Cadps2 (calcium dependent secretion activator 2) - Rat Genome Database

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Gene: Cadps2 (calcium dependent secretion activator 2) Rattus norvegicus
Analyze
Symbol: Cadps2
Name: calcium dependent secretion activator 2
RGD ID: 1559440
Description: Predicted to enable lipid binding activity and metal ion binding activity. Predicted to be involved in exocytosis and positive regulation of exocytosis. Predicted to act upstream of or within cellular response to starvation; hematopoietic stem cell homeostasis; and synaptic vesicle priming. Predicted to be located in cytoplasmic vesicle; microtubule organizing center; and synaptic membrane. Predicted to be active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynapse. Orthologous to human CADPS2 (calcium dependent secretion activator 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ca++-dependent secretion activator 2; Ca2+ dependent secretion activator 2; Ca2+-dependent activator protein for secretion 2; calcium-dependent secretion activator 2; LOC312166; RGD1559440; similar to Ca2+-dependent activator for secretion protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8452,746,054 - 53,275,252 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl452,746,065 - 53,275,004 (-)EnsemblGRCr8
mRatBN7.2451,780,415 - 52,309,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)EnsemblmRatBN7.2
Rnor_6.0450,326,447 - 50,861,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl450,326,442 - 50,860,756 (-)Ensemblrn6Rnor6.0
Rnor_5.0450,109,220 - 50,640,613 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4449,658,535 - 50,206,014 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera446,974,764 - 47,500,739 (-)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP)
aristolochic acid A  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
etoposide  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
glyphosate  (EXP)
GW 4064  (ISO)
inulin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (ISO)
O-methyleugenol  (ISO)
omeprazole  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14715936   PMID:15932944   PMID:21040848   PMID:23260145   PMID:25374362   PMID:25437547  


Genomics

Comparative Map Data
Cadps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8452,746,054 - 53,275,252 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl452,746,065 - 53,275,004 (-)EnsemblGRCr8
mRatBN7.2451,780,415 - 52,309,641 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)EnsemblmRatBN7.2
Rnor_6.0450,326,447 - 50,861,161 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl450,326,442 - 50,860,756 (-)Ensemblrn6Rnor6.0
Rnor_5.0450,109,220 - 50,640,613 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4449,658,535 - 50,206,014 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera446,974,764 - 47,500,739 (-)NCBICelera
Cytogenetic Map4q22NCBI
CADPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387122,318,411 - 122,886,460 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7122,318,411 - 122,886,779 (-)Ensemblhg38GRCh38
GRCh377121,958,465 - 122,526,514 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367121,745,714 - 122,313,790 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347121,553,403 - 122,120,465NCBI
Celera7116,762,799 - 117,331,572 (-)NCBICelera
Cytogenetic Map7q31.32NCBI
HuRef7116,321,864 - 116,889,045 (-)NCBIHuRef
CHM1_17121,891,856 - 122,459,852 (-)NCBICHM1_1
T2T-CHM13v2.07123,634,402 - 124,203,026 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27121,353,164 - 121,915,693 (-)NCBI
Cadps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39623,262,765 - 23,840,662 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl623,262,772 - 23,839,420 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38623,262,773 - 23,841,175 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl623,262,773 - 23,839,421 (-)Ensemblmm10GRCm38
MGSCv37623,212,838 - 23,789,300 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36623,212,839 - 23,789,139 (-)NCBIMGSCv36mm8
Celera623,306,392 - 23,862,052 (-)NCBICelera
Cytogenetic Map6A3.1NCBI
cM Map610.57NCBI
Cadps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554793,961,731 - 4,485,710 (-)Ensembl
ChiLan1.0NW_0049554793,961,877 - 4,485,710 (-)NCBIChiLan1.0ChiLan1.0
CADPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26159,190,582 - 159,757,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1711,200,836 - 11,767,539 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07114,328,933 - 114,896,388 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17127,013,043 - 127,579,665 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7127,014,772 - 127,579,249 (-)EnsemblpanPan2panpan1.1
CADPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11460,109,253 - 60,465,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1460,107,538 - 60,556,817 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1459,530,071 - 59,982,436 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01460,148,277 - 60,601,897 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1460,146,547 - 60,602,286 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11460,238,319 - 60,691,363 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01459,866,769 - 60,319,711 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01460,244,197 - 60,696,999 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cadps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511849,191,231 - 49,699,089 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366052,505,231 - 3,011,468 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366052,505,064 - 3,012,322 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CADPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1824,372,544 - 24,867,482 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11824,372,547 - 24,867,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21825,969,731 - 26,464,337 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CADPS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12191,117,749 - 91,669,284 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604211,821,174 - 12,425,811 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cadps2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478313,142,198 - 13,700,683 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478313,142,036 - 13,701,430 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cadps2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16115,451,604 - 115,977,172 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cadps2
2650 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:448
Count of miRNA genes:177
Interacting mature miRNAs:196
Transcripts:ENSRNOT00000010537, ENSRNOT00000064206, ENSRNOT00000065088, ENSRNOT00000067030, ENSRNOT00000068404, ENSRNOT00000072896, ENSRNOT00000074651
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)41308014658080146Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)44049044275726188Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
10450825Scl78Serum cholesterol level QTL 783.70.01blood VLDL cholesterol amount (VT:0005144)blood low density lipoprotein cholesterol level (CMO:0000053)45014392658080146Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
10450821Scl77Serum cholesterol level QTL 774.10.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)45014392658080146Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
10450818Scl76Serum cholesterol level QTL 763.60.01blood VLDL cholesterol amount (VT:0005144)blood high density lipoprotein cholesterol level (CMO:0000052)45014392658080146Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)44047145375939996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43353881653719714Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat

Markers in Region
AW550108  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2451,780,690 - 51,780,826 (+)MAPPERmRatBN7.2
Rnor_6.0450,326,719 - 50,326,854NCBIRnor6.0
Rnor_5.0450,109,487 - 50,109,622UniSTSRnor5.0
RGSC_v3.4449,658,806 - 49,658,941UniSTSRGSC3.4
Celera446,975,036 - 46,975,171UniSTS
Cytogenetic Map4q22UniSTS
GDB:1317954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2451,955,795 - 51,955,941 (+)MAPPERmRatBN7.2
Rnor_6.0450,503,086 - 50,503,231NCBIRnor6.0
Rnor_5.0450,283,907 - 50,284,052UniSTSRnor5.0
RGSC_v3.4449,835,751 - 49,835,896UniSTSRGSC3.4
Celera447,150,413 - 47,150,558UniSTS
Cytogenetic Map4q22UniSTS
RH137681  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2451,943,397 - 51,943,518 (+)MAPPERmRatBN7.2
Rnor_6.0450,490,204 - 50,490,324NCBIRnor6.0
Rnor_5.0450,271,025 - 50,271,145UniSTSRnor5.0
RGSC_v3.4449,823,353 - 49,823,473UniSTSRGSC3.4
Celera447,138,016 - 47,138,136UniSTS
RH 3.4 Map4297.1UniSTS
Cytogenetic Map4q22UniSTS
PMC126259P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2451,780,477 - 51,780,600 (+)MAPPERmRatBN7.2
Rnor_6.0450,326,506 - 50,326,628NCBIRnor6.0
Rnor_5.0450,109,274 - 50,109,396UniSTSRnor5.0
RGSC_v3.4449,658,593 - 49,658,715UniSTSRGSC3.4
Celera446,974,823 - 46,974,945UniSTS
Cytogenetic Map4q22UniSTS
BE119864  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2451,798,315 - 51,798,508 (+)MAPPERmRatBN7.2
Rnor_6.0450,344,342 - 50,344,534NCBIRnor6.0
Rnor_5.0450,127,110 - 50,127,302UniSTSRnor5.0
RGSC_v3.4449,676,430 - 49,676,622UniSTSRGSC3.4
Celera446,992,657 - 46,992,849UniSTS
RH 3.4 Map4297.3UniSTS
Cytogenetic Map4q22UniSTS
AU049560  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8453,228,497 - 53,228,782 (+)Marker Load Pipeline
mRatBN7.2452,262,878 - 52,263,163 (+)MAPPERmRatBN7.2
Rnor_6.0450,804,890 - 50,805,174NCBIRnor6.0
Rnor_5.0450,584,618 - 50,584,902UniSTSRnor5.0
RGSC_v3.4450,159,492 - 50,159,776UniSTSRGSC3.4
Celera447,454,133 - 47,454,417UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 81 59 6 345 181 11 140 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001060172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002726331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_002729291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003753870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000068404   ⟹   ENSRNOP00000060154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,274,880 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,264 (-)Ensembl
Rnor_6.0 Ensembl450,326,442 - 50,860,756 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108432   ⟹   ENSRNOP00000097144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114656   ⟹   ENSRNOP00000077369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114880   ⟹   ENSRNOP00000092324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117045   ⟹   ENSRNOP00000085438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119022   ⟹   ENSRNOP00000080739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,652 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119282   ⟹   ENSRNOP00000077855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
mRatBN7.2 Ensembl451,781,053 - 52,309,829 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129904   ⟹   ENSRNOP00000110636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000162644   ⟹   ENSRNOP00000106296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl452,746,065 - 53,275,004 (-)Ensembl
RefSeq Acc Id: NM_001427791   ⟹   NP_001414720
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,065 - 53,275,004 (-)NCBI
RefSeq Acc Id: XM_002729291   ⟹   XP_002729337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
mRatBN7.2451,780,415 - 52,309,641 (-)NCBI
Rnor_6.0450,326,447 - 50,861,161 (-)NCBI
Rnor_5.0450,109,220 - 50,640,613 (-)NCBI
RGSC_v3.4449,658,535 - 50,206,014 (-)RGD
Sequence:
RefSeq Acc Id: XM_039108612   ⟹   XP_038964540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,249 (-)NCBI
mRatBN7.2451,781,174 - 52,309,264 (-)NCBI
RefSeq Acc Id: XM_039108614   ⟹   XP_038964542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
mRatBN7.2451,781,174 - 52,309,264 (-)NCBI
RefSeq Acc Id: XM_063285973   ⟹   XP_063142043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
RefSeq Acc Id: XM_063285974   ⟹   XP_063142044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,249 (-)NCBI
RefSeq Acc Id: XM_063285975   ⟹   XP_063142045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
RefSeq Acc Id: XM_063285976   ⟹   XP_063142046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,251 (-)NCBI
RefSeq Acc Id: XM_063285977   ⟹   XP_063142047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
RefSeq Acc Id: XM_063285978   ⟹   XP_063142048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,757,184 - 53,275,252 (-)NCBI
RefSeq Acc Id: XM_063285979   ⟹   XP_063142049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8452,746,054 - 53,275,250 (-)NCBI
RefSeq Acc Id: XP_002729337   ⟸   XM_002729291
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZKA3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060154   ⟸   ENSRNOT00000068404
RefSeq Acc Id: XP_038964542   ⟸   XM_039108614
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZKA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964540   ⟸   XM_039108612
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZKA3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077855   ⟸   ENSRNOT00000119282
Ensembl Acc Id: ENSRNOP00000080739   ⟸   ENSRNOT00000119022
Ensembl Acc Id: ENSRNOP00000097144   ⟸   ENSRNOT00000108432
Ensembl Acc Id: ENSRNOP00000092324   ⟸   ENSRNOT00000114880
Ensembl Acc Id: ENSRNOP00000085438   ⟸   ENSRNOT00000117045
Ensembl Acc Id: ENSRNOP00000077369   ⟸   ENSRNOT00000114656
RefSeq Acc Id: XP_063142046   ⟸   XM_063285976
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ASE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142049   ⟸   XM_063285979
- Peptide Label: isoform X10
- UniProtKB: A0A8I5Y244 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142045   ⟸   XM_063285975
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AHC2 (UniProtKB/TrEMBL),   A0A8I5Y244 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142047   ⟸   XM_063285977
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZKA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142043   ⟸   XM_063285973
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ASE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142044   ⟸   XM_063285974
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GDI0 (UniProtKB/TrEMBL),   A6IE75 (UniProtKB/TrEMBL),   A0A8I6ASE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414720   ⟸   NM_001427791
- UniProtKB: A0A8I6ASE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142048   ⟸   XM_063285978
- Peptide Label: isoform X9
- UniProtKB: A0A8I6ASE4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110636   ⟸   ENSRNOT00000129904
Ensembl Acc Id: ENSRNOP00000106296   ⟸   ENSRNOT00000162644
Protein Domains
C2   MHD1   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LWT1-F1-model_v2 AlphaFold F1LWT1 1-1197 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559440 AgrOrtholog
BioCyc Gene G2FUF-45496 BioCyc
Ensembl Genes ENSRNOG00000007636 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068404.6 UniProtKB/TrEMBL
  ENSRNOT00000108432 ENTREZGENE
  ENSRNOT00000108432.2 UniProtKB/TrEMBL
  ENSRNOT00000114656.2 UniProtKB/TrEMBL
  ENSRNOT00000114880.2 UniProtKB/TrEMBL
  ENSRNOT00000117045 ENTREZGENE
  ENSRNOT00000117045.2 UniProtKB/TrEMBL
  ENSRNOT00000119022 ENTREZGENE
  ENSRNOT00000119022.2 UniProtKB/TrEMBL
  ENSRNOT00000119282 ENTREZGENE
  ENSRNOT00000119282.2 UniProtKB/TrEMBL
  ENSRNOT00000129904.1 UniProtKB/TrEMBL
  ENSRNOT00000162644.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  Ca-dep_secretion_activator UniProtKB/TrEMBL
  CAPS UniProtKB/TrEMBL
  CAPS_C2 UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
NCBI Gene 312166 ENTREZGENE
PANTHER CALCIUM-DEPENDENT SECRETION ACTIVATOR 2 UniProtKB/TrEMBL
  PTHR12166 UniProtKB/TrEMBL
Pfam C2_CAPS UniProtKB/TrEMBL
  DUF1041 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Cadps2 PhenoGen
PROSITE MHD1 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007636 RatGTEx
SMART DUF1041 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5Y244 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKA3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRH8_RAT UniProtKB/TrEMBL
  A0A8I6AHC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GDI0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L7W1_RAT UniProtKB/TrEMBL
  A0ABK0M5E5_RAT UniProtKB/TrEMBL
  A6IE75 ENTREZGENE, UniProtKB/TrEMBL
  F1LWT1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Cadps2  calcium dependent secretion activator 2  Cadps2  Ca2+ dependent secretion activator 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Cadps2  Ca2+ dependent secretion activator 2  Cadps2  Ca++-dependent secretion activator 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Cadps2  Ca++-dependent secretion activator 2  Cadps2  Ca2+-dependent activator protein for secretion 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Cadps2  Ca2+-dependent activator protein for secretion 2  RGD1559440_predicted  similar to Ca2+-dependent activator for secretion protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1559440_predicted  similar to Ca2+-dependent activator for secretion protein 2 (predicted)  LOC312166  similar to Ca2+-dependent activator for secretion protein 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC312166  similar to Ca2+-dependent activator for secretion protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL