Srsf11 (serine and arginine rich splicing factor 11) - Rat Genome Database

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Gene: Srsf11 (serine and arginine rich splicing factor 11) Rattus norvegicus
Analyze
Symbol: Srsf11
Name: serine and arginine rich splicing factor 11
RGD ID: 1559953
Description: Predicted to enable RNA binding activity and identical protein binding activity. Predicted to be involved in RNA splicing. Predicted to be active in nucleoplasm. Orthologous to human SRSF11 (serine and arginine rich splicing factor 11); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC502603; MGC116323; serine/arginine-rich splicing factor 11; Sfrs11; similar to splicing factor p54; splicing factor, arginine/serine-rich 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82249,733,464 - 249,760,296 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2249,733,464 - 249,760,499 (-)EnsemblGRCr8
mRatBN7.22247,074,623 - 247,101,460 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2247,074,631 - 247,101,425 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2254,807,001 - 254,833,911 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02252,700,498 - 252,727,286 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02247,669,178 - 247,695,956 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02264,837,463 - 264,864,296 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)Ensemblrn6Rnor6.0
Rnor_5.02283,477,393 - 283,504,112 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42256,154,645 - 256,175,169 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2238,874,964 - 238,894,383 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
auramine O  (ISO)
Benzo[ghi]perylene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dimethylarsinous acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
Evodiamine  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
flusilazole  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
graphene oxide  (ISO)
hexaconazole  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
menadione  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
miconazole  (ISO)
mono(2-ethyl-5-oxohexyl) phthalate  (ISO)
nefazodone  (EXP)
Nutlin-3  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pinosylvin  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tetraphene  (ISO)
titanium dioxide  (ISO)
trans-pinosylvin  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders. Stamova BS, etal., Mol Autism. 2013 Sep 4;4(1):30. doi: 10.1186/2040-2392-4-30.
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Discovering transcription and splicing networks in myelodysplastic syndromes. Wang H, etal., PLoS One. 2013 Nov 14;8(11):e79118. doi: 10.1371/journal.pone.0079118. eCollection 2013.
Additional References at PubMed
PMID:22658674   PMID:22681889   PMID:31505169  


Genomics

Comparative Map Data
Srsf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82249,733,464 - 249,760,296 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2249,733,464 - 249,760,499 (-)EnsemblGRCr8
mRatBN7.22247,074,623 - 247,101,460 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2247,074,631 - 247,101,425 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2254,807,001 - 254,833,911 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02252,700,498 - 252,727,286 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02247,669,178 - 247,695,956 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02264,837,463 - 264,864,296 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)Ensemblrn6Rnor6.0
Rnor_5.02283,477,393 - 283,504,112 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42256,154,645 - 256,175,169 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2238,874,964 - 238,894,383 (-)NCBICelera
Cytogenetic Map2q45NCBI
SRSF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38170,205,696 - 70,253,052 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl170,205,670 - 70,253,052 (+)Ensemblhg38GRCh38
GRCh37170,671,379 - 70,718,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36170,443,953 - 70,490,272 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34170,383,385 - 70,429,705NCBI
Celera168,961,312 - 69,007,634 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef168,782,549 - 68,828,871 (+)NCBIHuRef
CHM1_1170,786,765 - 70,833,100 (+)NCBICHM1_1
T2T-CHM13v2.0170,084,212 - 70,131,570 (+)NCBIT2T-CHM13v2.0
Srsf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,716,552 - 157,742,304 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3157,716,110 - 157,742,276 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383158,010,915 - 158,036,667 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3158,010,473 - 158,036,639 (-)Ensemblmm10GRCm38
MGSCv373157,673,457 - 157,699,603 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363157,945,937 - 157,958,504 (-)NCBIMGSCv36mm8
Celera3164,477,852 - 164,503,994 (-)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.63NCBI
Srsf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542321,669,471 - 21,706,327 (-)Ensembl
ChiLan1.0NW_00495542321,669,925 - 21,706,260 (-)NCBIChiLan1.0ChiLan1.0
SRSF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21156,621,871 - 156,668,201 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11155,780,985 - 155,827,282 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0169,441,043 - 69,488,427 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1171,426,668 - 71,472,580 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl171,442,600 - 71,471,361 (+)EnsemblpanPan2panpan1.1
SRSF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1675,473,794 - 75,495,860 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl675,464,957 - 75,492,103 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha678,087,040 - 78,115,284 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0676,066,201 - 76,094,670 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl676,066,748 - 76,108,650 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1675,619,024 - 75,647,269 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0675,514,315 - 75,542,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0676,015,682 - 76,043,946 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Srsf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505882,663,665 - 82,699,146 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365911,789,366 - 1,816,342 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365911,789,358 - 1,825,854 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6142,621,924 - 142,642,073 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16142,621,904 - 142,668,107 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26132,193,667 - 132,240,416 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRSF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12062,885,980 - 62,932,394 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2062,883,026 - 62,916,436 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603354,689,579 - 54,736,573 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srsf11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474225,761,410 - 25,789,972 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474225,761,410 - 25,787,195 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Srsf11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v133,550,304 - 3,577,157 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:180
Count of miRNA genes:132
Interacting mature miRNAs:155
Transcripts:ENSRNOT00000044236
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2214404877251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2214404877251712708Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2214404877251712708Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2218051934251712708Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2214404877251712708Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2220274283249795005Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2214404877251712708Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat

Markers in Region
WI-18827  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22247,075,352 - 247,075,474 (+)MAPPERmRatBN7.2
Rnor_6.02264,838,193 - 264,838,314NCBIRnor6.0
Rnor_5.02283,478,119 - 283,478,240UniSTSRnor5.0
RGSC_v3.42256,155,371 - 256,155,492UniSTSRGSC3.4
Celera2238,875,690 - 238,875,811UniSTS
Cytogenetic Map2q45UniSTS
RH143041  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22247,091,682 - 247,091,917 (+)MAPPERmRatBN7.2
Rnor_6.02264,854,522 - 264,854,756NCBIRnor6.0
Rnor_5.02283,494,360 - 283,494,594UniSTSRnor5.0
RGSC_v3.42256,172,684 - 256,172,918UniSTSRGSC3.4
Celera2238,891,898 - 238,892,132UniSTS
RH 3.4 Map21646.11UniSTS
Cytogenetic Map2q45UniSTS
UniSTS:225095  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22247,074,673 - 247,074,777 (+)MAPPERmRatBN7.2
Rnor_6.02264,837,514 - 264,837,617NCBIRnor6.0
Rnor_5.02283,477,440 - 283,477,543UniSTSRnor5.0
RGSC_v3.42256,154,692 - 256,154,795UniSTSRGSC3.4
Celera2238,875,011 - 238,875,114UniSTS
Cytogenetic Map2q45UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000044236   ⟹   ENSRNOP00000043202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2249,733,464 - 249,760,285 (-)Ensembl
mRatBN7.2 Ensembl2247,074,631 - 247,101,425 (-)Ensembl
Rnor_6.0 Ensembl2264,837,472 - 264,864,265 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000127924   ⟹   ENSRNOP00000101625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2249,733,464 - 249,760,499 (-)Ensembl
RefSeq Acc Id: NM_001399822   ⟹   NP_001386751
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,760,258 (-)NCBI
mRatBN7.22247,074,627 - 247,101,422 (-)NCBI
RefSeq Acc Id: XM_006233540   ⟹   XP_006233602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,760,296 (-)NCBI
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233542   ⟹   XP_006233604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,760,296 (-)NCBI
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233543   ⟹   XP_006233605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,755,592 (-)NCBI
mRatBN7.22247,074,623 - 247,101,353 (-)NCBI
Rnor_6.02264,837,463 - 264,864,258 (-)NCBI
Rnor_5.02283,477,393 - 283,504,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761567   ⟹   XP_008759789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,760,296 (-)NCBI
mRatBN7.22247,074,623 - 247,101,460 (-)NCBI
Rnor_6.02264,837,463 - 264,864,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761569   ⟹   XP_008759791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,760,258 (-)NCBI
mRatBN7.22247,074,623 - 247,101,354 (-)NCBI
Rnor_6.02264,837,463 - 264,864,258 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102967   ⟹   XP_038958895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,733,464 - 249,748,733 (-)NCBI
mRatBN7.22247,074,623 - 247,089,896 (-)NCBI
RefSeq Acc Id: XM_063282413   ⟹   XP_063138483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82249,738,218 - 249,760,296 (-)NCBI
RefSeq Acc Id: XP_006233604   ⟸   XM_006233542
- Peptide Label: isoform X3
- UniProtKB: D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233602   ⟸   XM_006233540
- Peptide Label: isoform X1
- UniProtKB: A0A0G2QC38 (UniProtKB/TrEMBL),   D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233605   ⟸   XM_006233543
- Peptide Label: isoform X4
- UniProtKB: D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759789   ⟸   XM_008761567
- Peptide Label: isoform X2
- UniProtKB: D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759791   ⟸   XM_008761569
- Peptide Label: isoform X5
- UniProtKB: D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000043202   ⟸   ENSRNOT00000044236
RefSeq Acc Id: XP_038958895   ⟸   XM_039102967
- Peptide Label: isoform X7
- UniProtKB: A6HWT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386751   ⟸   NM_001399822
- UniProtKB: A6HWT5 (UniProtKB/TrEMBL),   D3ZBT0 (UniProtKB/TrEMBL),   Q4KLK1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138483   ⟸   XM_063282413
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000101625   ⟸   ENSRNOT00000127924
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2QC38-F1-model_v2 AlphaFold A0A0G2QC38 1-511 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691843
Promoter ID:EPDNEW_R2367
Type:initiation region
Name:Srsf11_1
Description:serine and arginine rich splicing factor 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02264,864,261 - 264,864,321EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559953 AgrOrtholog
BioCyc Gene G2FUF-50705 BioCyc
Ensembl Genes ENSRNOG00000029592 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044236 ENTREZGENE
  ENSRNOT00000044236.7 UniProtKB/TrEMBL
  ENSRNOT00000127924 ENTREZGENE
  ENSRNOT00000127924.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381485 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SRSF11 UniProtKB/TrEMBL
MGC_CLONE MGC:116323 IMAGE-MGC_LOAD
NCBI Gene 502603 ENTREZGENE
PANTHER PTHR32343:SF6 UniProtKB/TrEMBL
  SERINE/ARGININE-RICH SPLICING FACTOR UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Srsf11 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029592 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A0G2QC38 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LAC0_RAT UniProtKB/TrEMBL
  A6HWT5 ENTREZGENE, UniProtKB/TrEMBL
  A6HWT7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBT0 ENTREZGENE
  Q4KLK1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3ZBT0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Srsf11  serine and arginine rich splicing factor 11  Srsf11  serine/arginine-rich splicing factor 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Srsf11  serine/arginine-rich splicing factor 11  Sfrs11  splicing factor, arginine/serine-rich 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Sfrs11  splicing factor, arginine/serine-rich 11  LOC502603  similar to splicing factor p54  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC502603  similar to splicing factor p54      Symbol and Name status set to provisional 70820 PROVISIONAL