Cntnap5a (contactin associated protein-like 5A) - Rat Genome Database

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Gene: Cntnap5a (contactin associated protein-like 5A) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Cntnap5a
Name: contactin associated protein-like 5A
RGD ID: 1559812
Description: Predicted to be involved in cell adhesion. Predicted to be located in cell junction and membrane. Orthologous to human CNTNAP5 (contactin associated protein family member 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Caspr5-1; cell recognition molecule Caspr5-1; cell recognition molecule Caspr5a; contactin associated protein-like 5-1; contactin-associated protein like 5-1; contactin-associated protein like 5-1-like; contactin-associated protein-like 5a; LOC100910512; LOC297832; RGD1559812; similar to contactin associated protein-like 5 isoform 1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8138,968,048 - 9,976,147 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl138,968,423 - 9,970,372 (+)EnsemblGRCr8
mRatBN7.2138,960,951 - 9,962,906 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl138,961,119 - 9,962,584 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx138,978,049 - 9,958,963 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01310,287,410 - 11,268,354 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0138,957,568 - 9,938,560 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01379,860 - 841,474 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01317,496,156 - 18,057,247 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01311,781,251 - 11,886,991 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41328,709,670 - 29,730,378 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera139,876,687 - 10,367,262 (+)NCBICelera
Cytogenetic Map13p13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16845472  


Genomics

Variants

.
Variants in Cntnap5a
6633 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:68
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000050329
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134785618Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13600200837088115Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13143736554Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)13308875548088755Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13600200847359539Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13134785618Rat

Markers in Region
D6Got193  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2139,536,837 - 9,537,052 (+)MAPPERmRatBN7.2
Rnor_6.01312,826,001 - 12,826,215NCBIRnor6.0
Rnor_5.01318,064,724 - 18,064,938UniSTSRnor5.0
RGSC_v3.41329,297,622 - 29,297,837RGDRGSC3.4
RGSC_v3.41329,297,623 - 29,297,837UniSTSRGSC3.4
RGSC_v3.11329,300,446 - 29,300,661RGD
Cytogenetic Map13p11UniSTS
D13Wox1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.41328,821,098 - 28,821,258UniSTSRGSC3.4
RGSC_v3.41328,898,053 - 28,898,225UniSTSRGSC3.4
RGSC_v3.11328,900,876 - 28,901,049RGD
Cytogenetic Map13 RGD
D13Mco17  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8139,325,140 - 9,325,360 (+)Marker Load Pipeline
mRatBN7.2139,318,024 - 9,318,244 (+)MAPPERmRatBN7.2
Rnor_6.01312,617,139 - 12,617,358NCBIRnor6.0
Rnor_5.01317,854,801 - 17,855,020UniSTSRnor5.0
RGSC_v3.41329,074,573 - 29,074,793RGDRGSC3.4
RGSC_v3.41329,074,574 - 29,074,793UniSTSRGSC3.4
Celera1310,231,384 - 10,231,603UniSTS
RGSC_v3.11329,077,397 - 29,077,617RGD
Cytogenetic Map13p11UniSTS
D13Got206  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.013721,687 - 721,915NCBIRnor5.0
Rnor_5.01311,811,041 - 11,811,269NCBIRnor5.0
Rnor_5.013810,522 - 810,750NCBIRnor5.0
RGSC_v3.41329,638,367 - 29,638,594UniSTSRGSC3.4
Cytogenetic Map13p11UniSTS
D13Got208  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2139,081,442 - 9,081,696 (+)MAPPERmRatBN7.2
Rnor_6.01312,373,743 - 12,373,998NCBIRnor6.0
Rnor_5.01317,613,680 - 17,613,935UniSTSRnor5.0
RGSC_v3.41328,830,710 - 28,830,965UniSTSRGSC3.4
Celera139,996,700 - 9,996,987UniSTS
Cytogenetic Map13p11UniSTS
D13Got250  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.013687,412 - 687,561NCBIRnor5.0
Rnor_5.01311,846,052 - 11,846,201NCBIRnor5.0
Rnor_5.013371,719 - 371,868NCBIRnor5.0
RGSC_v3.41329,603,732 - 29,603,880UniSTSRGSC3.4
Cytogenetic Map13p11UniSTS
AU046813  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2139,127,213 - 9,127,701 (+)MAPPERmRatBN7.2
mRatBN7.2139,127,517 - 9,127,701 (+)MAPPERmRatBN7.2
Rnor_6.01312,419,956 - 12,420,528NCBIRnor6.0
Rnor_6.01312,420,345 - 12,420,528NCBIRnor6.0
Rnor_5.01317,660,282 - 17,660,465UniSTSRnor5.0
Rnor_5.01317,659,893 - 17,660,465UniSTSRnor5.0
RGSC_v3.41328,876,786 - 28,876,969UniSTSRGSC3.4
Celera1310,042,794 - 10,042,977UniSTS
Cytogenetic Map13p11UniSTS
D13Wox1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01312,364,396 - 12,364,557NCBIRnor6.0
Rnor_5.01317,604,333 - 17,604,494UniSTSRnor5.0
RGSC_v3.41328,898,053 - 28,898,225UniSTSRGSC3.4
RGSC_v3.41328,821,098 - 28,821,258UniSTSRGSC3.4
Cytogenetic Map13p11UniSTS


Expression

RNA-SEQ Expression

circulatory system
ectoderm
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
7 11 24 7 12 17 2 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000067198   ⟹   ENSRNOP00000062287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl138,968,423 - 9,969,994 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092965   ⟹   ENSRNOP00000076029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl139,209,146 - 9,969,994 (+)Ensembl
mRatBN7.2 Ensembl139,202,035 - 9,962,584 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104126   ⟹   ENSRNOP00000087083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl138,968,423 - 9,969,994 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107476   ⟹   ENSRNOP00000088891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl139,208,557 - 9,969,994 (+)Ensembl
mRatBN7.2 Ensembl139,201,446 - 9,962,584 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111316   ⟹   ENSRNOP00000095092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl138,968,423 - 9,969,994 (+)Ensembl
mRatBN7.2 Ensembl138,961,119 - 9,962,584 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112687   ⟹   ENSRNOP00000088436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl138,968,423 - 9,970,372 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118535   ⟹   ENSRNOP00000080529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl139,208,969 - 9,969,994 (+)Ensembl
mRatBN7.2 Ensembl139,201,858 - 9,962,584 (+)Ensembl
RefSeq Acc Id: NM_001047865   ⟹   NP_001041330
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8138,968,230 - 9,969,994 (+)NCBI
mRatBN7.2138,961,114 - 9,962,906 (+)NCBI
Rnor_6.01379,860 - 841,474 (+)NCBI
Rnor_5.01311,781,251 - 11,886,991 (-)NCBI
Rnor_5.01317,496,156 - 18,057,247 (+)NCBI
RGSC_v3.41328,709,670 - 29,730,378 (+)RGD
Celera139,876,687 - 10,367,262 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090650   ⟹   XP_038946578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8138,968,048 - 9,976,147 (+)NCBI
mRatBN7.2138,960,951 - 9,962,906 (+)NCBI
RefSeq Acc Id: XM_039090651   ⟹   XP_038946579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8138,968,048 - 9,976,147 (+)NCBI
mRatBN7.2138,960,951 - 9,962,906 (+)NCBI
RefSeq Acc Id: XR_005492233
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8138,968,050 - 9,956,271 (+)NCBI
mRatBN7.2138,960,952 - 9,949,173 (+)NCBI
RefSeq Acc Id: XR_005492234
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8138,968,050 - 9,962,689 (+)NCBI
mRatBN7.2138,960,952 - 9,955,603 (+)NCBI
RefSeq Acc Id: NP_001041330   ⟸   NM_001047865
- Peptide Label: precursor
- UniProtKB: Q0V8T6 (UniProtKB/Swiss-Prot),   A0A8I6G6R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038946578   ⟸   XM_039090650
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G6R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946579   ⟸   XM_039090651
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G6R0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095092   ⟸   ENSRNOT00000111316
Ensembl Acc Id: ENSRNOP00000088891   ⟸   ENSRNOT00000107476
Ensembl Acc Id: ENSRNOP00000076029   ⟸   ENSRNOT00000092965
Ensembl Acc Id: ENSRNOP00000080529   ⟸   ENSRNOT00000118535
Ensembl Acc Id: ENSRNOP00000088436   ⟸   ENSRNOT00000112687
Ensembl Acc Id: ENSRNOP00000087083   ⟸   ENSRNOT00000104126
Ensembl Acc Id: ENSRNOP00000062287   ⟸   ENSRNOT00000067198
Protein Domains
EGF-like   F5/8 type C   Fibrinogen C-terminal   Laminin G   Laminin G-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0V8T6-F1-model_v2 AlphaFold Q0V8T6 1-1305 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559812 AgrOrtholog
BioCyc Gene G2FUF-18700 BioCyc
Ensembl Genes ENSRNOG00000070614 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000092965 ENTREZGENE
  ENSRNOT00000104126 ENTREZGENE
  ENSRNOT00000111316 ENTREZGENE
  ENSRNOT00000111316.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.1000 UniProtKB/Swiss-Prot
  2.60.120.200 UniProtKB/Swiss-Prot
  Galactose-binding domain-like UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  Fibrinogen-like_C UniProtKB/Swiss-Prot
  Fibrinogen_a/b/g_C_dom UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Laminin_G UniProtKB/Swiss-Prot
  Neurexin-related_CASP UniProtKB/Swiss-Prot
KEGG Report rno:297832 UniProtKB/Swiss-Prot
NCBI Gene 297832 ENTREZGENE
PANTHER CONTACTIN-ASSOCIATED PROTEIN-LIKE 5 UniProtKB/Swiss-Prot
  PIKACHURIN-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam EGF UniProtKB/Swiss-Prot
  F5_F8_type_C UniProtKB/Swiss-Prot
  Laminin_G_2 UniProtKB/Swiss-Prot
PhenoGen Cntnap5a PhenoGen
PROSITE EGF_3 UniProtKB/Swiss-Prot
  FA58C_1 UniProtKB/Swiss-Prot
  FA58C_3 UniProtKB/Swiss-Prot
  FIBRINOGEN_C_2 UniProtKB/Swiss-Prot
  LAM_G_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000070614 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot
  LamG UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot
  SSF56496 UniProtKB/Swiss-Prot
UniProt A0A1B0GWV0_RAT UniProtKB/TrEMBL
  A0A8I6ABL9_RAT UniProtKB/TrEMBL
  A0A8I6G6R0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GFN6_RAT UniProtKB/TrEMBL
  CTP5A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Cntnap5a  contactin associated protein-like 5A  LOC100910512  contactin-associated protein like 5-1-like  Data merged from RGD:6498483 737654 PROVISIONAL
2013-05-24 Cntnap5a  contactin associated protein-like 5A  LOC682909  similar to contactin associated protein-like 5 isoform 1  Data merged from RGD:1592834 1643240 APPROVED
2012-07-05 LOC100910512  contactin-associated protein like 5-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-30 Cntnap5a  contactin associated protein-like 5A  RGD1559812  similar to contactin associated protein-like 5 isoform 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559812  similar to contactin associated protein-like 5 isoform 1   RGD1559812_predicted  similar to contactin associated protein-like 5 isoform 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC682909  similar to contactin associated protein-like 5 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1559812_predicted  similar to contactin associated protein-like 5 isoform 1 (predicted)  LOC297832  similar to contactin associated protein-like 5 isoform 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC297832  similar to contactin associated protein-like 5 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL