Gene: Srrm4 (serine/arginine repetitive matrix 4) Rattus norvegicus
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Symbol:
Srrm4
Name:
serine/arginine repetitive matrix 4
RGD ID:
1560213
Description:
Predicted to enable identical protein binding activity and mRNA binding activity. Predicted to be involved in mRNA processing; neuron maturation; and regulation of RNA splicing. Predicted to act upstream of or within regulation of alternative mRNA splicing, via spliceosome and sensory perception of sound. Predicted to be active in nucleus. Orthologous to human SRRM4 (serine/arginine repetitive matrix 4); PARTICIPATES IN spliceosome pathway; INTERACTS WITH bisphenol A; cadmium dichloride; dioxygen.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC498189; RGD1560213; serine/arginine repetitive matrix protein 4; similar to RIKEN cDNA 1500001A10
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 12 45,659,729 - 45,819,643 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 12 45,660,450 - 45,816,475 (+) Ensembl GRCr8 mRatBN7.2 12 39,998,975 - 40,158,897 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 12 39,999,488 - 40,155,725 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 12 41,174,282 - 41,331,031 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 12 41,788,111 - 41,944,866 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 12 40,847,885 - 41,005,387 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 12 45,726,192 - 45,884,644 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 12 45,727,112 - 45,882,548 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 12 47,542,208 - 47,700,492 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 12 41,216,421 - 41,373,052 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 12 41,639,982 - 41,795,400 (+) NCBI Celera Cytogenetic Map 12 q16 NCBI
JBrowse:
Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Srrm4 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Srrm4 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Srrm4 Rat 17beta-estradiol increases expression ISO Srrm4 (Mus musculus) 6480464 Estradiol results in increased expression of SRRM4 mRNA CTD PMID:39298647 Srrm4 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Srrm4 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Srrm4 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Srrm4 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Srrm4 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases expression ISO Srrm4 (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in decreased expression of SRRM4 mRNA CTD PMID:31388691 Srrm4 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Srrm4 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Srrm4 Rat 4,4'-sulfonyldiphenol decreases expression ISO Srrm4 (Mus musculus) 6480464 bisphenol S results in decreased expression of SRRM4 mRNA CTD PMID:30951980|PMID:39298647 Srrm4 Rat 4,4'-sulfonyldiphenol affects methylation ISO Srrm4 (Mus musculus) 6480464 bisphenol S affects the methylation of SRRM4 exon; bisphenol S affects the methylation of SRRM4 more ... CTD PMID:31683443|PMID:33297965 Srrm4 Rat 4,4'-sulfonyldiphenol decreases methylation ISO Srrm4 (Mus musculus) 6480464 bisphenol S results in decreased methylation of SRRM4 promoter CTD PMID:33297965 Srrm4 Rat aflatoxin B1 increases expression ISO Srrm4 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of SRRM4 mRNA CTD PMID:19770486 Srrm4 Rat atrazine decreases expression ISO SRRM4 (Homo sapiens) 6480464 Atrazine results in decreased expression of SRRM4 mRNA CTD PMID:22378314 Srrm4 Rat benzo[a]pyrene increases methylation ISO SRRM4 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of SRRM4 promoter CTD PMID:27901495 Srrm4 Rat benzo[b]fluoranthene increases expression ISO Srrm4 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of SRRM4 mRNA CTD PMID:26377693 Srrm4 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SRRM4 mRNA CTD PMID:25181051 Srrm4 Rat bisphenol A decreases methylation ISO SRRM4 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of SRRM4 gene CTD PMID:31601247 Srrm4 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SRRM4 mRNA CTD PMID:30816183|PMID:34947998 Srrm4 Rat bisphenol A increases expression ISO SRRM4 (Homo sapiens) 6480464 bisphenol A results in increased expression of SRRM4 mRNA CTD PMID:29275510 Srrm4 Rat bisphenol F decreases expression ISO Srrm4 (Mus musculus) 6480464 bisphenol F results in decreased expression of SRRM4 mRNA CTD PMID:30951980|PMID:38685157 Srrm4 Rat Butylbenzyl phthalate increases methylation ISO Srrm4 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of SRRM4 intron CTD PMID:28392331 Srrm4 Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SRRM4 mRNA CTD PMID:33453195 Srrm4 Rat carbon nanotube increases expression ISO Srrm4 (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of SRRM4 mRNA CTD PMID:25620056 Srrm4 Rat dibutyl phthalate increases expression ISO Srrm4 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of SRRM4 mRNA CTD PMID:21266533 Srrm4 Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression more ... CTD PMID:33729688 Srrm4 Rat dorsomorphin multiple interactions ISO SRRM4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Srrm4 Rat entinostat decreases expression ISO SRRM4 (Homo sapiens) 6480464 entinostat results in decreased expression of SRRM4 mRNA CTD PMID:27188386 Srrm4 Rat epoxiconazole increases expression ISO Srrm4 (Mus musculus) 6480464 epoxiconazole results in increased expression of SRRM4 mRNA CTD PMID:35436446 Srrm4 Rat furan increases expression ISO Srrm4 (Mus musculus) 6480464 furan results in increased expression of SRRM4 mRNA CTD PMID:24183702 Srrm4 Rat glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of SRRM4 gene CTD PMID:35440735 Srrm4 Rat hydrogen cyanide decreases expression ISO Srrm4 (Mus musculus) 6480464 Hydrogen Cyanide results in decreased expression of SRRM4 mRNA CTD PMID:33914522 Srrm4 Rat inulin multiple interactions ISO Srrm4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SRRM4 mRNA CTD PMID:36331819 Srrm4 Rat maneb multiple interactions ISO Srrm4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of SRRM4 mRNA CTD PMID:36117858 Srrm4 Rat methylmercury chloride increases expression ISO SRRM4 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of SRRM4 mRNA CTD PMID:28001369 Srrm4 Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] affects the methylation of SRRM4 gene CTD PMID:33148267 Srrm4 Rat paracetamol decreases expression ISO SRRM4 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of SRRM4 mRNA CTD PMID:22230336 Srrm4 Rat paraquat multiple interactions ISO Srrm4 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of SRRM4 mRNA CTD PMID:36117858 Srrm4 Rat PCB138 multiple interactions ISO Srrm4 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Srrm4 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Srrm4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SRRM4 mRNA CTD PMID:36331819 Srrm4 Rat permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] affects the methylation of SRRM4 gene CTD PMID:33148267 Srrm4 Rat potassium cyanide decreases expression ISO Srrm4 (Mus musculus) 6480464 Potassium Cyanide results in decreased expression of SRRM4 mRNA CTD PMID:33914522 Srrm4 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Srrm4 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of SRRM4 mRNA CTD PMID:28903501 Srrm4 Rat resveratrol multiple interactions ISO SRRM4 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of SRRM4 mRNA CTD PMID:23557933 Srrm4 Rat SB 431542 multiple interactions ISO SRRM4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Srrm4 Rat sodium arsenite increases expression ISO SRRM4 (Homo sapiens) 6480464 sodium arsenite results in increased expression of SRRM4 mRNA CTD PMID:29301061 Srrm4 Rat sodium arsenite decreases expression ISO Srrm4 (Mus musculus) 6480464 sodium arsenite results in decreased expression of SRRM4 mRNA CTD PMID:37682722 Srrm4 Rat sunitinib decreases expression ISO SRRM4 (Homo sapiens) 6480464 Sunitinib results in decreased expression of SRRM4 mRNA CTD PMID:31533062 Srrm4 Rat titanium dioxide decreases methylation ISO Srrm4 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of SRRM4 gene CTD PMID:35295148 Srrm4 Rat trichostatin A increases expression ISO SRRM4 (Homo sapiens) 6480464 trichostatin A results in increased expression of SRRM4 mRNA CTD PMID:26272509 Srrm4 Rat trichostatin A multiple interactions ISO SRRM4 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Srrm4 Rat triptonide increases expression ISO Srrm4 (Mus musculus) 6480464 triptonide results in increased expression of SRRM4 mRNA CTD PMID:33045310 Srrm4 Rat valproic acid affects expression ISO SRRM4 (Homo sapiens) 6480464 Valproic Acid affects the expression of SRRM4 mRNA CTD PMID:25979313 Srrm4 Rat valproic acid increases expression ISO SRRM4 (Homo sapiens) 6480464 Valproic Acid results in increased expression of SRRM4 mRNA CTD PMID:26272509 Srrm4 Rat valproic acid multiple interactions ISO SRRM4 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Srrm4 Rat vorinostat decreases expression ISO SRRM4 (Homo sapiens) 6480464 vorinostat results in decreased expression of SRRM4 mRNA CTD PMID:27188386