Cldn2 (claudin 2) - Rat Genome Database

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Gene: Cldn2 (claudin 2) Rattus norvegicus
Analyze
Symbol: Cldn2
Name: claudin 2
RGD ID: 1560247
Description: Predicted to enable identical protein binding activity and paracellular tight junction channel activity. Predicted to be involved in several processes, including bicellular tight junction assembly; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; and regulation of intestinal absorption. Predicted to be located in tight junction. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN2 (claudin 2); PARTICIPATES IN hepatitis C pathway; INTERACTS WITH (R,R,R)-alpha-tocopherol; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: claudin-2; LOC300920; RGD1560247; similar to claudin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X108,248,383 - 108,258,847 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX108,237,676 - 108,262,377 (+)EnsemblGRCr8
mRatBN7.2X103,459,870 - 103,473,794 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX103,459,780 - 103,474,838 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX105,592,416 - 105,602,750 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X109,091,151 - 109,101,485 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X106,655,156 - 106,665,516 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X111,122,552 - 111,133,188 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX111,122,552 - 111,137,769 (+)Ensemblrn6Rnor6.0
Rnor_5.0353,456,573 - 53,472,568 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X127,538,685 - 127,549,019 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera344,457,488 - 44,467,822 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(R,R,R)-alpha-tocopherol  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
acadesine  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
Ammothamnine  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
brequinar  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroquine  (ISO)
cholic acid  (EXP)
cisplatin  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
corticosterone  (ISO)
Cuprizon  (EXP)
curcumin  (EXP)
cyclosporin A  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
diallyl disulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibenzofurans  (ISO)
dieldrin  (EXP)
diiodine  (ISO)
dimethyl sulfoxide  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethylparaben  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gefitinib  (ISO)
genistein  (EXP)
glycidol  (EXP)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
irinotecan  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
isoniazide  (ISO)
kaempferol  (EXP)
lipopolysaccharide  (EXP,ISO)
LY294002  (EXP)
maleic acid  (EXP)
metformin  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodimethylamine  (ISO)
naphthalene  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzenesulfonic acid  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP,ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium bromate  (ISO)
potassium dichromate  (EXP)
Pyridostigmine bromide  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sanguinarine  (ISO)
SB 203580  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
solasodine  (ISO)
streptozocin  (EXP)
sulfasalazine  (EXP)
tamoxifen  (ISO)
tetracycline  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9647647   PMID:10508613   PMID:10562289   PMID:16520537   PMID:17434483   PMID:18036336   PMID:18197414   PMID:19587148   PMID:21415414   PMID:22275141   PMID:23199000  
PMID:23376485   PMID:24726862   PMID:26423859   PMID:33417957   PMID:38512760  


Genomics

Comparative Map Data
Cldn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X108,248,383 - 108,258,847 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX108,237,676 - 108,262,377 (+)EnsemblGRCr8
mRatBN7.2X103,459,870 - 103,473,794 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX103,459,780 - 103,474,838 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX105,592,416 - 105,602,750 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X109,091,151 - 109,101,485 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X106,655,156 - 106,665,516 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X111,122,552 - 111,133,188 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX111,122,552 - 111,137,769 (+)Ensemblrn6Rnor6.0
Rnor_5.0353,456,573 - 53,472,568 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X127,538,685 - 127,549,019 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera344,457,488 - 44,467,822 (-)NCBICelera
Cytogenetic MapXq32NCBI
CLDN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X106,900,164 - 106,930,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX106,900,125 - 106,930,862 (+)Ensemblhg38GRCh38
GRCh37X106,143,394 - 106,174,091 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,050,290 - 106,060,747 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X105,969,778 - 105,980,236NCBI
CeleraX106,614,779 - 106,645,477 (+)NCBICelera
Cytogenetic MapXq22.3NCBI
HuRefX95,771,755 - 95,802,061 (+)NCBIHuRef
CHM1_1X106,054,200 - 106,084,897 (+)NCBICHM1_1
T2T-CHM13v2.0X105,336,674 - 105,367,377 (+)NCBIT2T-CHM13v2.0
Cldn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X138,701,552 - 138,712,135 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX138,701,577 - 138,712,135 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X139,800,808 - 139,811,386 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX139,800,828 - 139,811,386 (+)Ensemblmm10GRCm38
MGSCv37X136,335,367 - 136,345,923 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X135,147,192 - 135,157,748 (+)NCBIMGSCv36mm8
CeleraX123,063,444 - 123,074,101 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.35NCBI
Cldn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554909,136,986 - 9,145,034 (-)Ensembl
ChiLan1.0NW_0049554909,137,157 - 9,180,945 (-)NCBIChiLan1.0ChiLan1.0
CLDN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X106,410,924 - 106,414,386 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X106,414,543 - 106,417,987 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X96,020,274 - 96,031,157 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X106,405,707 - 106,408,516 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX106,405,879 - 106,406,571 (+)EnsemblpanPan2panpan1.1
CLDN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X80,456,313 - 80,491,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX80,483,333 - 80,530,012 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX66,603,000 - 66,603,952 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X82,119,947 - 82,128,336 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1X79,592,206 - 79,593,158 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X81,302,056 - 81,303,008 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X81,081,052 - 81,082,004 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cldn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X79,829,508 - 79,839,529 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364997,820,410 - 7,821,102 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364997,818,436 - 7,828,444 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLDN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX87,321,152 - 87,355,721 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X87,352,695 - 87,355,724 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CLDN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X94,752,552 - 94,762,247 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606519,835,977 - 19,848,312 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cldn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248039,839,911 - 9,846,367 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248039,839,916 - 9,849,891 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cldn2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X92,263,710 - 92,274,304 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cldn2
58 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:425
Count of miRNA genes:248
Interacting mature miRNAs:311
Transcripts:ENSRNOT00000050571
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX92979612117740458Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
Cldn2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X103,467,561 - 103,468,254 (+)MAPPERmRatBN7.2
Rnor_6.0X111,130,501 - 111,131,193NCBIRnor6.0
Rnor_5.0353,463,931 - 53,464,623UniSTSRnor5.0
RGSC_v3.4X127,546,333 - 127,547,025UniSTSRGSC3.4
Celera344,459,482 - 44,460,174UniSTS
Cytogenetic MapXq35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 50 140 85 84 53 34 53 6 271 113 6 117 81 87 31 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000083566   ⟹   ENSRNOP00000075499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,248,370 - 108,259,015 (+)Ensembl
mRatBN7.2 EnsemblX103,459,780 - 103,474,838 (+)Ensembl
Rnor_6.0 EnsemblX111,122,552 - 111,133,191 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085078   ⟹   ENSRNOP00000074756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX111,122,596 - 111,133,186 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090928   ⟹   ENSRNOP00000070587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,256,004 - 108,262,377 (+)Ensembl
mRatBN7.2 EnsemblX103,467,555 - 103,469,038 (+)Ensembl
Rnor_6.0 EnsemblX111,122,671 - 111,137,769 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000134556   ⟹   ENSRNOP00000112625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,237,676 - 108,259,008 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154683   ⟹   ENSRNOP00000098969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,249,646 - 108,258,876 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155259   ⟹   ENSRNOP00000106880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,255,689 - 108,259,008 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157308   ⟹   ENSRNOP00000104358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,248,429 - 108,259,015 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161188   ⟹   ENSRNOP00000102207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,248,561 - 108,258,645 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173184   ⟹   ENSRNOP00000107116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX108,248,519 - 108,258,972 (+)Ensembl
RefSeq Acc Id: NM_001106846   ⟹   NP_001100316
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X108,248,513 - 108,258,847 (+)NCBI
mRatBN7.2X103,459,913 - 103,470,248 (+)NCBI
Rnor_6.0X111,122,596 - 111,133,187 (+)NCBI
Rnor_5.0353,456,573 - 53,472,568 (-)NCBI
RGSC_v3.4X127,538,685 - 127,549,019 (+)RGD
Celera344,457,488 - 44,467,822 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234262   ⟹   XP_006234324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X108,248,383 - 108,258,847 (+)NCBI
mRatBN7.2X103,459,871 - 103,470,250 (+)NCBI
Rnor_6.0X111,122,552 - 111,133,188 (+)NCBI
Rnor_5.0353,456,573 - 53,472,568 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063279887   ⟹   XP_063135957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X108,254,572 - 108,258,847 (+)NCBI
RefSeq Acc Id: NP_001100316   ⟸   NM_001106846
- UniProtKB: D4A386 (UniProtKB/TrEMBL),   A6HLS9 (UniProtKB/TrEMBL),   A0A0G2JYB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234324   ⟸   XM_006234262
- Peptide Label: isoform X1
- UniProtKB: D4A386 (UniProtKB/TrEMBL),   A6HLS9 (UniProtKB/TrEMBL),   A0A0G2JYB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074756   ⟸   ENSRNOT00000085078
Ensembl Acc Id: ENSRNOP00000070587   ⟸   ENSRNOT00000090928
Ensembl Acc Id: ENSRNOP00000075499   ⟸   ENSRNOT00000083566
RefSeq Acc Id: XP_063135957   ⟸   XM_063279887
- Peptide Label: isoform X1
- UniProtKB: A6HLS9 (UniProtKB/TrEMBL),   D4A386 (UniProtKB/TrEMBL),   A0A0G2JYB2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000112625   ⟸   ENSRNOT00000134556
Ensembl Acc Id: ENSRNOP00000098969   ⟸   ENSRNOT00000154683
Ensembl Acc Id: ENSRNOP00000104358   ⟸   ENSRNOT00000157308
Ensembl Acc Id: ENSRNOP00000106880   ⟸   ENSRNOT00000155259
Ensembl Acc Id: ENSRNOP00000107116   ⟸   ENSRNOT00000173184
Ensembl Acc Id: ENSRNOP00000102207   ⟸   ENSRNOT00000161188

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A386-F1-model_v2 AlphaFold D4A386 1-230 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560247 AgrOrtholog
BioCyc Gene G2FUF-1553 BioCyc
Ensembl Genes ENSRNOG00000054495 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083566 ENTREZGENE
  ENSRNOT00000083566.3 UniProtKB/TrEMBL
  ENSRNOT00000090928.3 UniProtKB/TrEMBL
  ENSRNOT00000134556 ENTREZGENE
  ENSRNOT00000134556.1 UniProtKB/TrEMBL
  ENSRNOT00000154683.1 UniProtKB/TrEMBL
  ENSRNOT00000155259.1 UniProtKB/TrEMBL
  ENSRNOT00000157308.1 UniProtKB/TrEMBL
  ENSRNOT00000161188.1 UniProtKB/TrEMBL
  ENSRNOT00000173184.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.140.150 UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  Claudin2 UniProtKB/TrEMBL
  Claudin_CS UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report rno:300920 UniProtKB/TrEMBL
NCBI Gene 300920 ENTREZGENE
PANTHER Claudin UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PhenoGen Cldn2 PhenoGen
PRINTS CLAUDIN UniProtKB/TrEMBL
  CLAUDIN2 UniProtKB/TrEMBL
PROSITE CLAUDIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054495 RatGTEx
UniProt A0A0G2JYB2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LD71_RAT UniProtKB/TrEMBL
  A6HLS9 ENTREZGENE, UniProtKB/TrEMBL
  D4A386 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cldn2  claudin 2   Cldn2_predicted  claudin 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Cldn2_predicted  claudin 2 (predicted)  RGD1560247_predicted  similar to claudin-2 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1560247_predicted  similar to claudin-2 (predicted)  LOC300920  similar to claudin-2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC300920  similar to claudin-2      Symbol and Name status set to provisional 70820 PROVISIONAL