Slc25a43 (solute carrier family 25, member 43) - Rat Genome Database

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Gene: Slc25a43 (solute carrier family 25, member 43) Rattus norvegicus
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Symbol: Slc25a43
Name: solute carrier family 25, member 43
RGD ID: 1559928
Description: Predicted to be involved in transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to human SLC25A43 (solute carrier family 25 member 43); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC298318; RGD1559928; similar to mitochondrial solute carrier protein; solute carrier family 25 member 43
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,843,181 - 120,877,515 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX120,843,243 - 120,877,515 (+)EnsemblGRCr8
mRatBN7.2X115,977,437 - 116,011,789 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX115,977,510 - 116,011,205 (+)EnsemblmRatBN7.2
Rnor_6.0X123,349,836 - 123,384,798 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,350,346 - 123,384,846 (+)Ensemblrn6Rnor6.0
Rnor_5.0X123,495,546 - 123,529,964 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X8,096,134 - 8,129,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX115,207,320 - 115,241,851 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18614015  


Genomics

Comparative Map Data
Slc25a43
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,843,181 - 120,877,515 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX120,843,243 - 120,877,515 (+)EnsemblGRCr8
mRatBN7.2X115,977,437 - 116,011,789 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX115,977,510 - 116,011,205 (+)EnsemblmRatBN7.2
Rnor_6.0X123,349,836 - 123,384,798 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,350,346 - 123,384,846 (+)Ensemblrn6Rnor6.0
Rnor_5.0X123,495,546 - 123,529,964 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X8,096,134 - 8,129,172 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX115,207,320 - 115,241,851 (+)NCBICelera
Cytogenetic MapXq34NCBI
SLC25A43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X119,399,336 - 119,454,478 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX119,399,336 - 119,454,478 (+)Ensemblhg38GRCh38
GRCh37X118,533,299 - 118,588,441 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,417,051 - 118,472,462 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX118,987,995 - 119,043,163 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX108,026,280 - 108,081,595 (+)NCBIHuRef
CHM1_1X118,444,484 - 118,499,613 (+)NCBICHM1_1
T2T-CHM13v2.0X117,777,069 - 117,832,189 (+)NCBIT2T-CHM13v2.0
Slc25a43
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X36,007,223 - 36,040,960 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX36,007,312 - 36,040,855 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X36,743,570 - 36,777,307 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX36,743,659 - 36,777,202 (+)Ensemblmm10GRCm38
MGSCv37X34,283,654 - 34,317,197 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X33,175,104 - 33,208,667 (+)NCBIMGSCv36mm8
CeleraX23,467,500 - 23,501,050 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX21.15NCBI
Slc25a43
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955534510,898 - 548,047 (-)Ensembl
ChiLan1.0NW_004955534513,757 - 548,027 (-)NCBIChiLan1.0ChiLan1.0
SLC25A43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X118,783,908 - 118,833,815 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X118,787,584 - 118,838,056 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X108,435,500 - 108,485,383 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X118,861,673 - 118,910,892 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX118,861,673 - 118,910,892 (+)EnsemblpanPan2panpan1.1
SLC25A43
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X91,471,700 - 91,511,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX91,471,642 - 91,509,790 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX77,548,122 - 77,586,215 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X93,212,826 - 93,250,836 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX93,212,102 - 93,249,250 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X90,665,636 - 90,703,655 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X92,424,339 - 92,462,345 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X92,153,245 - 92,191,350 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc25a43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X90,488,242 - 90,531,863 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647910,453,187 - 10,499,251 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647910,455,632 - 10,499,224 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A43
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX97,868,696 - 97,906,760 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X97,868,804 - 97,906,771 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,758,765 - 113,796,853 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606532,147,116 - 32,195,759 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a43
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248953,428,522 - 3,459,848 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248953,428,439 - 3,460,829 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc25a43
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X102,917,811 - 102,951,482 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc25a43
184 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:41
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000017026
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 157 91 90 59 90 59 6 354 190 11 135 81 92 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000017026   ⟹   ENSRNOP00000017026
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX120,843,243 - 120,877,515 (+)Ensembl
mRatBN7.2 EnsemblX115,977,510 - 116,011,205 (+)Ensembl
Rnor_6.0 EnsemblX123,350,346 - 123,384,846 (+)Ensembl
RefSeq Acc Id: XM_003752132   ⟹   XP_003752180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,843,181 - 120,877,515 (+)NCBI
mRatBN7.2X115,977,447 - 116,011,789 (+)NCBI
Rnor_6.0X123,349,836 - 123,384,798 (+)NCBI
Rnor_5.0X123,495,546 - 123,529,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100201   ⟹   XP_038956129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,843,205 - 120,855,466 (+)NCBI
mRatBN7.2X115,977,437 - 115,989,736 (+)NCBI
RefSeq Acc Id: XM_063280362   ⟹   XP_063136432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,843,206 - 120,866,713 (+)NCBI
RefSeq Acc Id: XR_005498125
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,843,206 - 120,874,997 (+)NCBI
mRatBN7.2X115,977,442 - 116,009,272 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001419807 (Get FASTA)   NCBI Sequence Viewer  
  XP_003752180 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956129 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136432 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017026
  ENSRNOP00000017026.5
RefSeq Acc Id: XP_003752180   ⟸   XM_003752132
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000017026   ⟸   ENSRNOT00000017026
RefSeq Acc Id: XP_038956129   ⟸   XM_039100201
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063136432   ⟸   XM_063280362
- Peptide Label: isoform X2
- UniProtKB: A6JMF7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZG94-F1-model_v2 AlphaFold D3ZG94 1-329 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701986
Promoter ID:EPDNEW_R12505
Type:single initiation site
Name:Slc25a43_1
Description:solute carrier family 25, member 43
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X123,350,335 - 123,350,395EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559928 AgrOrtholog
BioCyc Gene G2FUF-1312 BioCyc
Ensembl Genes ENSRNOG00000012756 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017026 ENTREZGENE
  ENSRNOT00000017026.8 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mit_carrier UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom UniProtKB/TrEMBL
KEGG Report rno:298318 UniProtKB/TrEMBL
NCBI Gene 298318 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 25 UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PhenoGen Slc25a43 PhenoGen
PRINTS MITOCARRIER UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012756 RatGTEx
Superfamily-SCOP Mitoch_carrier UniProtKB/TrEMBL
UniProt A6JMF7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZG94 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-22 Slc25a43  solute carrier family 25, member 43  RGD1559928  similar to mitochondrial solute carrier protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559928  similar to mitochondrial solute carrier protein   RGD1559928_predicted  similar to mitochondrial solute carrier protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559928_predicted  similar to mitochondrial solute carrier protein (predicted)  LOC298318  similar to mitochondrial solute carrier protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC298318  similar to mitochondrial solute carrier protein      Symbol and Name status set to provisional 70820 PROVISIONAL