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Gene: Ccdc154 (coiled-coil domain containing 154) Rattus norvegicus

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Symbol:

Ccdc154

Name:

coiled-coil domain containing 154

RGD ID:

1559998

Description:

Predicted to be involved in bone mineralization involved in bone maturation. Predicted to act upstream of or within bone resorption; odontogenesis; and sensory perception of sound. Orthologous to human CCDC154 (coiled-coil domain containing 154); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 154; LOC287131; RGD1559998; similar to centrosomal protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	14,681,938 - 14,691,757 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	14,681,923 - 14,691,759 (+)	Ensembl				GRCr8
mRatBN7.2	10	14,177,271 - 14,187,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	14,177,278 - 14,187,253 (+)	Ensembl				mRatBN7.2
Rnor_6.0	10	14,518,240 - 14,529,920 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,519,164 - 14,528,277 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	14,333,873 - 14,343,771 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	14,405,553 - 14,415,281 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	13,849,873 - 13,861,554 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive osteopetrosis 1 (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cisplatin (ISO)

Dibutyl phosphate (ISO)

endosulfan (EXP)

folic acid (ISO)

GSK-J4 (ISO)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

resveratrol (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

triphenylstannane (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone mineralization involved in bone maturation (IBA,ISO)

bone remodeling (ISO)

bone resorption (ISO)

sensory perception of sound (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:20121924

Genomics

Comparative Map Data

Ccdc154
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	14,681,938 - 14,691,757 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	14,681,923 - 14,691,759 (+)	Ensembl				GRCr8
mRatBN7.2	10	14,177,271 - 14,187,378 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	14,177,278 - 14,187,253 (+)	Ensembl				mRatBN7.2
Rnor_6.0	10	14,518,240 - 14,529,920 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,519,164 - 14,528,277 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	14,333,873 - 14,343,771 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	14,405,553 - 14,415,281 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	13,849,873 - 13,861,554 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

CCDC154
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	1,434,383 - 1,444,556 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	1,434,383 - 1,444,556 (-)	Ensembl			hg38	GRCh38
GRCh37	16	1,484,384 - 1,494,557 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	1,423,396 - 1,434,858 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	1,696,988 - 1,707,090 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	1,410,857 - 1,420,959 (-)	NCBI		HuRef
CHM1_1	16	1,484,319 - 1,494,490 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	1,449,044 - 1,459,216 (-)	NCBI		T2T-CHM13v2.0

Ccdc154
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	25,381,142 - 25,390,887 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	25,381,435 - 25,390,887 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	25,162,175 - 25,171,913 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	25,162,461 - 25,171,913 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	25,299,406 - 25,308,858 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	24,890,061 - 24,899,513 (+)	NCBI		MGSCv36	mm8
MGSCv36	17	24,353,464 - 24,362,916 (+)	NCBI		MGSCv36	mm8
Celera	17	25,692,021 - 25,701,427 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.53	NCBI

Ccdc154
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,793,049 - 15,800,364 (+)	Ensembl
ChiLan1.0	NW_004955442	15,792,593 - 15,800,410 (+)	NCBI	ChiLan1.0	ChiLan1.0

CCDC154
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	1,696,340 - 1,706,659 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	5,483,690 - 5,494,011 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	54,158 - 64,522 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	1,488,751 - 1,498,392 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	1,488,750 - 1,498,293 (-)	Ensembl			panPan2	panpan1.1

CCDC154
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	39,356,234 - 39,364,053 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	39,357,273 - 39,364,740 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,624,500 - 40,632,188 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,702,775 - 39,710,470 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,704,510 - 39,710,453 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	39,379,769 - 39,390,268 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	39,352,227 - 39,359,921 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,830,637 - 39,838,332 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ccdc154
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,233,562 - 104,241,590 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	2,468,281 - 2,475,487 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	2,468,281 - 2,475,901 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC154
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	40,422,892 - 40,429,844 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	40,420,339 - 40,429,787 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	41,885,460 - 41,892,971 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC154
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	1,323,406 - 1,333,676 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	1,322,933 - 1,333,122 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666068	29,745,273 - 29,763,693 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc154
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	2,134,780 - 2,141,780 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624913	2,134,763 - 2,142,446 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ccdc154
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	2,427,025 - 2,436,337 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ccdc154
64 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	114
Count of miRNA genes:	94
Interacting mature miRNAs:	99
Transcripts:	ENSRNOT00000046884
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
631828	Alc5	Alcohol consumption QTL 5	2.4		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	10	1	17749933	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat

Markers in Region

AW538136

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,176,569 - 14,176,681 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,517,609 - 14,517,720	NCBI	Rnor6.0
Rnor_5.0	10	14,333,086 - 14,333,197	UniSTS	Rnor5.0
RGSC_v3.4	10	14,404,613 - 14,404,724	UniSTS	RGSC3.4
Celera	10	13,849,242 - 13,849,353	UniSTS
Cytogenetic Map	10	q12	UniSTS

D10Bda3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,175,704 - 14,175,812 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,516,744 - 14,516,851	NCBI	Rnor6.0
Rnor_5.0	10	14,332,221 - 14,332,328	UniSTS	Rnor5.0
RGSC_v3.4	10	14,403,748 - 14,403,855	UniSTS	RGSC3.4
Celera	10	13,848,377 - 13,848,484	UniSTS
Cytogenetic Map	10	q12	UniSTS

BI275910

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	14,186,777 - 14,186,939 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	14,527,817 - 14,527,978	NCBI	Rnor6.0
Rnor_5.0	10	14,343,294 - 14,343,455	UniSTS	Rnor5.0
RGSC_v3.4	10	14,414,821 - 14,414,982	UniSTS	RGSC3.4
Celera	10	13,859,450 - 13,859,611	UniSTS
RH 3.4 Map	10	165.4	UniSTS
Cytogenetic Map	10	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	9	30	118	66	65	34	62	34	6	232	122	8	93	57	72	31	8	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_017597601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046884 ⟹ ENSRNOP00000049506

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	14,681,963 - 14,691,756 (+)	Ensembl
mRatBN7.2 Ensembl	10	14,177,278 - 14,187,253 (+)	Ensembl
Rnor_6.0 Ensembl	10	14,519,164 - 14,528,277 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079543 ⟹ ENSRNOP00000072833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	14,519,164 - 14,528,244 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000154984 ⟹ ENSRNOP00000108645

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	14,681,923 - 14,691,759 (+)	Ensembl

RefSeq Acc Id:

XM_017597601 ⟹ XP_017453090

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	14,681,938 - 14,691,757 (+)	NCBI
mRatBN7.2	10	14,177,271 - 14,187,378 (+)	NCBI
Rnor_6.0	10	14,518,240 - 14,529,920 (+)	NCBI

Sequence:

show sequence

TGTATCCGTCTCATTTGGCTAGGACCCTTGCCTTCTGCTCTGTGTGACTCAAGCCTGTGCTGAT
TCCTGGACCACCTCTCCACCATGCCCATAACCCAGTAGCCCCAGAGCCAGAGGAGGCTTTCCAG
CAAGGGGCATGCTTCATTGTCCCCCCCCAAATCCTTCTGGGGACCAGAAGTTAGGGAGTCCACA
GGACAGGGCAGATGAGAGCTCAAGTTCCATTGGCAGTTGGCCATGAAGCCATAGGGTTCTGGTG
AGAAAAAGATTCCCAGAATAACTCAGCTGTACCTGCCTCCTCGGGATCCACTAAAGAGGCAAGG
TGGAAGGGCAGGAGCCGCTACCTCATACCTCCACTACTCTCAGGTCCACAGCCTCTCCTCCTGA
CTCATCTTCTCCCGAAGATTCAGTCTCCACTCCCTTGTCTTCTCCCCAAGATCCAGACCTTCCT
TCTTGAGCCTTACTTTCCTGAGTCCCACAGCCTTTCCTAAATCCTGGCCTCCTCTGTGGCCCAA
AGCCTTCTCTTCTCCCCTCAATGATCCCAGTTCCTGCAGCTTTCTGGCCTGGATTACTGGCTTC
TCTCCAGCCAACCACTCGGCTACCCCGGCCTGGTGTTCAGCCTTGGGTCACCATAGGGCCACTG
ACATCATTACCTGAACAACAGGTGTGGCTGCTGGTGAAACCATGTCAGAGCCAGCTGATGGCCC
CTCACTCGGGCTTTCGCCTCCACAACTGAGCACTGTCACCCTCGAGGACCTGGAGCTTCTCTTA
ACAGAAGGCCTAGCCAGTCACGAGCCCTCGAGTACCGAAAGCTTGGAGAAATATGAGTGCAGTG
GACTGGTGTCCAACTCCTTGGTCCCTGAACAGGACACCCCTAAGCAATGGAAACAGCTGGAGCA
GTGGGTAGCTGAGCTGCAGGCTGAGGTGGTTCGCCTGAGGGGACACAAGGAGCGCTGTGAGCAT
GCCACATTGGGCCTGCTTCAAGAGCTGTTGCAGGTCCATGCCCGAGTGCAGATGCAGGCCTCAG
AGCTGCGCCAGCTGAGGCAAGAGGTGCAGCAGGCAGCCTGGAGCCCAGAGAAGGAGGAACTAGA
GTTGTCTGGGCCCCAGAGCCAGGACCAGATGCAAGCCCTGGATAAAAGGCTTGTGGAGGTCCGA
GAGGCTTTGACACACATCAGGAGGAAACAGGCTCTACAGGACTCAGAGCGGAGACATGCTGAGC
AGGAGATAAACCTCAGGCTGACCAACCTGACTGCCATGCTGAGCCAAGAGGAGCAGGGCCGAGA
AGCAGCCTGCAGCGCATTGCAGAAAAACCAAGAGGACACCAGCCAGAAGGTGGACCTTGAGTCG
GCCAAGATGCAGGCCCAGATGATGAAACTCAACGAGGAGATAAGCCTCCGCTTCCTCAAGAGAG
AGGCTAAACTATGTGGTTTTCTGCAGAAGACTTTCATGGTCTTGGAGCAGAGAATGAAATCCTC
CGAGACTGCACGGCTGTCGGCAGAAAGCAGCCTGCGAGAGGAACTGGAAACCCGCTGGCAGAAG
CTGCATGAGCTGACGGAGGAGAGCTTACGGGTCTTGCGGGCACAGCGTGAGGAAGAGGAGGGTC
ACCTGCTGGAACAGTGCCGGGGCCTAGACAAAGCTGTGGTCTATCTGACCAAGTTTGTGCAACA
GAACCAGGTGTCACTGAATCGAGTCCTGATGGCTGAGCAGAAGGCCCGGGAGGCCAAGGTGAGC
TTGGAGGAGACCCAGGCTGAGGAGTTGGCTTCATATGTCCATGAGAACCTGGAGGCTGTACAGA
TGGCTGGCAAGCTAGCCCAGCAGGAAACACAGGATGCACTGGAGCTGCTCCAAGAGAAGAGCCA
GGTCCTAGAGGGGTCAGTGGCAGGGCTGGACCAGCAGCTAAAGGACCTGAGTGACCACTGTCTA
GCTCTGAGTTGGAGGCTAGATCTGCAGGAGCAAACACTAGGCCTGAAGTTGTTCCAGGCACAGG
CCGCATGGGAAGGTGTGGAGAGGGAGTCCCTGCAGGACCTGGCCCAGTGGCTGACAGAAGTCTC
AGCTCACTTGCAGGAGGTGCAGGAGAGAGTGAGCAGCCTCCCCCAGCAGATAGAAAGTGTCTCC
AACAAGTGTGTTCTTTACAAGAGTGATGTGGATGTGAAGATCTCTGCTGAGGGCAAGGCCAGGG
AGTTTGAGGTTGAGACTGTGCGACAGGAGCTGGCTGCCCTGCTGATGTCTGTGCAGCTTCTGAA
AGAGGAGAACCCTGGACGGAAGATTGCAGAGATCCAGGGCCAGCTGGCCACGTTTCAGAAGCAA
ATGATAAAGTTGGAGAACAGCCTTCAGGCCAACAAAACCATCCAGAACCTGAAGTTTAATAATG
AGACCAAGCTGCGCACAGAGGAGATTGCCACCCTGCGTGAGAGCATGCTGCATCTGTGGAGTGA
GGAGGGTCCCTGGCCTCTGACACTGGGCAGCAAGCGAGTATTCATGTCCCTGGTGAGGCAGCGG
TTCTTCATCAAGGACGTAGCCCTTGGCGAGCTGGTCCCTGTGAACTCCTGGGGAGTGTACCAAG
CTGTGAGGTGGCTTCATTGGAAGACAGTCCTCTTGAACTTGGTGACCCAGAAAAGGCCCGGAGT
GAACTCGGCAATGACCCAGTGTAGGCCTGCANTCAAGGTCACATCTCTGACTATGTTCCAGAAA
TAAACATGCCAGTTCTTGTACCTGTTGGAGTCAGAGTCTCCTGTCGTCTGCTGGGATGGCTTCT
CTACGACTCACAGGCCTGACAAGGGTGTCAAGTAGTGAGAGGGAAACCCAGAAGGCCCAAGTTA
TTAGACGTTGAAGAACCCCCTCCTTCCCCGCCTTATGCAAGGCCAGACTATCACGTCCAGTGGG
AGTTCTGTGCAGGGGCACCCAGGCCACACTTGTCAGGATACGTCCCTGCTGCTGTGAGGACAAA
TGTGAAGAATGAGGATACAGGGTCCTCAGACACCCTCAGCCCTGCACACCTACCCACTAAGTGC
TGAGGAAGCCACTTGTGAGCACGAATCAGGAGAGTGAGAATCTGTGTCTCTGTGTGATCAGGCA
GTGTCCCTCTTCTAGCCTCTCAAGAAAACCTGAACTCTGCATGCAGCTGGCCCTACAGAGACGG
AGAGGGCTGGCCTGGTTTTAGTCCAACCCAACTAGTTGCTCTTTGCCACTGACTTGAATCTTGG
GGCTAGCCTGGTAACAAAGGGCAAGGGTGTACAAGAGGTTGGTTCATAGTTCTTGCCTGAGTTC
CATTCACTTCCTGAGGACAGAGTCCTGAAGCCTGCTGTGTATAGTGGGGTCCCCGGAGAGCTGG
TAGTCAGGTGTGGCAGGTCTGGGTAAGCTTACATGCTCTGTCTCTCTCTGACTCTCTCTGTCTC
TCTCTTCTCTCTCTGTCTCTCTGTGTCTCTGTCTCTGTCTCTCTCTGTCTCCCTGTCTCTCTGT
CTTTTTCAGTGCTGGTGGCAACAGTTCCAGACACTTGGGATAAGTTCAAATCCTCTTGGGCCTG
TTCTCCTCTTGAGGGAGAGGTAACTGCATGACTACTTAGATAGACCTACTAGGTAGGGCAGGAC
CTGTGCTACAGAAGGAGGTGCTTGGTTGTTCTGAAGGTAGAAAAGGCCATTGCTGCCCCAGCAC
ACTCCTGACTCACCTACTCACTAGATCTCGGCCAGCTGTGTCCCCTCCAGAACTTGGGTGCCTC
CACTCTGCAGCTCAGAGCCACCCTCAGCAGACCAGCTGGCCAGCAGATCACTAAAATCTGGTGT
GCCCGGATGCAGTAGGCCTAGTGGGTTGGGTACAGGCTCCTTCCAGAAGGATGGAGGCAATTTT
CTTTGGGTCATGGGGGTAATGTGGCTATACTTCCGCTCCAGCCTCAGTCTTCGGCAAGCTGATA
CTCTGGGCCTAGAGAACTGCCGAAGGCCATAATCAAAGAGCTCAGCCAGGGGGCCCAGTGGTGG
CACCCTGTCTCCTCTGTGGCCCAGCCTGTGCACCTGACCCTCAGGCACCCCAGGTGAATGCATC
CTGAGCTCAGCCGCCGCCTCATCCTCTGGGGGCCCATCCTGGGCCAGGCATACCAGATCAGCAT
AGTACAGATCCCGGGCAGAACAGCTGGCTGCTTGGCTATCAGCATAGATGTCTTGGGCATCTGG
GTCTTGCCCTGTGTCCTTGCGTCCAAAGTACCGCTGAATGTCACCACTGATGAGCTCTGAGAAG
CGCAGCAGCTGCACTGGGGTCTCAGGGCTGCTGGGACCCTGAGGGACCACTCCTGAGCTCTGAG
AGTCTGGGCTGCAGCCCTGTGACCCCTCACCTTGCAGGTCTTGGTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_017453090	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM03905	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000049506
	ENSRNOP00000049506.7
	ENSRNOP00000108645.1

RefSeq Acc Id:

XP_017453090 ⟸ XM_017597601

- UniProtKB:

F1M154 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSEPADGPSLGLSPPQLSTVTLEDLELLLTEGLASHEPSSTESLEKYECSGLVSNSLVPEQDTP
KQWKQLEQWVAELQAEVVRLRGHKERCEHATLGLLQELLQVHARVQMQASELRQLRQEVQQAAW
SPEKEELELSGPQSQDQMQALDKRLVEVREALTHIRRKQALQDSERRHAEQEINLRLTNLTAML
SQEEQGREAACSALQKNQEDTSQKVDLESAKMQAQMMKLNEEISLRFLKREAKLCGFLQKTFMV
LEQRMKSSETARLSAESSLREELETRWQKLHELTEESLRVLRAQREEEEGHLLEQCRGLDKAVV
YLTKFVQQNQVSLNRVLMAEQKAREAKVSLEETQAEELASYVHENLEAVQMAGKLAQQETQDAL
ELLQEKSQVLEGSVAGLDQQLKDLSDHCLALSWRLDLQEQTLGLKLFQAQAAWEGVERESLQDL
AQWLTEVSAHLQEVQERVSSLPQQIESVSNKCVLYKSDVDVKISAEGKAREFEVETVRQELAAL
LMSVQLLKEENPGRKIAEIQGQLATFQKQMIKLENSLQANKTIQNLKFNNETKLRTEEIATLRE
SMLHLWSEEGPWPLTLGSKRVFMSLVRQRFFIKDVALGELVPVNSWGVYQAVRWLHWKTVLLNL
VTQKRPGVNSAMTQCRPAXKVTSLTMFQK

hide sequence

Ensembl Acc Id:

ENSRNOP00000072833 ⟸ ENSRNOT00000079543

Ensembl Acc Id:

ENSRNOP00000049506 ⟸ ENSRNOT00000046884

Ensembl Acc Id:

ENSRNOP00000108645 ⟸ ENSRNOT00000154984

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M154-F1-model_v2	AlphaFold	F1M154	1-668	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559998	AgrOrtholog
BioCyc Gene	G2FUF-25804	BioCyc
Ensembl Genes	ENSRNOG00000030541	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000046884	ENTREZGENE
	ENSRNOT00000046884.7	UniProtKB/TrEMBL
	ENSRNOT00000154984.1	UniProtKB/TrEMBL
InterPro	CCDC154	UniProtKB/TrEMBL
NCBI Gene	287131	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 154	UniProtKB/TrEMBL
	PTHR35153	UniProtKB/TrEMBL
Pfam	DUF4631	UniProtKB/TrEMBL
PhenoGen	Ccdc154	PhenoGen
RatGTEx	ENSRNOG00000030541	RatGTEx
UniProt	A0ABK0LD22_RAT	UniProtKB/TrEMBL
	F1M154	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-09	Ccdc154	coiled-coil domain containing 154	RGD1559998	similar to centrosomal protein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1559998	similar to centrosomal protein 2	RGD1559998_predicted	similar to centrosomal protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1559998_predicted	similar to centrosomal protein 2 (predicted)	LOC287131	similar to centrosomal protein 2	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC287131	similar to centrosomal protein 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI