Advanced Search (OLGA)

Gene: Wwc2 (WW and C2 domain containing 2) Rattus norvegicus

Analyze

Symbol:

Wwc2

Name:

WW and C2 domain containing 2

RGD ID:

1559427

Description:

Predicted to enable kinase binding activity and signaling adaptor activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; negative regulation of organ growth; and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within hippo signaling. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human WWC2 (WW and C2 domain containing 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC498630; RGD1559427; similar to BH3-only member B protein; WW, C2 and coiled-coil domain containing 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WWC2 (WW and C2 domain containing 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Wwc2 (WW, C2 and coiled-coil domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Wwc2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WWC2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WWC2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wwc2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WWC2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	WWC2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wwc2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Wwc2 (WW and C2 domain containing 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	WWC2 (WW and C2 domain containing 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Wwc2 (WW, C2 and coiled-coil domain containing 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	kibra	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	kibra	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	wwc2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	50,991,096 - 51,154,529 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	50,991,096 - 51,154,526 (+)	Ensembl				GRCr8
mRatBN7.2	16	44,258,372 - 44,421,815 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	44,258,372 - 44,421,812 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	49,663,863 - 49,828,168 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	53,024,440 - 53,188,739 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	48,300,572 - 48,465,778 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	47,368,768 - 47,533,816 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	47,368,768 - 47,533,816 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	47,091,900 - 47,254,470 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	47,456,709 - 47,624,245 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	42,271,804 - 42,433,958 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

long QT syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

biochanin A (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clobetasol (ISO)

clodronic acid (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

diuron (EXP)

endosulfan (EXP)

ethanol (ISO)

fenofibrate (EXP)

fenthion (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

gentamycin (EXP)

GSK-J4 (ISO)

ifosfamide (ISO)

indole-3-methanol (EXP)

metformin (EXP)

methamphetamine (ISO)

methimazole (EXP)

methoxychlor (EXP)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

ozone (ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (EXP)

phenobarbital (ISO)

quercetin (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (EXP,ISO)

troglitazone (EXP,ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (IBA)

hippo signaling (IEA,ISO)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of hippo signaling (IEA,ISO)

negative regulation of organ growth (IBA,IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IBA)

regulation of hippo signaling (IBA)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO)

Molecular Function

kinase binding (IBA,IEA,ISO)

molecular adaptor activity (IBA,IEA,ISO)

protein binding (ISO)

signaling adaptor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:24682284

Genomics

Comparative Map Data

Wwc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	50,991,096 - 51,154,529 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	50,991,096 - 51,154,526 (+)	Ensembl				GRCr8
mRatBN7.2	16	44,258,372 - 44,421,815 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	44,258,372 - 44,421,812 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	49,663,863 - 49,828,168 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	53,024,440 - 53,188,739 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	48,300,572 - 48,465,778 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	47,368,768 - 47,533,816 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	47,368,768 - 47,533,816 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	47,091,900 - 47,254,470 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	47,456,709 - 47,624,245 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	42,271,804 - 42,433,958 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

WWC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	183,099,257 - 183,320,777 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	183,099,126 - 183,320,777 (+)	Ensembl			hg38	GRCh38
GRCh37	4	184,020,410 - 184,241,930 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	184,257,457 - 184,478,924 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	4	181,354,474 - 181,575,877 (+)	NCBI		Celera
Cytogenetic Map	4	q35.1	NCBI
HuRef	4	179,780,892 - 180,002,267 (+)	NCBI		HuRef
CHM1_1	4	183,996,866 - 184,218,376 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	186,442,799 - 186,664,233 (+)	NCBI		T2T-CHM13v2.0

Wwc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	48,279,117 - 48,443,579 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	48,276,994 - 48,443,959 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	47,826,082 - 47,990,544 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	47,823,959 - 47,990,924 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	48,912,949 - 49,075,905 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	49,326,412 - 49,489,368 (-)	NCBI		MGSCv36	mm8
Celera	8	50,505,747 - 50,669,369 (-)	NCBI		Celera
Cytogenetic Map	8	B1.1	NCBI
cM Map	8	26.91	NCBI

Wwc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	25,482,601 - 25,627,580 (-)	Ensembl
ChiLan1.0	NW_004955403	25,482,601 - 25,602,412 (-)	NCBI	ChiLan1.0	ChiLan1.0

WWC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	180,835,775 - 181,050,865 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	181,196,720 - 181,415,840 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	175,280,079 - 175,495,156 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	187,597,081 - 187,721,702 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	187,597,081 - 187,721,702 (+)	Ensembl			panPan2	panpan1.1

WWC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	47,014,151 - 47,185,456 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	47,013,943 - 47,185,500 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	47,447,206 - 47,652,095 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	49,237,790 - 49,443,012 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	49,237,582 - 49,443,483 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	47,199,477 - 47,404,477 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	47,813,883 - 48,019,107 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	47,954,522 - 48,159,690 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Wwc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	32,242,691 - 32,360,134 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936554	5,752,038 - 5,899,089 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936554	5,749,850 - 5,852,874 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WWC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	44,615,983 - 44,802,786 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	44,615,731 - 44,802,717 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	51,228,437 - 51,415,435 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WWC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	129,074,640 - 129,293,372 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	129,074,847 - 129,290,392 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	109,289,423 - 109,509,168 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wwc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	13,829,415 - 14,053,067 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624769	13,829,319 - 14,058,053 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Wwc2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	40,044,361 - 40,204,959 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Wwc2
482 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	823
Count of miRNA genes:	331
Interacting mature miRNAs:	434
Transcripts:	ENSRNOT00000017966
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	44455123	89455123	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	36928782	81928782	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	41992064	86992064	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	28468701	73468701	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	49099196	91442908	Rat
1357403	Slep4	Serum leptin concentration QTL 4	3.91		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	32361043	77361043	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
631833	Sach2	Saccharin preference QTL 2	4	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake rate (CMO:0001613)	16	49757666	56898388	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	31058039	76058039	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	34398294	79398294	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	31885271	76885271	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	44455123	89455123	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	15905802	60905802	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat

Markers in Region

BF410396

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	44,421,233 - 44,421,473 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	47,533,238 - 47,533,477	NCBI	Rnor6.0
Rnor_5.0	16	47,253,892 - 47,254,131	UniSTS	Rnor5.0
RGSC_v3.4	16	47,623,667 - 47,623,906	UniSTS	RGSC3.4
Celera	16	42,433,380 - 42,433,619	UniSTS
Cytogenetic Map	16	q11	UniSTS

BE107847

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	44,414,014 - 44,414,168 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	47,525,812 - 47,525,965	NCBI	Rnor6.0
Rnor_5.0	16	47,246,466 - 47,246,619	UniSTS	Rnor5.0
RGSC_v3.4	16	47,616,448 - 47,616,601	UniSTS	RGSC3.4
Celera	16	42,426,161 - 42,426,314	UniSTS
RH 3.4 Map	16	438.5	UniSTS
Cytogenetic Map	16	q11	UniSTS

BF390151

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	44,273,447 - 44,273,610 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	47,384,163 - 47,384,325	NCBI	Rnor6.0
Rnor_5.0	16	47,106,397 - 47,106,559	UniSTS	Rnor5.0
RGSC_v3.4	16	47,472,870 - 47,473,032	UniSTS	RGSC3.4
Celera	16	42,286,617 - 42,286,779	UniSTS
RH 3.4 Map	16	439.11	UniSTS
Cytogenetic Map	16	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	85	59	6	349	185	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017966 ⟹ ENSRNOP00000017966

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	50,991,096 - 51,154,526 (+)	Ensembl
mRatBN7.2 Ensembl	16	44,258,372 - 44,421,812 (+)	Ensembl
Rnor_6.0 Ensembl	16	47,368,768 - 47,533,816 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000162186 ⟹ ENSRNOP00000109755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	51,093,029 - 51,154,526 (+)	Ensembl

RefSeq Acc Id:

NM_001109111 ⟹ NP_001102581

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	50,991,096 - 51,154,526 (+)	NCBI
mRatBN7.2	16	44,258,372 - 44,421,812 (+)	NCBI
Rnor_6.0	16	47,368,768 - 47,533,816 (+)	NCBI
Rnor_5.0	16	47,091,900 - 47,254,470 (+)	NCBI
RGSC_v3.4	16	47,456,709 - 47,624,245 (+)	RGD
Celera	16	42,271,804 - 42,433,958 (+)	RGD

Sequence:

show sequence

CACCCTTTCCTCTCGAAAGTCTTGTGGTTTCCCTAGAAGACGGAAAGAGGTTGGGAAGGTTGCA
GACTTTTTTCTTTAGACTTCTTTCTCGTCCAGAAAACTCCTAAATCCCCAAAGGGTCTGGCGGA
GAGGAGACACCTCGGGTTGGAGAGGAGGGAGCGAGCCGAGCATTCCTTCGCCCTCCCGCCTCCC
ACCTGGCCTCGCCGCTCCCCTCCCCCGCGCGGGTTCAGCCCCGCGTCCCGCCGCGGCCGCCCCG
GCAGCTGCAGGGTTAAGCTCAGGAATGTGGCGGCGAGGAATGTGCATGCAGATGAGGCGGGCGC
GGGGCGGGCCGGGGGCGGGCCGCATGCTAATCGCACGCAAATGAGGAGGCCAGTCGCCGCCGGG
CCGTTGCTCCGCGGAGCTTCCCGGATCCGAGCCCAGACGGCGTCGGCCGGGGCAGCCTGGGCGC
CGCGACCCTCGGCAGCCACAGGGGGACGGGGAGGAGGAGGAAGAGGCGGAGGCAGCGGCGGCAA
GGAGGAGGAGGGCTCGCTCGCCTGTTCCGACGCAGACATGGTGGACTGATCCCCGGCAGGGCTG
AGAGCAGGGATTCCTGAGGCTCCTCCGCGCGTGGCCCACTGTGCCCCGAGCCCCGCACGCCCCT
TGCCGGCACTCGCGTTCCCGCCGCGCCCCGCGCCGGGTCCCTATGGAGGCGCCGCTCGCCGGCG
AGGCCGCCGACCATGCCTAGGAGAGCCGGGAGCGGGCAGCTGCCGCTACCCCGGGGCTGGGAGG
AGGCCAGGGACTACGACGGCAAGGTTTTCTACATCGACCACAACACCAGGAGGACCAGCTGGAT
CGACCCTCGGGACAGGTTAACGAAGCCGCTGTCCTTCGCTGATTGTGTCGGGGATGAGCTGCCG
TGGGGATGGGAAGCAGGGTTTGACCCTCAGATTGGTGCCTACTACATCGATCACATCAACAAAA
CCACACAGATTGAAGATCCGAGAAAGCAGTGGAGGGGCGAGCAGGAGAAGATGCTCAAAGACTA
TCTCTCTGTGGCTCAGGATGCACTCAGGACGCAAAAGGAACTGTACCACGTGAAGGAGCAGAGG
CTGGCGCTAGCCCTTGATGAATATGTGCGGTTAAATGATGCCTACAAAGAAAAGTCAAGCTCTC
ACACAAGCCTCTTCTCAGGATCTTCATCTAGCACTAAATATGATCCTGATATTTTAAAAGCTGA
GATCTCCACCACACGATTAAGGGTTAAAAAGCTGAAAAGAGAACTCTCCCAAATGAAGCAGGAA
CTTCTCTATAAGCAACAAGGCTTTGAAACGCTGCAACAAATTGATGAAAAGATGTCTGGAGGTC
AGAGTGGATATGAACTTAGTGAAGCCAAAGCCATCCTGACGGAACTGAAATCTATCAGAAAAGC
AATCAGCTCAGGAGAAAAGGAAAAGCAAGATCTGATGCAGAGTCTGGCTAAACTGCAGGAGCGA
TTTCATTTGGATCAGAACATGGGCAGTTCCGAGCCGGATCTGAGATGTAGTCCTGTGAATTCTC
ACCTCTCTCTGTCCAGACAGACCCTTGATGCTGGGTCACAGACAAGCATTTCTGGAGATATTGG
GGTGCGAAGCAGATCAAATTTAGCTGAGAAGGTCAGACTGAGTCTCCAGTATGAAGAAGCCAAA
AGAAGCATGGCTAACTTGAAAATTGAACTGTCAAAGTTGGATGGTGAGGCCTGGCCTGGGGCTC
TGGATGTGGAGAAGGAGAAGTTGATGCTGATTAATGAAAAAGAAGAGCTTCTGAAGGAGCTGCA
GTTCATCACACCCCAGAAACGCACACAAGACGAGCTGGAGCGCCTGGAAGCAGAACGCCAGCGC
CTGGAGGAGGAGCTGGTGGCTGCTCGGGGCTTGCCGAGCAGGGCGCTGGCTGAGAGATTGAAAT
TGGAAGAGAAAAGAAAAGAGCTGCTACAGAAACTTGAAGAAACTACTAAATTAACTACTTACCT
GTATTCACAACTTAAAAGCCTCTCGTCCAGCACACTGTCCATGTCATCTGGGAGCAGTCTGGGG
TCGCTGGCCTCCAGCCGGGGCTCTCTGAACACCTCCAGCAGAGGCTCACTCAACTCCCTCAGTT
CCAGTGACCTCTATTACAGCAGCCAGGGCGACCAGATGGACACAGATTATCAGTACAAACTGGA
CTTCCTTCTTCAAGAGAAGGGTGGCTACATTCCTTCCGGACCTATCACCACCATCCACGAAAAT
GAGGTGGTCAAGTCCCCCAGCCAGCCCGGCCAGAGTGGGCTCTGTGGGTTGGGAGTTGCAGCCA
CCAGCCATACTCCCCCACTGACGGAGGCCTCTAAGTCGGTGACGTCCCTTTCCTCCAGGTCCTC
TCTCTCCTCCTTGTCTCCTCCTGGCTCTCCTCTGGTCTTGGACAGCACATTTCCAGGGTCTTCT
CATGACACCTCTCCGCACCAGTTCACTGCTGACTTGGAAGACTGTGAGTTGAGTCGCCACTTTG
CTGACATTGGCCTCGGTGAGAATCAGGTCTTGCTGGACTCAGACTCGGGAGGACCATCTCAGTC
TCTCCTTGAGGATAAAGACCTTGATGAATGCACTGGAGGGCTGCTGTATGAAGGATCAGCAGAT
GTGGAAAAGTCGTTACCCAAAAGAAGAGGACTTCATCTTCGAGGAGACAAGACTGCTCGTGTGT
CCGCAGCGGCCTCTGATGAGTCTGTGGCTGGAGACAGTGGGGTCTACGAAGCTTCTGTGAAGCA
GCCTGGCGAGATTGAAGACATTCCCTACAGGGAAGAGGATGTCACCATTGTGGAGACTGCACAG
GTGCAGATAGGACTCAGATACGATACAAAGAGTTCAAGTTTCATGGTGATTATAGCACAACTCC
GAAACCTGCATGCCTTCTCGATACCTCATTCTTCAAAGGTGTATTTTAGGGTCGCCGTGCTTCC
CTCCTCGGCAGATGTCAGCTGTCTGTTCCGCACAAAAGTTCATCCGCCCACGGAATCTGTGCTG
TACAACGATGTGTTCAGGGTGGCCATTTCTCAGGTGGTCCTTCAGCAGAAGACGCTGAGAGTCG
ATCTCTGCTCTGTCAGTAAACGCCGCAGGGAGGAATGCCTGGCTGGGACGCAGATCAGCTTGGC
GGATTTACCATTTTCCAATGAGATTTTCATGCTGTGGTATAATTTGCTTCCTTCCAAGCAAATA
CCTTGCAAGAAGAAGGAAGAAGGAGGCGGGCAGCCTGGTGCTCAGTCACCGCAGCCCGCACTTG
ACTCTGCAGACTTGGACGCTGTGTCAGCCTTACTCGCGAGAACTTCAGCTGAGCTGTTGGCTGT
GGAGCAAGAACTGGCCCAAGAGGAGGAGGAGGAGGAAGAGGAGGAACTGAGGCCAGAGCATCGG
GGTCCAGGGGAAGATTGTTTAACGATGCTAAGAGAGGCCTCTGCCGAAACTGTGGCTGCGAAAG
AGTCTGGGGTTCACTTGGCAGAGGGCGGTCACTGCCCAGAAGACCCGAGTCCATGCACTAGGGG
GCCTGGGACAAGCAGAGACCAGTGTCGGAAGGAGAAGGGGCGCACTGAAGACCCCGGCCAGCCA
GCAACTGCGGTTCCCACCCTGGTGGATAAGGAGACGAATACAGATGAAGCAGTTGACAGCAACA
TTGCAGTTCGCCCAAAAGACCGCAGCAGCCTGAGCTCTCAGCACCATCCGTTTGTGAGAAGCAG
CGTGATCGTGCGTTCACAAACCTTTTCCCCAGGCGAGAGGAGCCAGTACATCTGCAGGTTAAAT
CGCAGTGACAGTGACAGCTCAACCTTGGCCAAAAAGTCCTTGTTTGTGAGAAACTCCACTGAGC
GACGCAGTTTGCGTGTCAAAAGGGCAGTCTGCCAGCCCACCCTCAGGAGGACTGCTCAGGAGTG
CCCTGTGCGCACATCTCTTGACCTGGAGCTGGACCTGCAGGCCTCCCTGACCCGCCAGAGTCGC
CTCAACGACGAGCTGCAGGCCCTGCGAGGCCTACAGCAGAAGCTGGAGGAGCTGAAAGCCCAGG
GAGAGACCGACCTGCCCCCAGGCATGCTGGGGGACGAGAGATTCCAGAAGCTTCTGAAGCAAGC
AGAGAAGCAGGCTGAGCAGACAAAAGAGGAGCAGAAGCAAGACTTGAACGCAGAGAGGTTGATG
AGACAGGTCTCCAAGGATGTGTGCCGGCTGCGGGAGCAGAGCCAGAAGGAGCCTCGACAGGTGC
AGTCCTTCAGGGAGAAGATTGCCTACTTCACACGAGCAAAGATCAGCATCCCGTCCCTGCCGGC
TGATGACGTGTGACCCTGTGACTGAACACCGCTTCTCAGCTGCTTACTTTCCAAGGGACGGTCA
AAGACTGACTATTCCCGTTTTTGTTGTTTTTTATTTTTTTTGTTGGGGTTAGGGCTTGTGTTTC
CTGTAACATAACTGTCAACCCTTGAAGAGCTTCCATTTCACATCCGTTTCATCAGGTTAATTTG
TAAATTACTTTGAATGTAACTCTTACGTGCTTTGAGAAGAAAAAAAATCACCTAACAAAAATGG
GGTCATCTGGTCCACAAATGTCGTACAGTATGTGTTAGCACTGGGCTTCACTGTAGATGGAACA
CAGGTAGCAGGTGTCCAGTGTCTGCCCGCTGAGCCGACTGGGCCGGCAGCTGTCCAGCAGCCCC
TGAAGCTTTCGCCACAGTGTGCCCTGAACTAGAGAGCCACTCACTCCATCGACTCACTCCATCG
AAGTGCACTCAAGCGAGCTTCTGCGTCTGAGGCTGAGGGCGGGCATATGAGAATCGGGGGTGAG
CTCCTGCTGTAGAGAGCTGCAGTCGGGGGGCAGGGGAGGGCATCTTTCAAAAACACTGAGGAAA
CTCAGCCAATCCATCACAGGCTGAATCTGCCTGGCTTCATGTCAGTGTCTGGCCTGCCAGGGAG
ATCGTGGTGGCCCTGGCCTCTGACAGTGCAGGCAGTGCAGAGGGGACAGCATTGAGGAGAGCTG
AGGACAGGGCGCATCGTGATGAGATCAAACTTGCCAGAGTTTGTCATCGGGTTCGTACACTCCC
TAGAAATTATTTTGTAGCTGTTGTCCTCAGGGGATTCTGTCAGCAATGCAGAAACAGAGTGTGG
CTGAGGGCACTTGTAGTCAGTGTGGACTGGATCATTTAAAATATATATATATTCTGGATGGACA
CGCAAGCTTGACATAGGAATTGGTCAAAGTGCCGTGTTCTCCAGGCTGGGTTTAACTTCCCAGA
CCCCGGGCACTTGTTTAAAAAAACAAAAACAACAAAACTCAGTATAGTTTAGCCAGCATAAACA
TGTTAAAATAAATACTTTTTTAGGTAATTTAATTACTCATTCCATCATACTGGAAGAAGCCGTG
TTTTGGTGAGCCATCTTATATAGCAAGCTAAATTATTTTTATTTTTTTAGTGCAAAATAATTTT
TATAGGAATTAATAGAAGAAAGGCAAGAAAAAATTTTGTTTAAAAAAAGCTATGTTCTGCTGGA
ATCCCCACTGGTAAGGATTTTTATCTTCTTGAATCGATGTATATTTTAGAAAGTTCATTTTTAT
CAGAATCAAAGTTCGTTCCTACTCAGCTAGGATTTCAGCTATCAAGTTACTGCACCTAACACAC
AGTCATTTCCCTCTAAATGTTCCACAGCTTAGAGGATGTAACTGGACAGGACCCCACTTGGAAC
AAAAAGAAGCCTGGTGGGGCCCTGAGGGCAGACTCCTGTGCTGACCACTTTGCCCTGTAGGCGA
ACGGAGGAAGGGGCGTGCCGTCCTTCCTGGTCAAGCTTAAATTGAGCACAGAAGTTGACTTAAT
ACAGCTCTAGATGAAGGTCACCTGTCTTCAGCGTCATAGTTTGACCCATGAAAATGTTCATAGA
ACTTTGTGTAGTTGTACCGTATGATTTTATTTTTCTTCAATTATTTATTTACGGTCTTATTTAT
GTTCTCTTTAATATATAGTTTGGTTCTGGCCATCTTAAATGTCGGACTTACAAGAGGCTATATT
GGAGTATTTACAACTCTATGATCTTCATCAAATTTATCACTAACTTTTTGTAATACAAAAAGTT
TCAGATGAGTATTAAAGAATAAACTGTGTCTCAGGCTGGTAGTTCAGAGTTGTGACTGAGGGAC
TTTGGTTTTATTTTATAAAACATGCTCATTTCTAACATGAGAGAAGCTATTCATTCTGATAGAA
TCCTTTCCCACACTCTAAAAGTCGGCAGTAGTGTTGTGTACTTACAGGCAGCTTTTTGTAGGTC
TGTCACATTTGTATTGACCCAAATGATTAAAGGAAAAAACATTTTACTAACTTGATCACAAAAC
CATATGGAAAATAAAAATTTTAATATTATTAAAAATATTTTTAAACTTAGAATTTATTCTGCAC
AGGGTAAAAAAAGAGTTTAATATTTAGCTCTCAATTTTGGATTATCAGTATATTACAGTTTTGT
ATATCAGACTCAAGTGTTACAGGTACAGAAAGAATATTAACTTGCCAAATGAACGAAGTTTAGC
TGAGTCTCTGTAGTATACAAAGTAAATACATTTAAACTTTCTTTGCTGTGTATTTATGTTGTAT
TAAATATGAGAAGCTCAGGACTGAACTAAATATTTAATCAGGTTAAATTCTGAATATGTTTCTG
CTTTCCTTTGTCCTGTTTGTAAAAGTGTGCAAATATATCACCCGGATTAACTCCCACTGCTGCC
CTTGCCCTGTGTCTGTGGATGGAAAACACTCAGTGATTTCTTTTTTCTAAAACAGAATACGTGT
TTCCTGACACTGCATTTTAGTGTTGCTTATTGTTCAGCTAATTTCCCTGATTGGCACAAATACA
AGAATCTACTTGAACC

hide sequence

RefSeq Acc Id:

XM_039094772 ⟹ XP_038950700

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	51,083,792 - 51,154,529 (+)	NCBI
mRatBN7.2	16	44,351,091 - 44,421,815 (+)	NCBI

RefSeq Acc Id:

XM_063275643 ⟹ XP_063131713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	51,062,789 - 51,154,529 (+)	NCBI

RefSeq Acc Id:

XM_063275644 ⟹ XP_063131714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	51,083,791 - 51,154,529 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102581	(Get FASTA)	NCBI Sequence Viewer
	XP_038950700	(Get FASTA)	NCBI Sequence Viewer
	XP_063131713	(Get FASTA)	NCBI Sequence Viewer
	XP_063131714	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL78921	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017966
	ENSRNOP00000017966.4
	ENSRNOP00000109755
	ENSRNOP00000109755.1

RefSeq Acc Id:

NP_001102581 ⟸ NM_001109111

- UniProtKB:

D4AEJ5 (UniProtKB/TrEMBL), A6JPK1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWE
AGFDPQIGAYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALA
LDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYK
QQGFETLQQIDEKMSGGQSGYELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLD
QNMGSSEPDLRCSPVNSHLSLSRQTLDAGSQTSISGDIGVRSRSNLAEKVRLSLQYEEAKRSMA
NLKIELSKLDGEAWPGALDVEKEKLMLINEKEELLKELQFITPQKRTQDELERLEAERQRLEEE
LVAARGLPSRALAERLKLEEKRKELLQKLEETTKLTTYLYSQLKSLSSSTLSMSSGSSLGSLAS
SRGSLNTSSRGSLNSLSSSDLYYSSQGDQMDTDYQYKLDFLLQEKGGYIPSGPITTIHENEVVK
SPSQPGQSGLCGLGVAATSHTPPLTEASKSVTSLSSRSSLSSLSPPGSPLVLDSTFPGSSHDTS
PHQFTADLEDCELSRHFADIGLGENQVLLDSDSGGPSQSLLEDKDLDECTGGLLYEGSADVEKS
LPKRRGLHLRGDKTARVSAAASDESVAGDSGVYEASVKQPGEIEDIPYREEDVTIVETAQVQIG
LRYDTKSSSFMVIIAQLRNLHAFSIPHSSKVYFRVAVLPSSADVSCLFRTKVHPPTESVLYNDV
FRVAISQVVLQQKTLRVDLCSVSKRRREECLAGTQISLADLPFSNEIFMLWYNLLPSKQIPCKK
KEEGGGQPGAQSPQPALDSADLDAVSALLARTSAELLAVEQELAQEEEEEEEEELRPEHRGPGE
DCLTMLREASAETVAAKESGVHLAEGGHCPEDPSPCTRGPGTSRDQCRKEKGRTEDPGQPATAV
PTLVDKETNTDEAVDSNIAVRPKDRSSLSSQHHPFVRSSVIVRSQTFSPGERSQYICRLNRSDS
DSSTLAKKSLFVRNSTERRSLRVKRAVCQPTLRRTAQECPVRTSLDLELDLQASLTRQSRLNDE
LQALRGLQQKLEELKAQGETDLPPGMLGDERFQKLLKQAEKQAEQTKEEQKQDLNAERLMRQVS
KDVCRLREQSQKEPRQVQSFREKIAYFTRAKISIPSLPADDV

hide sequence

Ensembl Acc Id:

ENSRNOP00000017966 ⟸ ENSRNOT00000017966

RefSeq Acc Id:	XP_038950700 ⟸ XM_039094772
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063131713 ⟸ XM_063275643
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063131714 ⟸ XM_063275644
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000109755 ⟸ ENSRNOT00000162186

Protein Domains

C2 WW

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AEJ5-F1-model_v2	AlphaFold	D4AEJ5	1-1194	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700086

Promoter ID:

EPDNEW_R10610

Type:

initiation region

Name:

Wwc2_1

Description:

WW and C2 domain containing 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	47,369,186 - 47,369,246	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559427	AgrOrtholog
BioCyc Gene	G2FUF-11419	BioCyc
Ensembl Genes	ENSRNOG00000013248	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017966	ENTREZGENE
	ENSRNOT00000017966.7	UniProtKB/TrEMBL
	ENSRNOT00000162186	ENTREZGENE
	ENSRNOT00000162186.1	UniProtKB/TrEMBL
Gene3D-CATH	2.20.70.10	UniProtKB/TrEMBL
	2.60.40.150	UniProtKB/TrEMBL
InterPro	C2_dom	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	C2_WWC	UniProtKB/TrEMBL
	WW_dom_sf	UniProtKB/TrEMBL
	WW_Rsp5_WWP	UniProtKB/TrEMBL
	WWC/KIBRA_Hippo_Reg	UniProtKB/TrEMBL
KEGG Report	rno:498630	UniProtKB/TrEMBL
NCBI Gene	498630	ENTREZGENE
PANTHER	BOMB/KIRA PROTEINS	UniProtKB/TrEMBL
	PROTEIN WWC2	UniProtKB/TrEMBL
Pfam	PF00397	UniProtKB/TrEMBL
	WWC1	UniProtKB/TrEMBL
PhenoGen	Wwc2	PhenoGen
PROSITE	PS50004	UniProtKB/TrEMBL
	WW_DOMAIN_1	UniProtKB/TrEMBL
	WW_DOMAIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013248	RatGTEx
SMART	SM00456	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/TrEMBL
	WW_Rsp5_WWP	UniProtKB/TrEMBL
UniProt	A0ABK0M3V0_RAT	UniProtKB/TrEMBL
	A6JPK1	ENTREZGENE, UniProtKB/TrEMBL
	D4AEJ5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-23	Wwc2	WW and C2 domain containing 2	Wwc2	WW, C2 and coiled-coil domain containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Wwc2	WW, C2 and coiled-coil domain containing 2	RGD1559427_predicted	similar to BH3-only member B protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1559427_predicted	similar to BH3-only member B protein (predicted)	LOC498630	similar to BH3-only member B protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498630	similar to BH3-only member B protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar