Pex1 (peroxisomal biogenesis factor 1) - Rat Genome Database

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Gene: Pex1 (peroxisomal biogenesis factor 1) Rattus norvegicus
Analyze
Symbol: Pex1
Name: peroxisomal biogenesis factor 1
RGD ID: 1559939
Description: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ubiquitin-dependent protein binding activity. Predicted to be involved in protein import into peroxisome matrix, receptor recycling; protein targeting to peroxisome; and protein unfolding. Predicted to act upstream of or within microtubule-based peroxisome localization. Located in peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Orthologous to human PEX1 (peroxisomal biogenesis factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC500006; peroxisomal ATPase PEX1; peroxisome biogenesis factor 1; RGD1559939; similar to peroxisome biogenesis factor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8431,474,670 - 31,513,621 (-)NCBIGRCr8
mRatBN7.2430,519,950 - 30,558,953 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl430,519,955 - 30,558,921 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx435,492,702 - 35,531,639 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0431,418,781 - 31,457,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0429,814,810 - 29,853,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0427,659,376 - 27,698,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl427,659,381 - 27,698,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0427,562,602 - 27,601,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,235,147 - 27,275,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera425,944,627 - 25,983,247 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,ISO)
peroxisomal membrane  (IBA,IDA,ISO)
peroxisome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder. Berendse K, etal., Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2774-2787. doi: 10.1016/j.bbadis.2019.06.013. Epub 2019 Jun 15.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The Pex1-G844D mouse: a model for mild human Zellweger spectrum disorder. Hiebler S, etal., Mol Genet Metab. 2014 Apr;111(4):522-532. doi: 10.1016/j.ymgme.2014.01.008. Epub 2014 Jan 23.
4. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9398847   PMID:9588209   PMID:11439091   PMID:16449325   PMID:16854980   PMID:18570454   PMID:21525035   PMID:21980954   PMID:27826738  


Genomics

Comparative Map Data
Pex1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8431,474,670 - 31,513,621 (-)NCBIGRCr8
mRatBN7.2430,519,950 - 30,558,953 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl430,519,955 - 30,558,921 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx435,492,702 - 35,531,639 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0431,418,781 - 31,457,718 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0429,814,810 - 29,853,743 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0427,659,376 - 27,698,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl427,659,381 - 27,698,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0427,562,602 - 27,601,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,235,147 - 27,275,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera425,944,627 - 25,983,247 (-)NCBICelera
Cytogenetic Map4q13NCBI
PEX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38792,487,025 - 92,528,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl792,487,020 - 92,528,520 (-)EnsemblGRCh38hg38GRCh38
GRCh37792,116,339 - 92,157,834 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36791,954,273 - 91,995,781 (-)NCBINCBI36Build 36hg18NCBI36
Build 34791,760,990 - 91,802,460NCBI
Celera786,820,874 - 86,862,377 (-)NCBICelera
Cytogenetic Map7q21.2NCBI
HuRef786,725,109 - 86,766,599 (-)NCBIHuRef
CHM1_1792,046,373 - 92,087,866 (-)NCBICHM1_1
T2T-CHM13v2.0793,728,340 - 93,769,797 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2791,445,547 - 91,487,069 (-)NCBI
Pex1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3953,646,066 - 3,687,230 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl53,646,066 - 3,687,232 (+)EnsemblGRCm39 Ensembl
GRCm3853,596,066 - 3,637,230 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl53,596,066 - 3,637,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv3753,596,066 - 3,637,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3653,602,072 - 3,643,107 (+)NCBIMGSCv36mm8
Celera53,532,126 - 3,572,649 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.26NCBI
Pex1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554329,418,678 - 9,461,419 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554329,418,480 - 9,461,507 (-)NCBIChiLan1.0ChiLan1.0
PEX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26110,372,447 - 110,413,736 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17158,635,150 - 158,678,317 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0784,484,965 - 84,526,309 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1798,081,018 - 98,122,335 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl798,081,021 - 98,122,335 (-)Ensemblpanpan1.1panPan2
PEX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11418,073,759 - 18,144,489 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1418,073,758 - 18,143,152 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1417,634,623 - 17,705,370 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01417,880,526 - 17,951,301 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1417,880,343 - 17,922,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11418,041,002 - 18,111,759 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01417,753,220 - 17,823,831 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01418,027,289 - 18,098,075 (-)NCBIUU_Cfam_GSD_1.0
Pex1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511831,459,732 - 31,507,925 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368031,291,702 - 1,340,178 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368031,291,867 - 1,340,123 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PEX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl972,385,475 - 72,444,582 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1972,385,755 - 72,444,718 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2979,114,205 - 79,173,283 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PEX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12156,493,424 - 56,535,565 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2156,493,435 - 56,535,154 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604247,744,820 - 47,787,087 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pex1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624809668,345 - 712,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624809668,248 - 713,036 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pex1
130 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:40
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000038136
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat

Markers in Region
AI555451  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2430,521,895 - 30,522,341 (+)MAPPERmRatBN7.2
Rnor_6.0427,661,322 - 27,661,767NCBIRnor6.0
Rnor_5.0427,564,548 - 27,564,993UniSTSRnor5.0
RGSC_v3.4427,237,088 - 27,237,533UniSTSRGSC3.4
Celera425,946,568 - 25,947,013UniSTS
RH 3.4 Map4168.9UniSTS
Cytogenetic Map4q13UniSTS
RH134880  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2430,520,050 - 30,520,251 (+)MAPPERmRatBN7.2
Rnor_6.0427,659,477 - 27,659,677NCBIRnor6.0
Rnor_5.0427,562,703 - 27,562,903UniSTSRnor5.0
RGSC_v3.4427,235,243 - 27,235,443UniSTSRGSC3.4
Celera425,944,723 - 25,944,923UniSTS
RH 3.4 Map4169.29UniSTS
Cytogenetic Map4q13UniSTS
RH129188  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2430,519,674 - 30,519,870 (+)MAPPERmRatBN7.2
Rnor_6.0427,659,101 - 27,659,296NCBIRnor6.0
Rnor_5.0427,562,327 - 27,562,522UniSTSRnor5.0
RGSC_v3.4427,234,867 - 27,235,062UniSTSRGSC3.4
Celera425,944,347 - 25,944,542UniSTS
RH 3.4 Map4169.2UniSTS
Cytogenetic Map4q13UniSTS
RH131152  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2430,547,446 - 30,547,630 (+)MAPPERmRatBN7.2
Rnor_6.0427,686,610 - 27,686,793NCBIRnor6.0
Rnor_5.0427,589,843 - 27,590,026UniSTSRnor5.0
RGSC_v3.4427,263,545 - 27,263,728UniSTSRGSC3.4
Celera425,971,798 - 25,971,981UniSTS
Cytogenetic Map4q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 20 45 29 14 29 74 35 39 11
Low 1 23 12 12 5 12 8 11 2 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000038136   ⟹   ENSRNOP00000032605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl430,520,392 - 30,558,921 (-)Ensembl
Rnor_6.0 Ensembl427,659,381 - 27,698,037 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094008   ⟹   ENSRNOP00000090555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl430,520,392 - 30,558,921 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104070   ⟹   ENSRNOP00000093891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl430,519,955 - 30,549,442 (-)Ensembl
RefSeq Acc Id: NM_001109220   ⟹   NP_001102690
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8431,474,675 - 31,513,612 (-)NCBI
mRatBN7.2430,519,955 - 30,558,898 (-)NCBI
Rnor_6.0427,659,381 - 27,698,037 (-)NCBI
Rnor_5.0427,562,602 - 27,601,351 (-)NCBI
RGSC_v3.4427,235,147 - 27,275,076 (-)RGD
Celera425,944,627 - 25,983,247 (-)RGD
Sequence:
RefSeq Acc Id: XM_006236054   ⟹   XP_006236116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8431,474,670 - 31,513,621 (-)NCBI
mRatBN7.2430,519,950 - 30,558,906 (-)NCBI
Rnor_6.0427,659,376 - 27,697,996 (-)NCBI
Rnor_5.0427,562,602 - 27,601,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108094   ⟹   XP_038964022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8431,474,670 - 31,499,171 (-)NCBI
mRatBN7.2430,519,950 - 30,544,452 (-)NCBI
RefSeq Acc Id: XM_039108095   ⟹   XP_038964023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8431,487,667 - 31,513,618 (-)NCBI
mRatBN7.2430,532,942 - 30,558,953 (-)NCBI
RefSeq Acc Id: XR_005503290
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8431,480,756 - 31,513,618 (-)NCBI
mRatBN7.2430,525,920 - 30,558,953 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102690   ⟸   NM_001109220
- UniProtKB: D3ZZB2 (UniProtKB/TrEMBL),   A6K285 (UniProtKB/TrEMBL),   A0A8I6ADS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236116   ⟸   XM_006236054
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032605   ⟸   ENSRNOT00000038136
RefSeq Acc Id: XP_038964022   ⟸   XM_039108094
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038964023   ⟸   XM_039108095
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000090555   ⟸   ENSRNOT00000094008
RefSeq Acc Id: ENSRNOP00000093891   ⟸   ENSRNOT00000104070
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZB2-F1-model_v2 AlphaFold D3ZZB2 1-1283 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692847
Promoter ID:EPDNEW_R3372
Type:initiation region
Name:Pex1_1
Description:peroxisomal biogenesis factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0427,698,038 - 27,698,098EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559939 AgrOrtholog
BioCyc Gene G2FUF-45763 BioCyc
Ensembl Genes ENSRNOG00000025991 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038136 ENTREZGENE
  ENSRNOT00000038136.4 UniProtKB/TrEMBL
  ENSRNOT00000094008.1 UniProtKB/TrEMBL
  ENSRNOT00000104070.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  2.40.40.20 UniProtKB/TrEMBL
  3.10.330.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA_lid_3 UniProtKB/TrEMBL
  Asp_de-COase-like_fold UniProtKB/TrEMBL
  ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  CDC48_domain_2-like UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Peroxisome_synth_fac_1_a/b UniProtKB/TrEMBL
  PEX-1N UniProtKB/TrEMBL
KEGG Report rno:500006 UniProtKB/TrEMBL
NCBI Gene 500006 ENTREZGENE
PANTHER AAA-FAMILY ATPASE UniProtKB/TrEMBL
  PTHR23077:SF12 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  PEX-1N UniProtKB/TrEMBL
  PEX-2N UniProtKB/TrEMBL
PhenoGen Pex1 PhenoGen
PROSITE AAA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025991 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP Asp_decarb_fold UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF54585 UniProtKB/TrEMBL
UniProt A0A8I6ADS4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALA5 ENTREZGENE, UniProtKB/TrEMBL
  A6K285 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZB2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Pex1  peroxisomal biogenesis factor 1  Pex1  peroxisome biogenesis factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Pex1  peroxisome biogenesis factor 1  Pex1  peroxisomal biogenesis factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-03 Pex1  peroxisomal biogenesis factor 1  Pex1  peroxisome biogenesis factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-28 Pex1  peroxisome biogenesis factor 1  RGD1559939_predicted  similar to peroxisome biogenesis factor 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1559939_predicted  similar to peroxisome biogenesis factor 1 (predicted)  LOC500006  similar to peroxisome biogenesis factor 1  Symbol and Name status set to approved 1299863 APPROVED