Golga7 (golgin A7) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Golga7 (golgin A7) Rattus norvegicus
Analyze
Symbol: Golga7
Name: golgin A7
RGD ID: 1359725
Description: Predicted to be involved in establishment of protein localization to membrane; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Predicted to act upstream of or within Golgi to plasma membrane transport. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi stack. Orthologous to human GOLGA7 (golgin A7); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: golgi autoantigen, golgin subfamily a, 7; golgin subfamily A member 7; MGC93825
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81675,469,794 - 75,485,055 (+)NCBIGRCr8
mRatBN7.21668,767,259 - 68,782,536 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1668,767,299 - 68,782,511 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,107,114 - 50,107,622 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0358,690,627 - 58,691,135 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0356,463,609 - 56,464,117 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01673,564,172 - 73,579,389 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1673,564,243 - 73,579,382 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,198,435 - 73,213,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,225,605 - 73,240,751 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11673,225,869 - 73,241,013 (+)NCBI
Celera1666,658,822 - 66,673,968 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi membrane  (IEA,ISO,ISS)
Golgi stack  (IBA,IEA,ISO,ISS)
palmitoyltransferase complex  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
5. DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. Swarthout JT, etal., J Biol Chem. 2005 Sep 2;280(35):31141-8. Epub 2005 Jul 6.
Additional References at PubMed
PMID:14522980   PMID:15489334   PMID:19056867   PMID:20458337   PMID:22871113   PMID:23376485  


Genomics

Comparative Map Data
Golga7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81675,469,794 - 75,485,055 (+)NCBIGRCr8
mRatBN7.21668,767,259 - 68,782,536 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1668,767,299 - 68,782,511 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,107,114 - 50,107,622 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0358,690,627 - 58,691,135 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0356,463,609 - 56,464,117 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01673,564,172 - 73,579,389 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1673,564,243 - 73,579,382 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01673,198,435 - 73,213,647 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,225,605 - 73,240,751 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11673,225,869 - 73,241,013 (+)NCBI
Celera1666,658,822 - 66,673,968 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
GOLGA7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38841,490,396 - 41,510,980 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl841,488,200 - 41,511,095 (+)EnsemblGRCh38hg38GRCh38
GRCh37841,347,915 - 41,368,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36841,467,238 - 41,487,656 (+)NCBINCBI36Build 36hg18NCBI36
Build 34841,467,237 - 41,487,654NCBI
Celera840,297,177 - 40,317,582 (+)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef839,875,887 - 39,896,291 (+)NCBIHuRef
CHM1_1841,396,465 - 41,416,889 (+)NCBICHM1_1
T2T-CHM13v2.0841,764,091 - 41,784,672 (+)NCBIT2T-CHM13v2.0
Golga7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39823,731,342 - 23,747,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl823,731,362 - 23,747,090 (-)EnsemblGRCm39 Ensembl
GRCm38823,241,326 - 23,258,903 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl823,241,346 - 23,257,074 (-)EnsemblGRCm38mm10GRCm38
MGSCv37824,351,798 - 24,367,552 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36824,706,892 - 24,722,557 (-)NCBIMGSCv36mm8
Celera824,738,054 - 24,753,828 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map811.42NCBI
Golga7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555361,386,652 - 1,408,727 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555361,386,760 - 1,408,628 (-)NCBIChiLan1.0ChiLan1.0
GOLGA7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2759,942,484 - 59,964,360 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1835,659,769 - 35,681,645 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0840,736,824 - 40,756,458 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1838,187,126 - 38,206,721 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl838,185,103 - 38,206,714 (+)Ensemblpanpan1.1panPan2
GOLGA7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11624,083,498 - 24,102,024 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1624,084,540 - 24,102,440 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1624,588,238 - 24,606,766 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01625,831,453 - 25,849,948 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1625,831,453 - 25,849,809 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11624,203,309 - 24,221,832 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01624,765,424 - 24,783,951 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01624,816,764 - 24,835,294 (-)NCBIUU_Cfam_GSD_1.0
Golga7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494347,116,521 - 47,133,551 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367851,072,909 - 1,089,945 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367851,072,917 - 1,089,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GOLGA7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1710,623,797 - 10,644,296 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11710,624,378 - 10,643,844 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21711,988,599 - 12,008,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GOLGA7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1839,471,721 - 39,491,555 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl839,471,668 - 39,491,866 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660522,328,705 - 2,348,651 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Golga7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247801,764,863 - 1,787,569 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247801,766,821 - 1,787,405 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Golga7
61 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:129
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000030960
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat
1298527Arunc2Aerobic running capacity QTL 22.9exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)166853271675029966Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat

Markers in Region
RH129313  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map16620.4UniSTS
Cytogenetic Map16q12.5UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000030960   ⟹   ENSRNOP00000033324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1668,767,358 - 68,782,511 (+)Ensembl
Rnor_6.0 Ensembl1673,564,243 - 73,579,382 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096293   ⟹   ENSRNOP00000077876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1668,767,299 - 68,782,401 (+)Ensembl
RefSeq Acc Id: NM_001007731   ⟹   NP_001007732
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81675,469,909 - 75,485,055 (+)NCBI
mRatBN7.21668,767,375 - 68,782,521 (+)NCBI
Rnor_6.01673,564,243 - 73,579,389 (+)NCBI
Rnor_5.01673,198,435 - 73,213,647 (+)NCBI
RGSC_v3.41673,225,605 - 73,240,751 (+)RGD
Celera1666,658,822 - 66,673,968 (+)RGD
Sequence:
RefSeq Acc Id: XM_017600185   ⟹   XP_017455674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81675,469,794 - 75,485,055 (+)NCBI
mRatBN7.21668,767,259 - 68,782,536 (+)NCBI
Rnor_6.01673,564,172 - 73,579,389 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094672   ⟹   XP_038950600
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81675,469,840 - 75,485,055 (+)NCBI
mRatBN7.21668,767,332 - 68,782,536 (+)NCBI
RefSeq Acc Id: XM_063275571   ⟹   XP_063131641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81675,469,794 - 75,485,055 (+)NCBI
RefSeq Acc Id: NP_001007732   ⟸   NM_001007731
- UniProtKB: Q6AYQ1 (UniProtKB/Swiss-Prot),   A6IW41 (UniProtKB/TrEMBL),   A0A8L2QIB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455674   ⟸   XM_017600185
- Peptide Label: isoform X1
- UniProtKB: Q6AYQ1 (UniProtKB/Swiss-Prot),   A6IW41 (UniProtKB/TrEMBL),   A0A8L2QIB4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033324   ⟸   ENSRNOT00000030960
RefSeq Acc Id: XP_038950600   ⟸   XM_039094672
- Peptide Label: isoform X1
- UniProtKB: Q6AYQ1 (UniProtKB/Swiss-Prot),   A6IW41 (UniProtKB/TrEMBL),   A0A8L2QIB4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077876   ⟸   ENSRNOT00000096293
RefSeq Acc Id: XP_063131641   ⟸   XM_063275571
- Peptide Label: isoform X2
Protein Domains
Golgin subfamily A member 7/ERF4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYQ1-F1-model_v2 AlphaFold Q6AYQ1 1-137 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700179
Promoter ID:EPDNEW_R10703
Type:initiation region
Name:Golga7_1
Description:golgin A7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01673,564,193 - 73,564,253EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359725 AgrOrtholog
BioCyc Gene G2FUF-10901 BioCyc
Ensembl Genes ENSRNOG00000017956 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030960.4 UniProtKB/TrEMBL
  ENSRNOT00000096293.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7110849 IMAGE-MGC_LOAD
InterPro Golgin_A_7/ERF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ras_palmitoyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361171 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93825 IMAGE-MGC_LOAD
NCBI Gene 361171 ENTREZGENE
PANTHER GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLGIN SUBFAMILY A MEMBER 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Erf4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Golga7 PhenoGen
RatGTEx ENSRNOG00000017956 RatGTEx
UniProt A0A8I5Y7Z1_RAT UniProtKB/TrEMBL
  A0A8L2QIB4 ENTREZGENE, UniProtKB/TrEMBL
  A6IW41 ENTREZGENE, UniProtKB/TrEMBL
  GOGA7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Golga7  golgin A7  Golga7  golgi autoantigen, golgin subfamily a, 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Golga7  golgi autoantigen, golgin subfamily a, 7      Symbol and Name status set to provisional 70820 PROVISIONAL