Traf7 (TNF receptor associated factor 7) - Rat Genome Database

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Gene: Traf7 (TNF receptor associated factor 7) Rattus norvegicus
Analyze
Symbol: Traf7
Name: TNF receptor associated factor 7
RGD ID: 1559653
Description: Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of neuron apoptotic process. Predicted to be located in several cellular components, including cytosol; nucleus; and perinuclear region of cytoplasm. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in adenomatoid tumor; hepatocellular carcinoma; and peritoneal mesothelioma. Orthologous to human TRAF7 (TNF receptor associated factor 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase TRAF7; LOC360491; RGD1559653; similar to ring finger and WD repeat domain 1 isoform 1; Tnf receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,038,117 - 14,056,832 (-)NCBIGRCr8
mRatBN7.21013,533,570 - 13,552,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,533,570 - 13,552,203 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,280,130 - 18,298,622 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,768,975 - 17,787,467 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,268,162 - 13,286,654 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,874,444 - 13,893,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,691,429 - 13,710,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,760,687 - 13,779,228 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,213,849 - 13,232,354 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Goode B, etal., Mod Pathol. 2018 Apr;31(4):660-673. doi: 10.1038/modpathol.2017.153. Epub 2017 Nov 17.
3. TRAF7 enhances ubiquitin-degradation of KLF4 to promote hepatocellular carcinoma progression. He H, etal., Cancer Lett. 2020 Jan 28;469:380-389. doi: 10.1016/j.canlet.2019.11.012. Epub 2019 Nov 12.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42. Stevers M, etal., Mod Pathol. 2019 Jan;32(1):88-99. doi: 10.1038/s41379-018-0127-2. Epub 2018 Aug 31.
8. Up-regulation of TNF Receptor-associated Factor 7 after spinal cord injury in rats may have implication for neuronal apoptosis. Xu D, etal., Neuropeptides. 2018 Oct;71:81-89. doi: 10.1016/j.npep.2018.08.001. Epub 2018 Aug 8.
Additional References at PubMed
PMID:12477932   PMID:14743216   PMID:15001576   PMID:16162816   PMID:29961569  


Genomics

Comparative Map Data
Traf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,038,117 - 14,056,832 (-)NCBIGRCr8
mRatBN7.21013,533,570 - 13,552,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,533,570 - 13,552,203 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,280,130 - 18,298,622 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,768,975 - 17,787,467 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,268,162 - 13,286,654 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,874,444 - 13,893,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,691,429 - 13,710,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,760,687 - 13,779,228 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,213,849 - 13,232,354 (-)NCBICelera
Cytogenetic Map10q12NCBI
TRAF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,155,782 - 2,178,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,155,698 - 2,178,129 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,205,783 - 2,228,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,145,800 - 2,168,131 (+)NCBINCBI36Build 36hg18NCBI36
Celera162,420,218 - 2,442,550 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,132,066 - 2,154,384 (+)NCBIHuRef
CHM1_1162,205,774 - 2,228,103 (+)NCBICHM1_1
T2T-CHM13v2.0162,178,244 - 2,200,598 (+)NCBIT2T-CHM13v2.0
Traf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,727,824 - 24,746,912 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,727,536 - 24,746,912 (-)EnsemblGRCm39 Ensembl
GRCm381724,508,850 - 24,527,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,508,562 - 24,527,938 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,645,795 - 24,664,883 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,236,450 - 24,255,430 (-)NCBIMGSCv36mm8
Celera1725,024,825 - 25,044,110 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.4NCBI
Traf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,092,955 - 15,112,840 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,092,955 - 15,112,842 (-)NCBIChiLan1.0ChiLan1.0
TRAF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,658,025 - 2,679,959 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,439,363 - 6,460,772 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,013,831 - 1,036,486 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,266,213 - 2,279,031 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,266,194 - 2,279,031 (+)Ensemblpanpan1.1panPan2
TRAF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,788,451 - 38,805,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,788,454 - 38,962,167 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,027,602 - 40,044,841 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,096,963 - 39,114,204 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,096,963 - 39,114,105 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,781,803 - 38,799,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,754,119 - 38,771,345 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,232,866 - 39,250,103 (-)NCBIUU_Cfam_GSD_1.0
Traf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,822,976 - 104,841,154 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366941,868,309 - 1,886,772 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,810,606 - 39,828,395 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,811,803 - 39,828,450 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,353,140 - 42,369,754 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRAF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,051,247 - 2,072,763 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,059,349 - 2,071,297 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,989,286 - 29,010,804 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Traf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462491379,423 - 100,279 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462491379,423 - 100,301 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Traf7
23 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000004192
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat

Markers in Region
RH130595  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,553,457 - 13,553,669 (+)MAPPERmRatBN7.2
Rnor_6.01013,894,331 - 13,894,542NCBIRnor6.0
Rnor_5.01013,711,316 - 13,711,527UniSTSRnor5.0
RGSC_v3.41013,780,562 - 13,780,773UniSTSRGSC3.4
Celera1013,233,688 - 13,233,899UniSTS
Cytogenetic Map10q12UniSTS
RH132048  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,552,609 - 13,553,007 (+)MAPPERmRatBN7.2
Rnor_6.01013,893,483 - 13,893,880NCBIRnor6.0
Rnor_5.01013,710,468 - 13,710,865UniSTSRnor5.0
RGSC_v3.41013,779,714 - 13,780,111UniSTSRGSC3.4
Celera1013,232,840 - 13,233,237UniSTS
RH 3.4 Map10171.7UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 41 25 19 25 2 4 74 35 39 11 2
Low 2 16 16 16 6 7 2 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000004192   ⟹   ENSRNOP00000004192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,582 - 13,552,124 (-)Ensembl
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097263   ⟹   ENSRNOP00000094607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,584 - 13,552,203 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100967   ⟹   ENSRNOP00000081332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,586 - 13,543,746 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107920   ⟹   ENSRNOP00000089242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,582 - 13,542,578 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115734   ⟹   ENSRNOP00000082217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,570 - 13,552,125 (-)Ensembl
RefSeq Acc Id: NM_001127548   ⟹   NP_001121020
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,117 - 14,056,694 (-)NCBI
mRatBN7.21013,533,570 - 13,552,147 (-)NCBI
Rnor_6.01013,874,456 - 13,892,997 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
RGSC_v3.41013,760,687 - 13,779,228 (-)RGD
Celera1013,213,849 - 13,232,354 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415153   ⟹   NP_001402082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,117 - 14,056,694 (-)NCBI
mRatBN7.21013,533,570 - 13,552,147 (-)NCBI
RefSeq Acc Id: XM_006245983   ⟹   XP_006246045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,759 (-)NCBI
mRatBN7.21013,533,570 - 13,552,219 (-)NCBI
Rnor_6.01013,874,456 - 13,893,088 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245985   ⟹   XP_006246047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,274 (-)NCBI
mRatBN7.21013,533,570 - 13,543,746 (-)NCBI
Rnor_6.01013,874,444 - 13,884,573 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245987   ⟹   XP_006246049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,274 (-)NCBI
mRatBN7.21013,533,570 - 13,543,746 (-)NCBI
Rnor_6.01013,874,444 - 13,884,573 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245991   ⟹   XP_006246053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,287 (-)NCBI
mRatBN7.21013,533,570 - 13,543,740 (-)NCBI
Rnor_6.01013,874,456 - 13,884,510 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245992   ⟹   XP_006246054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,258 (-)NCBI
mRatBN7.21013,533,570 - 13,543,706 (-)NCBI
Rnor_6.01013,874,456 - 13,884,528 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245993   ⟹   XP_006246055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,287 (-)NCBI
mRatBN7.21013,533,570 - 13,543,740 (-)NCBI
Rnor_6.01013,874,456 - 13,884,504 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597366   ⟹   XP_017452855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,760 (-)NCBI
mRatBN7.21013,533,570 - 13,552,223 (-)NCBI
Rnor_6.01013,874,456 - 13,893,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086269   ⟹   XP_038942197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,760 (-)NCBI
mRatBN7.21013,533,570 - 13,552,223 (-)NCBI
RefSeq Acc Id: XM_039086271   ⟹   XP_038942199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,795 (-)NCBI
mRatBN7.21013,533,570 - 13,552,290 (-)NCBI
RefSeq Acc Id: XM_063269306   ⟹   XP_063125376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,292 (-)NCBI
RefSeq Acc Id: XM_063269307   ⟹   XP_063125377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,292 (-)NCBI
RefSeq Acc Id: XM_063269308   ⟹   XP_063125378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,732 (-)NCBI
RefSeq Acc Id: XM_063269309   ⟹   XP_063125379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,832 (-)NCBI
RefSeq Acc Id: NP_001121020   ⟸   NM_001127548
- Peptide Label: isoform 2
- UniProtKB: B1WBW7 (UniProtKB/TrEMBL),   F7FIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246045   ⟸   XM_006245983
- Peptide Label: isoform X1
- UniProtKB: F7FIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246054   ⟸   XM_006245992
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246047   ⟸   XM_006245985
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246049   ⟸   XM_006245987
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246053   ⟸   XM_006245991
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246055   ⟸   XM_006245993
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452855   ⟸   XM_017597366
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000004192   ⟸   ENSRNOT00000004192
RefSeq Acc Id: XP_038942199   ⟸   XM_039086271
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942197   ⟸   XM_039086269
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000081332   ⟸   ENSRNOT00000100967
RefSeq Acc Id: ENSRNOP00000082217   ⟸   ENSRNOT00000115734
RefSeq Acc Id: ENSRNOP00000089242   ⟸   ENSRNOT00000107920
RefSeq Acc Id: ENSRNOP00000094607   ⟸   ENSRNOT00000097263
RefSeq Acc Id: NP_001402082   ⟸   NM_001415153
- Peptide Label: isoform 1
- UniProtKB: F7FIY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125379   ⟸   XM_063269309
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063125378   ⟸   XM_063269308
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063125377   ⟸   XM_063269307
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063125376   ⟸   XM_063269306
- Peptide Label: isoform X4
Protein Domains
RING-type   TRAF-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WBW7-F1-model_v2 AlphaFold B1WBW7 1-669 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697014
Promoter ID:EPDNEW_R7539
Type:initiation region
Name:Traf7_1
Description:TNF receptor associated factor 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01013,893,020 - 13,893,080EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559653 AgrOrtholog
BioCyc Gene G2FUF-25853 BioCyc
Ensembl Genes ENSRNOG00000003131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004192 ENTREZGENE
  ENSRNOT00000004192.5 UniProtKB/TrEMBL
  ENSRNOT00000097263.1 UniProtKB/TrEMBL
  ENSRNOT00000100967.1 UniProtKB/TrEMBL
  ENSRNOT00000107920.1 UniProtKB/TrEMBL
  ENSRNOT00000115734.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8369808 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
KEGG Report rno:360491 UniProtKB/TrEMBL
MGC_CLONE MGC:187654 IMAGE-MGC_LOAD
NCBI Gene 360491 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRAF7 UniProtKB/TrEMBL
  WD40 REPEAT PROTEIN UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PhenoGen Traf7 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003131 RatGTEx
SMART RING UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A8I5ZSA7_RAT UniProtKB/TrEMBL
  A0A8I5ZTK4_RAT UniProtKB/TrEMBL
  A0A8I6A9T1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMJ5 ENTREZGENE, UniProtKB/TrEMBL
  B1WBW7 ENTREZGENE, UniProtKB/TrEMBL
  F7FIY6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Traf7  TNF receptor associated factor 7  Traf7  TNF receptor-associated factor 7, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Traf7  TNF receptor-associated factor 7, E3 ubiquitin protein ligase  Traf7  Tnf receptor-associated factor 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Traf7  Tnf receptor-associated factor 7   Traf7_predicted  Tnf receptor-associated factor 7 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Traf7_predicted  Tnf receptor-associated factor 7 (predicted)  RGD1559653_predicted  similar to ring finger and WD repeat domain 1 isoform 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1559653_predicted  similar to ring finger and WD repeat domain 1 isoform 1 (predicted)  LOC360491  similar to ring finger and WD repeat domain 1 isoform 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360491  similar to ring finger and WD repeat domain 1 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL