Klhl13 (kelch-like family member 13) - Rat Genome Database

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Gene: Klhl13 (kelch-like family member 13) Rattus norvegicus
Analyze
Symbol: Klhl13
Name: kelch-like family member 13
RGD ID: 1559646
Description: Predicted to enable cullin family protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination and regulation of cytokinesis. Predicted to be located in cytosol. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KLHL13 (kelch like family member 13); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kelch-like 13; kelch-like protein 13
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Klhl13Tn(sb-T2/Bart3)2.176Mcwi
Genetic Models: F344-Klhl13Tn(sb-T2/Bart3)2.176Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X118,747,298 - 118,912,279 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX118,747,298 - 118,855,035 (-)EnsemblGRCr8
mRatBN7.2X113,942,309 - 114,107,299 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX113,942,309 - 114,107,321 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX115,990,571 - 116,147,826 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X119,481,828 - 119,639,088 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X117,035,451 - 117,192,707 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X121,578,965 - 121,735,014 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX121,578,940 - 121,731,543 (-)Ensemblrn6Rnor6.0
Rnor_5.0X121,716,856 - 121,876,640 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X10,344,050 - 10,424,665 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX113,160,518 - 113,316,894 (-)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,4-dichloroaniline  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
carbon nanotube  (ISO)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
gallic acid  (ISO)
genistein  (EXP)
hydrogen peroxide  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
lead(0)  (ISO)
Licochalcone B  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
propiconazole  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
XL147  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14528312   PMID:17543862  


Genomics

Comparative Map Data
Klhl13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X118,747,298 - 118,912,279 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX118,747,298 - 118,855,035 (-)EnsemblGRCr8
mRatBN7.2X113,942,309 - 114,107,299 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX113,942,309 - 114,107,321 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX115,990,571 - 116,147,826 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X119,481,828 - 119,639,088 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X117,035,451 - 117,192,707 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X121,578,965 - 121,735,014 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX121,578,940 - 121,731,543 (-)Ensemblrn6Rnor6.0
Rnor_5.0X121,716,856 - 121,876,640 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X10,344,050 - 10,424,665 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX113,160,518 - 113,316,894 (-)NCBICelera
Cytogenetic MapXq34NCBI
KLHL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X117,897,813 - 118,117,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX117,897,794 - 118,117,340 (-)Ensemblhg38GRCh38
GRCh37X117,031,776 - 117,251,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X116,915,804 - 116,990,881 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X116,813,657 - 116,888,735NCBI
CeleraX117,486,583 - 117,706,100 (-)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX106,526,310 - 106,745,823 (-)NCBIHuRef
CHM1_1X116,942,701 - 117,162,205 (-)NCBICHM1_1
T2T-CHM13v2.0X116,275,375 - 116,494,936 (-)NCBIT2T-CHM13v2.0
Klhl13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X23,085,510 - 23,231,340 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX23,085,510 - 23,231,321 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X23,219,271 - 23,365,161 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX23,219,271 - 23,365,082 (-)Ensemblmm10GRCm38
MGSCv37X22,796,397 - 22,942,179 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X22,376,230 - 22,522,012 (-)NCBIMGSCv36mm8
CeleraX21,314,201 - 21,459,747 (-)NCBICelera
Cytogenetic MapXA2NCBI
cM MapX17.22NCBI
Klhl13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555341,906,928 - 2,127,485 (+)Ensembl
ChiLan1.0NW_0049555341,906,783 - 2,127,266 (+)NCBIChiLan1.0ChiLan1.0
KLHL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X117,254,392 - 117,473,257 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X117,258,000 - 117,476,865 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X106,904,105 - 107,122,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X117,320,192 - 117,538,413 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX117,320,192 - 117,450,771 (-)EnsemblpanPan2panpan1.1
KLHL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X90,138,375 - 90,355,105 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX90,139,103 - 90,355,188 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX76,279,833 - 76,496,370 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X91,884,816 - 92,095,044 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX91,884,337 - 92,095,004 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X89,332,313 - 89,549,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X91,091,066 - 91,300,985 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X90,826,306 - 91,036,222 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X89,133,964 - 89,315,675 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647911,744,058 - 11,853,558 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647911,671,773 - 11,853,531 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX96,544,095 - 96,744,764 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X96,545,099 - 96,950,242 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X114,935,916 - 115,075,998 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606530,654,763 - 30,848,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248951,713,999 - 1,832,818 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248951,714,144 - 1,917,653 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl13
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X99,467,684 - 99,580,480 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Klhl13
746 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1903
Count of miRNA genes:322
Interacting mature miRNAs:431
Transcripts:ENSRNOT00000018788, ENSRNOT00000063868, ENSRNOT00000065459, ENSRNOT00000067114
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
AI451128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X113,942,335 - 113,942,622 (+)MAPPERmRatBN7.2
Rnor_6.0X121,578,992 - 121,579,278NCBIRnor6.0
Rnor_5.0X121,716,883 - 121,717,169UniSTSRnor5.0
RGSC_v3.4X10,424,352 - 10,424,638UniSTSRGSC3.4
CeleraX113,160,545 - 113,160,831UniSTS
Cytogenetic MapXq12UniSTS
KLHL13  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X118,779,237 - 118,779,973 (+)Marker Load Pipeline
mRatBN7.2X113,974,248 - 113,974,984 (+)MAPPERmRatBN7.2
Rnor_6.0X121,607,676 - 121,608,411NCBIRnor6.0
Rnor_5.0X121,746,152 - 121,746,887UniSTSRnor5.0
RGSC_v3.4X10,389,642 - 10,390,377UniSTSRGSC3.4
CeleraX113,191,116 - 113,191,851UniSTS
Cytogenetic MapXq12UniSTS


Genetic Models
This gene Klhl13 is modified in the following models/strains:
F344-Klhl13Tn(sb-T2/Bart3)2.176Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 86 59 6 349 186 11 144 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001401133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002727661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003752130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003754837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006257444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039100612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC104685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018788   ⟹   ENSRNOP00000018788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,855,035 (-)Ensembl
mRatBN7.2 EnsemblX113,942,339 - 114,107,302 (-)Ensembl
Rnor_6.0 EnsemblX121,578,940 - 121,731,543 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094168   ⟹   ENSRNOP00000088688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,825,125 (-)Ensembl
mRatBN7.2 EnsemblX113,942,309 - 114,020,529 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094972   ⟹   ENSRNOP00000088723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,836,380 (-)Ensembl
mRatBN7.2 EnsemblX113,942,310 - 114,031,404 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101919   ⟹   ENSRNOP00000090232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,825,481 (-)Ensembl
mRatBN7.2 EnsemblX113,942,309 - 114,020,529 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106563   ⟹   ENSRNOP00000082058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,801,672 (-)Ensembl
mRatBN7.2 EnsemblX113,942,309 - 113,996,687 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111718   ⟹   ENSRNOP00000084359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX118,747,298 - 118,855,035 (-)Ensembl
mRatBN7.2 EnsemblX113,942,310 - 114,107,321 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114825   ⟹   ENSRNOP00000087922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX113,943,373 - 114,107,302 (-)Ensembl
RefSeq Acc Id: NM_001100854   ⟹   NP_001094324
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,912,279 (-)NCBI
mRatBN7.2X113,942,309 - 114,107,299 (-)NCBI
RefSeq Acc Id: NM_001401131   ⟹   NP_001388060
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,912,279 (-)NCBI
mRatBN7.2X113,942,309 - 114,107,299 (-)NCBI
RefSeq Acc Id: NM_001401132   ⟹   NP_001388061
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,825,481 (-)NCBI
mRatBN7.2X113,942,309 - 114,020,497 (-)NCBI
RefSeq Acc Id: NM_001401133   ⟹   NP_001388062
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,912,279 (-)NCBI
mRatBN7.2X113,942,309 - 114,107,299 (-)NCBI
RefSeq Acc Id: XM_003752130   ⟹   XP_003752178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,837,808 (-)NCBI
mRatBN7.2X113,942,313 - 114,031,297 (-)NCBI
Rnor_6.0X121,578,969 - 121,665,004 (-)NCBI
Rnor_5.0X121,716,856 - 121,876,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257444   ⟹   XP_006257506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,824,747 (-)NCBI
mRatBN7.2X113,942,313 - 114,019,693 (-)NCBI
Rnor_6.0X121,578,969 - 121,651,482 (-)NCBI
Rnor_5.0X121,716,856 - 121,876,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039100612   ⟹   XP_038956540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,912,133 (-)NCBI
mRatBN7.2X113,942,313 - 114,107,151 (-)NCBI
RefSeq Acc Id: XM_063279989   ⟹   XP_063136059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X118,747,298 - 118,825,675 (-)NCBI
RefSeq Acc Id: XP_003752178   ⟸   XM_003752130
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A5N5 (UniProtKB/TrEMBL),   A0A8I5ZU85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257506   ⟸   XM_006257444
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AB93 (UniProtKB/TrEMBL),   A0A8I5ZU85 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018788   ⟸   ENSRNOT00000018788
RefSeq Acc Id: XP_038956540   ⟸   XM_039100612
- Peptide Label: isoform X1
- UniProtKB: F1LM44 (UniProtKB/TrEMBL),   A0A8I6AHM2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088688   ⟸   ENSRNOT00000094168
Ensembl Acc Id: ENSRNOP00000088723   ⟸   ENSRNOT00000094972
Ensembl Acc Id: ENSRNOP00000084359   ⟸   ENSRNOT00000111718
Ensembl Acc Id: ENSRNOP00000082058   ⟸   ENSRNOT00000106563
Ensembl Acc Id: ENSRNOP00000087922   ⟸   ENSRNOT00000114825
Ensembl Acc Id: ENSRNOP00000090232   ⟸   ENSRNOT00000101919
RefSeq Acc Id: NP_001388062   ⟸   NM_001401133
- Peptide Label: isoform c
- UniProtKB: A0A8I6A140 (UniProtKB/TrEMBL),   A6JMD3 (UniProtKB/TrEMBL),   A0A8I5ZU85 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388060   ⟸   NM_001401131
- Peptide Label: isoform a
- UniProtKB: F1LM44 (UniProtKB/TrEMBL),   A0A8I6AHM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001094324   ⟸   NM_001100854
- Peptide Label: isoform c
- UniProtKB: A0A8I6A140 (UniProtKB/TrEMBL),   A6JMD3 (UniProtKB/TrEMBL),   A0A8I5ZU85 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001388061   ⟸   NM_001401132
- Peptide Label: isoform b
- UniProtKB: A0A8I6A901 (UniProtKB/TrEMBL),   A0A8I5ZU85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136059   ⟸   XM_063279989
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZU85 (UniProtKB/TrEMBL)
Protein Domains
BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LM44-F1-model_v2 AlphaFold F1LM44 1-638 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559646 AgrOrtholog
BioCyc Gene G2FUF-1346 BioCyc
Ensembl Genes ENSRNOG00000014029 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018788 ENTREZGENE
  ENSRNOT00000018788.10 UniProtKB/TrEMBL
  ENSRNOT00000094168 ENTREZGENE
  ENSRNOT00000094168.2 UniProtKB/TrEMBL
  ENSRNOT00000094972 ENTREZGENE
  ENSRNOT00000094972.2 UniProtKB/TrEMBL
  ENSRNOT00000101919 ENTREZGENE
  ENSRNOT00000101919.2 UniProtKB/TrEMBL
  ENSRNOT00000106563 ENTREZGENE
  ENSRNOT00000106563.2 UniProtKB/TrEMBL
  ENSRNOT00000111718 ENTREZGENE
  ENSRNOT00000111718.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7462401 IMAGE-MGC_LOAD
InterPro BACK UniProtKB/TrEMBL
  BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Kelch-like_gigaxonin UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
MGC_CLONE MGC:125265 IMAGE-MGC_LOAD
NCBI Gene 313445 ENTREZGENE
PANTHER KELCH-LIKE PROTEIN 13 UniProtKB/TrEMBL
  LD33804P UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  Kelch_KLHDC2_KLHL20_DRC7 UniProtKB/TrEMBL
PhenoGen Klhl13 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014029 RatGTEx
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF117281 UniProtKB/TrEMBL
UniProt A0A8I5ZU85 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A140 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5N5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A901 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHM2 ENTREZGENE
  A6JMD3 ENTREZGENE, UniProtKB/TrEMBL
  F1LM44 ENTREZGENE, UniProtKB/TrEMBL
  Q3MHT7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Klhl13  kelch-like 13 (Drosophila)    kelch-like 13  Name updated 1299863 APPROVED
2006-02-09 Klhl13  kelch-like 13      Symbol and Name status set to provisional 70820 PROVISIONAL