Dctn3l1 (dynactin 3-like 1) - Rat Genome Database

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Gene: Dctn3l1 (dynactin 3-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Dctn3l1
Name: dynactin 3-like 1
RGD ID: 1559475
Description: Predicted to be involved in cytoskeleton-dependent cytokinesis. Predicted to be part of dynactin complex. Orthologous to human DCTN3 (dynactin subunit 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dynactin subunit 3-like; LOC498977; RGD1559475; similar to dynactin 3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817,347,101 - 7,347,898 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl17,341,191 - 7,349,421 (-)EnsemblGRCr8
mRatBN7.215,526,831 - 5,527,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl15,527,048 - 5,527,608 (-)EnsemblmRatBN7.2
Dahl_SR_JrHsd16,846,524 - 6,847,321 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive16,163,999 - 6,164,796 (-)NCBILyon_Normotensive
Lyon_Hypertensive17,330,128 - 7,330,925 (-)NCBILyon_Hypertensive
F344_StmMcwi15,712,699 - 5,713,496 (-)NCBIF344_StmMcwi
Rnor_6.015,238,183 - 5,238,918 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.016,889,380 - 6,889,985 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.415,844,222 - 5,844,782 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera14,050,733 - 4,051,468 (-)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Dctn3l1
4 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
RH127759  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215,526,956 - 5,527,128 (+)MAPPERmRatBN7.2
mRatBN7.2556,881,357 - 56,881,537 (+)MAPPERmRatBN7.2
Rnor_6.0558,098,979 - 58,099,158NCBIRnor6.0
Rnor_6.015,238,249 - 5,238,420NCBIRnor6.0
Rnor_5.0562,623,090 - 62,623,269UniSTSRnor5.0
Rnor_5.016,889,322 - 6,889,493UniSTSRnor5.0
RGSC_v3.415,844,131 - 5,844,302UniSTSRGSC3.4
RGSC_v3.4559,139,697 - 59,139,876UniSTSRGSC3.4
Celera555,475,410 - 55,475,589UniSTS
Celera14,050,799 - 4,050,970UniSTS
Cytogenetic Map1p13UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 10 32 31 69 43 3 39 19 18 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000019345   ⟹   ENSRNOP00000094120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl15,527,048 - 5,527,608 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000152394   ⟹   ENSRNOP00000109937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17,341,191 - 7,349,421 (-)Ensembl
RefSeq Acc Id: NM_001408768   ⟹   NP_001395697
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817,347,101 - 7,347,898 (-)NCBI
mRatBN7.215,526,831 - 5,527,628 (-)NCBI
Dahl_SR_JrHsd16,846,524 - 6,847,321 (-)NCBI
Lyon_Normotensive16,163,999 - 6,164,796 (-)NCBI
Lyon_Hypertensive17,330,128 - 7,330,925 (-)NCBI
F344_StmMcwi15,712,699 - 5,713,496 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001395697 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019561.5
  ENSRNOP00000109937
  ENSRNOP00000109937.1
Ensembl Acc Id: ENSRNOP00000094120   ⟸   ENSRNOT00000019345
RefSeq Acc Id: NP_001395697   ⟸   NM_001408768
- UniProtKB: A0A8I6AIV4 (UniProtKB/TrEMBL),   D4A1B8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109937   ⟸   ENSRNOT00000152394

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559475 AgrOrtholog
BioCyc Gene G2FUF-62407 BioCyc
Ensembl Genes ENSRNOG00000014208 UniProtKB/TrEMBL
  ENSRNOG00000014431 Ensembl
  ENSRNOG00000081039 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019561.7 UniProtKB/TrEMBL
  ENSRNOT00000152394 ENTREZGENE
  ENSRNOT00000152394.1 UniProtKB/TrEMBL
InterPro DCTN3 UniProtKB/TrEMBL
NCBI Gene 498977 ENTREZGENE
PANTHER DYNACTIN SUBUNIT 3 UniProtKB/TrEMBL
  PTHR28360 UniProtKB/TrEMBL
Pfam Dynactin_p22 UniProtKB/TrEMBL
PhenoGen Dctn3l1 PhenoGen
RatGTEx ENSRNOG00000014208 RatGTEx
  ENSRNOG00000014431 RatGTEx
  ENSRNOG00000081039 RatGTEx
UniProt A0A8I6AIV4 ENTREZGENE
  A0ABK0LUS4_RAT UniProtKB/TrEMBL
  D4A1B8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Dctn3l1  dynactin 3-like 1  RGD1559475  similar to dynactin 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1559475  similar to dynactin 3   RGD1559475_predicted  similar to dynactin 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559475_predicted  similar to dynactin 3 (predicted)  LOC498977  similar to dynactin 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498977  similar to dynactin 3      Symbol and Name status set to provisional 70820 PROVISIONAL