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Gene: Mro (maestro) Rattus norvegicus

Analyze

Symbol:

Mro

Name:

maestro

RGD ID:

1559803

Description:

Predicted to be located in nucleolus. Orthologous to human MRO (maestro); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 4,4'-diaminodiphenylmethane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AABR07032520.1; hypothetical protein LOC680524; LOC361348; RGD1559803; similar to maestro

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MRO (maestro)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Mro (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mro (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MRO (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MRO (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mro (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MRO (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MRO (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mro (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Mro (maestro)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZMYM5 (zinc finger MYM-type containing 5)	HGNC	OMA
Homo sapiens (human):	CIROP (ciliated left-right organizer metallopeptidase)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	MRO (maestro)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MRO (maestro)	Alliance	DIOPT (HGNC)
Mus musculus (house mouse):	Mro (maestro)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	69,723,764 - 69,742,815 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	69,725,798 - 69,743,031 (+)	Ensembl				GRCr8
mRatBN7.2	18	67,450,186 - 67,467,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	67,450,595 - 67,467,044 (+)	Ensembl				mRatBN7.2
Rnor_6.0	18	69,833,770 - 69,850,164 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	69,841,053 - 69,849,389 (+)	NCBI			rn6	Rnor6.0
Rnor_5.0	18	68,977,912 - 68,993,961 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	70,648,892 - 70,660,961 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	65,628,703 - 65,650,686 (+)	NCBI		Celera
Cytogenetic Map	18	q12.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

hepatocellular carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

4,4'-diaminodiphenylmethane (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aldehydo-D-glucose (ISO)

amiodarone (EXP)

amitrole (EXP)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

clofibrate (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

diethylstilbestrol (EXP)

dorsomorphin (ISO)

epoxiconazole (ISO)

finasteride (EXP)

flutamide (EXP)

fructose (ISO)

glafenine (EXP)

glucose (ISO)

herbicide (ISO)

L-ethionine (EXP)

levonorgestrel (ISO)

methimazole (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

okadaic acid (ISO)

omeprazole (EXP)

paracetamol (ISO)

pentanal (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (EXP,ISO)

propanal (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulforaphane (ISO)

tebuconazole (ISO)

testosterone undecanoate (ISO)

thioacetamide (EXP)

titanium dioxide (EXP,ISO)

triclosan (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nucleolus (ISO)

nucleus (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12889070

Genomics

Comparative Map Data

Mro
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	69,723,764 - 69,742,815 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	69,725,798 - 69,743,031 (+)	Ensembl				GRCr8
mRatBN7.2	18	67,450,186 - 67,467,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	67,450,595 - 67,467,044 (+)	Ensembl				mRatBN7.2
Rnor_6.0	18	69,833,770 - 69,850,164 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	69,841,053 - 69,849,389 (+)	NCBI			rn6	Rnor6.0
Rnor_5.0	18	68,977,912 - 68,993,961 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	70,648,892 - 70,660,961 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	65,628,703 - 65,650,686 (+)	NCBI		Celera
Cytogenetic Map	18	q12.2	NCBI

MRO
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	50,795,130 - 50,825,380 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	50,795,120 - 50,825,449 (-)	Ensembl			hg38	GRCh38
GRCh37	18	48,321,500 - 48,351,750 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	46,578,572 - 46,600,366 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	18	46,578,571 - 46,600,366	NCBI
Celera	18	45,178,236 - 45,208,500 (-)	NCBI		Celera
Cytogenetic Map	18	q21.2	NCBI
HuRef	18	45,176,072 - 45,207,050 (-)	NCBI		HuRef
CHM1_1	18	48,316,965 - 48,347,220 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	50,996,813 - 51,027,082 (-)	NCBI		T2T-CHM13v2.0

Mro
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	73,992,465 - 74,014,405 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	73,992,456 - 74,014,404 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	73,851,826 - 73,881,334 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	73,859,385 - 73,881,333 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	74,019,041 - 74,038,788 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	73,984,754 - 74,004,099 (+)	NCBI		MGSCv36	mm8
Celera	18	75,097,045 - 75,113,615 (+)	NCBI		Celera
Cytogenetic Map	18	E2	NCBI
cM Map	18	50.21	NCBI

Mro
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	35,745,692 - 35,765,887 (-)	Ensembl
ChiLan1.0	NW_004955402	35,745,823 - 35,765,507 (-)	NCBI	ChiLan1.0	ChiLan1.0

MRO
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	68,319,472 - 68,344,255 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	54,012,076 - 54,036,831 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	44,172,007 - 44,202,095 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	47,518,586 - 47,548,647 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	47,522,590 - 47,543,216 (-)	Ensembl			panPan2	panpan1.1

MRO
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	24,073,130 - 24,093,325 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	24,072,415 - 24,088,798 (+)	Ensembl			canFam3	CanFam3.1
ROS_Cfam_1.0	1	23,964,754 - 23,984,902 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	23,964,598 - 23,980,855 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	24,025,195 - 24,045,719 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	23,911,569 - 23,932,073 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	24,184,791 - 24,205,241 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mro
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	37,225,208 - 37,243,326 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936497	12,468,810 - 12,484,070 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936497	12,468,839 - 12,482,645 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MRO
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	100,343,462 - 100,368,354 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	100,342,040 - 100,368,355 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	110,207,703 - 110,217,351 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MRO
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	30,149,163 - 30,177,547 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	30,166,834 - 30,181,570 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	4,280,138 - 4,312,863 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mro
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624778	14,352,856 - 14,359,678 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624778	14,352,071 - 14,359,861 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mro
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	58,112,656 - 58,128,738 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Mro
156 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	200
Count of miRNA genes:	72
Interacting mature miRNAs:	76
Transcripts:	ENSRNOT00000030613, ENSRNOT00000071545, ENSRNOT00000075543
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
1331730	Scl27	Serum cholesterol level QTL 27	3.826		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	54490801	86134022	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
1298072	Cia26	Collagen induced arthritis QTL 26	3.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	64383762	79484311	Rat
631834	Sach3	Saccharin preference QTL 3	3.9	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	18	38575919	83575919	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26822186	71822186	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26822186	71822186	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	45620306	86134022	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26822186	71822186	Rat
7794793	Mcs34	Mammary carcinoma susceptibility QTL 34	1.54		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	18	65635567	85897775	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26822186	71822186	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	48915737	86134022	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	48915737	86134022	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26822186	71822186	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26822186	71822186	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	31990891	76990891	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	45620306	86134022	Rat
2301969	Bp324	Blood pressure QTL 324	4.05		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	61982204	76619168	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31610505	85493247	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	33379158	78379158	Rat
724542	Kidm2	Kidney mass QTL 2	2.6		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	18	61446853	86134022	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	40462383	85462383	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	54490801	76272247	Rat
2312600	Bp341	Blood pressure QTL 341		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	61600384	72538878	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	31990891	76990891	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	33379158	78379158	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	33379158	78379158	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	50795212	86134022	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	33379158	78379158	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26822186	71822186	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31522783	76522783	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	33379158	78379158	Rat
61384	Bp48	Blood pressure QTL 48	19.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	62892257	79484461	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	33379158	78379158	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	33379158	78379158	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	57825243	85493247	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31610505	77371277	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	36121626	81121626	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	31990891	76990891	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	48915737	86134022	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	26415821	71415821	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31644508	79484311	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	65846447	86134022	Rat
1598832	Glom11	Glomerulus QTL 11	2.9		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	53266671	86134022	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	31990891	76990891	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	50795212	86134022	Rat
631675	Iddm15	Insulin dependent diabetes mellitus QTL 15			urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	18	62892257	79484461	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31610505	72538878	Rat

Markers in Region

RH127310

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	67,467,064 - 67,467,263 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	69,849,636 - 69,849,834	NCBI	Rnor6.0
Rnor_5.0	18	68,993,433 - 68,993,631	UniSTS	Rnor5.0
RGSC_v3.4	18	70,660,433 - 70,660,631	UniSTS	RGSC3.4
Celera	18	65,650,158 - 65,650,356	UniSTS
RH 3.4 Map	18	681.4	UniSTS
Cytogenetic Map	18	q12.2	UniSTS

RH137691

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	67,457,754 - 67,457,911 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	69,841,147 - 69,841,303	NCBI	Rnor6.0
Rnor_5.0	18	68,985,014 - 68,985,170	UniSTS	Rnor5.0
RGSC_v3.4	18	70,648,986 - 70,649,142	UniSTS	RGSC3.4
Celera	18	65,640,859 - 65,641,015	UniSTS
RH 3.4 Map	18	686.2	UniSTS
Cytogenetic Map	18	q12.2	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
5	15	28	5	62	21	1	31	36	19	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001437164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001053368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006222622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774142	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008774143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017587889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030613 ⟹ ENSRNOP00000032223

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	69,725,798 - 69,742,811 (+)	Ensembl
mRatBN7.2 Ensembl	18	67,450,595 - 67,467,044 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075543 ⟹ ENSRNOP00000065920

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	69,733,318 - 69,742,810 (+)	Ensembl
mRatBN7.2 Ensembl	18	67,458,203 - 67,467,044 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000125325 ⟹ ENSRNOP00000111167

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	69,725,843 - 69,743,031 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000158396 ⟹ ENSRNOP00000111708

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	69,725,799 - 69,742,807 (+)	Ensembl

RefSeq Acc Id:

XM_063277666 ⟹ XP_063133736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	69,723,764 - 69,742,815 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001424093	(Get FASTA)	NCBI Sequence Viewer
	NP_001424094	(Get FASTA)	NCBI Sequence Viewer
	NP_001424095	(Get FASTA)	NCBI Sequence Viewer
	NP_001424096	(Get FASTA)	NCBI Sequence Viewer
	NP_001424097	(Get FASTA)	NCBI Sequence Viewer
	NP_001424098	(Get FASTA)	NCBI Sequence Viewer
	NP_001424099	(Get FASTA)	NCBI Sequence Viewer
	NP_001424100	(Get FASTA)	NCBI Sequence Viewer
	NP_001424101	(Get FASTA)	NCBI Sequence Viewer
	NP_001424102	(Get FASTA)	NCBI Sequence Viewer
	NP_001424103	(Get FASTA)	NCBI Sequence Viewer
	NP_001424104	(Get FASTA)	NCBI Sequence Viewer
	NP_001424105	(Get FASTA)	NCBI Sequence Viewer
	NP_001424106	(Get FASTA)	NCBI Sequence Viewer
	NP_001424107	(Get FASTA)	NCBI Sequence Viewer
	NP_001424108	(Get FASTA)	NCBI Sequence Viewer
	NP_001424109	(Get FASTA)	NCBI Sequence Viewer
	XP_063133736	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL82912	(Get FASTA)	NCBI Sequence Viewer
	EDL82913	(Get FASTA)	NCBI Sequence Viewer
	EDL82914	(Get FASTA)	NCBI Sequence Viewer
	EDL82915	(Get FASTA)	NCBI Sequence Viewer
	EDL82916	(Get FASTA)	NCBI Sequence Viewer
	EDL82917	(Get FASTA)	NCBI Sequence Viewer
	EDL82918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032223
	ENSRNOP00000032223.7
	ENSRNOP00000065920.4
	ENSRNOP00000111167.1
	ENSRNOP00000111708.1

Ensembl Acc Id:

ENSRNOP00000032223 ⟸ ENSRNOT00000030613

Ensembl Acc Id:

ENSRNOP00000065920 ⟸ ENSRNOT00000075543

RefSeq Acc Id:

XP_063133736 ⟸ XM_063277666

Ensembl Acc Id:

ENSRNOP00000111708 ⟸ ENSRNOT00000158396

Ensembl Acc Id:

ENSRNOP00000111167 ⟸ ENSRNOT00000125325

Protein Domains

Maestro/Maestro-like HEAT-repeats

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0RDR0-F1-model_v2	AlphaFold	M0RDR0	1-252	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559803	AgrOrtholog
BioCyc Gene	G2FUF-7048	BioCyc
Ensembl Genes	ENSRNOG00000024426	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030613	ENTREZGENE
	ENSRNOT00000030613.8	UniProtKB/TrEMBL
	ENSRNOT00000075543.5	UniProtKB/TrEMBL
	ENSRNOT00000125325.1	UniProtKB/TrEMBL
	ENSRNOT00000158396.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/TrEMBL
InterPro	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	HEAT_Maestro	UniProtKB/TrEMBL
	Maestro_heat-like_prot	UniProtKB/TrEMBL
NCBI Gene	361348	ENTREZGENE
PANTHER	PTHR23120	UniProtKB/TrEMBL
	PTHR23120:SF39	UniProtKB/TrEMBL
Pfam	HEAT_MROH2B_C	UniProtKB/TrEMBL
PhenoGen	Mro	PhenoGen
RatGTEx	ENSRNOG00000024426	RatGTEx
Superfamily-SCOP	SSF48371	UniProtKB/TrEMBL
UniProt	A0ABK0M2B3_RAT	UniProtKB/TrEMBL
	A0ABK0M781_RAT	UniProtKB/TrEMBL
	A6KRC9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZXW1	ENTREZGENE, UniProtKB/TrEMBL
	M0R8W5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Mro	maestro	AABR07032520.1		Data merged from RGD:15003588	737654	PROVISIONAL
2019-11-08	AABR07032520.1				Symbol and Name status set to provisional	45752	PROVISIONAL
2013-05-24	Mro	maestro	LOC680524	hypothetical protein LOC680524	Data merged from RGD:1590636	1643240	APPROVED
2008-02-28	Mro	maestro	RGD1559803_predicted	similar to maestro (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC680524	hypothetical protein LOC680524			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1559803_predicted	similar to maestro (predicted)	LOC361348	similar to maestro	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC361348	similar to maestro			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD