Traf7 (TNF receptor associated factor 7) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways
Gene: Traf7 (TNF receptor associated factor 7) Rattus norvegicus
Analyze
Symbol: Traf7
Name: TNF receptor associated factor 7
RGD ID: 1559653
Description: Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of neuron apoptotic process. Predicted to be located in cytosol and perinuclear region of cytoplasm. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adenomatoid tumor; hepatocellular carcinoma; and peritoneal mesothelioma. Orthologous to human TRAF7 (TNF receptor associated factor 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase TRAF7; LOC360491; RGD1559653; similar to ring finger and WD repeat domain 1 isoform 1; Tnf receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,038,117 - 14,056,832 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,038,117 - 14,056,694 (-)EnsemblGRCr8
mRatBN7.21013,533,570 - 13,552,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,533,570 - 13,552,203 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,280,130 - 18,298,622 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,768,975 - 17,787,467 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,268,162 - 13,286,654 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,874,444 - 13,893,090 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)Ensemblrn6Rnor6.0
Rnor_5.01013,691,429 - 13,710,062 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,760,687 - 13,779,228 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,213,849 - 13,232,354 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse:




References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Goode B, etal., Mod Pathol. 2018 Apr;31(4):660-673. doi: 10.1038/modpathol.2017.153. Epub 2017 Nov 17.
3. TRAF7 enhances ubiquitin-degradation of KLF4 to promote hepatocellular carcinoma progression. He H, etal., Cancer Lett. 2020 Jan 28;469:380-389. doi: 10.1016/j.canlet.2019.11.012. Epub 2019 Nov 12.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42. Stevers M, etal., Mod Pathol. 2019 Jan;32(1):88-99. doi: 10.1038/s41379-018-0127-2. Epub 2018 Aug 31.
8. Up-regulation of TNF Receptor-associated Factor 7 after spinal cord injury in rats may have implication for neuronal apoptosis. Xu D, etal., Neuropeptides. 2018 Oct;71:81-89. doi: 10.1016/j.npep.2018.08.001. Epub 2018 Aug 8.
Additional References at PubMed
PMID:12477932   PMID:14743216   PMID:15001576   PMID:16162816   PMID:29961569  


Genomics

Comparative Map Data
Traf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,038,117 - 14,056,832 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,038,117 - 14,056,694 (-)EnsemblGRCr8
mRatBN7.21013,533,570 - 13,552,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,533,570 - 13,552,203 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,280,130 - 18,298,622 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,768,975 - 17,787,467 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,268,162 - 13,286,654 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,874,444 - 13,893,090 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)Ensemblrn6Rnor6.0
Rnor_5.01013,691,429 - 13,710,062 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,760,687 - 13,779,228 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,213,849 - 13,232,354 (-)NCBICelera
Cytogenetic Map10q12NCBI
TRAF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,155,782 - 2,178,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,155,692 - 2,178,129 (+)Ensemblhg38GRCh38
GRCh37162,205,783 - 2,228,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,145,800 - 2,168,131 (+)NCBIBuild 36Build 36hg18NCBI36
Celera162,420,218 - 2,442,550 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,132,066 - 2,154,384 (+)NCBIHuRef
CHM1_1162,205,774 - 2,228,103 (+)NCBICHM1_1
T2T-CHM13v2.0162,178,244 - 2,200,598 (+)NCBIT2T-CHM13v2.0
Traf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,727,824 - 24,746,912 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,727,536 - 24,746,912 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381724,508,850 - 24,527,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,508,562 - 24,527,938 (-)Ensemblmm10GRCm38
MGSCv371724,645,795 - 24,664,883 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361724,236,450 - 24,255,430 (-)NCBIMGSCv36mm8
Celera1725,024,825 - 25,044,110 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.4NCBI
Traf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,092,955 - 15,112,840 (-)Ensembl
ChiLan1.0NW_00495544215,092,955 - 15,112,842 (-)NCBIChiLan1.0ChiLan1.0
TRAF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,658,025 - 2,679,959 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,439,363 - 6,460,772 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,013,831 - 1,036,486 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,266,213 - 2,279,031 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,266,194 - 2,279,031 (+)EnsemblpanPan2panpan1.1
TRAF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,788,451 - 38,805,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,788,454 - 38,962,167 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha640,027,602 - 40,044,841 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0639,096,963 - 39,114,204 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,096,963 - 39,114,105 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,781,803 - 38,799,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,754,119 - 38,771,345 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,232,866 - 39,250,103 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Traf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,822,976 - 104,841,154 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,868,309 - 1,886,427 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,868,309 - 1,886,772 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,810,606 - 39,828,395 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,811,803 - 39,828,450 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,353,140 - 42,369,754 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRAF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,051,247 - 2,072,763 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,059,349 - 2,071,297 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606828,989,286 - 29,010,804 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Traf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462491379,423 - 100,279 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462491379,423 - 100,301 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Traf7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v191,792,688 - 1,811,200 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Traf7
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000004192
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
RH130595  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,553,457 - 13,553,669 (+)MAPPERmRatBN7.2
Rnor_6.01013,894,331 - 13,894,542NCBIRnor6.0
Rnor_5.01013,711,316 - 13,711,527UniSTSRnor5.0
RGSC_v3.41013,780,562 - 13,780,773UniSTSRGSC3.4
Celera1013,233,688 - 13,233,899UniSTS
Cytogenetic Map10q12UniSTS
RH132048  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81014,057,156 - 14,057,554 (+)Marker Load Pipeline
mRatBN7.21013,552,609 - 13,553,007 (+)MAPPERmRatBN7.2
Rnor_6.01013,893,483 - 13,893,880NCBIRnor6.0
Rnor_5.01013,710,468 - 13,710,865UniSTSRnor5.0
RGSC_v3.41013,779,714 - 13,780,111UniSTSRGSC3.4
Celera1013,232,840 - 13,233,237UniSTS
RH 3.4 Map10171.7UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC161916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000004192   ⟹   ENSRNOP00000004192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,582 - 13,552,124 (-)Ensembl
Rnor_6.0 Ensembl1013,874,456 - 13,892,997 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097263   ⟹   ENSRNOP00000094607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1014,038,117 - 14,056,694 (-)Ensembl
mRatBN7.2 Ensembl1013,533,584 - 13,552,203 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100967   ⟹   ENSRNOP00000081332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,586 - 13,543,746 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107920   ⟹   ENSRNOP00000089242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,533,582 - 13,542,578 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115734   ⟹   ENSRNOP00000082217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1014,038,117 - 14,056,694 (-)Ensembl
mRatBN7.2 Ensembl1013,533,570 - 13,552,125 (-)Ensembl
RefSeq Acc Id: NM_001127548   ⟹   NP_001121020
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,117 - 14,056,694 (-)NCBI
mRatBN7.21013,533,570 - 13,552,147 (-)NCBI
Rnor_6.01013,874,456 - 13,892,997 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
RGSC_v3.41013,760,687 - 13,779,228 (-)RGD
Celera1013,213,849 - 13,232,354 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415153   ⟹   NP_001402082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,117 - 14,056,694 (-)NCBI
mRatBN7.21013,533,570 - 13,552,147 (-)NCBI
RefSeq Acc Id: XM_006245983   ⟹   XP_006246045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,759 (-)NCBI
mRatBN7.21013,533,570 - 13,552,219 (-)NCBI
Rnor_6.01013,874,456 - 13,893,088 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245985   ⟹   XP_006246047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,274 (-)NCBI
mRatBN7.21013,533,570 - 13,543,746 (-)NCBI
Rnor_6.01013,874,444 - 13,884,573 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245987   ⟹   XP_006246049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,274 (-)NCBI
mRatBN7.21013,533,570 - 13,543,746 (-)NCBI
Rnor_6.01013,874,444 - 13,884,573 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245991   ⟹   XP_006246053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,287 (-)NCBI
mRatBN7.21013,533,570 - 13,543,740 (-)NCBI
Rnor_6.01013,874,456 - 13,884,510 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245992   ⟹   XP_006246054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,258 (-)NCBI
mRatBN7.21013,533,570 - 13,543,706 (-)NCBI
Rnor_6.01013,874,456 - 13,884,528 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006245993   ⟹   XP_006246055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,287 (-)NCBI
mRatBN7.21013,533,570 - 13,543,740 (-)NCBI
Rnor_6.01013,874,456 - 13,884,504 (-)NCBI
Rnor_5.01013,691,429 - 13,710,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597366   ⟹   XP_017452855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,760 (-)NCBI
mRatBN7.21013,533,570 - 13,552,223 (-)NCBI
Rnor_6.01013,874,456 - 13,893,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086269   ⟹   XP_038942197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,760 (-)NCBI
mRatBN7.21013,533,570 - 13,552,223 (-)NCBI
RefSeq Acc Id: XM_039086271   ⟹   XP_038942199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,795 (-)NCBI
mRatBN7.21013,533,570 - 13,552,290 (-)NCBI
RefSeq Acc Id: XM_063269306   ⟹   XP_063125376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,292 (-)NCBI
RefSeq Acc Id: XM_063269307   ⟹   XP_063125377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,048,292 (-)NCBI
RefSeq Acc Id: XM_063269308   ⟹   XP_063125378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,732 (-)NCBI
RefSeq Acc Id: XM_063269309   ⟹   XP_063125379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,038,129 - 14,056,832 (-)NCBI
RefSeq Acc Id: NP_001121020   ⟸   NM_001127548
- Peptide Label: isoform 2
- UniProtKB: B1WBW7 (UniProtKB/TrEMBL),   F7FIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246045   ⟸   XM_006245983
- Peptide Label: isoform X1
- UniProtKB: F7FIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246054   ⟸   XM_006245992
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246047   ⟸   XM_006245985
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246049   ⟸   XM_006245987
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246053   ⟸   XM_006245991
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246055   ⟸   XM_006245993
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452855   ⟸   XM_017597366
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004192   ⟸   ENSRNOT00000004192
RefSeq Acc Id: XP_038942199   ⟸   XM_039086271
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942197   ⟸   XM_039086269
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000081332   ⟸   ENSRNOT00000100967
Ensembl Acc Id: ENSRNOP00000082217   ⟸   ENSRNOT00000115734
Ensembl Acc Id: ENSRNOP00000089242   ⟸   ENSRNOT00000107920
Ensembl Acc Id: ENSRNOP00000094607   ⟸   ENSRNOT00000097263
RefSeq Acc Id: NP_001402082   ⟸   NM_001415153
- Peptide Label: isoform 1
- UniProtKB: F7FIY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125379   ⟸   XM_063269309
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125378   ⟸   XM_063269308
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125377   ⟸   XM_063269307
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125376   ⟸   XM_063269306
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A9T1 (UniProtKB/TrEMBL)
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WBW7-F1-model_v2 AlphaFold B1WBW7 1-669 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697014
Promoter ID:EPDNEW_R7539
Type:initiation region
Name:Traf7_1
Description:TNF receptor associated factor 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01013,893,020 - 13,893,080EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559653 AgrOrtholog
BioCyc Gene G2FUF-25853 BioCyc
Ensembl Genes ENSRNOG00000003131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000097263 ENTREZGENE
  ENSRNOT00000097263.2 UniProtKB/TrEMBL
  ENSRNOT00000115734 ENTREZGENE
  ENSRNOT00000115734.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8369808 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  Znf-RING_LisH UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
  Znf_TRAF UniProtKB/TrEMBL
KEGG Report rno:360491 UniProtKB/TrEMBL
MGC_CLONE MGC:187654 IMAGE-MGC_LOAD
NCBI Gene 360491 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRAF7 UniProtKB/TrEMBL
  WD40 REPEAT PROTEIN UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PhenoGen Traf7 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
  ZF_TRAF UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003131 RatGTEx
SMART RING UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A8I5ZTK4_RAT UniProtKB/TrEMBL
  A0A8I6A9T1 ENTREZGENE
  A0A8I6AMJ5 ENTREZGENE, UniProtKB/TrEMBL
  B1WBW7 ENTREZGENE, UniProtKB/TrEMBL
  F7FIY6 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Traf7  TNF receptor associated factor 7  Traf7  TNF receptor-associated factor 7, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Traf7  TNF receptor-associated factor 7, E3 ubiquitin protein ligase  Traf7  Tnf receptor-associated factor 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Traf7  Tnf receptor-associated factor 7   Traf7_predicted  Tnf receptor-associated factor 7 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Traf7_predicted  Tnf receptor-associated factor 7 (predicted)  RGD1559653_predicted  similar to ring finger and WD repeat domain 1 isoform 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1559653_predicted  similar to ring finger and WD repeat domain 1 isoform 1 (predicted)  LOC360491  similar to ring finger and WD repeat domain 1 isoform 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360491  similar to ring finger and WD repeat domain 1 isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL