Purb (purine rich element binding protein B) - Rat Genome Database

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Gene: Purb (purine rich element binding protein B) Rattus norvegicus
Analyze
Symbol: Purb
Name: purine rich element binding protein B
RGD ID: 1559465
Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; mRNA regulatory element binding translation repressor activity; and purine-rich negative regulatory element binding activity. Involved in negative regulation of transcription by RNA polymerase II. Is active in nucleus. Orthologous to human PURB (purine rich element binding protein B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: pur-beta; purine-rich element-binding protein B; transcription factor Pur-beta; transcriptional activator protein Pur-beta; transcriptional regulator protein Pur-beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,556,296 - 85,558,779 (-)NCBIGRCr8
mRatBN7.21481,342,374 - 81,344,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,336,448 - 81,351,432 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,743,668 - 85,746,151 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,983,466 - 86,985,949 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,433,062 - 83,435,545 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,736,876 - 86,739,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,736,878 - 86,739,335 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,371,417 - 80,373,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,230,346 - 87,232,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1480,223,695 - 80,226,154 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbRatpleomorphic xanthoastrocytoma  ISOPURB (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358

1 to 20 of 81 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbRat1,2-dichloroethane decreases expressionISOPurb (Mus musculus)6480464ethylene dichloride results in decreased expression of PURB mRNACTDPMID:28960355
PurbRat1,2-dimethylhydrazine multiple interactionsISOPurb (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PURB mRNA]CTDPMID:22206623
PurbRat1,2-dimethylhydrazine increases expressionISOPurb (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PURB mRNACTDPMID:22206623
PurbRat17alpha-ethynylestradiol increases expressionISOPurb (Mus musculus)6480464Ethinyl Estradiol results in increased expression of PURB mRNACTDPMID:17942748
PurbRat17alpha-ethynylestradiol multiple interactionsISOPurb (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PURB mRNACTDPMID:17942748
PurbRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPurb (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of PURB mRNACTDPMID:24058054
PurbRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PURB mRNACTDPMID:34747641
PurbRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPurb (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PURB mRNACTDPMID:21570461
PurbRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPurb (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PURB mRNACTDPMID:17942748
PurbRat4,4'-sulfonyldiphenol affects expressionISOPurb (Mus musculus)6480464bisphenol S affects the expression of PURB mRNACTDPMID:39298647
PurbRat4,4'-sulfonyldiphenol affects methylationISOPurb (Mus musculus)6480464bisphenol S affects the methylation of PURB geneCTDPMID:31683443
PurbRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PURB mRNACTDPMID:30047161
PurbRataflatoxin B1 increases expressionISOPurb (Mus musculus)6480464Aflatoxin B1 results in increased expression of PURB mRNACTDPMID:19770486
PurbRatall-trans-retinoic acid increases expressionISOPurb (Mus musculus)6480464Tretinoin results in increased expression of PURB mRNACTDPMID:16788091
PurbRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of PURB mRNACTDPMID:30047161
PurbRatantirheumatic drug decreases expressionISOPURB (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of PURB mRNACTDPMID:24449571
PurbRatAroclor 1254 decreases expressionISOPurb (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of PURB mRNACTDPMID:23650126
PurbRatatrazine increases expressionISOPURB (Homo sapiens)6480464Atrazine results in increased expression of PURB mRNACTDPMID:22378314
PurbRatbenzene increases expressionISOPURB (Homo sapiens)6480464Benzene results in increased expression of PURB mRNACTDPMID:15929907
PurbRatbenzo[a]pyrene increases expressionISOPurb (Mus musculus)6480464Benzo(a)pyrene results in increased expression of PURB mRNACTDPMID:20504355 and PMID:22228805

1 to 20 of 81 rows

Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbRatnegative regulation of DNA-templated transcription acts_upstream_of_or_withinIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatnegative regulation of DNA-templated transcription acts_upstream_of_or_withinISOPurb (Mus musculus)1624291 PMID:15282343RGDPMID:15282343
PurbRatnegative regulation of transcription by RNA polymerase II involved_inIDA 1581942PMID:12933792HGNC-UCL 
PurbRatnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOPurb (Mus musculus)1624291MGI:3705267 PMID:23723417RGDPMID:23723417
PurbRatnegative regulation of transcription by RNA polymerase II involved_inISOPurb (Mus musculus)1624291 PMID:15282343RGDPMID:15282343
PurbRatnegative regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatnegative regulation of translation involved_inIEAGO:00009001600115GO_REF:0000108GOCGO_REF:0000108
PurbRatpositive regulation of transcription by RNA polymerase II involved_inISOPurb (Mus musculus)1624291 PMID:31918924RGDPMID:31918924
PurbRatpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatpositive regulation of transcription by RNA polymerase II involved_inISSUniProtKB:O352951600115GO_REF:0000024UniProtGO_REF:0000024
PurbRatregulation of transcription by RNA polymerase II involved_inIBAMGI:103079 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PurbRattranslation involved_inIEAInterPro:IPR001380 and InterPro:IPR0182561600115GO_REF:0000002InterProGO_REF:0000002
1 to 12 of 12 rows

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbRatcytosolic large ribosomal subunit part_ofIBAMGI:105922 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PurbRatnucleoplasm located_inIEAUniProtKB:Q96QR8 and ensembl:ENSP000003790511600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatnucleoplasm located_inISOPURB (Homo sapiens)1624291 RGDGO_REF:0000052
PurbRatnucleus is_active_inIDA 1581942PMID:12933792HGNC-UCL 
PurbRatnucleus located_inIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatnucleus located_inISOPurb (Mus musculus)1624291 PMID:15282343 and PMID:33743134RGDPMID:15282343 and PMID:33743134
PurbRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
PurbRatnucleus is_active_inIBAFB:FBgn0022361 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PurbRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
PurbRatribonucleoprotein complex part_ofIEAUniProtKB-KW:KW-06871600115GO_REF:0000043UniProtGO_REF:0000043
PurbRatribosome located_inIEAInterPro:IPR001380 and InterPro:IPR0182561600115GO_REF:0000002InterProGO_REF:0000002
PurbRatribosome located_inIEAUniProtKB-KW:KW-06891600115GO_REF:0000043UniProtGO_REF:0000043
1 to 12 of 12 rows

Molecular Function
1 to 20 of 36 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PurbRatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
PurbRatDNA-binding transcription factor activity enablesISOPurb (Mus musculus)1624291 PMID:15282343RGDPMID:15282343
PurbRatDNA-binding transcription factor activity enablesIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIBAMGI:103079 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
PurbRatDNA-binding transcription factor binding enablesISSUniProtKB:O352951600115GO_REF:0000024UniProtGO_REF:0000024
PurbRatDNA-binding transcription factor binding enablesIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatDNA-binding transcription factor binding enablesISOPurb (Mus musculus)1624291UniProtKB:P42669 and PMID:10318844RGDPMID:10318844
PurbRatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIDA 1581942PMID:12933792HGNC-UCL 
PurbRatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISOPurb (Mus musculus)1624291 PMID:15282343 more ...RGDPMID:15282343 more ...
PurbRatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISSUniProtKB:O352951600115GO_REF:0000024UniProtGO_REF:0000024
PurbRatDNA-binding transcription repressor activity, RNA polymerase II-specific enablesIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatdouble-stranded DNA binding enablesISOPurb (Mus musculus)1624291 PMID:15282343RGDPMID:15282343
PurbRatdouble-stranded DNA binding enablesIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatmRNA binding enablesIEAUniProtKB:O35295 and ensembl:ENSMUSP000001369571600115GO_REF:0000107EnsemblGO_REF:0000107
PurbRatmRNA binding enablesISOPurb (Mus musculus)1624291 PMID:12933792RGDPMID:12933792
PurbRatmRNA binding enablesISSUniProtKB:O352951600115GO_REF:0000024UniProtGO_REF:0000024
PurbRatmRNA regulatory element binding translation repressor activity enablesIDA 1581942PMID:12933792HGNC-UCL 
PurbRatprotein binding enablesISOPURB (Homo sapiens)1624291UniProtKB:Q6ZNH5 more ...RGDPMID:32296183
PurbRatprotein binding enablesISOPurb (Mus musculus)1624291PR:O89090 more ...RGDPMID:15282343 more ...
PurbRatpurine-rich negative regulatory element binding enablesIDA 1581942PMID:12933792HGNC-UCL 
1 to 20 of 36 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure. Gupta M, etal., J Biol Chem. 2003 Nov 7;278(45):44935-48. Epub 2003 Aug 21.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9334258   PMID:10318844   PMID:11032866   PMID:15282343   PMID:16309856   PMID:16376299   PMID:21700703   PMID:22658674   PMID:22681889   PMID:23723417   PMID:25002582   PMID:25931508  
PMID:29476059   PMID:33450132  



Purb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,556,296 - 85,558,779 (-)NCBIGRCr8
mRatBN7.21481,342,374 - 81,344,857 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,336,448 - 81,351,432 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,743,668 - 85,746,151 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,983,466 - 86,985,949 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,433,062 - 83,435,545 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,736,876 - 86,739,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,736,878 - 86,739,335 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,371,417 - 80,373,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,230,346 - 87,232,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1480,223,695 - 80,226,154 (-)NCBICelera
Cytogenetic Map14q21NCBI
PURB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,876,299 - 44,885,530 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,876,299 - 44,885,530 (-)EnsemblGRCh38hg38GRCh38
GRCh37744,915,898 - 44,925,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,882,417 - 44,891,485 (-)NCBINCBI36Build 36hg18NCBI36
Build 34744,689,133 - 44,698,200NCBI
Celera745,014,669 - 45,023,741 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,801,230 - 44,810,302 (-)NCBIHuRef
CHM1_1744,920,237 - 44,929,309 (-)NCBICHM1_1
T2T-CHM13v2.0745,036,709 - 45,045,943 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,955,325 - 44,964,397 (-)NCBI
Purb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,417,599 - 6,426,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,417,599 - 6,425,917 (-)EnsemblGRCm39 Ensembl
GRCm38116,467,599 - 6,476,076 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,467,599 - 6,475,917 (-)EnsemblGRCm38mm10GRCm38
MGSCv37116,374,776 - 6,375,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,374,776 - 6,375,920 (-)NCBIMGSCv36mm8
Celera116,960,150 - 6,961,293 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.16NCBI
Purb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554567,322,973 - 7,323,529 (+)NCBIChiLan1.0ChiLan1.0
PURB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,789,512 - 49,802,328 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,114,250 - 98,127,055 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,590,183 - 45,600,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,659,121 - 45,673,991 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,667,233 - 45,668,159 (-)Ensemblpanpan1.1panPan2
PURB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,512,329 - 2,520,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,340,299 - 14,348,729 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.01613,973,590 - 13,982,018 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01613,952,878 - 13,961,316 (+)NCBIUU_Cfam_GSD_1.0
Purb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,526,521 - 100,551,530 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647819,738,252 - 19,747,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PURB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,510,182 - 50,511,108 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,510,010 - 50,518,965 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,333,599 - 55,342,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PURB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,796,087 - 13,805,162 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,796,118 - 13,797,056 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,731,839 - 8,741,238 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Purb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,398,481 - 7,399,434 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,398,481 - 7,406,923 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Purb
9 total Variants

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:41
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000009214
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 23 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat

1 to 10 of 23 rows
SGC32761  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,342,422 - 81,342,548 (+)MAPPERmRatBN7.2
Rnor_6.01486,736,901 - 86,737,026NCBIRnor6.0
Rnor_5.01480,371,442 - 80,371,567UniSTSRnor5.0
RGSC_v3.41487,230,371 - 87,230,496UniSTSRGSC3.4
Celera1480,223,720 - 80,223,845UniSTS
Cytogenetic Map14q21UniSTS
AA859841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,343,936 - 81,344,135 (+)MAPPERmRatBN7.2
Rnor_6.01486,738,415 - 86,738,613NCBIRnor6.0
Rnor_5.01480,372,956 - 80,373,154UniSTSRnor5.0
RGSC_v3.41487,231,885 - 87,232,083UniSTSRGSC3.4
Celera1480,225,234 - 80,225,432UniSTS
RH 3.4 Map14579.0UniSTS
Cytogenetic Map14q21UniSTS
BI284455  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81485,556,803 - 85,556,970 (+)Marker Load Pipeline
mRatBN7.21481,342,881 - 81,343,048 (+)MAPPERmRatBN7.2
Rnor_6.01486,737,360 - 86,737,526NCBIRnor6.0
Rnor_5.01480,371,901 - 80,372,067UniSTSRnor5.0
RGSC_v3.41487,230,830 - 87,230,996UniSTSRGSC3.4
Celera1480,224,179 - 80,224,345UniSTS
RH 3.4 Map14586.6UniSTS
Cytogenetic Map14q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000078282   ⟹   ENSRNOP00000069267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1486,736,878 - 86,739,335 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096069   ⟹   ENSRNOP00000083797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1481,336,448 - 81,351,432 (-)Ensembl
RefSeq Acc Id: NM_001017503   ⟹   NP_001017503
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81485,556,296 - 85,558,779 (-)NCBI
mRatBN7.21481,342,374 - 81,344,857 (-)NCBI
Rnor_6.01486,736,876 - 86,739,335 (-)NCBI
Rnor_5.01480,371,417 - 80,373,876 (-)NCBI
RGSC_v3.41487,230,346 - 87,232,805 (-)RGD
Celera1480,223,695 - 80,226,154 (-)RGD
Sequence:
Protein RefSeqs NP_001017503 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD38899 (Get FASTA)   NCBI Sequence Viewer  
  EDM00360 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079672
GenBank Protein Q68A21 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001017503   ⟸   NM_001017503
- UniProtKB: A0A8I5ZZX6 (UniProtKB/TrEMBL),   A6IKU6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069267   ⟸   ENSRNOT00000078282
Ensembl Acc Id: ENSRNOP00000083797   ⟸   ENSRNOT00000096069

Name Modeler Protein Id AA Range Protein Structure
AF-Q68A21-F1-model_v2 AlphaFold Q68A21 1-315 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-15085 BioCyc
Ensembl Genes ENSRNOG00000056150 Ensembl
  ENSRNOG00000062895 ENTREZGENE
  ENSRNOG00000069265 Ensembl
Ensembl Transcript ENSRNOT00000106653 ENTREZGENE
Gene3D-CATH 3.10.450.700 UniProtKB/Swiss-Prot
  3.30.2450.30 UniProtKB/Swiss-Prot
InterPro PUR-bd_fam UniProtKB/Swiss-Prot
KEGG Report rno:498407 UniProtKB/Swiss-Prot
NCBI Gene 498407 ENTREZGENE
PANTHER PTHR12611 UniProtKB/Swiss-Prot
  PTHR12611:SF4 UniProtKB/Swiss-Prot
Pfam PurA UniProtKB/Swiss-Prot
PhenoGen Purb PhenoGen
RatGTEx ENSRNOG00000056150 RatGTEx
  ENSRNOG00000062895 RatGTEx
  ENSRNOG00000069265 RatGTEx
SMART PUR UniProtKB/Swiss-Prot
UniProt A0A8I5ZNK4_RAT UniProtKB/TrEMBL
  A0A8I5ZZX6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKU6 ENTREZGENE, UniProtKB/TrEMBL
  PURB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Purb  purine rich element binding protein B  pur-beta  transcription factor Pur-beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 pur-beta  transcription factor Pur-beta      Symbol and Name status set to provisional 70820 PROVISIONAL