal 2 receptor, 36 (Ensembl:vomeronasal 2 receptor, 35)
RGD ID: 1560365
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane; INTERACTS WITH 1,2-dimethylhydrazine; acrylamide; trichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC502301; RGD1560365; similar to Ca(2+)-sensing receptor; vomeronasal 2 receptor 36
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8182,339,767 - 82,366,277 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.2173,268,795 - 73,294,065 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl173,073,396 - 73,106,385 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl173,167,047 - 73,293,895 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx178,683,606 - 78,698,337 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0187,247,964 - 87,262,695 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0180,438,677 - 80,453,406 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd181,854,488 - 81,869,211 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive185,559,702 - 85,574,489 (-)NCBILyon_Normotensive
Lyon_Hypertensive183,396,417 - 83,411,205 (-)NCBILyon_Hypertensive
F344_StmMcwi180,515,578 - 80,530,365 (-)NCBIF344_StmMcwi
Rnor_6.0165,906,344 - 66,166,365 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl165,906,344 - 66,159,639 (+)Ensemblrn6Rnor6.0
Rnor_5.0166,931,471 - 66,959,011 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4173,171,753 - 73,187,418 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera160,519,851 - 60,534,634 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r36
230 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
1 3 24 18 12 7 3 7 1 38 14 2 17 16 23 5

Sequence


Ensembl Acc Id: ENSRNOT00000042276   ⟹   ENSRNOP00000044564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl173,210,417 - 73,227,703 (-)Ensembl
Rnor_6.0 Ensembl166,004,349 - 66,021,670 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000052029   ⟹   ENSRNOP00000039009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl173,268,171 - 73,293,895 (-)Ensembl
Rnor_6.0 Ensembl166,004,352 - 66,021,670 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000068611   ⟹   ENSRNOP00000059911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl173,167,047 - 73,283,580 (-)Ensembl
Rnor_6.0 Ensembl165,906,344 - 66,159,639 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107882   ⟹   ENSRNOP00000092905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl173,268,171 - 73,293,895 (-)Ensembl
RefSeq Acc Id: NM_001099483   ⟹   NP_001092953
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8182,340,977 - 82,355,766 (-)NCBI
mRatBN7.2173,268,795 - 73,283,580 (-)NCBI
Dahl_SR_JrHsd181,854,488 - 81,869,211 (-)NCBI
Lyon_Normotensive185,559,702 - 85,574,489 (-)NCBI
Lyon_Hypertensive183,396,417 - 83,411,205 (-)NCBI
F344_StmMcwi180,515,578 - 80,530,365 (-)NCBI
Rnor_6.0165,906,344 - 66,159,639 (+)NCBI
Rnor_5.0166,931,471 - 66,959,011 (+)NCBI
RGSC_v3.4173,171,753 - 73,187,418 (-)RGD
Celera160,519,851 - 60,534,634 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088257   ⟹   XP_038944185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8182,339,767 - 82,366,277 (-)NCBI
mRatBN7.2173,268,795 - 73,294,065 (-)NCBI
RefSeq Acc Id: XM_063271848   ⟹   XP_063127918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8182,339,767 - 82,366,277 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001092953 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944185 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127918 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000039009
  ENSRNOP00000039009.6
  ENSRNOP00000064572.4
RefSeq Acc Id: NP_001092953   ⟸   NM_001099483
- Sequence:
Ensembl Acc Id: ENSRNOP00000059911   ⟸   ENSRNOT00000068611
Ensembl Acc Id: ENSRNOP00000044564   ⟸   ENSRNOT00000042276
Ensembl Acc Id: ENSRNOP00000039009   ⟸   ENSRNOT00000052029
RefSeq Acc Id: XP_038944185   ⟸   XM_039088257
- Peptide Label: isoform X1
- UniProtKB: M0R5A8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092905   ⟸   ENSRNOT00000107882
RefSeq Acc Id: XP_063127918   ⟸   XM_063271848
- Peptide Label: isoform X2
- UniProtKB: D3ZQW6 (UniProtKB/TrEMBL),   M0R5A8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M1S0-F1-model_v2 AlphaFold F1M1S0 1-788 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560365 AgrOrtholog
BioCyc Gene G2FUF-60724 BioCyc
Ensembl Genes ENSRNOG00000048663 Ensembl
  ENSRNOG00000050831 Ensembl
  ENSRNOG00000082565 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000090188 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052029 ENTREZGENE
  ENSRNOT00000052029.7 UniProtKB/TrEMBL
  ENSRNOT00000074234.4 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_Ca_sens_rcpt-rel UniProtKB/TrEMBL
  GPCR_3_CS UniProtKB/TrEMBL
  GPCR_3_vmron_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene 502301 ENTREZGENE
PANTHER PTHR24061 UniProtKB/TrEMBL
  VOMERONASAL 2, RECEPTOR 53-RELATED UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PhenoGen Vom2r36 PhenoGen
PRINTS GPCRMGR UniProtKB/TrEMBL
  VOMERONASL2R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048663 RatGTEx
  ENSRNOG00000050831 RatGTEx
  ENSRNOG00000082565 RatGTEx
  ENSRNOG00000090188 RatGTEx
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt D3ZQW6 ENTREZGENE, UniProtKB/TrEMBL
  M0R5A8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-07-23 Vom2r36  vomeronasal 2 receptor, 36  RGD1560365  similar to Ca(2+)-sensing receptor   Symbol and Name updated 1299863 APPROVED
2008-04-30 RGD1560365  similar to Ca(2+)-sensing receptor   RGD1560365_predicted  similar to Ca(2+)-sensing receptor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560365_predicted  similar to Ca(2+)-sensing receptor (predicted)  LOC502301  similar to Ca(2+)-sensing receptor  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502301  similar to Ca(2+)-sensing receptor      Symbol and Name status set to provisional 70820 PROVISIONAL