Nono (non-POU domain containing, octamer-binding) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Nono (non-POU domain containing, octamer-binding) Rattus norvegicus
Analyze
Symbol: Nono
Name: non-POU domain containing, octamer-binding
RGD ID: 1549738
Description: Enables lncRNA binding activity. Involved in several processes, including cellular response to angiotensin; cellular response to hypoxia; and circadian rhythm. Predicted to be located in nuclear matrix. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in paraspeckles. Human ortholog(s) of this gene implicated in cardiomyopathy; intellectual disability; and syndromic X-linked intellectual disability 34. Orthologous to human NONO (non-POU domain containing octamer binding); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC109026; non-POU domain-containing octamer-binding protein; non-POU-domain-containing, octamer-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,594,116 - 70,611,976 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX70,593,888 - 70,611,979 (+)EnsemblGRCr8
mRatBN7.2X66,554,131 - 66,571,992 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,554,098 - 66,571,952 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX68,037,473 - 68,055,333 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,537,880 - 71,555,742 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X69,098,781 - 69,116,641 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,324,365 - 71,342,225 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,324,365 - 71,342,225 (+)Ensemblrn6Rnor6.0
Rnor_5.0X72,175,019 - 72,192,921 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X89,502,318 - 89,520,178 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX66,909,811 - 66,927,662 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
biochanin A  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
chlorpyrifos  (EXP)
chrysene  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
eugenol  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glycogen  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methylparaben  (ISO)
nefazodone  (EXP)
nitrates  (ISO)
ozone  (ISO)
phenobarbital  (ISO)
quercetin  (ISO)
salvianolic acid B  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
tert-butyl hydroperoxide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
fibrillar center  (IEA,ISO)
nuclear matrix  (IEA,ISO)
nuclear speck  (IEA)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)
paraspeckles  (IEA,ISO)
RNA polymerase II transcription regulator complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Brown SA, etal., Science. 2005 Apr 29;308(5722):693-6.
2. A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Das S, etal., Circ Res. 2018 Dec 7;123(12):1298-1312. doi: 10.1161/CIRCRESAHA.118.313207.
3. Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ-NONO heteromer-induced DNA repair. Fu W, etal., Basic Res Cardiol. 2022 Mar 5;117(1):10. doi: 10.1007/s00395-022-00921-y.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. A novel NONO variant that causes developmental delay and cardiac phenotypes. Itai T, etal., Sci Rep. 2023 Jan 18;13(1):975. doi: 10.1038/s41598-023-27770-6.
6. Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases. Kahl A, etal., Sci Rep. 2018 Feb 9;8(1):2701. doi: 10.1038/s41598-018-21063-z.
7. hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures. Marko M, etal., Exp Cell Res. 2010 Feb 1;316(3):390-400. doi: 10.1016/j.yexcr.2009.10.021. Epub 2009 Oct 27.
8. Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects. Mircsof D, etal., Nat Neurosci. 2015 Dec;18(12):1731-6. doi: 10.1038/nn.4169. Epub 2015 Nov 16.
9. Decreased expression of P54(nrb) /NonO correlates with collagen deposition and fibrosis in human aortic dissection. Ren Z, etal., Histopathology. 2014 Oct;65(4):570-80. doi: 10.1111/his.12434. Epub 2014 Aug 1.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Congenital heart defects and left ventricular non-compaction in males with loss-of-function variants in NONO. Scott DA, etal., J Med Genet. 2017 Jan;54(1):47-53. doi: 10.1136/jmedgenet-2016-104039. Epub 2016 Aug 22.
14. Further delineation of the phenotypic spectrum associated with hemizygous loss-of-function variants in NONO. Sewani M, etal., Am J Med Genet A. 2020 Apr;182(4):652-658. doi: 10.1002/ajmg.a.61466. Epub 2019 Dec 28.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16. Novel candidate genes of the PARK7 interactome as mediators of apoptosis and acetylation in multiple sclerosis: An in silico analysis. Vavougios GD, etal., Mult Scler Relat Disord. 2018 Jan;19:8-14. doi: 10.1016/j.msard.2017.10.013. Epub 2017 Oct 24.
17. Knockout of the NONO Gene Inhibits Neointima Formation in a Mouse Model of Vascular Injury. Xu (徐兴丽) X, etal., Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1428-1445. doi: 10.1161/ATVBAHA.119.313581. Epub 2021 Feb 25.
18. Silencing of NONO inhibits abdominal aortic aneurysm in apolipoprotein E-knockout mice via collagen deposition and inflammatory inhibition. Xu X, etal., J Cell Mol Med. 2019 Nov;23(11):7449-7461. doi: 10.1111/jcmm.14613. Epub 2019 Sep 11.
19. Deficiency of NONO is associated with impaired cardiac function and fibrosis in mice. Xu X, etal., J Mol Cell Cardiol. 2019 Dec;137:46-58. doi: 10.1016/j.yjmcc.2019.10.004. Epub 2019 Oct 18.
20. Development of an RNA sequencing-based prognostic gene signature in multiple myeloma. Zamani-Ahmadmahmudi M, etal., Br J Haematol. 2021 Jan;192(2):310-321. doi: 10.1111/bjh.16744. Epub 2020 May 15.
21. Expression of Long Non-coding RNA RGD1566344 in the Brain Cortex of Male Mice After Focal Cerebral Ischemia-Reperfusion and the Neuroprotective Effect of a Non-coding RNA RGD1566344 Inhibitor. Zhang J, etal., Cell Mol Neurobiol. 2021 May;41(4):705-716. doi: 10.1007/s10571-020-00877-4. Epub 2020 May 18.
22. Silencing of Non-POU-domain-containing octamer-binding protein stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice via NF-κB signaling pathway. Zhang K, etal., Int J Cardiol. 2018 Jul 15;263:96-103. doi: 10.1016/j.ijcard.2018.04.018. Epub 2018 Apr 7.
Additional References at PubMed
PMID:15489334   PMID:15790595   PMID:16148043   PMID:16189514   PMID:19217333   PMID:19389484   PMID:19946888   PMID:21507896   PMID:21988832   PMID:22082260   PMID:22416126   PMID:22658674  
PMID:22681889   PMID:22966205   PMID:23555304   PMID:24625528   PMID:25326457   PMID:28712728   PMID:32357304   PMID:37130848  


Genomics

Comparative Map Data
Nono
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,594,116 - 70,611,976 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX70,593,888 - 70,611,979 (+)EnsemblGRCr8
mRatBN7.2X66,554,131 - 66,571,992 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,554,098 - 66,571,952 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX68,037,473 - 68,055,333 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,537,880 - 71,555,742 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X69,098,781 - 69,116,641 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,324,365 - 71,342,225 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,324,365 - 71,342,225 (+)Ensemblrn6Rnor6.0
Rnor_5.0X72,175,019 - 72,192,921 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X89,502,318 - 89,520,178 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX66,909,811 - 66,927,662 (+)NCBICelera
Cytogenetic MapXq22NCBI
NONO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,283,635 - 71,301,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX71,254,270 - 71,301,522 (+)Ensemblhg38GRCh38
GRCh37X70,503,485 - 70,521,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,420,192 - 70,437,743 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X70,286,487 - 70,304,037NCBI
CeleraX70,856,920 - 70,874,896 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX64,319,299 - 64,337,309 (+)NCBIHuRef
CHM1_1X70,396,097 - 70,414,071 (+)NCBICHM1_1
T2T-CHM13v2.0X69,717,744 - 69,735,278 (+)NCBIT2T-CHM13v2.0
Nono
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,473,295 - 100,492,193 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX100,472,924 - 100,492,197 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X101,429,560 - 101,448,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,429,318 - 101,448,591 (+)Ensemblmm10GRCm38
MGSCv37X98,624,990 - 98,643,932 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X97,632,435 - 97,651,308 (+)NCBIMGSCv36mm8
CeleraX88,346,919 - 88,366,346 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX44.14NCBI
Nono
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,833,189 - 10,853,519 (+)Ensembl
ChiLan1.0NW_00495547510,833,514 - 10,853,460 (+)NCBIChiLan1.0ChiLan1.0
NONO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X70,955,998 - 70,973,982 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X70,959,601 - 70,977,585 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X60,547,277 - 60,564,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X70,602,456 - 70,619,937 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,602,456 - 70,619,956 (+)EnsemblpanPan2panpan1.1
NONO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,618,032 - 55,632,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,618,095 - 55,631,388 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX46,445,079 - 46,459,286 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X56,586,957 - 56,601,162 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX56,572,988 - 56,601,161 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X54,554,587 - 54,568,792 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X55,886,312 - 55,900,514 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X55,813,482 - 55,827,924 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nono
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,560,239 - 46,581,000 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936762321,280 - 341,537 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936762322,413 - 343,126 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NONO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X61,082,923 - 61,110,895 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660652,944,350 - 2,963,545 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nono
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249031,562,743 - 1,586,985 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249031,562,818 - 1,583,648 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nono
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X59,099,831 - 59,117,184 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nono
41 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:261
Count of miRNA genes:185
Interacting mature miRNAs:219
Transcripts:ENSRNOT00000004911
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat

Markers in Region
RH139235  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X66,565,448 - 66,565,578 (+)MAPPERmRatBN7.2
Rnor_6.0X71,335,683 - 71,335,812NCBIRnor6.0
Rnor_5.0X72,186,375 - 72,186,504UniSTSRnor5.0
RGSC_v3.4X89,513,636 - 89,513,765UniSTSRGSC3.4
CeleraX66,921,120 - 66,921,249UniSTS
Cytogenetic MapXq31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000004911   ⟹   ENSRNOP00000004911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX70,593,888 - 70,611,979 (+)Ensembl
mRatBN7.2 EnsemblX66,554,098 - 66,571,952 (+)Ensembl
Rnor_6.0 EnsemblX71,324,365 - 71,342,225 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000076003   ⟹   ENSRNOP00000068383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX71,335,491 - 71,336,207 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160292   ⟹   ENSRNOP00000103644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX70,593,888 - 70,611,979 (+)Ensembl
RefSeq Acc Id: NM_001012356   ⟹   NP_001012356
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X70,594,116 - 70,611,976 (+)NCBI
mRatBN7.2X66,554,131 - 66,571,992 (+)NCBI
Rnor_6.0X71,324,365 - 71,342,225 (+)NCBI
Rnor_5.0X72,175,019 - 72,192,921 (+)NCBI
RGSC_v3.4X89,502,318 - 89,520,178 (+)RGD
CeleraX66,909,811 - 66,927,662 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001012356 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH89880 (Get FASTA)   NCBI Sequence Viewer  
  EDL95893 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004911
  ENSRNOP00000004911.4
GenBank Protein Q5FVM4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012356   ⟸   NM_001012356
- UniProtKB: Q5FVM4 (UniProtKB/Swiss-Prot),   A6IQC0 (UniProtKB/TrEMBL),   A6IQB9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004911   ⟸   ENSRNOT00000004911
Ensembl Acc Id: ENSRNOP00000068383   ⟸   ENSRNOT00000076003
Ensembl Acc Id: ENSRNOP00000103644   ⟸   ENSRNOT00000160292
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVM4-F1-model_v2 AlphaFold Q5FVM4 1-476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701877
Promoter ID:EPDNEW_R12401
Type:initiation region
Name:Nono_1
Description:non-POU domain containing, octamer-binding
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X71,324,357 - 71,324,417EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1549738 AgrOrtholog
BioCyc Gene G2FUF-2099 BioCyc
Ensembl Genes ENSRNOG00000003689 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004911 ENTREZGENE
  ENSRNOT00000004911.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
  6.10.250.1170 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7366190 IMAGE-MGC_LOAD
InterPro NOPS UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  p54nrb_RRM1 UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
KEGG Report rno:317259 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109026 IMAGE-MGC_LOAD
NCBI Gene 317259 ENTREZGENE
PANTHER RNA RECOGNITION MOTIF-CONTAINING UniProtKB/Swiss-Prot
Pfam NOPS UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Nono PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003689 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0ABK0LR13_RAT UniProtKB/TrEMBL
  A6IQB9 ENTREZGENE, UniProtKB/TrEMBL
  A6IQC0 ENTREZGENE, UniProtKB/TrEMBL
  NONO_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-26 Nono  non-POU domain containing, octamer-binding  Nono  non-POU-domain-containing, octamer-binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Nono  non-POU-domain-containing, octamer-binding protein  Nono  non-POU domain containing, octamer-binding  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-15 Nono  non-POU domain containing, octamer-binding      Symbol and Name status set to provisional 70820 PROVISIONAL