Ddias (DNA damage-induced apoptosis suppressor) - Rat Genome Database

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Gene: Ddias (DNA damage-induced apoptosis suppressor) Rattus norvegicus
Analyze
Symbol: Ddias
Name: DNA damage-induced apoptosis suppressor
RGD ID: 1559690
Description: Predicted to be involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to act upstream of or within several processes, including cellular response to hydroperoxide; cellular response to radiation; and negative regulation of fibroblast apoptotic process. Predicted to be active in cytoplasm and nucleus. Orthologous to human DDIAS (DNA damage induced apoptosis suppressor); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC499204; nitric oxide-inducible gene protein; noxin; RGD1559690; similar to hypothetical protein FLJ25416
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81156,318,559 - 156,342,869 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1156,318,563 - 156,342,869 (-)EnsemblGRCr8
mRatBN7.21146,906,150 - 146,930,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1146,906,154 - 146,930,462 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1154,856,212 - 154,880,417 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01162,036,406 - 162,060,611 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01154,909,850 - 154,934,055 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01157,675,754 - 157,700,064 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,675,765 - 157,700,064 (-)Ensemblrn6Rnor6.0
Rnor_5.01163,919,400 - 163,943,710 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41149,685,954 - 149,710,264 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1145,086,401 - 145,110,725 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,4-dioxane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
fructose  (ISO)
glucose  (ISO)
Heliotrine  (EXP)
leflunomide  (ISO)
lidocaine  (EXP)
methimazole  (EXP)
mitomycin C  (ISO)
Moniliformin  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
senecionine  (EXP)
Senkirkine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17515607   PMID:24214091  


Genomics

Comparative Map Data
Ddias
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81156,318,559 - 156,342,869 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1156,318,563 - 156,342,869 (-)EnsemblGRCr8
mRatBN7.21146,906,150 - 146,930,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1146,906,154 - 146,930,462 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1154,856,212 - 154,880,417 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01162,036,406 - 162,060,611 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01154,909,850 - 154,934,055 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01157,675,754 - 157,700,064 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1157,675,765 - 157,700,064 (-)Ensemblrn6Rnor6.0
Rnor_5.01163,919,400 - 163,943,710 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41149,685,954 - 149,710,264 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1145,086,401 - 145,110,725 (-)NCBICelera
Cytogenetic Map1q32NCBI
DDIAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381182,901,736 - 82,934,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1182,899,975 - 82,958,277 (+)Ensemblhg38GRCh38
GRCh371182,612,778 - 82,645,701 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361182,290,417 - 82,323,349 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1179,922,489 - 79,955,453 (+)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1178,910,068 - 78,943,040 (+)NCBIHuRef
CHM1_11182,496,873 - 82,529,829 (+)NCBICHM1_1
T2T-CHM13v2.01182,825,989 - 82,871,120 (+)NCBIT2T-CHM13v2.0
Ddias
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39792,506,734 - 92,523,455 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl792,506,733 - 92,523,455 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38792,857,525 - 92,874,917 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl792,857,525 - 92,874,247 (-)Ensemblmm10GRCm38
MGSCv377100,006,036 - 100,022,742 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36792,732,717 - 92,749,430 (-)NCBIMGSCv36mm8
Celera790,141,403 - 90,162,536 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map751.64NCBI
Ddias
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554149,607,064 - 9,630,781 (-)Ensembl
ChiLan1.0NW_0049554149,607,338 - 9,636,941 (-)NCBIChiLan1.0ChiLan1.0
DDIAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2983,831,812 - 83,868,122 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11184,883,061 - 84,918,946 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01177,967,057 - 77,999,829 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11181,579,459 - 81,612,237 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1181,579,505 - 81,635,075 (+)EnsemblpanPan2panpan1.1
DDIAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12116,192,071 - 16,219,704 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2116,199,901 - 16,219,107 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2116,069,568 - 16,097,810 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02116,380,391 - 16,408,624 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2116,387,547 - 16,408,030 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12116,155,390 - 16,183,606 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02116,235,398 - 16,263,630 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02116,305,538 - 16,333,780 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ddias
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494769,510,179 - 69,529,611 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649811,115,209 - 11,128,948 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649811,115,055 - 11,127,215 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDIAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl917,077,884 - 17,097,588 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1917,077,884 - 17,097,597 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2918,876,626 - 18,896,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDIAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1174,105,911 - 74,139,190 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl174,119,020 - 74,138,862 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604351,566,994 - 51,600,475 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddias
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248456,947,239 - 6,961,901 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248456,946,721 - 6,973,799 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ddias
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12108,320,533 - 108,344,355 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ddias
203 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:56
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000031974
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1131179947176179947Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)1137611478182611478Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
631684Bp117Blood pressure QTL 1178.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1120082258165082258Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1112521556157521556Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1142582336182383862Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1141173126169168317Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1140833106185833106Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1131243790176243790Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1129182274174182274Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1153680016182383862Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1153680016183564652Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1128019551173019551Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436178317588Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1112521556157521556Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1111949780160574007Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436180021436Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1140915717185915717Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat

Markers in Region
AW531221  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21146,919,115 - 146,919,297 (+)MAPPERmRatBN7.2
Rnor_6.01157,688,718 - 157,688,899NCBIRnor6.0
Rnor_5.01163,932,364 - 163,932,545UniSTSRnor5.0
RGSC_v3.41149,698,918 - 149,699,099UniSTSRGSC3.4
Celera1145,099,379 - 145,099,560UniSTS
RH 3.4 Map11140.8UniSTS
Cytogenetic Map1q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 64 163 91 90 59 89 59 6 340 185 11 142 72 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000031974   ⟹   ENSRNOP00000030379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1156,318,563 - 156,342,869 (-)Ensembl
mRatBN7.2 Ensembl1146,906,154 - 146,930,462 (-)Ensembl
Rnor_6.0 Ensembl1157,675,765 - 157,700,064 (-)Ensembl
RefSeq Acc Id: NM_001126294   ⟹   NP_001119766
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,318,559 - 156,342,869 (-)NCBI
mRatBN7.21146,906,150 - 146,930,462 (-)NCBI
Rnor_6.01157,675,754 - 157,700,064 (-)NCBI
Rnor_5.01163,919,400 - 163,943,710 (-)NCBI
RGSC_v3.41149,685,954 - 149,710,264 (-)RGD
Celera1145,086,401 - 145,110,725 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001119766 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66470 (Get FASTA)   NCBI Sequence Viewer  
  EDM18513 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030379
  ENSRNOP00000030379.3
RefSeq Acc Id: NP_001119766   ⟸   NM_001126294
- UniProtKB: B2GV00 (UniProtKB/TrEMBL),   A6I666 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030379   ⟸   ENSRNOT00000031974
Protein Domains
Replication factor A C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GV00-F1-model_v2 AlphaFold B2GV00 1-883 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690198
Promoter ID:EPDNEW_R723
Type:multiple initiation site
Name:Ddias_1
Description:DNA damage-induced apoptosis suppressor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01157,700,082 - 157,700,142EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559690 AgrOrtholog
BioCyc Gene G2FUF-58490 BioCyc
Ensembl Genes ENSRNOG00000022521 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031974 ENTREZGENE
  ENSRNOT00000031974.6 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9088340 IMAGE-MGC_LOAD
InterPro DDIAS UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Rep_factor-A_C UniProtKB/TrEMBL
KEGG Report rno:499204 UniProtKB/TrEMBL
MGC_CLONE MGC:187850 IMAGE-MGC_LOAD
NCBI Gene 499204 ENTREZGENE
PANTHER DNA DAMAGE-INDUCED APOPTOSIS SUPPRESSOR PROTEIN UniProtKB/TrEMBL
  PTHR35537 UniProtKB/TrEMBL
Pfam Rep_fac-A_C UniProtKB/TrEMBL
PhenoGen Ddias PhenoGen
RatGTEx ENSRNOG00000022521 RatGTEx
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
UniProt A6I666 ENTREZGENE, UniProtKB/TrEMBL
  B2GV00 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-06-06 Ddias  DNA damage-induced apoptosis suppressor  RGD1559690  similar to hypothetical protein FLJ25416  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559690  similar to hypothetical protein FLJ25416   RGD1559690_predicted  similar to hypothetical protein FLJ25416 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559690_predicted  similar to hypothetical protein FLJ25416 (predicted)  LOC499204  similar to hypothetical protein FLJ25416  Symbol and Name status set to approved 1299863 APPROVED