Tead1 (TEA domain transcription factor 1) - Rat Genome Database

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Gene: Tead1 (TEA domain transcription factor 1) Rattus norvegicus
Analyze
Symbol: Tead1
Name: TEA domain transcription factor 1
RGD ID: 1549742
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including hippo signaling; positive regulation of cell growth; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including cellular response to retinoic acid; embryonic organ development; and transition between fast and slow fiber. Predicted to be located in nucleoplasm. Predicted to be part of TEAD-YAP complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: TEA domain family member 1; TEF-1; transcriptional enhancer factor TEF-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81176,227,175 - 176,445,122 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)EnsemblGRCr8
mRatBN7.21166,791,900 - 167,010,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1175,125,056 - 175,337,910 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,311,084 - 182,523,980 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01175,006,836 - 175,218,950 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01177,495,500 - 177,714,795 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1177,495,782 - 177,707,061 (+)Ensemblrn6Rnor6.0
Rnor_5.01184,473,090 - 184,690,968 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41170,481,601 - 170,696,621 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1164,664,658 - 164,874,391 (+)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-bromohexadecanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
alcohol  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
capecitabine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
doxifluridine  (ISO)
ethanol  (ISO)
Evodiamine  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
geldanamycin  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sunitinib  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
verteporfin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
TEAD-YAP complex  (IEA,ISO)
transcription regulator complex  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Kusumanchi P, etal., Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7958896   PMID:11118619   PMID:11306707   PMID:12477932   PMID:12861002   PMID:14762206   PMID:16207754   PMID:17689488   PMID:18332127   PMID:18579750   PMID:18978355   PMID:19004856  
PMID:19324877   PMID:20123905   PMID:20516196   PMID:21385842   PMID:22082260   PMID:24344135   PMID:25796446   PMID:26045994   PMID:26902285   PMID:27288457   PMID:27359056   PMID:33963717  


Genomics

Comparative Map Data
Tead1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81176,227,175 - 176,445,122 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)EnsemblGRCr8
mRatBN7.21166,791,900 - 167,010,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1175,125,056 - 175,337,910 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01182,311,084 - 182,523,980 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01175,006,836 - 175,218,950 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01177,495,500 - 177,714,795 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1177,495,782 - 177,707,061 (+)Ensemblrn6Rnor6.0
Rnor_5.01184,473,090 - 184,690,968 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41170,481,601 - 170,696,621 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1164,664,658 - 164,874,391 (+)NCBICelera
Cytogenetic Map1q33NCBI
TEAD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381112,674,421 - 12,944,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1112,674,421 - 12,944,737 (+)Ensemblhg38GRCh38
GRCh371112,695,968 - 12,966,284 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,652,545 - 12,922,875 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341112,742,300 - 12,922,859NCBI
Celera1112,823,287 - 13,092,362 (+)NCBICelera
Cytogenetic Map11p15.3NCBI
HuRef1112,376,359 - 12,646,393 (+)NCBIHuRef
CHM1_11112,694,856 - 12,965,213 (+)NCBICHM1_1
T2T-CHM13v2.01112,766,927 - 13,037,265 (+)NCBIT2T-CHM13v2.0
Tead1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397112,278,563 - 112,505,991 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7112,278,525 - 112,506,014 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm387112,679,356 - 112,906,784 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7112,679,318 - 112,906,807 (+)Ensemblmm10GRCm38
MGSCv377119,822,834 - 120,050,319 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv367112,470,774 - 112,691,171 (+)NCBIMGSCv36mm8
Celera7112,654,274 - 112,881,298 (+)NCBICelera
Cytogenetic Map7F1NCBI
cM Map758.8NCBI
Tead1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541428,175,543 - 28,333,856 (+)Ensembl
ChiLan1.0NW_00495541428,166,562 - 28,341,275 (+)NCBIChiLan1.0ChiLan1.0
TEAD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2915,119,897 - 15,389,782 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11115,082,890 - 15,352,965 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01112,841,564 - 13,111,506 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11112,535,447 - 12,804,052 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1112,624,281 - 12,796,541 (+)EnsemblpanPan2panpan1.1
TEAD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12135,667,862 - 35,935,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2135,566,865 - 35,934,438 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2135,171,510 - 35,440,389 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02136,550,376 - 36,819,260 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2136,637,742 - 36,816,915 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12135,809,718 - 36,078,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02135,986,072 - 36,255,153 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02136,273,664 - 36,543,422 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tead1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494749,574,726 - 49,824,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365285,607,987 - 5,856,678 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365285,607,993 - 5,774,161 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEAD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl246,400,066 - 46,670,472 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1246,396,490 - 46,670,619 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2249,852,052 - 50,007,352 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TEAD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,897,725 - 52,167,655 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,905,198 - 52,076,909 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038149,493,887 - 149,764,044 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tead1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247664,694,016 - 4,928,302 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247664,694,337 - 4,935,121 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tead1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1288,615,987 - 88,824,824 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tead1
1453 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:60
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000021020
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)1137611478182611478Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1142582336182383862Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1168063662213063662Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1140833106185833106Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1131243790176243790Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1153680016182383862Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1153680016183564652Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1172718770228180370Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1175967553200707874Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1174182140176235262Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1170078537182384005Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436178317588Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
8693608Alc24Alcohol consumption QTL 242.30.74drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1159863716177663210Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1165707719210707719Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1173363824227535316Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436180021436Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1140915717185915717Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat

Markers in Region
D1Rat55  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81176,235,132 - 176,235,262 (+)Marker Load Pipeline
Rnor_5.01184,481,328 - 184,481,458NCBIRnor5.0
Rnor_5.01184,481,327 - 184,481,458NCBIRnor5.0
RGSC_v3.41170,489,843 - 170,489,972UniSTSRGSC3.4
RGSC_v3.41170,489,842 - 170,489,972RGDRGSC3.4
Celera1164,672,382 - 164,672,511UniSTS
RGSC_v3.11170,609,777 - 170,609,906RGD
RH 3.4 Map11322.3RGD
RH 3.4 Map11322.3UniSTS
RH 2.0 Map1854.0RGD
SHRSP x BN Map183.52RGD
FHH x ACI Map180.0199RGD
Cytogenetic Map1q34UniSTS
D1Rat280  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81176,231,210 - 176,231,333 (+)Marker Load Pipeline
mRatBN7.21166,796,656 - 166,796,779 (+)MAPPERmRatBN7.2
Rnor_6.01177,499,817 - 177,499,939NCBIRnor6.0
Rnor_5.01184,477,407 - 184,477,529UniSTSRnor5.0
RGSC_v3.41170,485,920 - 170,486,043UniSTSRGSC3.4
RGSC_v3.41170,485,919 - 170,486,043RGDRGSC3.4
Celera1164,668,508 - 164,668,585UniSTS
RGSC_v3.11170,605,679 - 170,605,995RGD
SHRSP x BN Map183.5599UniSTS
SHRSP x BN Map183.5599RGD
Cytogenetic Map1q34UniSTS
D1Got160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,844,742 - 166,844,946 (+)MAPPERmRatBN7.2
Rnor_6.01177,547,893 - 177,548,096NCBIRnor6.0
Rnor_5.01184,525,433 - 184,525,636UniSTSRnor5.0
RGSC_v3.41170,536,329 - 170,536,533RGDRGSC3.4
RGSC_v3.41170,536,330 - 170,536,533UniSTSRGSC3.4
Celera1164,716,634 - 164,716,837UniSTS
RGSC_v3.11170,656,264 - 170,656,467RGD
RH 3.4 Map11320.1UniSTS
RH 3.4 Map11320.1RGD
RH 2.0 Map1853.7RGD
Cytogenetic Map1q34UniSTS
AU046756  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,946,237 - 166,946,439 (+)MAPPERmRatBN7.2
Rnor_6.01177,650,233 - 177,650,434NCBIRnor6.0
Rnor_5.01184,626,409 - 184,626,610UniSTSRnor5.0
RGSC_v3.41170,638,660 - 170,638,861UniSTSRGSC3.4
Celera1164,818,149 - 164,818,350UniSTS
Cytogenetic Map1q34UniSTS
BE107218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,869,149 - 166,869,329 (+)MAPPERmRatBN7.2
Rnor_6.01177,572,943 - 177,573,122NCBIRnor6.0
Rnor_5.01184,549,653 - 184,549,832UniSTSRnor5.0
RGSC_v3.41170,560,665 - 170,560,844UniSTSRGSC3.4
Celera1164,741,081 - 164,741,260UniSTS
RH 3.4 Map11322.3UniSTS
Cytogenetic Map1q34UniSTS
UniSTS:224609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,002,735 - 167,002,927 (+)MAPPERmRatBN7.2
Rnor_6.01177,706,941 - 177,707,132NCBIRnor6.0
Rnor_5.01184,683,117 - 184,683,308UniSTSRnor5.0
RGSC_v3.41170,695,896 - 170,696,087UniSTSRGSC3.4
Celera1164,874,469 - 164,874,660UniSTS
Cytogenetic Map1q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 82 59 6 346 182 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001198589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001435800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY529194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY529195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY529196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY529197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY529198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021020   ⟹   ENSRNOP00000021020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Rnor_6.0 Ensembl1177,495,782 - 177,706,863 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090042   ⟹   ENSRNOP00000072311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Rnor_6.0 Ensembl1177,569,618 - 177,707,061 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096192   ⟹   ENSRNOP00000078399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,300,421 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096896   ⟹   ENSRNOP00000082861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,874,921 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099524   ⟹   ENSRNOP00000077383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100503   ⟹   ENSRNOP00000079346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101620   ⟹   ENSRNOP00000085279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,924,981 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104208   ⟹   ENSRNOP00000077946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,300,421 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105758   ⟹   ENSRNOP00000092848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,227,175 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111991   ⟹   ENSRNOP00000079105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1176,300,421 - 176,438,198 (+)Ensembl
mRatBN7.2 Ensembl1166,792,628 - 167,003,369 (+)Ensembl
RefSeq Acc Id: NM_001198589   ⟹   NP_001185518
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,227,175 - 176,437,197 (+)NCBI
mRatBN7.21166,792,620 - 167,002,658 (+)NCBI
Rnor_6.01177,495,782 - 177,706,863 (+)NCBI
Rnor_5.01184,473,090 - 184,690,968 (+)NCBI
Celera1164,664,658 - 164,874,391 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082763   ⟹   XP_038938691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,386,640 - 176,445,122 (+)NCBI
mRatBN7.21166,791,901 - 167,010,591 (+)NCBI
RefSeq Acc Id: XM_039082788   ⟹   XP_038938716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,300,367 - 176,445,122 (+)NCBI
mRatBN7.21166,865,822 - 167,010,591 (+)NCBI
RefSeq Acc Id: XM_063267456   ⟹   XP_063123526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,291,847 - 176,445,122 (+)NCBI
RefSeq Acc Id: XM_063267458   ⟹   XP_063123528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,283,587 - 176,445,122 (+)NCBI
RefSeq Acc Id: XM_063267467   ⟹   XP_063123537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,300,367 - 176,445,122 (+)NCBI
RefSeq Acc Id: XM_063267471   ⟹   XP_063123541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,291,843 - 176,435,076 (+)NCBI
RefSeq Acc Id: XM_063267472   ⟹   XP_063123542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,227,261 - 176,445,122 (+)NCBI
RefSeq Acc Id: XM_063267476   ⟹   XP_063123546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,283,386 - 176,445,122 (+)NCBI
RefSeq Acc Id: XM_063267482   ⟹   XP_063123552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81176,227,261 - 176,445,122 (+)NCBI
RefSeq Acc Id: NP_001185518   ⟸   NM_001198589
- UniProtKB: A6I870 (UniProtKB/TrEMBL),   A0A8I5ZKU4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072311   ⟸   ENSRNOT00000090042
Ensembl Acc Id: ENSRNOP00000021020   ⟸   ENSRNOT00000021020
RefSeq Acc Id: XP_038938691   ⟸   XM_039082763
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZM31 (UniProtKB/TrEMBL),   A0A8I6A1B4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938716   ⟸   XM_039082788
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZM31 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092848   ⟸   ENSRNOT00000105758
Ensembl Acc Id: ENSRNOP00000085279   ⟸   ENSRNOT00000101620
Ensembl Acc Id: ENSRNOP00000082861   ⟸   ENSRNOT00000096896
Ensembl Acc Id: ENSRNOP00000077946   ⟸   ENSRNOT00000104208
Ensembl Acc Id: ENSRNOP00000078399   ⟸   ENSRNOT00000096192
Ensembl Acc Id: ENSRNOP00000077383   ⟸   ENSRNOT00000099524
Ensembl Acc Id: ENSRNOP00000079105   ⟸   ENSRNOT00000111991
Ensembl Acc Id: ENSRNOP00000079346   ⟸   ENSRNOT00000100503
RefSeq Acc Id: XP_063123542   ⟸   XM_063267472
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2N3 (UniProtKB/TrEMBL),   A0A8I5ZKU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123552   ⟸   XM_063267482
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063123546   ⟸   XM_063267476
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2N3 (UniProtKB/TrEMBL),   A0A8I5ZKU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123528   ⟸   XM_063267458
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZMT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123541   ⟸   XM_063267471
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZMT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123526   ⟸   XM_063267456
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2N3 (UniProtKB/TrEMBL),   A0A8I5ZKU4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123537   ⟸   XM_063267467
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y8C5 (UniProtKB/TrEMBL),   A0A8I5ZKU4 (UniProtKB/TrEMBL)
Protein Domains
TEA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2N3-F1-model_v2 AlphaFold A0A0G2K2N3 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1549742 AgrOrtholog
BioCyc Gene G2FUF-57782 BioCyc
Ensembl Genes ENSRNOG00000015488 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021020 ENTREZGENE
  ENSRNOT00000021020.6 UniProtKB/TrEMBL
  ENSRNOT00000090042.3 UniProtKB/TrEMBL
  ENSRNOT00000096192.2 UniProtKB/TrEMBL
  ENSRNOT00000099524.2 UniProtKB/TrEMBL
  ENSRNOT00000104208 ENTREZGENE
  ENSRNOT00000104208.2 UniProtKB/TrEMBL
  ENSRNOT00000105758 ENTREZGENE
  ENSRNOT00000105758.2 UniProtKB/TrEMBL
  ENSRNOT00000111991.2 UniProtKB/TrEMBL
Gene3D-CATH 2.70.50.80 UniProtKB/TrEMBL
  6.10.20.40 UniProtKB/TrEMBL
InterPro TEA/ATTS UniProtKB/TrEMBL
  TEA/ATTS_sf UniProtKB/TrEMBL
  TEC1_TEAD_TF UniProtKB/TrEMBL
  TEF UniProtKB/TrEMBL
  YBD UniProtKB/TrEMBL
KEGG Report rno:361630 UniProtKB/TrEMBL
NCBI Gene 361630 ENTREZGENE
PANTHER TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED UniProtKB/TrEMBL
  TRANSCRIPTIONAL ENHANCER FACTOR TEF-1 UniProtKB/TrEMBL
Pfam TEA UniProtKB/TrEMBL
  YBD UniProtKB/TrEMBL
PhenoGen Tead1 PhenoGen
PIRSF TEF UniProtKB/TrEMBL
PRINTS TEADOMAIN UniProtKB/TrEMBL
PROSITE TEA_1 UniProtKB/TrEMBL
  TEA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015488 RatGTEx
SMART TEA UniProtKB/TrEMBL
UniProt A0A0G2K2N3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y7H2_RAT UniProtKB/TrEMBL
  A0A8I5Y8C5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKU4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZM31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZMT2 ENTREZGENE
  A0A8I6A1B4 ENTREZGENE
  A6I870 ENTREZGENE, UniProtKB/TrEMBL
  F1M7P3_RAT UniProtKB/TrEMBL
  Q6QQT9_RAT UniProtKB/TrEMBL
  Q6QQU0_RAT UniProtKB/TrEMBL
  Q6QQU1 ENTREZGENE, UniProtKB/TrEMBL
  Q6QQU3_RAT UniProtKB/TrEMBL
UniProt Secondary Q6QQU2 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Tead1  TEA domain transcription factor 1  Tead1  TEA domain family member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-15 Tead1  TEA domain family member 1      Symbol and Name status set to provisional 70820 PROVISIONAL